BR0215469A - Método aperfeiçoado de produção de licopeno pela fermentação de cepas selecionadas de blakeslea trispora, formulações e usos do licopeno obtido - Google Patents

Método aperfeiçoado de produção de licopeno pela fermentação de cepas selecionadas de blakeslea trispora, formulações e usos do licopeno obtido

Info

Publication number
BR0215469A
BR0215469A BR0215469-2A BR0215469A BR0215469A BR 0215469 A BR0215469 A BR 0215469A BR 0215469 A BR0215469 A BR 0215469A BR 0215469 A BR0215469 A BR 0215469A
Authority
BR
Brazil
Prior art keywords
lycopene
fermentation
formulations
blakeslea trispora
improved method
Prior art date
Application number
BR0215469-2A
Other languages
English (en)
Inventor
Ana Teresa Marcos Rodriguez
Antonio Estrella De Castro
Javier Costa Perez
Manuel Antonio Oliver Ruiz
Nieves Fraile Yecora
Juan Luis De La Fuente
Marta Rodriguez Saiz
Bruno Diez Garcia
Enrique Peiro Cezon
Angel Muñoz
Walter Cabri
Jose Luis Lopez Ortiz
Jose Luis Barredo Fuente
Original Assignee
Vitatene Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vitatene Sa filed Critical Vitatene Sa
Publication of BR0215469A publication Critical patent/BR0215469A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/40—Colouring or decolouring of foods
    • A23L5/42—Addition of dyes or pigments, e.g. in combination with optical brighteners
    • A23L5/43—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives
    • A23L5/44—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives using carotenoids or xanthophylls
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B61/00—Dyes of natural origin prepared from natural sources, e.g. vegetable sources
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"MéTODO APERFEIçOADO DE PRODUçãO DE LICOPENO PELA FERMENTAçãO DE CEPAS SELECIONADAS DE BLASKESLEA TRISPORA, FORMULAçõES E USOS DO LICOPENO OBTIDO". A presente invenção descreve uma série de métodos de obtenção de altos rendimentos de licopeno com o fungo B. trispora, bem como métodos para sua recuperação e formulação. A invenção consiste em (i) a criação de métodos para obtenção e seleção de mutantes de B. trispora que são superprodutores de licopeno, (ii) o desenvolvimento de condições aperfeiçoadas de fermentação, (iii) a definição dos processos de recuperação do licopeno a partir do micélio e (iv) a obtenção de formulações que superam os problemas de estabilidade e solubilidade em vários meios, presentes na técnica anterior. A espécie B. trispora é um fungo de grande importância industrial para a produção biotecnológica de licopeno. Na verdade, o referido processo demonstra ser competitivo com o processo sintético atualmente utilizado na indústria.
BR0215469-2A 2001-12-31 2002-12-20 Método aperfeiçoado de produção de licopeno pela fermentação de cepas selecionadas de blakeslea trispora, formulações e usos do licopeno obtido BR0215469A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200102925A ES2195758B1 (es) 2001-12-31 2001-12-31 Procedimiento mejorado de produccion de licopeno mediante la fermentacion de cepas seleccionadas de blakeslea trispora, formulaciones y usos del licopeno obtenido.
PCT/ES2002/000610 WO2003056028A1 (es) 2001-12-31 2002-12-20 Procedimiento mejorado de produccion de licopeno mediante la fermentacion de cepas seleccionadas de blakeslea trispora, formulaciones y usos del licopeno obtenido

Publications (1)

Publication Number Publication Date
BR0215469A true BR0215469A (pt) 2005-04-05

Family

ID=8499909

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0215469-2A BR0215469A (pt) 2001-12-31 2002-12-20 Método aperfeiçoado de produção de licopeno pela fermentação de cepas selecionadas de blakeslea trispora, formulações e usos do licopeno obtido

Country Status (13)

Country Link
US (1) US7799540B2 (pt)
EP (2) EP1471151B1 (pt)
JP (2) JP2005512599A (pt)
CN (1) CN1617934A (pt)
AT (1) ATE447619T1 (pt)
AU (2) AU2002361274A1 (pt)
BR (1) BR0215469A (pt)
CA (1) CA2472401C (pt)
DE (1) DE60234277D1 (pt)
ES (2) ES2195758B1 (pt)
MX (1) MXPA04006279A (pt)
RU (1) RU2296161C2 (pt)
WO (1) WO2003056028A1 (pt)

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Also Published As

Publication number Publication date
WO2003056028A1 (es) 2003-07-10
AU2008264168A1 (en) 2009-01-29
EP1471151B1 (en) 2009-11-04
ES2195758A1 (es) 2003-12-01
AU2002361274A1 (en) 2003-07-15
EP2143800B1 (en) 2013-06-19
ES2333944T3 (es) 2010-03-03
JP2005512599A (ja) 2005-05-12
ATE447619T1 (de) 2009-11-15
RU2296161C2 (ru) 2007-03-27
ES2195758B1 (es) 2005-03-01
US20050106657A1 (en) 2005-05-19
AU2008264168B2 (en) 2011-11-24
JP4960982B2 (ja) 2012-06-27
CA2472401A1 (en) 2003-07-10
MXPA04006279A (es) 2005-02-24
CA2472401C (en) 2014-02-11
DE60234277D1 (de) 2009-12-17
EP1471151A1 (en) 2004-10-27
US7799540B2 (en) 2010-09-21
RU2004123627A (ru) 2005-04-10
JP2009171973A (ja) 2009-08-06
CN1617934A (zh) 2005-05-18
EP2143800A1 (en) 2010-01-13

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