HUP0300556A2 - Oldószermentes extrakciós eljárás - Google Patents

Oldószermentes extrakciós eljárás

Info

Publication number
HUP0300556A2
HUP0300556A2 HU0300556A HUP0300556A HUP0300556A2 HU P0300556 A2 HUP0300556 A2 HU P0300556A2 HU 0300556 A HU0300556 A HU 0300556A HU P0300556 A HUP0300556 A HU P0300556A HU P0300556 A2 HUP0300556 A2 HU P0300556A2
Authority
HU
Hungary
Prior art keywords
layer
lipids
microorganisms
light layer
lipid
Prior art date
Application number
HU0300556A
Other languages
English (en)
Inventor
Swithin Patrick Adu-Peasah
Brian S. Engelhardt
Craig M. Ruecker
George T. Veeder Iii
Original Assignee
Omegatech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22647287&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0300556(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Omegatech, Inc. filed Critical Omegatech, Inc.
Publication of HUP0300556A2 publication Critical patent/HUP0300556A2/hu
Publication of HUP0300556A3 publication Critical patent/HUP0300556A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11BPRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00Production of fats or fatty oils from raw materials
    • C11B1/02Pretreatment
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11BPRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00Refining fats or fatty oils
    • C11B3/006Refining fats or fatty oils by extraction
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11BPRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00Refining fats or fatty oils
    • C11B3/001Refining fats or fatty oils by a combination of two or more of the means hereafter
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06Lysis of microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P25/00Preparation of compounds containing alloxazine or isoalloxazine nucleus, e.g. riboflavin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432Eicosapentaenoic acids [EPA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434Docosahexenoic acids [DHA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6463Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone

Abstract

A találmány lipidek mikroorganizmusokból történő extrahálásáravonatkozik nempoláros szerves oldószer alkalmazása nélkül. A találmányszerinti eljárás lipid előállítására mikroorganizmusokból azalábbiakból áll: (a) a mikroorganizmusok sejtjét lizálják, így lizáltsejtelegyet állítanak elő; (b) a lizált sejtelegyet kezelik, így egynehéz rétegből és egy könnyű rétegből álló, elválasztott fázisúelegyet állítanak elő; ahol a nehéz réteg vizes oldatból áll, és akönnyű réteg tartalmazza a lipidet; (c) a kapott nehéz rétegetelválasztják a könnyű rétegtől; és (d) a lipidet kinyerik a könnyűrétegből. A találmány az előállított lipideket is magában foglalja. Ó
HU0300556A 2000-01-19 2001-01-19 Solventless extraction process HUP0300556A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17712500P 2000-01-19 2000-01-19
PCT/US2001/001806 WO2001053512A1 (en) 2000-01-19 2001-01-19 Solventless extraction process

Publications (2)

Publication Number Publication Date
HUP0300556A2 true HUP0300556A2 (hu) 2003-06-28
HUP0300556A3 HUP0300556A3 (en) 2010-03-29

Family

ID=22647287

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0300556A HUP0300556A3 (en) 2000-01-19 2001-01-19 Solventless extraction process

Country Status (24)

Country Link
US (8) US6750048B2 (hu)
EP (4) EP1252324B1 (hu)
JP (5) JP4020642B2 (hu)
KR (8) KR101429236B1 (hu)
CN (1) CN100460513C (hu)
AT (1) ATE485385T1 (hu)
AU (7) AU780619B2 (hu)
BR (1) BR0107699B1 (hu)
CA (2) CA2397655C (hu)
CZ (1) CZ303446B6 (hu)
DE (1) DE60143287D1 (hu)
DK (1) DK1252324T3 (hu)
ES (3) ES2735987T3 (hu)
HK (1) HK1050716A1 (hu)
HU (1) HUP0300556A3 (hu)
IL (5) IL150772A0 (hu)
MX (4) MX232239B (hu)
NO (2) NO20023449L (hu)
NZ (1) NZ520287A (hu)
PL (1) PL356587A1 (hu)
PT (1) PT1252324E (hu)
RU (1) RU2336307C2 (hu)
WO (1) WO2001053512A1 (hu)
ZA (1) ZA200205790B (hu)

Families Citing this family (200)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7776353B1 (en) 1998-03-17 2010-08-17 Aker Biomarine Asa Conjugated linoleic acid compositions
ATE350028T1 (de) 1998-03-17 2007-01-15 Natural Asa Konjugierte linolsäurezusammensetzung
US7078051B1 (en) 1998-08-11 2006-07-18 Natural Asa Conjugated linoleic acid alkyl esters in feedstuffs and food
US7101914B2 (en) 1998-05-04 2006-09-05 Natural Asa Isomer enriched conjugated linoleic acid compositions
EP1252324B1 (en) * 2000-01-19 2010-10-20 Martek Biosciences Corporation Solventless extraction process
CA2404799C (en) * 2000-04-06 2007-08-07 Conlinco, Inc. Conjugated linoleic acid compositions
EP1274320A2 (en) 2000-04-18 2003-01-15 Natural AS Conjugated linoleic acid powder
EP1178118A1 (en) * 2000-08-02 2002-02-06 Dsm N.V. Isolation of microbial oils
US6677470B2 (en) 2001-11-20 2004-01-13 Natural Asa Functional acylglycerides
US7419596B2 (en) * 2001-12-12 2008-09-02 Martek Biosciences Corporation Extraction and winterization of lipids from oilseed and microbial sources
EP2266525B1 (en) 2002-05-03 2012-07-11 Martek Biosciences Corporation High quality lipids and methods for producing by enzymatic liberation from biomass
US6743931B2 (en) 2002-09-24 2004-06-01 Natural Asa Conjugated linoleic acid compositions
AU2004280575B8 (en) 2003-10-02 2010-05-13 Dsm Ip Assets B.V. Production of high levels of DHA in microalgae using modified amounts of chloride and potassium
WO2005072477A2 (en) 2004-01-26 2005-08-11 Martek Biosciences Corporation Method for the separation of phospholipids from phospholipid-containing materials
AU2006227165B2 (en) 2005-03-18 2011-11-10 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
US8048652B2 (en) * 2005-05-12 2011-11-01 Martek Biosciences Corporation Biomass hydrolysate and uses and production thereof
EP2447356B1 (en) 2005-06-07 2016-04-20 DSM Nutritional Products AG Eukaryotic microorganisms for producing lipids and antioxidants
MX300085B (es) 2005-07-01 2012-06-08 Martek Biosciences Corp Producto oleoso que contiene acido graso poli-insaturado y usos y produccion del mismo.
US8298548B2 (en) 2007-07-18 2012-10-30 Solazyme, Inc. Compositions for improving the health and appearance of skin
US8277849B2 (en) * 2006-01-19 2012-10-02 Solazyme, Inc. Microalgae-derived compositions for improving the health and appearance of skin
US20100242345A1 (en) 2006-05-19 2010-09-30 LS9, Inc Production of fatty acids & derivatives thereof
US8110670B2 (en) * 2006-05-19 2012-02-07 Ls9, Inc. Enhanced production of fatty acid derivatives
JP5658876B2 (ja) * 2006-07-05 2015-01-28 フォトンズ コーポレーション リミテッド 大規模従属栄養培養領域にて産生される超高純度epaと極性脂質
JP4854418B2 (ja) * 2006-07-28 2012-01-18 花王株式会社 ドデカヒドロ−3a,6,6,9a−テトラメチルナフト[2,1−b]フラン原料の製造方法
MX2009001346A (es) * 2006-08-01 2009-04-17 Ocean Nutrition Canada Ltd Microbios productores de aceite y metodos de modificacion de los mismos.
WO2008042338A2 (en) 2006-09-28 2008-04-10 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
US8262776B2 (en) * 2006-10-13 2012-09-11 General Atomics Photosynthetic carbon dioxide sequestration and pollution abatement
US8088614B2 (en) * 2006-11-13 2012-01-03 Aurora Algae, Inc. Methods and compositions for production and purification of biofuel from plants and microalgae
WO2008124048A2 (en) * 2007-04-03 2008-10-16 E. I. Du Pont De Nemours And Company Multizymes and their use in making polyunsaturated fatty acids
MY154965A (en) 2007-06-01 2015-08-28 Solazyme Inc Production of oil in microorganisms
WO2008155410A1 (en) * 2007-06-21 2008-12-24 Novozymes A/S Production of lipids containing poly-unsaturated fatty acids
AU2008269989B2 (en) * 2007-06-29 2014-02-27 Dsm Ip Assets B.V. Production and purification of esters of polyunsaturated fatty acids
CN113846129A (zh) 2007-09-12 2021-12-28 帝斯曼知识产权资产管理有限公司 生物油及其制备与应用
CA2692266C (en) * 2007-09-27 2019-04-16 Ls9, Inc. Reduction of the toxic effect of impurities from raw materials by extractive fermentation
EP2211881A4 (en) * 2007-11-01 2012-01-04 Wake Forest University School Of Medicine COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING DISEASES AFFECTING MAMMALS
US8343753B2 (en) * 2007-11-01 2013-01-01 Wake Forest University School Of Medicine Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
EP2297326A4 (en) 2008-06-06 2011-11-16 Aurora Biofuels Inc VCP-BASED VECTORS FOR THE TRANSFORMATION OF ALGAE CELLS
US20100022393A1 (en) * 2008-07-24 2010-01-28 Bertrand Vick Glyphosate applications in aquaculture
US20100236137A1 (en) * 2008-09-23 2010-09-23 LiveFuels, Inc. Systems and methods for producing eicosapentaenoic acid and docosahexaenoic acid from algae
US20100077654A1 (en) * 2008-09-23 2010-04-01 LiveFuels, Inc. Systems and methods for producing biofuels from algae
US20100297323A1 (en) * 2008-10-14 2010-11-25 Solazyme, Inc. Gluten-free Foods Containing Microalgae
US20100297325A1 (en) * 2008-10-14 2010-11-25 Solazyme, Inc. Egg Products Containing Microalgae
US20100303989A1 (en) * 2008-10-14 2010-12-02 Solazyme, Inc. Microalgal Flour
US9896642B2 (en) 2008-10-14 2018-02-20 Corbion Biotech, Inc. Methods of microbial oil extraction and separation
US20100303957A1 (en) * 2008-10-14 2010-12-02 Solazyme, Inc. Edible Oil and Processes for Its Production from Microalgae
US20100297295A1 (en) * 2008-10-14 2010-11-25 Solazyme, Inc. Microalgae-Based Beverages
US20100297331A1 (en) * 2008-10-14 2010-11-25 Solazyme, Inc. Reduced Fat Foods Containing High-Lipid Microalgae with Improved Sensory Properties
US8927522B2 (en) 2008-10-14 2015-01-06 Solazyme, Inc. Microalgal polysaccharide compositions
US20100303990A1 (en) * 2008-10-14 2010-12-02 Solazyme, Inc. High Protein and High Fiber Algal Food Materials
US20100303961A1 (en) * 2008-10-14 2010-12-02 Solazyme, Inc. Methods of Inducing Satiety
US20100239712A1 (en) * 2008-10-14 2010-09-23 Solazyme, Inc. Food Compositions of Microalgal Biomass
US8809037B2 (en) 2008-10-24 2014-08-19 Bioprocessh20 Llc Systems, apparatuses and methods for treating wastewater
US8557249B2 (en) 2008-11-07 2013-10-15 Solazyme, Inc. Cosmetic compositions comprising microalgal components
WO2010059598A1 (en) * 2008-11-18 2010-05-27 LiveFuels, Inc. Methods for producing fish with high lipid content
MX2011005630A (es) 2008-11-28 2011-09-28 Solazyme Inc Producción de aceites específicos en microorganismos heterótroficos recombinantes.
EP2373803A4 (en) * 2008-12-08 2013-05-29 Sapphire Energy Inc REMOVAL OF NITROGEN FROM CHLOROPHYLL OR PHEOPHYTIC BIOMASS
US8940340B2 (en) * 2009-01-22 2015-01-27 Aurora Algae, Inc. Systems and methods for maintaining the dominance of Nannochloropsis in an algae cultivation system
CN104042600A (zh) 2009-02-02 2014-09-17 帝斯曼知识产权资产有限公司 改善认知功能和降低心率的方法
US8143051B2 (en) * 2009-02-04 2012-03-27 Aurora Algae, Inc. Systems and methods for maintaining the dominance and increasing the biomass production of nannochloropsis in an algae cultivation system
SE534278C2 (sv) * 2009-02-17 2011-06-28 Alfa Laval Corp Ab Ett kontinuerligt förfarande för isolering av oljor från alger eller mikroorganismer
WO2010107415A1 (en) 2009-03-19 2010-09-23 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
US8207363B2 (en) * 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
US8476060B2 (en) * 2009-04-13 2013-07-02 Board Of Regents, The University Of Texas System Process for separating lipids from a biomass
US8753851B2 (en) 2009-04-17 2014-06-17 LiveFuels, Inc. Systems and methods for culturing algae with bivalves
US20100297749A1 (en) * 2009-04-21 2010-11-25 Sapphire Energy, Inc. Methods and systems for biofuel production
WO2010124125A2 (en) * 2009-04-22 2010-10-28 Robert Fulton Fluidizable algae-based powdered fuel and methods for making and using same
BRPI1015313B1 (pt) 2009-04-27 2021-06-01 Genomatica, Inc. Método fermentativo para produzir um éster de ácido graxo empregando um microorganismo geneticamente modificado e método para a produção de ésteres de ácidos graxos
US9187778B2 (en) 2009-05-04 2015-11-17 Aurora Algae, Inc. Efficient light harvesting
BRPI1012026A2 (pt) 2009-05-26 2018-07-17 Solazyme Inc fracionamento de biomassa microbiana contendo óleo
US8865468B2 (en) * 2009-10-19 2014-10-21 Aurora Algae, Inc. Homologous recombination in an algal nuclear genome
US8809046B2 (en) 2011-04-28 2014-08-19 Aurora Algae, Inc. Algal elongases
US9029137B2 (en) 2009-06-08 2015-05-12 Aurora Algae, Inc. ACP promoter
US8865452B2 (en) * 2009-06-15 2014-10-21 Aurora Algae, Inc. Systems and methods for extracting lipids from wet algal biomass
US9101942B2 (en) * 2009-06-16 2015-08-11 Aurora Algae, Inc. Clarification of suspensions
US8769867B2 (en) * 2009-06-16 2014-07-08 Aurora Algae, Inc. Systems, methods, and media for circulating fluid in an algae cultivation pond
US8747930B2 (en) * 2009-06-29 2014-06-10 Aurora Algae, Inc. Siliceous particles
US20100325948A1 (en) * 2009-06-29 2010-12-30 Mehran Parsheh Systems, methods, and media for circulating and carbonating fluid in an algae cultivation pond
CN101585759B (zh) * 2009-07-08 2012-05-23 内蒙古金达威药业有限公司 从双鞭甲藻发酵液中提取dha不饱和脂肪酸的方法
US20110177061A1 (en) 2009-07-10 2011-07-21 Martek Biosciences Corporation Methods of treating and preventing neurological disorders using docosahexaenoic acid
WO2011011463A2 (en) * 2009-07-20 2011-01-27 Aurora Biofuels, Inc. Manipulation of an alternative respiratory pathway in photo-autotrophs
US20110082205A1 (en) 2009-10-01 2011-04-07 Panker Cynthia A Docosahexaenoic Acid Gel Caps
US8765983B2 (en) * 2009-10-30 2014-07-01 Aurora Algae, Inc. Systems and methods for extracting lipids from and dehydrating wet algal biomass
US8748160B2 (en) * 2009-12-04 2014-06-10 Aurora Alage, Inc. Backward-facing step
WO2011082190A1 (en) 2009-12-28 2011-07-07 Martek Biosciences Corporation Recombinant thraustochytrids that grow on sucrose, and compositions, methods of making, and uses thereof
CN102906270B (zh) * 2009-12-28 2016-06-22 Dsmip资产公司 在木糖上生长的重组破囊壶菌和其组合物、制备方法及用途
BR112012017831B8 (pt) 2010-01-19 2021-05-25 Dsm Ip Assets Bv óleo microbiano, alimento animal e biomassa compreendendo o referido óleo microbiano
US8303818B2 (en) * 2010-06-24 2012-11-06 Streamline Automation, Llc Method and apparatus using an active ionic liquid for algae biofuel harvest and extraction
KR20130048218A (ko) 2010-04-06 2013-05-09 헬리아에 디벨롭먼트, 엘엘씨 조류의 탈수 및 그것으로부터의 물을 재사용하기 위한 방법 및 시스템
WO2011127127A2 (en) 2010-04-06 2011-10-13 Arizona Board Of Regents For And On Behalf Of Arizona State University Extraction with fractionation of oil and co-products from oleaginous material
US8308951B1 (en) 2010-04-06 2012-11-13 Heliae Development, Llc Extraction of proteins by a two solvent method
US8115022B2 (en) 2010-04-06 2012-02-14 Heliae Development, Llc Methods of producing biofuels, chlorophylls and carotenoids
US8211309B2 (en) 2010-04-06 2012-07-03 Heliae Development, Llc Extraction of proteins by a two solvent method
US8313648B2 (en) 2010-04-06 2012-11-20 Heliae Development, Llc Methods of and systems for producing biofuels from algal oil
US8211308B2 (en) 2010-04-06 2012-07-03 Heliae Development, Llc Extraction of polar lipids by a two solvent method
US8273248B1 (en) 2010-04-06 2012-09-25 Heliae Development, Llc Extraction of neutral lipids by a two solvent method
US8475660B2 (en) 2010-04-06 2013-07-02 Heliae Development, Llc Extraction of polar lipids by a two solvent method
US8202425B2 (en) 2010-04-06 2012-06-19 Heliae Development, Llc Extraction of neutral lipids by a two solvent method
US10125331B2 (en) * 2010-04-29 2018-11-13 Advanced Energy Development Renewable oil refining processes
MX339639B (es) 2010-05-28 2016-06-02 Solazyme Inc * Aceites especificos producidos a partir de microorganismos heterotrofos recombinantes.
JP5911479B2 (ja) * 2010-06-01 2016-04-27 ディーエスエム アイピー アセッツ ビー.ブイ. 細胞からの脂質の抽出およびそれに由来する生産物
NL2004832C2 (en) * 2010-06-07 2011-12-08 Evodos B V Separating biomass from an aqueous medium.
WO2011159682A1 (en) 2010-06-14 2011-12-22 Raveendran Pottathil Methods for the production of algae derived oils
US9028696B2 (en) 2010-07-26 2015-05-12 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds from biomass
MA34468B1 (fr) 2010-07-26 2013-08-01 Sapphire Energy Inc Procédé pour récupérer des composés oléagineux à partir d'une biomasse
US8906236B2 (en) 2010-07-26 2014-12-09 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds and nutrients from biomass
EP2619297A1 (en) 2010-09-21 2013-07-31 Shell Internationale Research Maatschappij B.V. Process for separation of a mixture containing a microbial oil and a microbial substance
SG10201509035WA (en) 2010-11-03 2015-12-30 Solazyme Inc Microbial Oils With Lowered Pour Points, Dielectric Fluids Produced Therefrom, And Related Methods
US20120329138A1 (en) 2010-12-23 2012-12-27 Shell Oil Company Process for separation of a mixture containing a microbial substance and a liquid
US8722359B2 (en) 2011-01-21 2014-05-13 Aurora Algae, Inc. Genes for enhanced lipid metabolism for accumulation of lipids
CN102617431B (zh) * 2011-01-28 2013-09-25 天津滨海索尔特生物技术中心有限公司 用无机碱提取盐藻中的β-胡萝卜素的方法
MX344012B (es) 2011-02-02 2016-12-02 Terravia Holdings Inc Aceites adaptados producidos a partir de microorganismos oleaginosos recombinantes.
US20140096437A1 (en) * 2011-02-16 2014-04-10 Richard Crowell Compositions and methods for leach extraction of microorganisms
US8926844B2 (en) 2011-03-29 2015-01-06 Aurora Algae, Inc. Systems and methods for processing algae cultivation fluid
US8569530B2 (en) 2011-04-01 2013-10-29 Aurora Algae, Inc. Conversion of saponifiable lipids into fatty esters
JP2014519810A (ja) 2011-04-28 2014-08-21 オーロラ アルギー,インコーポレイテッド 藻類のデサチュラーゼ
US8752329B2 (en) 2011-04-29 2014-06-17 Aurora Algae, Inc. Optimization of circulation of fluid in an algae cultivation pond
US9487716B2 (en) 2011-05-06 2016-11-08 LiveFuels, Inc. Sourcing phosphorus and other nutrients from the ocean via ocean thermal energy conversion systems
CN103608450A (zh) 2011-05-06 2014-02-26 索拉兹米公司 基因工程改造的代谢木糖的微生物
US20140099684A1 (en) * 2011-05-26 2014-04-10 Council Of Scientific & Industrial Research Engine worthy fatty acid methyl ester (biodiesel) from naturally occuring marine microalgal mats and marine microalgae cultured in open salt pans together with value addition of co-products
FR2975705B1 (fr) * 2011-05-27 2014-12-26 Roquette Freres Procede d'extraction du squalene a partir de microalgues
US8365462B2 (en) 2011-05-31 2013-02-05 Heliae Development, Llc V-Trough photobioreactor systems
USD661164S1 (en) 2011-06-10 2012-06-05 Heliae Development, Llc Aquaculture vessel
USD679965S1 (en) 2011-06-10 2013-04-16 Heliae Development, Llc Aquaculture vessel
USD682637S1 (en) 2011-06-10 2013-05-21 Heliae Development, Llc Aquaculture vessel
MX342216B (es) 2011-07-21 2016-09-20 Dsm Ip Assets Bv Composiciones de acidos grasos.
KR102038715B1 (ko) 2011-07-21 2019-10-31 디에스엠 아이피 어셋츠 비.브이. 에이코사펜타엔산-생산 미생물, 지방산 조성물, 및 이의 생산 방법 및 용도
WO2013024174A1 (en) 2011-08-18 2013-02-21 Dsm Ip Assets B.V. Dha triglyceride, dha free fatty acid, and dha ethyl ester emulsions, and methods of treating spinal cord injury
JP2014532773A (ja) 2011-11-01 2014-12-08 ディーエスエム アイピー アセッツ ビー.ブイ. 酸化安定性多価不飽和脂肪酸を含有する油
US9200236B2 (en) 2011-11-17 2015-12-01 Heliae Development, Llc Omega 7 rich compositions and methods of isolating omega 7 fatty acids
CN103131529B (zh) * 2011-11-23 2016-02-24 丰益(上海)生物技术研发中心有限公司 一种提取微生物油脂的方法
EP3550025A1 (en) 2012-04-18 2019-10-09 Corbion Biotech, Inc. Tailored oils
CN103421595A (zh) * 2012-05-25 2013-12-04 丰益(上海)生物技术研发中心有限公司 一种提取微生物油脂的方法
EP2867355A1 (en) 2012-06-29 2015-05-06 BP Biofuels UK Ltd. Process for separation of renewable materials from microorganisms
CN103589503B (zh) * 2012-08-13 2015-09-30 丰益(上海)生物技术研发中心有限公司 一种高效提取微生物油脂的方法
KR101470078B1 (ko) * 2012-08-21 2014-12-08 현대자동차주식회사 이산화탄소 포집ㆍ고정ㆍ전환을 통한 온실가스 감축 및 부가가치화 방법
US10098371B2 (en) 2013-01-28 2018-10-16 Solazyme Roquette Nutritionals, LLC Microalgal flour
US9567615B2 (en) 2013-01-29 2017-02-14 Terravia Holdings, Inc. Variant thioesterases and methods of use
US9816079B2 (en) 2013-01-29 2017-11-14 Terravia Holdings, Inc. Variant thioesterases and methods of use
EP2762009A1 (de) * 2013-02-05 2014-08-06 Evonik Industries AG Verbesserung der Bioverfügbarkeit von Wertstoffen aus Mikroorganismen
EP2953480B1 (de) * 2013-02-05 2020-06-03 Evonik Operations GmbH Verbesserung der bioverfügbarkeit von wertstoffen aus mikroorganismen
US9873880B2 (en) 2013-03-13 2018-01-23 Dsm Nutritional Products Ag Engineering microorganisms
US9290749B2 (en) 2013-03-15 2016-03-22 Solazyme, Inc. Thioesterases and cells for production of tailored oils
US9266973B2 (en) 2013-03-15 2016-02-23 Aurora Algae, Inc. Systems and methods for utilizing and recovering chitosan to process biological material
US9783836B2 (en) 2013-03-15 2017-10-10 Terravia Holdings, Inc. Thioesterases and cells for production of tailored oils
US9597280B2 (en) 2013-05-15 2017-03-21 Terravia Holdings, Inc. Cosmetic compositions comprising microalgal oil
EP2826384A1 (de) 2013-07-16 2015-01-21 Evonik Industries AG Verfahren zur Trocknung von Biomasse
FR3009619B1 (fr) 2013-08-07 2017-12-29 Roquette Freres Compositions de biomasse de microalgues riches en proteines de qualite sensorielle optimisee
AU2014331605A1 (en) 2013-10-04 2016-05-12 Corbion Biotech, Inc. Tailored oils
KR102143001B1 (ko) * 2013-11-01 2020-08-11 에스케이이노베이션 주식회사 초음속 분산기를 이용한 유질 미생물 파쇄 공정 및 이를 이용한 바이오 오일의 제조방법
US11124736B2 (en) 2013-12-20 2021-09-21 Dsm Ip Assets B.V. Processes for obtaining microbial oil from microbial cells
KR102435268B1 (ko) * 2013-12-20 2022-08-22 디에스엠 뉴트리셔널 프라덕츠 아게 미생물로부터 오일을 회수하는 방법
CN115141859A (zh) 2013-12-20 2022-10-04 玛拉可再生能源公司 从微生物中回收油的方法
NZ721417A (en) 2013-12-20 2022-07-01 Dsm Ip Assets Bv Processes for obtaining microbial oil from microbial cells
JP2017501709A (ja) 2013-12-20 2017-01-19 ディーエスエム アイピー アセッツ ビー.ブイ. 微生物細胞から微生物油を入手する方法
SG11201605052XA (en) 2013-12-20 2016-07-28 Dsm Ip Assets Bv Processes for obtaining microbial oil from microbial cells
JP2017500041A (ja) * 2013-12-20 2017-01-05 ディーエスエム アイピー アセッツ ビー.ブイ. 微生物細胞から微生物油を入手する方法
BR112017000414A2 (pt) 2014-07-10 2017-11-07 Terravia Holdings Inc genes cetoacil-acp sintase e utilizações dos mesmos
US9765368B2 (en) 2014-07-24 2017-09-19 Terravia Holdings, Inc. Variant thioesterases and methods of use
EP3194582A2 (en) 2014-09-18 2017-07-26 TerraVia Holdings, Inc. Acyl-acp thioesterases and mutants thereof
BR112017006833B1 (pt) 2014-10-02 2022-09-13 Evonik Operations Gmbh Alimento para animais contendo ácido graxo poli-insaturado e processo para produzir o mesmo
EP3200604B1 (de) 2014-10-02 2021-11-03 Evonik Operations GmbH Verfahren zur herstellung eines futtermittels
CA2958460C (en) 2014-10-02 2022-09-13 Evonik Industries Ag Process for producing a pufa-containing feedstuff by extruding a pufa-containing biomass
CA2958457C (en) 2014-10-02 2022-10-25 Evonik Industries Ag Process for producing a pufa-containing biomass which has high cell stability
WO2016102177A1 (en) 2014-12-22 2016-06-30 Unilever Plc Hair composition
KR20160096478A (ko) * 2015-02-05 2016-08-16 주식회사 이코원 탄소 발열 모듈 및 이를 이용한 탄소 발열 튀김기
AR104042A1 (es) 2015-03-26 2017-06-21 Mara Renewables Corp Producción de alta densidad de biomasa y aceite utilizando glicerol en bruto
WO2016156528A1 (en) 2015-03-31 2016-10-06 Fresenius Kabi Deutschland Gmbh Emulsions for parenteral administration
US20160298104A1 (en) * 2015-04-07 2016-10-13 Decant Treatment Systems, Llc Method for electrical treatment of fluid medium containing biological matter and a system for its implementation
US10342775B2 (en) 2015-05-22 2019-07-09 Fresenius Kabi Deutschland Gmbh Vitamin A for parenteral administration
WO2016188876A1 (en) 2015-05-22 2016-12-01 Fresenius Kabi Deutschland Gmbh Vitamin a for parenteral administration
JP6977231B2 (ja) 2015-07-13 2021-12-08 マラ リニューアブルズ コーポレーション C5有機炭素の微生物による代謝の増強
ITUB20152958A1 (it) 2015-08-06 2017-02-06 Eni Spa Metodo per concentrare una sospensione cellulare comprendente una biomassa mucillaginosa di lieviti oleaginosi.
KR20170119227A (ko) * 2016-04-18 2017-10-26 서울바이오시스 주식회사 공기 청정기
WO2017194683A1 (en) 2016-05-12 2017-11-16 Dsm Ip Assets B.V. Method of increasing omega-3 polyunsaturated fatty acids production in microalgae
US10851395B2 (en) 2016-06-10 2020-12-01 MARA Renewables Corporation Method of making lipids with improved cold flow properties
US11419350B2 (en) 2016-07-01 2022-08-23 Corbion Biotech, Inc. Feed ingredients comprising lysed microbial cells
BR112019000547A2 (pt) * 2016-07-13 2019-05-21 Dsm Ip Assets B.V. método para aumentar a eficiência do processo de extração de óleo
BR112019000435A2 (pt) 2016-07-13 2019-04-30 Evonik Degussa Gmbh método para separar lipídios de uma biomassa contendo lipídios lisados
WO2018069145A1 (en) 2016-10-11 2018-04-19 Fresenius Kabi Deutschland Gmbh Composition comprising epa and dha for an enhanced efficacy of anticancer agents
WO2018122057A1 (en) * 2016-12-27 2018-07-05 Evonik Degussa Gmbh Method of isolating lipids from a lipids containing biomass
EP3562925B1 (en) 2016-12-27 2021-03-10 Evonik Operations GmbH Method of isolating lipids from a lipids containing biomass
CA3072846A1 (en) 2017-08-17 2019-02-21 Evonik Operations Gmbh Enhanced production of lipids by limitation of at least two limiting nutrient sources
EP3470502A1 (en) 2017-10-13 2019-04-17 Evonik Degussa GmbH Method of separating lipids from a lysed lipids containing biomass
EA202090440A1 (ru) 2017-09-21 2020-07-17 Эвоник Оперейшенс ГмбХ Улучшенное получение липидов путем ограничения по меньшей мере двух источников лимитирующих питательных веществ
EP3527664A1 (en) 2018-02-15 2019-08-21 Evonik Degussa GmbH Method of isolating lipids from a lipids containing biomass
WO2019122030A1 (en) * 2017-12-22 2019-06-27 Dsm Ip Assets B.V. Method of separating lipids from a lysed lipids containing biomass
CN112004919A (zh) * 2018-03-30 2020-11-27 帝斯曼知识产权资产管理有限公司 通过肉汤洗涤减少乳液的方法
US20210024966A1 (en) * 2018-03-30 2021-01-28 Dsm Ip Assets B.V. Method of obtaining a microbial oil and a method of reducing emulsion by maintaining a low concentration of carbohydrate
WO2019219443A1 (en) 2018-05-15 2019-11-21 Evonik Operations Gmbh Method of isolating lipids from a lipids containing biomass with aid of hydrophobic silica
CN112384203A (zh) 2018-07-03 2021-02-19 费森尤斯卡比德国有限公司 用于胃肠外施用的脂质乳剂
FR3085962B1 (fr) * 2018-09-14 2021-06-18 Fermentalg Procede d'extracton d'une huile riche en pufa
FR3085825B1 (fr) 2018-09-14 2021-07-16 Fermentalg Huile de microorganismes riche en acide docosahexaenoique
US20220017930A1 (en) 2018-11-09 2022-01-20 Evonik Operations Gmbh Method for producing a biomass which can be easily broken down and which has an increased content of polyunsaturated fatty acids
US20220017929A1 (en) 2018-11-09 2022-01-20 Evonik Operations Gmbh Method for producing a biomass with an increased content of polyunsaturated fatty acids
MX2022007691A (es) 2019-12-20 2022-07-19 Fresenius Kabi Austria Gmbh Metodo para producir emulsiones aceite en agua.
CN111235035A (zh) * 2019-12-30 2020-06-05 嘉必优生物技术(武汉)股份有限公司 一种裂殖壶菌突变株及其用于制备二十二碳六烯酸油脂的方法和应用
FR3111912A1 (fr) 2020-06-24 2021-12-31 Fermentalg Procédé de culture de microorganismes pour l’accumulation de lipides
FR3130842A1 (fr) 2021-12-22 2023-06-23 CarbonWorks Procede de captation des phytotoxines dans un reacteur biologique
WO2023175141A1 (en) * 2022-03-18 2023-09-21 Purac Biochem B.V. Method for reducing fermentation broth viscosity
WO2023220060A1 (en) * 2022-05-11 2023-11-16 C16 Biosciences, Inc. Enzymatic lysis for extraction of bioproducts from yeast

Family Cites Families (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2753362A (en) * 1951-05-18 1956-07-03 Standard Brands Inc Process of extracting lipids from plant and animal tissue
GB808128A (en) * 1955-12-01 1959-01-28 Nat Res Dev A method of increasing the fatty contents of such micro-organisms as yeasts, bacteria and moulds
US3089821A (en) 1959-10-28 1963-05-14 Merck & Co Inc Process for the preparation of lipids
DE2056896B2 (de) * 1970-02-18 1979-12-06 Veb Schwermaschinenbau Kombinat Ernst Thaelmann Magdeburg, Ddr 3011 Magdeburg Verfahren zur gleichzeitigen Gewinnung von Fett und Protein aus pflanzlichen, ölhaltigen Rohstoffen und Zwischenprodukten
US3878232A (en) * 1970-09-28 1975-04-15 Staley Mfg Co A E Extraction process to improve the quality and yield of crude vegetable oils
US4504473A (en) * 1982-06-30 1985-03-12 Ribi Immunochem Research, Inc. Pyridine soluble extract of a microorganism
DE3248167A1 (de) * 1982-12-27 1984-06-28 Wintershall Ag, 3100 Celle Trehaloselipidtetraester
US4792418A (en) 1985-08-14 1988-12-20 Century Laboratories, Inc. Method of extraction and purification of polyunsaturated fatty acids from natural sources
JPS6244170A (ja) 1985-08-19 1987-02-26 Agency Of Ind Science & Technol モルテイエレラ属糸状菌体の超臨界流体による抽出方法
US4680314A (en) 1985-08-30 1987-07-14 Microbio Resources, Inc. Process for producing a naturally-derived carotene/oil composition by direct extraction from algae
JPH0634730B2 (ja) * 1986-06-16 1994-05-11 鐘淵化学工業株式会社 パルミトレイン酸の製造法
DK199887D0 (da) 1987-04-15 1987-04-15 Danisco Bioteknologi As Gaerstamme
FR2621327B1 (fr) 1987-10-06 1990-01-05 Commissariat Energie Atomique Procede de production et d'extraction de polysaccharides a partir d'une culture de porphyridium cruentum et dispositif pour la mise en oeuvre du procede
JPH0198494A (ja) 1987-10-09 1989-04-17 Agency Of Ind Science & Technol バイオリアクター
US5340594A (en) * 1988-09-07 1994-08-23 Omegatech Inc. Food product having high concentrations of omega-3 highly unsaturated fatty acids
US6451567B1 (en) 1988-09-07 2002-09-17 Omegatech, Inc. Fermentation process for producing long chain omega-3 fatty acids with euryhaline microorganisms
US5340742A (en) 1988-09-07 1994-08-23 Omegatech Inc. Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids
US5130242A (en) * 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
US5173409A (en) 1989-12-08 1992-12-22 Ecogen Inc. Recovery of bt endotoxin protein from lysed cell mixtures
FR2656874B1 (fr) * 1990-01-11 1992-04-03 Commissariat Energie Atomique Procede de production et d'extraction d'anti-oxydants a partir d'une culture de micro-organismes et photobioreacteur pour la mise en óoeuvre de ce procede.
US5407957A (en) * 1990-02-13 1995-04-18 Martek Corporation Production of docosahexaenoic acid by dinoflagellates
US5658767A (en) 1991-01-24 1997-08-19 Martek Corporation Arachidonic acid and methods for the production and use thereof
US6270828B1 (en) 1993-11-12 2001-08-07 Cargrill Incorporated Canola variety producing a seed with reduced glucosinolates and linolenic acid yielding an oil with low sulfur, improved sensory characteristics and increased oxidative stability
FR2686619B1 (fr) * 1992-01-28 1995-07-13 Commissariat Energie Atomique Procede de production selective de lipides poly-insatures a partir d'une culture de micro-algues du type porphyridium et cuve utilisee dans ce procede.
US5476787A (en) 1992-04-24 1995-12-19 Director-General Of Agency Of Industrial Science And Technology Method of removing nitrogen impurities from water using hydrocarbon-producing microalga
DE4219360C2 (de) * 1992-06-12 1994-07-28 Milupa Ag Verfahren zur Gewinnung von Lipiden mit einem hohen Anteil von langkettig-hochungesättigten Fettsäuren
JPH06340577A (ja) * 1993-03-24 1994-12-13 Nippon Sanso Kk 13c標識イコサペンタエン酸とその誘導体及び製造方法
JPH072724A (ja) * 1993-03-24 1995-01-06 Nippon Sanso Kk 13c標識アラキドン酸とその誘導体及び製造方法
FR2719222B1 (fr) * 1994-05-02 1996-06-21 Rocher Yves Biolog Vegetale Vésicules lipidiques, leur procédé de fabrication et leurs applications.
DE59506314D1 (de) 1994-08-16 1999-08-05 Frische Gmbh Verfahren zur gewinnung von nicht wasserlöslichen, nativen produkten aus nativen stoffgemengen mit hilfe der zentrifugalkraft
US5583019A (en) 1995-01-24 1996-12-10 Omegatech Inc. Method for production of arachidonic acid
WO1996033263A1 (fr) 1995-04-17 1996-10-24 JAPAN, represented by DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY Nouveaux micro-organismes capables de produire des acides gras hautement insatures et procede de production d'acides gras hautement insatures utilisant ces micro-organismes
JP2764572B2 (ja) * 1995-04-17 1998-06-11 工業技術院長 ドコサヘキサエン酸生産能を有する新規微生物及びそれを用いたドコサヘキサエン酸の製造方法
EP0741183B1 (fr) * 1995-05-04 1999-03-24 Societe Des Produits Nestle S.A. Procédé de fractionnement d'acides gras
GB9514649D0 (en) * 1995-07-18 1995-09-13 Zeneca Ltd Extraction of triglycerides from microorganisms
JP3985035B2 (ja) * 1995-09-14 2007-10-03 独立行政法人産業技術総合研究所 (n−6)系ドコサペンタエン酸含有油脂ならびに該油脂の製造方法および用途
US6255505B1 (en) 1996-03-28 2001-07-03 Gist-Brocades, B.V. Microbial polyunsaturated fatty acid containing oil from pasteurised biomass
EP0969086A1 (en) 1996-07-03 2000-01-05 Sagami Chemical Research Center Microorganisms producing docosahexaenoic acid and process for the production of docosahexaenoic acid
EE04063B1 (et) 1996-07-23 2003-06-16 Nagase Biochemicals, Ltd. Meetod dokosaheksaeenhappe ning dokosapentaeenhappe valmistamiseks
US5951875A (en) 1996-12-20 1999-09-14 Eastman Chemical Company Adsorptive bubble separation methods and systems for dewatering suspensions of microalgae and extracting components therefrom
ATE408701T1 (de) * 1997-03-04 2008-10-15 Suntory Ltd Verfahren zur herstellung von hochungesättigten fettsäuren und hochungesättigte fettsäuren enthaltendes lipid
DE69841382D1 (de) * 1997-05-02 2010-01-28 Dsm Ip Assets Bv Isolierung von carotenoiden kristallen aus mikrobieller biomasse
US7585645B2 (en) 1997-05-27 2009-09-08 Sembiosys Genetics Inc. Thioredoxin and thioredoxin reductase containing oil body based products
EP1905309A1 (en) 1997-05-27 2008-04-02 SemBioSys Genetics Inc. Uses of oil bodies
US6566583B1 (en) 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
JP3836231B2 (ja) * 1997-10-17 2006-10-25 日本化学飼料株式会社 ホタテガイ中腸腺から得られる高度不飽和脂肪酸含有油及びその製造方法
JP3212621B2 (ja) 1997-11-12 2001-09-25 三菱電機株式会社 エレクトロルミネッセンスライト及びそのシールド構造
JP2000041684A (ja) 1998-07-29 2000-02-15 Daicel Chem Ind Ltd 新規なd−アミノアシラーゼおよびその製造方法、並びに該d−アミノアシラーゼを利用したd−アミノ酸の製造方法
FR2782921B1 (fr) 1998-09-09 2002-09-20 Dior Christian Parfums Extrait lipidique de l'algue skeletonema, procede de preparation et utilisation dans des domaines cosmetique et pharmaceutique, notamment dermatologique
US6166231A (en) 1998-12-15 2000-12-26 Martek Biosciences Corporation Two phase extraction of oil from biomass
JP2000245492A (ja) 1999-03-02 2000-09-12 Kyowa Hakko Kogyo Co Ltd 微生物抽出脂質
US6344349B1 (en) 1999-12-06 2002-02-05 Decant Technologies Llc Process and system for electrical extraction of intracellular matter from biological matter
EP1252324B1 (en) * 2000-01-19 2010-10-20 Martek Biosciences Corporation Solventless extraction process
DE10018213A1 (de) 2000-04-12 2001-10-25 Westfalia Separator Ind Gmbh Verfahren zur Fraktionierung von öl-und lecithinhaltigen nativen Rohstoffen
DE60140352D1 (de) 2000-04-12 2009-12-17 Gea Westfalia Separator Gmbh Verfahren zur fraktionierung von öl- und polar lipid-enthaltenden rohstoffen unter verwendung von alkohol und zentrifugation
EP1178118A1 (en) 2000-08-02 2002-02-06 Dsm N.V. Isolation of microbial oils
US20060060520A1 (en) 2001-06-25 2006-03-23 Bomberger David C Systems and methods using a solvent for the removal of lipids from fluids
WO2003017945A2 (en) 2001-08-24 2003-03-06 Martek Biosciences Boulder Corporation Products containing highly unsaturated fatty acids for use by women and their children during stages of preconception, pregnancy and lactation/post-partum
US7419596B2 (en) 2001-12-12 2008-09-02 Martek Biosciences Corporation Extraction and winterization of lipids from oilseed and microbial sources
EP2266525B1 (en) 2002-05-03 2012-07-11 Martek Biosciences Corporation High quality lipids and methods for producing by enzymatic liberation from biomass
EP3111767B1 (en) 2002-06-19 2018-11-21 DSM IP Assets B.V. Microbial oil and processes for its processing
AU2004280575B8 (en) 2003-10-02 2010-05-13 Dsm Ip Assets B.V. Production of high levels of DHA in microalgae using modified amounts of chloride and potassium
AU2005217300B2 (en) 2004-03-01 2010-12-02 Suntory Holdings Limited Process for producing phospholipid containing long chain polyunsaturated fatty acid as constituent thereof and utilization of the same
JP2007534335A (ja) 2004-04-27 2007-11-29 バクスター・インターナショナル・インコーポレイテッド 攪拌タンク反応器システム
EP1597976B1 (en) 2004-05-21 2013-01-30 Nestec S.A. Use of polyol esters of fatty acids in aerated frozen confection with improved nutritional attributes
DE102004062141A1 (de) 2004-12-23 2006-07-06 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Verfahren zur Herstellung eines Rohöls aus Gemischen von Mikroorganismen und Pflanzen, das so hergestellte Öl sowie die spezifischen Verwendungen des so hergestellten und gegebenenfalls zusätzlich raffinierten Öls
DE102005003624A1 (de) 2005-01-26 2006-07-27 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Herstellung und Anwendung eines antioxidativ wirksamen Extraktes aus Crypthecodinium sp.
NZ563125A (en) 2005-06-03 2009-11-27 Mcfarlane Marketing Aust Pty L Lipid extract of mussels and method for preparation thereof
EP2447356B1 (en) 2005-06-07 2016-04-20 DSM Nutritional Products AG Eukaryotic microorganisms for producing lipids and antioxidants
MX300085B (es) 2005-07-01 2012-06-08 Martek Biosciences Corp Producto oleoso que contiene acido graso poli-insaturado y usos y produccion del mismo.
US7527734B1 (en) 2005-11-15 2009-05-05 Shepherd Samuel L Rapid non-equilibrium decompression of microorganism-containing waste streams
AU2007213506A1 (en) 2006-02-07 2007-08-16 Universitetet I Oslo Omega 3
JP5658876B2 (ja) 2006-07-05 2015-01-28 フォトンズ コーポレーション リミテッド 大規模従属栄養培養領域にて産生される超高純度epaと極性脂質
EP1887011A1 (en) 2006-08-09 2008-02-13 Thermphos Trading GmbH Alpha amino acid phosphonic acid compounds, method of preparation and use thereof
WO2008130372A2 (en) 2006-09-28 2008-10-30 Microbia, Inc. Production of sterols in oleaginous yeast and fungi
US20080083352A1 (en) 2006-10-10 2008-04-10 Ernest Peter Tovani Vehicle Table System
KR100810314B1 (ko) 2006-10-11 2008-03-04 삼성전자주식회사 휴대 단말기의 키 입력 장치
US8088614B2 (en) 2006-11-13 2012-01-03 Aurora Algae, Inc. Methods and compositions for production and purification of biofuel from plants and microalgae
US7816570B2 (en) 2006-12-01 2010-10-19 North Carolina State University Process for conversion of biomass to fuel
EP2106280A2 (en) 2006-12-22 2009-10-07 Danisco US, INC., Genencor Division Enzyme-assisted de-emulsification of aqueous lipid extracts
KR20100039846A (ko) 2007-06-14 2010-04-16 닉콜라오스 미트로포울로스 바이오연료용 조류의 성장
US20100226977A1 (en) 2007-08-29 2010-09-09 Aker Biomarine Asa Low viscosity phospholipid compositions
CN113846129A (zh) 2007-09-12 2021-12-28 帝斯曼知识产权资产管理有限公司 生物油及其制备与应用
JP4594998B2 (ja) * 2008-05-21 2010-12-08 株式会社日立製作所 エレベーターかごの速度検出装置の検査方法。
ITMI20081203A1 (it) 2008-06-30 2010-01-01 Eni Spa Procedimento per l'estrazione di acidi grassi da biomassa algale
EP2145942A1 (de) 2008-07-15 2010-01-20 Lonza Ltd. Verfahren zur Isolierung von Ölen aus Zellen und Biomasse
BRPI0917961A2 (pt) 2008-08-04 2017-04-11 Kai Bioenergy cultivo, colheita e extração contínua de óleo de culturas fotossintéticas
EP2337857B1 (en) 2008-10-02 2017-02-22 Nieves Gonzalez Ramon Microalgae extract containing 3 -polyunsaturated fatty acids and method for extracting oil from micro-organisms
US20100239712A1 (en) 2008-10-14 2010-09-23 Solazyme, Inc. Food Compositions of Microalgal Biomass
SE534278C2 (sv) 2009-02-17 2011-06-28 Alfa Laval Corp Ab Ett kontinuerligt förfarande för isolering av oljor från alger eller mikroorganismer
US9296985B2 (en) 2009-03-10 2016-03-29 Valicor, Inc. Algae biomass fractionation
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
US8476060B2 (en) 2009-04-13 2013-07-02 Board Of Regents, The University Of Texas System Process for separating lipids from a biomass
BRPI1012026A2 (pt) 2009-05-26 2018-07-17 Solazyme Inc fracionamento de biomassa microbiana contendo óleo
KR101659765B1 (ko) 2009-09-28 2016-09-27 삼성전자주식회사 다중 모드 휴대용 단말기에서 전력 소모를 줄이기 위한 장치 및 방법
US20110256268A1 (en) 2010-04-14 2011-10-20 Solazyme, Inc. Oleaginous Yeast Food Compositions
JP5911479B2 (ja) 2010-06-01 2016-04-27 ディーエスエム アイピー アセッツ ビー.ブイ. 細胞からの脂質の抽出およびそれに由来する生産物
WO2011159682A1 (en) 2010-06-14 2011-12-22 Raveendran Pottathil Methods for the production of algae derived oils
MA34468B1 (fr) 2010-07-26 2013-08-01 Sapphire Energy Inc Procédé pour récupérer des composés oléagineux à partir d'une biomasse
US9028696B2 (en) 2010-07-26 2015-05-12 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds from biomass
US8192627B2 (en) 2010-08-06 2012-06-05 Icm, Inc. Bio-oil recovery methods
US20120040428A1 (en) 2010-08-13 2012-02-16 Paul Reep Procedure for extracting of lipids from algae without cell sacrifice
US20120129244A1 (en) 2010-10-17 2012-05-24 Michael Phillip Green Systems, methods and apparatuses for dewatering, flocculating and harvesting algae cells
CN101985637B (zh) 2010-11-02 2014-05-07 嘉必优生物工程(武汉)有限公司 一种微生物油脂的提取方法
PT2450425E (pt) 2010-11-08 2014-07-24 Neste Oil Oyj Um método para a extração de lípidos a partir de biomassa
AU2012214187A1 (en) 2011-02-12 2013-05-02 Phycal, Inc. Aqueous extraction methods for high lipid microorganisms
CN107630017A (zh) 2011-03-07 2018-01-26 Dsm营养产品股份公司 工程化破囊壶菌属微生物
WO2012125611A2 (en) 2011-03-15 2012-09-20 Iowa State University Research Foundation Oil extraction from microalgae
FR2975705B1 (fr) 2011-05-27 2014-12-26 Roquette Freres Procede d'extraction du squalene a partir de microalgues
CN102433215A (zh) 2011-09-22 2012-05-02 厦门汇盛生物有限公司 一种从真菌或藻类中物理破壁提取油脂的方法
CN102388988B (zh) 2011-11-08 2013-01-23 中国农业科学院油料作物研究所 一种微生物油的分提方法
US9200236B2 (en) 2011-11-17 2015-12-01 Heliae Development, Llc Omega 7 rich compositions and methods of isolating omega 7 fatty acids
IN2014DN08554A (hu) 2012-04-16 2015-05-15 Roquette Freres
EP2867355A1 (en) 2012-06-29 2015-05-06 BP Biofuels UK Ltd. Process for separation of renewable materials from microorganisms
US11124736B2 (en) 2013-12-20 2021-09-21 Dsm Ip Assets B.V. Processes for obtaining microbial oil from microbial cells
KR102435268B1 (ko) 2013-12-20 2022-08-22 디에스엠 뉴트리셔널 프라덕츠 아게 미생물로부터 오일을 회수하는 방법
BR112016014519B1 (pt) 2013-12-20 2022-07-12 Dsm Ip Assets B.V Método de extração de lipídeos apropriados para uso na produção de biocombustíveis
CN115141859A (zh) 2013-12-20 2022-10-04 玛拉可再生能源公司 从微生物中回收油的方法
NZ721417A (en) 2013-12-20 2022-07-01 Dsm Ip Assets Bv Processes for obtaining microbial oil from microbial cells
JP2017501709A (ja) 2013-12-20 2017-01-19 ディーエスエム アイピー アセッツ ビー.ブイ. 微生物細胞から微生物油を入手する方法
JP2017500041A (ja) 2013-12-20 2017-01-05 ディーエスエム アイピー アセッツ ビー.ブイ. 微生物細胞から微生物油を入手する方法
SG11201605052XA (en) 2013-12-20 2016-07-28 Dsm Ip Assets Bv Processes for obtaining microbial oil from microbial cells
CA2954203C (en) 2014-07-07 2023-12-05 Commonwealth Scientific And Industrial Research Organisation Processes for producing industrial products from plant lipids

Also Published As

Publication number Publication date
KR101429236B1 (ko) 2014-08-12
ES2675517T3 (es) 2018-07-11
DK1252324T3 (da) 2010-12-20
MX297659B (en) 2012-03-29
NO20023449D0 (no) 2002-07-18
JP4537887B2 (ja) 2010-09-08
JP2010051328A (ja) 2010-03-11
US20170298288A1 (en) 2017-10-19
AU780619B2 (en) 2005-04-07
MXPA02007092A (es) 2003-02-24
JP2005278650A (ja) 2005-10-13
BR0107699B1 (pt) 2014-05-27
US20020001833A1 (en) 2002-01-03
US20080044876A1 (en) 2008-02-21
US20080038800A1 (en) 2008-02-14
US10329515B2 (en) 2019-06-25
JP2013099365A (ja) 2013-05-23
US20190256797A1 (en) 2019-08-22
KR101180462B1 (ko) 2012-09-06
KR20150020609A (ko) 2015-02-26
JP4020642B2 (ja) 2007-12-12
KR20120070588A (ko) 2012-06-29
CA2772540A1 (en) 2001-07-26
JP2015133969A (ja) 2015-07-27
KR100995575B1 (ko) 2010-11-19
CN101463371A (zh) 2009-06-24
JP5722536B2 (ja) 2015-05-20
JP5756137B2 (ja) 2015-07-29
IL206960A0 (en) 2010-12-30
KR20030013367A (ko) 2003-02-14
EP1252324B1 (en) 2010-10-20
PL356587A1 (en) 2004-06-28
US6750048B2 (en) 2004-06-15
NO20110858L (no) 2002-09-17
HUP0300556A3 (en) 2010-03-29
KR101591834B1 (ko) 2016-02-18
AU2014203384B2 (en) 2016-03-03
AU2019226124A1 (en) 2019-09-26
MX275361B (en) 2010-04-21
NZ520287A (en) 2004-01-30
EP2295595A1 (en) 2011-03-16
CA2397655A1 (en) 2001-07-26
MX350779B (es) 2017-09-18
WO2001053512A1 (en) 2001-07-26
US7662598B2 (en) 2010-02-16
BR0107699A (pt) 2003-01-14
US9738851B2 (en) 2017-08-22
IL150772A0 (en) 2003-02-12
US7781193B2 (en) 2010-08-24
US20140212936A1 (en) 2014-07-31
EP2302065A1 (en) 2011-03-30
KR20140079870A (ko) 2014-06-27
AU2012200890B2 (en) 2014-07-31
CN100460513C (zh) 2009-02-11
AU2005202980A1 (en) 2005-08-04
EP1252324A1 (en) 2002-10-30
ATE485385T1 (de) 2010-11-15
AU2018200956A1 (en) 2018-03-01
ES2735987T3 (es) 2019-12-23
AU2014203384A1 (en) 2014-07-10
AU2016203318A1 (en) 2016-06-09
KR20110000592A (ko) 2011-01-03
AU2005202980C1 (en) 2009-04-02
US20080044875A1 (en) 2008-02-21
KR20080007279A (ko) 2008-01-17
JP2003520046A (ja) 2003-07-02
IL150772A (en) 2010-06-16
MX232239B (es) 2005-11-18
EP2295594B1 (en) 2018-04-04
EP2295594A1 (en) 2011-03-16
KR101429238B1 (ko) 2014-08-12
AU2012200890A1 (en) 2012-03-08
IL201756A (en) 2011-06-30
ES2352001T3 (es) 2011-02-14
RU2002119551A (ru) 2004-02-20
KR20100051131A (ko) 2010-05-14
US7351558B2 (en) 2008-04-01
CA2397655C (en) 2012-06-05
KR20130032395A (ko) 2013-04-01
CZ303446B6 (cs) 2012-09-19
EP2295595B1 (en) 2019-05-01
AU2005202980B2 (en) 2008-07-10
US20040229325A1 (en) 2004-11-18
ZA200205790B (en) 2003-07-28
PT1252324E (pt) 2010-12-16
RU2336307C2 (ru) 2008-10-20
AU2963601A (en) 2001-07-31
CN1416469A (zh) 2003-05-07
DE60143287D1 (de) 2010-12-02
IL206961A (en) 2011-11-30
HK1050716A1 (en) 2003-07-04
EP1252324A4 (en) 2005-02-09
NO20023449L (no) 2002-09-17

Similar Documents

Publication Publication Date Title
HUP0300556A2 (hu) Oldószermentes extrakciós eljárás
HUP9903703A2 (hu) Eljárás dokozahexaénsav és dokozapentaénsav előállítására
BR0107832A (pt) Processo de extração sem o uso de solvente e lipìdios obtidos
WO2005063971A3 (en) Definitive endoderm
KR100204359B1 (en) Cell-free synthesis and isolation of novel gene and popyeptide
ATE407138T1 (de) Verfahren zur herstellung interferierender rna- moleküle in säugetierzellen und therapeutische anwendungen solcher moleküle
AR042320A1 (es) Procedimiento para la purificacion oxidativa de acido tereftalico
BR0313070A (pt) Métodos para preparação de um diastereÈmero desejado de uma tetraidro-beta-carbolina e para preparação de um composto
NO20051292L (no) Fremgangsmate for separasjon av intermediater som kan anvendes for fremstillingen av escitalopram.
BR0108063A (pt) Processo para epoxidação de olefinas
BR0215469A (pt) Método aperfeiçoado de produção de licopeno pela fermentação de cepas selecionadas de blakeslea trispora, formulações e usos do licopeno obtido
WO2006046076A3 (en) Applications of isolated nucleic acid fragments comprising cpg islands
ATE323777T1 (de) Verfahren zur herstellung von lysophosphatidyl- ethanolamin
EP0899321A3 (en) Process oil production
ATE469149T1 (de) Verfahren zur herstellung von cabergolin
TW200611901A (en) Method for producing 1, 3-dioxolan-4, 6-dione compound
PT711349E (pt) Genes que codificam para o complexo desidrogenase de acido alfa-cetonico de cadeia ramificada a partir de streptomyces avermitilis
DE602004011960D1 (de) Verfahren zur herstellung von polycarbonat
AU2003260506A1 (en) Method for the production of acylphosphine oxides
ATE473951T1 (de) Katalytisches verfahren zur herstellung von isolongifolen
DE60003807D1 (de) Enantiomere von mercaptolactonen und verfahren zu ihrer herstellung
WO2005020883A3 (en) Methods for the production of ansamitocins
WO1999012958A3 (de) Ampullosporin, verfahren zu dessen herstellung und dessen verwendung
DE60314904D1 (de) Verfahren zur herstellung von chinoloncarboxylat-derivaten
AR027687A1 (es) Procedimiento para preparar camptotecina

Legal Events

Date Code Title Description
FA9A Lapse of provisional patent protection due to relinquishment or protection considered relinquished