BR0107699A - Processo de extração sem o uso de solventes e lipìdeos obtidos - Google Patents

Processo de extração sem o uso de solventes e lipìdeos obtidos

Info

Publication number
BR0107699A
BR0107699A BR0107699-0A BR0107699A BR0107699A BR 0107699 A BR0107699 A BR 0107699A BR 0107699 A BR0107699 A BR 0107699A BR 0107699 A BR0107699 A BR 0107699A
Authority
BR
Brazil
Prior art keywords
lipid
layer
extraction process
heavy
organic solvent
Prior art date
Application number
BR0107699-0A
Other languages
English (en)
Other versions
BR0107699B1 (pt
Inventor
George T Veeder Iii
Brian S Engelhardt
Swithin Patrick Adu-Peasah
Craig M Ruecker
Original Assignee
Omegatech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22647287&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0107699(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Omegatech Inc filed Critical Omegatech Inc
Publication of BR0107699A publication Critical patent/BR0107699A/pt
Publication of BR0107699B1 publication Critical patent/BR0107699B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11BPRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00Refining fats or fatty oils
    • C11B3/006Refining fats or fatty oils by extraction
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11BPRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00Production of fats or fatty oils from raw materials
    • C11B1/02Pretreatment
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11BPRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00Refining fats or fatty oils
    • C11B3/001Refining fats or fatty oils by a combination of two or more of the means hereafter
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06Lysis of microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P25/00Preparation of compounds containing alloxazine or isoalloxazine nucleus, e.g. riboflavin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432Eicosapentaenoic acids [EPA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434Docosahexenoic acids [DHA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6463Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

"PROCESSO DE EXTRAçãO SEM O USO DE SOLVENTE E LIPìDIOS OBTIDOS". O presente resumo refere-se a uma patente de invenção para um processo de extração de lipídios de microorganismos, sem o uso de qualquer volume significativo de solvente orgânico não-polar, compreendendo, substancialmente: (a) o lisado de células de microorganismos para a produção de uma mistura celular lisada; (b) o tratamento da mistura celular lisada para produzir uma mistura de fase separada compreendendo uma camada pesada e uma camada leve, onde a referida camada pesada compreende uma solução aquosa e a referida camada leve compreende o referido lipídio; (c) a separação da referida camada pesada da referida camada; e (d) a obtenção do referido lipídio a partir da camada leve; e o lipídio obtido sendo substancialmente derivado de microorganismos com menos que 0,2 ppm de solvente orgânico residual não-polar.
BRPI0107699-0B1A 2000-01-19 2001-01-19 Processo de extração livre de solvente BR0107699B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17712500P 2000-01-19 2000-01-19
US60/177,125 2000-01-19
PCT/US2001/001806 WO2001053512A1 (en) 2000-01-19 2001-01-19 Solventless extraction process

Publications (2)

Publication Number Publication Date
BR0107699A true BR0107699A (pt) 2003-01-14
BR0107699B1 BR0107699B1 (pt) 2014-05-27

Family

ID=22647287

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0107699-0B1A BR0107699B1 (pt) 2000-01-19 2001-01-19 Processo de extração livre de solvente

Country Status (24)

Country Link
US (8) US6750048B2 (pt)
EP (4) EP2302065A1 (pt)
JP (5) JP4020642B2 (pt)
KR (8) KR20140079870A (pt)
CN (1) CN100460513C (pt)
AT (1) ATE485385T1 (pt)
AU (7) AU780619B2 (pt)
BR (1) BR0107699B1 (pt)
CA (2) CA2397655C (pt)
CZ (1) CZ303446B6 (pt)
DE (1) DE60143287D1 (pt)
DK (1) DK1252324T3 (pt)
ES (3) ES2735987T3 (pt)
HK (1) HK1050716A1 (pt)
HU (1) HUP0300556A3 (pt)
IL (5) IL150772A0 (pt)
MX (4) MX350779B (pt)
NO (2) NO20023449L (pt)
NZ (1) NZ520287A (pt)
PL (1) PL356587A1 (pt)
PT (1) PT1252324E (pt)
RU (1) RU2336307C2 (pt)
WO (1) WO2001053512A1 (pt)
ZA (1) ZA200205790B (pt)

Families Citing this family (202)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7078051B1 (en) 1998-08-11 2006-07-18 Natural Asa Conjugated linoleic acid alkyl esters in feedstuffs and food
US7776353B1 (en) 1998-03-17 2010-08-17 Aker Biomarine Asa Conjugated linoleic acid compositions
ATE350028T1 (de) 1998-03-17 2007-01-15 Natural Asa Konjugierte linolsäurezusammensetzung
US7101914B2 (en) 1998-05-04 2006-09-05 Natural Asa Isomer enriched conjugated linoleic acid compositions
KR20140079870A (ko) 2000-01-19 2014-06-27 마텍 바이오싸이언스스 코포레이션 무용매 추출 방법
WO2001077271A2 (en) * 2000-04-06 2001-10-18 Conlinco, Inc. Conjugated linoleic acid compositions
EP1274320A2 (en) 2000-04-18 2003-01-15 Natural AS Conjugated linoleic acid powder
EP1178118A1 (en) 2000-08-02 2002-02-06 Dsm N.V. Isolation of microbial oils
US6677470B2 (en) 2001-11-20 2004-01-13 Natural Asa Functional acylglycerides
US7419596B2 (en) * 2001-12-12 2008-09-02 Martek Biosciences Corporation Extraction and winterization of lipids from oilseed and microbial sources
EP2921155B1 (en) 2002-05-03 2020-01-08 DSM IP Assets B.V. Methods for producing high-quality lipids by enzymatic liberation from biomass
US6743931B2 (en) 2002-09-24 2004-06-01 Natural Asa Conjugated linoleic acid compositions
CN103834699A (zh) 2003-10-02 2014-06-04 Dsmip资产公司 使用改进量的氯和钾在微藻类中产生高水平的dha
CA2553671A1 (en) 2004-01-26 2005-08-11 Martek Biosciences Corporation Method for the separation of phospholipids from phospholipid-containing materials
EA016258B1 (ru) 2005-03-18 2012-03-30 Микробиа, Инк. Рекомбинантные грибы, продуцирующие каротиноиды, и способы их применения
WO2006124598A2 (en) * 2005-05-12 2006-11-23 Martek Biosciences Corporation Biomass hydrolysate and uses and production thereof
PL2447356T3 (pl) 2005-06-07 2016-10-31 Mikroorganizmy eukariotyczne do wytwarzania lipidów i przeciwutleniaczy
EP1903883A4 (en) 2005-07-01 2010-06-23 Martek Biosciences Corp OIL PRODUCT CONTAINING MULTIPLE UNSATURATED FATTY ACIDS AND ITS USES AND MANUFACTURING
US8298548B2 (en) 2007-07-18 2012-10-30 Solazyme, Inc. Compositions for improving the health and appearance of skin
US8277849B2 (en) 2006-01-19 2012-10-02 Solazyme, Inc. Microalgae-derived compositions for improving the health and appearance of skin
US20100242345A1 (en) * 2006-05-19 2010-09-30 LS9, Inc Production of fatty acids & derivatives thereof
US8110670B2 (en) 2006-05-19 2012-02-07 Ls9, Inc. Enhanced production of fatty acid derivatives
EP2044208A4 (en) * 2006-07-05 2012-02-22 Photonz Corp Ltd PRODUCTION OF EPA AND ULTRA PURE POLAR LIPIDS FROM A BROADLY HETERATROPHE CULTURE
JP4854418B2 (ja) * 2006-07-28 2012-01-18 花王株式会社 ドデカヒドロ−3a,6,6,9a−テトラメチルナフト[2,1−b]フラン原料の製造方法
MX2009001346A (es) * 2006-08-01 2009-04-17 Ocean Nutrition Canada Ltd Microbios productores de aceite y metodos de modificacion de los mismos.
WO2008042338A2 (en) 2006-09-28 2008-04-10 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
US8262776B2 (en) * 2006-10-13 2012-09-11 General Atomics Photosynthetic carbon dioxide sequestration and pollution abatement
US8088614B2 (en) * 2006-11-13 2012-01-03 Aurora Algae, Inc. Methods and compositions for production and purification of biofuel from plants and microalgae
UA103595C2 (uk) * 2007-04-03 2013-11-11 Е. І. Дю Пон Де Немур Енд Компані Мультизими і їх застосування в отриманні поліненасичених жирних кислот
MY154965A (en) 2007-06-01 2015-08-28 Solazyme Inc Production of oil in microorganisms
WO2008155410A1 (en) * 2007-06-21 2008-12-24 Novozymes A/S Production of lipids containing poly-unsaturated fatty acids
JP2010532418A (ja) * 2007-06-29 2010-10-07 マーテック バイオサイエンシーズ コーポレーション 多価不飽和脂肪酸のエステルの製造方法および精製方法
EP2198038B1 (en) 2007-09-12 2018-03-14 DSM IP Assets B.V. Method for producing biological oil using a nonsterile fermentor
AU2008304180B2 (en) * 2007-09-27 2014-02-27 Genomatica, Inc. Reduction of the toxic effect of impurities from raw materials by extractive fermentation
US20100010088A1 (en) * 2007-11-01 2010-01-14 Wake Forest University School Of Medicine Compositions and Methods for Prevention and Treatment of Mammalian Diseases
US8343753B2 (en) 2007-11-01 2013-01-01 Wake Forest University School Of Medicine Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
EP2297326A4 (en) 2008-06-06 2011-11-16 Aurora Biofuels Inc VCP-BASED VECTORS FOR THE TRANSFORMATION OF ALGAE CELLS
US20100022393A1 (en) * 2008-07-24 2010-01-28 Bertrand Vick Glyphosate applications in aquaculture
US20100077654A1 (en) * 2008-09-23 2010-04-01 LiveFuels, Inc. Systems and methods for producing biofuels from algae
US20100236137A1 (en) * 2008-09-23 2010-09-23 LiveFuels, Inc. Systems and methods for producing eicosapentaenoic acid and docosahexaenoic acid from algae
CN104770424A (zh) * 2008-10-14 2015-07-15 索拉兹米公司 微藻生物质的食品组合物
US20100297325A1 (en) * 2008-10-14 2010-11-25 Solazyme, Inc. Egg Products Containing Microalgae
US20100297323A1 (en) * 2008-10-14 2010-11-25 Solazyme, Inc. Gluten-free Foods Containing Microalgae
US9896642B2 (en) 2008-10-14 2018-02-20 Corbion Biotech, Inc. Methods of microbial oil extraction and separation
US20100303957A1 (en) * 2008-10-14 2010-12-02 Solazyme, Inc. Edible Oil and Processes for Its Production from Microalgae
US20100303989A1 (en) * 2008-10-14 2010-12-02 Solazyme, Inc. Microalgal Flour
US8927522B2 (en) 2008-10-14 2015-01-06 Solazyme, Inc. Microalgal polysaccharide compositions
US20100303961A1 (en) * 2008-10-14 2010-12-02 Solazyme, Inc. Methods of Inducing Satiety
US20100303990A1 (en) * 2008-10-14 2010-12-02 Solazyme, Inc. High Protein and High Fiber Algal Food Materials
US20100297331A1 (en) * 2008-10-14 2010-11-25 Solazyme, Inc. Reduced Fat Foods Containing High-Lipid Microalgae with Improved Sensory Properties
US20100297295A1 (en) * 2008-10-14 2010-11-25 Solazyme, Inc. Microalgae-Based Beverages
US8809037B2 (en) 2008-10-24 2014-08-19 Bioprocessh20 Llc Systems, apparatuses and methods for treating wastewater
US8557249B2 (en) 2008-11-07 2013-10-15 Solazyme, Inc. Cosmetic compositions comprising microalgal components
WO2010059598A1 (en) * 2008-11-18 2010-05-27 LiveFuels, Inc. Methods for producing fish with high lipid content
JP5859311B2 (ja) 2008-11-28 2016-02-10 ソラザイム, インコーポレイテッドSolazyme Inc 組み換え従属栄養微生物における、用途に応じた油の生産
WO2010077694A1 (en) * 2008-12-08 2010-07-08 Sapphire Energy, Inc. Removal of nitrogen from a chlorophyll or pheophytin containing biomass
US8940340B2 (en) * 2009-01-22 2015-01-27 Aurora Algae, Inc. Systems and methods for maintaining the dominance of Nannochloropsis in an algae cultivation system
CA2751275A1 (en) 2009-02-02 2010-08-05 Martek Biosciences Corporation Use of docosahexaenoic acid in treating mild cognitive impairment
US8143051B2 (en) * 2009-02-04 2012-03-27 Aurora Algae, Inc. Systems and methods for maintaining the dominance and increasing the biomass production of nannochloropsis in an algae cultivation system
SE534278C2 (sv) * 2009-02-17 2011-06-28 Alfa Laval Corp Ab Ett kontinuerligt förfarande för isolering av oljor från alger eller mikroorganismer
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
SG174383A1 (en) 2009-03-19 2011-11-28 Martek Biosciences Corp Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
US8476060B2 (en) * 2009-04-13 2013-07-02 Board Of Regents, The University Of Texas System Process for separating lipids from a biomass
US8753851B2 (en) 2009-04-17 2014-06-17 LiveFuels, Inc. Systems and methods for culturing algae with bivalves
US20100297749A1 (en) * 2009-04-21 2010-11-25 Sapphire Energy, Inc. Methods and systems for biofuel production
WO2010124125A2 (en) * 2009-04-22 2010-10-28 Robert Fulton Fluidizable algae-based powdered fuel and methods for making and using same
WO2010126891A1 (en) 2009-04-27 2010-11-04 Ls9, Inc. Production of fatty acid esters
US9187778B2 (en) 2009-05-04 2015-11-17 Aurora Algae, Inc. Efficient light harvesting
BRPI1012026A2 (pt) 2009-05-26 2018-07-17 Solazyme Inc fracionamento de biomassa microbiana contendo óleo
US8809046B2 (en) 2011-04-28 2014-08-19 Aurora Algae, Inc. Algal elongases
US9029137B2 (en) 2009-06-08 2015-05-12 Aurora Algae, Inc. ACP promoter
US8865468B2 (en) * 2009-10-19 2014-10-21 Aurora Algae, Inc. Homologous recombination in an algal nuclear genome
US8865452B2 (en) * 2009-06-15 2014-10-21 Aurora Algae, Inc. Systems and methods for extracting lipids from wet algal biomass
US8769867B2 (en) * 2009-06-16 2014-07-08 Aurora Algae, Inc. Systems, methods, and media for circulating fluid in an algae cultivation pond
US9101942B2 (en) * 2009-06-16 2015-08-11 Aurora Algae, Inc. Clarification of suspensions
US8747930B2 (en) * 2009-06-29 2014-06-10 Aurora Algae, Inc. Siliceous particles
US20100325948A1 (en) * 2009-06-29 2010-12-30 Mehran Parsheh Systems, methods, and media for circulating and carbonating fluid in an algae cultivation pond
CN101585759B (zh) * 2009-07-08 2012-05-23 内蒙古金达威药业有限公司 从双鞭甲藻发酵液中提取dha不饱和脂肪酸的方法
US20110177061A1 (en) 2009-07-10 2011-07-21 Martek Biosciences Corporation Methods of treating and preventing neurological disorders using docosahexaenoic acid
US8709765B2 (en) * 2009-07-20 2014-04-29 Aurora Algae, Inc. Manipulation of an alternative respiratory pathway in photo-autotrophs
WO2011041710A2 (en) 2009-10-01 2011-04-07 Martek Biosciences Corporation Docosahexaenoic acid gel caps
US8765983B2 (en) * 2009-10-30 2014-07-01 Aurora Algae, Inc. Systems and methods for extracting lipids from and dehydrating wet algal biomass
US8748160B2 (en) * 2009-12-04 2014-06-10 Aurora Alage, Inc. Backward-facing step
CN102906270B (zh) * 2009-12-28 2016-06-22 Dsmip资产公司 在木糖上生长的重组破囊壶菌和其组合物、制备方法及用途
US20110195449A1 (en) 2009-12-28 2011-08-11 Martek Biosciences Corporation Recombinant Thraustochytrids that Grow on Sucrose, and Compositions, Methods of Making, and Uses Thereof
CN102884201B (zh) * 2010-01-19 2016-04-13 帝斯曼知识产权资产管理有限公司 生产二十碳五烯酸的微生物、脂肪酸组成物及其制作方法与用途
US8303818B2 (en) * 2010-06-24 2012-11-06 Streamline Automation, Llc Method and apparatus using an active ionic liquid for algae biofuel harvest and extraction
US8115022B2 (en) 2010-04-06 2012-02-14 Heliae Development, Llc Methods of producing biofuels, chlorophylls and carotenoids
WO2011127127A2 (en) 2010-04-06 2011-10-13 Arizona Board Of Regents For And On Behalf Of Arizona State University Extraction with fractionation of oil and co-products from oleaginous material
US8211309B2 (en) 2010-04-06 2012-07-03 Heliae Development, Llc Extraction of proteins by a two solvent method
MX2012011562A (es) 2010-04-06 2013-04-03 Heliae Dev Llc Metodo de y sistemas para producir biocombustibles.
US8308951B1 (en) 2010-04-06 2012-11-13 Heliae Development, Llc Extraction of proteins by a two solvent method
US8273248B1 (en) 2010-04-06 2012-09-25 Heliae Development, Llc Extraction of neutral lipids by a two solvent method
US8475660B2 (en) 2010-04-06 2013-07-02 Heliae Development, Llc Extraction of polar lipids by a two solvent method
US8313648B2 (en) 2010-04-06 2012-11-20 Heliae Development, Llc Methods of and systems for producing biofuels from algal oil
US8211308B2 (en) 2010-04-06 2012-07-03 Heliae Development, Llc Extraction of polar lipids by a two solvent method
US8202425B2 (en) 2010-04-06 2012-06-19 Heliae Development, Llc Extraction of neutral lipids by a two solvent method
US10125331B2 (en) * 2010-04-29 2018-11-13 Advanced Energy Development Renewable oil refining processes
CN106135460B (zh) 2010-05-28 2020-07-24 柯碧恩生物技术公司 包含特制油的食品组合物
JP5911479B2 (ja) 2010-06-01 2016-04-27 ディーエスエム アイピー アセッツ ビー.ブイ. 細胞からの脂質の抽出およびそれに由来する生産物
NL2004832C2 (en) * 2010-06-07 2011-12-08 Evodos B V Separating biomass from an aqueous medium.
US9023625B2 (en) 2010-06-14 2015-05-05 Io-Mega Holding Corporation Methods for production of algae derived oils
US9028696B2 (en) 2010-07-26 2015-05-12 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds from biomass
US8906236B2 (en) 2010-07-26 2014-12-09 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds and nutrients from biomass
EP2598641B1 (en) 2010-07-26 2014-05-21 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds from biomass
BR112013006493A2 (pt) 2010-09-21 2016-07-26 Shell Int Research processo para separar uma mistura contendo um óleo microbiano e uma substância microbiana
SG190154A1 (en) 2010-11-03 2013-06-28 Solazyme Inc Microbial oils with lowered pour points, dielectric fluids produced therefrom, and related methods
US20120329138A1 (en) 2010-12-23 2012-12-27 Shell Oil Company Process for separation of a mixture containing a microbial substance and a liquid
US8722359B2 (en) 2011-01-21 2014-05-13 Aurora Algae, Inc. Genes for enhanced lipid metabolism for accumulation of lipids
CN102617431B (zh) * 2011-01-28 2013-09-25 天津滨海索尔特生物技术中心有限公司 用无机碱提取盐藻中的β-胡萝卜素的方法
CN103827307A (zh) 2011-02-02 2014-05-28 索拉兹米公司 产自重组产油微生物的定制油
CA2827447A1 (en) * 2011-02-16 2012-08-23 Solix Biosystems, Inc. Compositions and methods for leach extraction of microorganisms
US8926844B2 (en) 2011-03-29 2015-01-06 Aurora Algae, Inc. Systems and methods for processing algae cultivation fluid
US8569530B2 (en) 2011-04-01 2013-10-29 Aurora Algae, Inc. Conversion of saponifiable lipids into fatty esters
US8440805B2 (en) 2011-04-28 2013-05-14 Aurora Algae, Inc. Algal desaturases
US8752329B2 (en) 2011-04-29 2014-06-17 Aurora Algae, Inc. Optimization of circulation of fluid in an algae cultivation pond
BR112013028621A2 (pt) 2011-05-06 2016-11-29 Solazyme Inc "microalgas oleaginosas recombinantes, método para produzir biomassa de microalga ou um produto produzido da biomassa, e método para produzir uma composição lipídica de microalga".
US9487716B2 (en) 2011-05-06 2016-11-08 LiveFuels, Inc. Sourcing phosphorus and other nutrients from the ocean via ocean thermal energy conversion systems
US20140099684A1 (en) * 2011-05-26 2014-04-10 Council Of Scientific & Industrial Research Engine worthy fatty acid methyl ester (biodiesel) from naturally occuring marine microalgal mats and marine microalgae cultured in open salt pans together with value addition of co-products
FR2975705B1 (fr) * 2011-05-27 2014-12-26 Roquette Freres Procede d'extraction du squalene a partir de microalgues
US8365462B2 (en) 2011-05-31 2013-02-05 Heliae Development, Llc V-Trough photobioreactor systems
USD661164S1 (en) 2011-06-10 2012-06-05 Heliae Development, Llc Aquaculture vessel
USD682637S1 (en) 2011-06-10 2013-05-21 Heliae Development, Llc Aquaculture vessel
USD679965S1 (en) 2011-06-10 2013-04-16 Heliae Development, Llc Aquaculture vessel
MY169454A (en) 2011-07-21 2019-04-11 Dsm Ip Assets Bv Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
MX342216B (es) 2011-07-21 2016-09-20 Dsm Ip Assets Bv Composiciones de acidos grasos.
WO2013024174A1 (en) 2011-08-18 2013-02-21 Dsm Ip Assets B.V. Dha triglyceride, dha free fatty acid, and dha ethyl ester emulsions, and methods of treating spinal cord injury
MX2014005356A (es) 2011-11-01 2014-07-09 Dsm Ip Assets Bv Aceite oxidativamente estable que contiene acidos grasos poliinsaturados.
WO2013075116A2 (en) 2011-11-17 2013-05-23 Heliae Development, Llc Omega 7 rich compositions and methods of isolating omega 7 fatty acids
CN103131529B (zh) * 2011-11-23 2016-02-24 丰益(上海)生物技术研发中心有限公司 一种提取微生物油脂的方法
AU2013249172C1 (en) 2012-04-18 2017-08-10 Corbion Biotech, Inc. Tailored oils
CN103421595A (zh) * 2012-05-25 2013-12-04 丰益(上海)生物技术研发中心有限公司 一种提取微生物油脂的方法
EP2867355A1 (en) 2012-06-29 2015-05-06 BP Biofuels UK Ltd. Process for separation of renewable materials from microorganisms
CN103589503B (zh) * 2012-08-13 2015-09-30 丰益(上海)生物技术研发中心有限公司 一种高效提取微生物油脂的方法
KR101470078B1 (ko) * 2012-08-21 2014-12-08 현대자동차주식회사 이산화탄소 포집ㆍ고정ㆍ전환을 통한 온실가스 감축 및 부가가치화 방법
US10098371B2 (en) 2013-01-28 2018-10-16 Solazyme Roquette Nutritionals, LLC Microalgal flour
US9816079B2 (en) 2013-01-29 2017-11-14 Terravia Holdings, Inc. Variant thioesterases and methods of use
US9567615B2 (en) 2013-01-29 2017-02-14 Terravia Holdings, Inc. Variant thioesterases and methods of use
EP2953480B1 (de) * 2013-02-05 2020-06-03 Evonik Operations GmbH Verbesserung der bioverfügbarkeit von wertstoffen aus mikroorganismen
EP2762009A1 (de) * 2013-02-05 2014-08-06 Evonik Industries AG Verbesserung der Bioverfügbarkeit von Wertstoffen aus Mikroorganismen
WO2014141098A1 (en) 2013-03-13 2014-09-18 Dsm Nutritional Products Ag Engineering microorganisms
US9266973B2 (en) 2013-03-15 2016-02-23 Aurora Algae, Inc. Systems and methods for utilizing and recovering chitosan to process biological material
US9783836B2 (en) 2013-03-15 2017-10-10 Terravia Holdings, Inc. Thioesterases and cells for production of tailored oils
US9290749B2 (en) 2013-03-15 2016-03-22 Solazyme, Inc. Thioesterases and cells for production of tailored oils
US9597280B2 (en) 2013-05-15 2017-03-21 Terravia Holdings, Inc. Cosmetic compositions comprising microalgal oil
EP2826384A1 (de) 2013-07-16 2015-01-21 Evonik Industries AG Verfahren zur Trocknung von Biomasse
FR3009619B1 (fr) 2013-08-07 2017-12-29 Roquette Freres Compositions de biomasse de microalgues riches en proteines de qualite sensorielle optimisee
CA2925527A1 (en) 2013-10-04 2015-04-09 Solazyme, Inc. Tailored oils
KR102143001B1 (ko) * 2013-11-01 2020-08-11 에스케이이노베이션 주식회사 초음속 분산기를 이용한 유질 미생물 파쇄 공정 및 이를 이용한 바이오 오일의 제조방법
CN105829539B (zh) * 2013-12-20 2023-11-10 帝斯曼营养品股份公司 从微生物中回收油的方法
AR098893A1 (es) 2013-12-20 2016-06-22 Dsm Ip Assets Bv Proceso para obtener aceite microbiano a partir de células microbianas
PT2958982T (pt) 2013-12-20 2019-12-19 Mara Renewables Corp Métodos de recuperação de óleo a partir de microrganismos
SG11201605009RA (en) 2013-12-20 2016-07-28 Dsm Ip Assets Bv Processes for obtaining microbial oil from microbial cells
JP6705581B2 (ja) 2013-12-20 2020-06-03 ディーエスエム アイピー アセッツ ビー.ブイ.Dsm Ip Assets B.V. 微生物細胞から微生物油を入手するための方法
KR102435265B1 (ko) * 2013-12-20 2022-08-22 디에스엠 아이피 어셋츠 비.브이. 미생물 세포로부터의 미생물 오일의 수득 방법
KR102552228B1 (ko) 2013-12-20 2023-07-05 디에스엠 아이피 어셋츠 비.브이. 미생물 세포로부터의 미생물 오일의 수득 방법
EP3620517A3 (en) 2014-07-10 2020-07-29 Corbion Biotech, Inc. Ketoacyl acp synthase genes and uses thereof
CN107087416A (zh) 2014-07-24 2017-08-22 泰拉瑞亚控股公司 变体硫酯酶及使用方法
EP3194582A2 (en) 2014-09-18 2017-07-26 TerraVia Holdings, Inc. Acyl-acp thioesterases and mutants thereof
ES2870093T3 (es) 2014-10-02 2021-10-26 Evonik Operations Gmbh Biomasa que contiene PUFA con estabilidad celular elevada y su empleo para la producción de piensos
CN106793803B (zh) 2014-10-02 2021-03-09 赢创运营有限公司 通过挤压含pufa的生物质来制备含pufa的饲料的方法
CN106793798A (zh) 2014-10-02 2017-05-31 赢创德固赛有限公司 具有高抗磨损性和高水稳定性的含pufa的饲料
CN106793799B (zh) 2014-10-02 2021-05-14 赢创运营有限公司 用于养殖动物的方法
CN107106628B (zh) 2014-12-22 2021-01-12 荷兰联合利华有限公司 毛发组合物
KR20160096478A (ko) * 2015-02-05 2016-08-16 주식회사 이코원 탄소 발열 모듈 및 이를 이용한 탄소 발열 튀김기
AR104042A1 (es) 2015-03-26 2017-06-21 Mara Renewables Corp Producción de alta densidad de biomasa y aceite utilizando glicerol en bruto
CA2971786A1 (en) 2015-03-31 2016-10-06 Fresenius Kabi Deutschland Gmbh Emulsions for parenteral administration
US20160298104A1 (en) * 2015-04-07 2016-10-13 Decant Treatment Systems, Llc Method for electrical treatment of fluid medium containing biological matter and a system for its implementation
WO2016188876A1 (en) 2015-05-22 2016-12-01 Fresenius Kabi Deutschland Gmbh Vitamin a for parenteral administration
CN107750155A (zh) 2015-05-22 2018-03-02 费森尤斯卡比德国有限公司 用于肠胃外给药的维生素a
US9951326B2 (en) 2015-07-13 2018-04-24 MARA Renewables Corporation Enhancing microbial metabolism of C5 organic carbon
ITUB20152958A1 (it) 2015-08-06 2017-02-06 Eni Spa Metodo per concentrare una sospensione cellulare comprendente una biomassa mucillaginosa di lieviti oleaginosi.
KR20170119227A (ko) * 2016-04-18 2017-10-26 서울바이오시스 주식회사 공기 청정기
US11987819B2 (en) 2016-05-12 2024-05-21 Dsm Ip Assets B.V. Method of increasing omega-3 polyunsaturated fatty acids production in microalgae
US10851395B2 (en) 2016-06-10 2020-12-01 MARA Renewables Corporation Method of making lipids with improved cold flow properties
US11419350B2 (en) 2016-07-01 2022-08-23 Corbion Biotech, Inc. Feed ingredients comprising lysed microbial cells
EP3485027A1 (en) * 2016-07-13 2019-05-22 DSM IP Assets B.V. Method for extracting a microbial oil comprising polyunsaturated fatty acids from a fermentation broth containing oleaginous microorganisms
JP6998935B2 (ja) 2016-07-13 2022-01-18 エボニック オペレーションズ ゲーエムベーハー 溶解された脂質含有バイオマスから脂質を分離する方法
WO2018069145A1 (en) 2016-10-11 2018-04-19 Fresenius Kabi Deutschland Gmbh Composition comprising epa and dha for an enhanced efficacy of anticancer agents
WO2018122057A1 (en) * 2016-12-27 2018-07-05 Evonik Degussa Gmbh Method of isolating lipids from a lipids containing biomass
CA3048289C (en) * 2016-12-27 2023-09-26 Evonik Degussa Gmbh Method of isolating lipids from a lipids containing biomass
CN111356767A (zh) 2017-08-17 2020-06-30 赢创运营有限公司 通过限制至少两种限制性营养源增强脂质的产生
EP3470502A1 (en) * 2017-10-13 2019-04-17 Evonik Degussa GmbH Method of separating lipids from a lysed lipids containing biomass
EA202090440A1 (ru) 2017-09-21 2020-07-17 Эвоник Оперейшенс ГмбХ Улучшенное получение липидов путем ограничения по меньшей мере двух источников лимитирующих питательных веществ
EP3527664A1 (en) 2018-02-15 2019-08-21 Evonik Degussa GmbH Method of isolating lipids from a lipids containing biomass
WO2019122030A1 (en) * 2017-12-22 2019-06-27 Dsm Ip Assets B.V. Method of separating lipids from a lysed lipids containing biomass
CN112004919A (zh) * 2018-03-30 2020-11-27 帝斯曼知识产权资产管理有限公司 通过肉汤洗涤减少乳液的方法
CN112004935B (zh) * 2018-03-30 2024-05-14 帝斯曼知识产权资产管理有限公司 获得微生物油的方法和通过维持低的碳水化合物浓度来减少乳液的方法
US11976253B2 (en) 2018-05-15 2024-05-07 Evonik Operations Gmbh Method of isolating lipids from a lysed lipids containing biomass by emulsion inversion
EP3794097A1 (en) 2018-05-15 2021-03-24 Evonik Operations GmbH Method of isolating lipids from a lipids containing biomass with aid of hydrophobic silica
CA3102324A1 (en) 2018-07-03 2020-01-09 Fresenius Kabi Deutschland Gmbh Lipid emulsion for parenteral administration
FR3085825B1 (fr) 2018-09-14 2021-07-16 Fermentalg Huile de microorganismes riche en acide docosahexaenoique
FR3085962B1 (fr) 2018-09-14 2021-06-18 Fermentalg Procede d'extracton d'une huile riche en pufa
CN112955564A (zh) * 2018-11-09 2021-06-11 赢创运营有限公司 用于生产可被容易破碎并具有增加的多不饱和脂肪酸含量的生物质的方法
CA3118527A1 (en) 2018-11-09 2020-05-14 Evonik Operations Gmbh Method for producing a biomass with an increased content of polyunsaturated fatty acids
WO2021123117A1 (de) 2019-12-20 2021-06-24 Fresenius Kabi Austria Gmbh Verfahren zur herstellung von öl-in-wasser-emulsionen
CN111235035A (zh) * 2019-12-30 2020-06-05 嘉必优生物技术(武汉)股份有限公司 一种裂殖壶菌突变株及其用于制备二十二碳六烯酸油脂的方法和应用
FR3111912A1 (fr) 2020-06-24 2021-12-31 Fermentalg Procédé de culture de microorganismes pour l’accumulation de lipides
FR3130842A1 (fr) 2021-12-22 2023-06-23 CarbonWorks Procede de captation des phytotoxines dans un reacteur biologique
WO2023175141A1 (en) * 2022-03-18 2023-09-21 Purac Biochem B.V. Method for reducing fermentation broth viscosity
WO2023220060A1 (en) * 2022-05-11 2023-11-16 C16 Biosciences, Inc. Enzymatic lysis for extraction of bioproducts from yeast
WO2024119170A2 (en) 2022-12-02 2024-06-06 Dsm Ip Assets B.V. Fermentatively-produced retinoid containing compositions, and the methdos of making and using the same

Family Cites Families (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2753362A (en) * 1951-05-18 1956-07-03 Standard Brands Inc Process of extracting lipids from plant and animal tissue
GB808128A (en) * 1955-12-01 1959-01-28 Nat Res Dev A method of increasing the fatty contents of such micro-organisms as yeasts, bacteria and moulds
US3089821A (en) 1959-10-28 1963-05-14 Merck & Co Inc Process for the preparation of lipids
DE2056896B2 (de) * 1970-02-18 1979-12-06 Veb Schwermaschinenbau Kombinat Ernst Thaelmann Magdeburg, Ddr 3011 Magdeburg Verfahren zur gleichzeitigen Gewinnung von Fett und Protein aus pflanzlichen, ölhaltigen Rohstoffen und Zwischenprodukten
US3878232A (en) * 1970-09-28 1975-04-15 Staley Mfg Co A E Extraction process to improve the quality and yield of crude vegetable oils
US4504473A (en) * 1982-06-30 1985-03-12 Ribi Immunochem Research, Inc. Pyridine soluble extract of a microorganism
DE3248167A1 (de) * 1982-12-27 1984-06-28 Wintershall Ag, 3100 Celle Trehaloselipidtetraester
US4792418A (en) 1985-08-14 1988-12-20 Century Laboratories, Inc. Method of extraction and purification of polyunsaturated fatty acids from natural sources
JPS6244170A (ja) 1985-08-19 1987-02-26 Agency Of Ind Science & Technol モルテイエレラ属糸状菌体の超臨界流体による抽出方法
US4680314A (en) 1985-08-30 1987-07-14 Microbio Resources, Inc. Process for producing a naturally-derived carotene/oil composition by direct extraction from algae
JPH0634730B2 (ja) * 1986-06-16 1994-05-11 鐘淵化学工業株式会社 パルミトレイン酸の製造法
DK199887D0 (da) 1987-04-15 1987-04-15 Danisco Bioteknologi As Gaerstamme
FR2621327B1 (fr) 1987-10-06 1990-01-05 Commissariat Energie Atomique Procede de production et d'extraction de polysaccharides a partir d'une culture de porphyridium cruentum et dispositif pour la mise en oeuvre du procede
JPH0198494A (ja) 1987-10-09 1989-04-17 Agency Of Ind Science & Technol バイオリアクター
US5340742A (en) 1988-09-07 1994-08-23 Omegatech Inc. Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids
US5340594A (en) 1988-09-07 1994-08-23 Omegatech Inc. Food product having high concentrations of omega-3 highly unsaturated fatty acids
US6451567B1 (en) 1988-09-07 2002-09-17 Omegatech, Inc. Fermentation process for producing long chain omega-3 fatty acids with euryhaline microorganisms
US5130242A (en) * 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
US5173409A (en) 1989-12-08 1992-12-22 Ecogen Inc. Recovery of bt endotoxin protein from lysed cell mixtures
FR2656874B1 (fr) * 1990-01-11 1992-04-03 Commissariat Energie Atomique Procede de production et d'extraction d'anti-oxydants a partir d'une culture de micro-organismes et photobioreacteur pour la mise en óoeuvre de ce procede.
US5407957A (en) * 1990-02-13 1995-04-18 Martek Corporation Production of docosahexaenoic acid by dinoflagellates
US5658767A (en) 1991-01-24 1997-08-19 Martek Corporation Arachidonic acid and methods for the production and use thereof
US6270828B1 (en) 1993-11-12 2001-08-07 Cargrill Incorporated Canola variety producing a seed with reduced glucosinolates and linolenic acid yielding an oil with low sulfur, improved sensory characteristics and increased oxidative stability
FR2686619B1 (fr) * 1992-01-28 1995-07-13 Commissariat Energie Atomique Procede de production selective de lipides poly-insatures a partir d'une culture de micro-algues du type porphyridium et cuve utilisee dans ce procede.
US5476787A (en) 1992-04-24 1995-12-19 Director-General Of Agency Of Industrial Science And Technology Method of removing nitrogen impurities from water using hydrocarbon-producing microalga
DE4219360C2 (de) * 1992-06-12 1994-07-28 Milupa Ag Verfahren zur Gewinnung von Lipiden mit einem hohen Anteil von langkettig-hochungesättigten Fettsäuren
JPH06340577A (ja) * 1993-03-24 1994-12-13 Nippon Sanso Kk 13c標識イコサペンタエン酸とその誘導体及び製造方法
JPH072724A (ja) * 1993-03-24 1995-01-06 Nippon Sanso Kk 13c標識アラキドン酸とその誘導体及び製造方法
FR2719222B1 (fr) * 1994-05-02 1996-06-21 Rocher Yves Biolog Vegetale Vésicules lipidiques, leur procédé de fabrication et leurs applications.
US5928696A (en) * 1994-08-16 1999-07-27 Dr. Frische Gmbh Process for extracting native products which are not water-soluble from native substance mixtures by centrifugal force
US5583019A (en) 1995-01-24 1996-12-10 Omegatech Inc. Method for production of arachidonic acid
JP2764572B2 (ja) * 1995-04-17 1998-06-11 工業技術院長 ドコサヘキサエン酸生産能を有する新規微生物及びそれを用いたドコサヘキサエン酸の製造方法
WO1996033263A1 (fr) 1995-04-17 1996-10-24 JAPAN, represented by DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY Nouveaux micro-organismes capables de produire des acides gras hautement insatures et procede de production d'acides gras hautement insatures utilisant ces micro-organismes
ES2130515T3 (es) * 1995-05-04 1999-07-01 Nestle Sa Procedimiento para fraccionar acidos grasos.
GB9514649D0 (en) 1995-07-18 1995-09-13 Zeneca Ltd Extraction of triglycerides from microorganisms
JP3985035B2 (ja) * 1995-09-14 2007-10-03 独立行政法人産業技術総合研究所 (n−6)系ドコサペンタエン酸含有油脂ならびに該油脂の製造方法および用途
US6255505B1 (en) 1996-03-28 2001-07-03 Gist-Brocades, B.V. Microbial polyunsaturated fatty acid containing oil from pasteurised biomass
WO1998001536A1 (fr) 1996-07-03 1998-01-15 Sagami Chemical Research Center Micro-organismes produisant de l'acide docosahexanoique et procede de production de l'acide docosahexanoique
HU229062B1 (hu) 1996-07-23 2013-07-29 Nagase & Co Eljárás dokozahexaénsav és dokozapentaénsav elõállítására
US5951875A (en) 1996-12-20 1999-09-14 Eastman Chemical Company Adsorptive bubble separation methods and systems for dewatering suspensions of microalgae and extracting components therefrom
ATE408701T1 (de) * 1997-03-04 2008-10-15 Suntory Ltd Verfahren zur herstellung von hochungesättigten fettsäuren und hochungesättigte fettsäuren enthaltendes lipid
EP0979302B1 (en) 1997-05-02 2009-12-16 DSM IP Assets B.V. Isolation of carotenoid crystals from microbial biomass
US7585645B2 (en) 1997-05-27 2009-09-08 Sembiosys Genetics Inc. Thioredoxin and thioredoxin reductase containing oil body based products
EP1905309A1 (en) 1997-05-27 2008-04-02 SemBioSys Genetics Inc. Uses of oil bodies
US6566583B1 (en) 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
JP3836231B2 (ja) * 1997-10-17 2006-10-25 日本化学飼料株式会社 ホタテガイ中腸腺から得られる高度不飽和脂肪酸含有油及びその製造方法
CN1109482C (zh) 1997-11-12 2003-05-21 三菱电机株式会社 电发光体及其密封结构
JP2000041684A (ja) 1998-07-29 2000-02-15 Daicel Chem Ind Ltd 新規なd−アミノアシラーゼおよびその製造方法、並びに該d−アミノアシラーゼを利用したd−アミノ酸の製造方法
FR2782921B1 (fr) 1998-09-09 2002-09-20 Dior Christian Parfums Extrait lipidique de l'algue skeletonema, procede de preparation et utilisation dans des domaines cosmetique et pharmaceutique, notamment dermatologique
US6166231A (en) 1998-12-15 2000-12-26 Martek Biosciences Corporation Two phase extraction of oil from biomass
JP2000245492A (ja) 1999-03-02 2000-09-12 Kyowa Hakko Kogyo Co Ltd 微生物抽出脂質
US6344349B1 (en) 1999-12-06 2002-02-05 Decant Technologies Llc Process and system for electrical extraction of intracellular matter from biological matter
KR20140079870A (ko) * 2000-01-19 2014-06-27 마텍 바이오싸이언스스 코포레이션 무용매 추출 방법
DE10018213A1 (de) 2000-04-12 2001-10-25 Westfalia Separator Ind Gmbh Verfahren zur Fraktionierung von öl-und lecithinhaltigen nativen Rohstoffen
MXPA02010005A (es) 2000-04-12 2004-08-19 Westfalia Separator Ag Metodos para el fraccionamiento de materias primas nativas que contienen aceite y lipidos polares.
EP1178118A1 (en) * 2000-08-02 2002-02-06 Dsm N.V. Isolation of microbial oils
US20060060520A1 (en) 2001-06-25 2006-03-23 Bomberger David C Systems and methods using a solvent for the removal of lipids from fluids
US20030060509A1 (en) 2001-08-24 2003-03-27 Elswyk Mary Van Products containing highly unsaturated fatty acids for use by women and their children during stages of preconception, pregnancy and lactation/post-partum
US7419596B2 (en) 2001-12-12 2008-09-02 Martek Biosciences Corporation Extraction and winterization of lipids from oilseed and microbial sources
EP2921155B1 (en) 2002-05-03 2020-01-08 DSM IP Assets B.V. Methods for producing high-quality lipids by enzymatic liberation from biomass
EP2255667A1 (en) 2002-06-19 2010-12-01 DSM IP Assets B.V. Pasteurisation process for microbial cells and microbial oil
CN103834699A (zh) 2003-10-02 2014-06-04 Dsmip资产公司 使用改进量的氯和钾在微藻类中产生高水平的dha
KR101194236B1 (ko) 2004-03-01 2012-10-29 산토리 홀딩스 가부시키가이샤 장쇄 고도 불포화 지방산을 구성요소로서 포함하는 인지질 및 그 이용
EP1763575A4 (en) 2004-04-27 2009-09-23 Baxter Int REACTOR SYSTEM WITH AGITATION RESERVOIR
EP1597976B1 (en) 2004-05-21 2013-01-30 Nestec S.A. Use of polyol esters of fatty acids in aerated frozen confection with improved nutritional attributes
DE102004062141A1 (de) 2004-12-23 2006-07-06 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Verfahren zur Herstellung eines Rohöls aus Gemischen von Mikroorganismen und Pflanzen, das so hergestellte Öl sowie die spezifischen Verwendungen des so hergestellten und gegebenenfalls zusätzlich raffinierten Öls
DE102005003624A1 (de) 2005-01-26 2006-07-27 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Herstellung und Anwendung eines antioxidativ wirksamen Extraktes aus Crypthecodinium sp.
NZ563125A (en) 2005-06-03 2009-11-27 Mcfarlane Marketing Aust Pty L Lipid extract of mussels and method for preparation thereof
PL2447356T3 (pl) 2005-06-07 2016-10-31 Mikroorganizmy eukariotyczne do wytwarzania lipidów i przeciwutleniaczy
EP1903883A4 (en) 2005-07-01 2010-06-23 Martek Biosciences Corp OIL PRODUCT CONTAINING MULTIPLE UNSATURATED FATTY ACIDS AND ITS USES AND MANUFACTURING
US7527734B1 (en) 2005-11-15 2009-05-05 Shepherd Samuel L Rapid non-equilibrium decompression of microorganism-containing waste streams
AU2007213506A1 (en) 2006-02-07 2007-08-16 Universitetet I Oslo Omega 3
EP2044208A4 (en) 2006-07-05 2012-02-22 Photonz Corp Ltd PRODUCTION OF EPA AND ULTRA PURE POLAR LIPIDS FROM A BROADLY HETERATROPHE CULTURE
EP1887011A1 (en) 2006-08-09 2008-02-13 Thermphos Trading GmbH Alpha amino acid phosphonic acid compounds, method of preparation and use thereof
WO2008130372A2 (en) 2006-09-28 2008-10-30 Microbia, Inc. Production of sterols in oleaginous yeast and fungi
US20080083352A1 (en) 2006-10-10 2008-04-10 Ernest Peter Tovani Vehicle Table System
KR100810314B1 (ko) 2006-10-11 2008-03-04 삼성전자주식회사 휴대 단말기의 키 입력 장치
US8088614B2 (en) 2006-11-13 2012-01-03 Aurora Algae, Inc. Methods and compositions for production and purification of biofuel from plants and microalgae
CA2670985C (en) 2006-12-01 2015-06-09 North Carolina State University Process for conversion of biomass to fuel
BRPI0720852A2 (pt) 2006-12-22 2014-03-11 Danisco Us Inc Genecor Division Desemulsificação auxiliada por enzima de extratos de lipídio aquosos
EA020623B1 (ru) 2007-06-14 2014-12-30 Николос Митрополос Способ и система для выращивания морских водорослей для биотоплива
US20100226977A1 (en) 2007-08-29 2010-09-09 Aker Biomarine Asa Low viscosity phospholipid compositions
EP2198038B1 (en) 2007-09-12 2018-03-14 DSM IP Assets B.V. Method for producing biological oil using a nonsterile fermentor
JP4594998B2 (ja) * 2008-05-21 2010-12-08 株式会社日立製作所 エレベーターかごの速度検出装置の検査方法。
ITMI20081203A1 (it) 2008-06-30 2010-01-01 Eni Spa Procedimento per l'estrazione di acidi grassi da biomassa algale
EP2145942A1 (de) 2008-07-15 2010-01-20 Lonza Ltd. Verfahren zur Isolierung von Ölen aus Zellen und Biomasse
AU2009279677A1 (en) 2008-08-04 2010-02-11 Kai Bioenergy Continuous cultivation, harvesting, and oil extraction of photosynthetic cultures
PL2337857T3 (pl) 2008-10-02 2017-09-29 Gonzalez Ramon Ekstrakt z mikroalg zawierający 3-wielonienasycone kwasy tłuszczowe i sposób ekstrakcji oleju z mikroorganizmów
CN104770424A (zh) 2008-10-14 2015-07-15 索拉兹米公司 微藻生物质的食品组合物
SE534278C2 (sv) 2009-02-17 2011-06-28 Alfa Laval Corp Ab Ett kontinuerligt förfarande för isolering av oljor från alger eller mikroorganismer
US9296985B2 (en) 2009-03-10 2016-03-29 Valicor, Inc. Algae biomass fractionation
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
US8476060B2 (en) 2009-04-13 2013-07-02 Board Of Regents, The University Of Texas System Process for separating lipids from a biomass
BRPI1012026A2 (pt) 2009-05-26 2018-07-17 Solazyme Inc fracionamento de biomassa microbiana contendo óleo
KR101659765B1 (ko) 2009-09-28 2016-09-27 삼성전자주식회사 다중 모드 휴대용 단말기에서 전력 소모를 줄이기 위한 장치 및 방법
US20110256268A1 (en) 2010-04-14 2011-10-20 Solazyme, Inc. Oleaginous Yeast Food Compositions
JP5911479B2 (ja) 2010-06-01 2016-04-27 ディーエスエム アイピー アセッツ ビー.ブイ. 細胞からの脂質の抽出およびそれに由来する生産物
US9023625B2 (en) 2010-06-14 2015-05-05 Io-Mega Holding Corporation Methods for production of algae derived oils
EP2598641B1 (en) 2010-07-26 2014-05-21 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds from biomass
US9028696B2 (en) 2010-07-26 2015-05-12 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds from biomass
EP2600957A4 (en) 2010-08-06 2017-11-08 ICM, Inc. Bio-oil recovery systems and methods
US20120040428A1 (en) 2010-08-13 2012-02-16 Paul Reep Procedure for extracting of lipids from algae without cell sacrifice
US20120129244A1 (en) 2010-10-17 2012-05-24 Michael Phillip Green Systems, methods and apparatuses for dewatering, flocculating and harvesting algae cells
CN101985637B (zh) 2010-11-02 2014-05-07 嘉必优生物工程(武汉)有限公司 一种微生物油脂的提取方法
EP2450425B1 (en) 2010-11-08 2014-05-14 Neste Oil Oyj A method for lipid extraction from biomass
WO2012109642A1 (en) 2011-02-12 2012-08-16 Phycal, Inc. Aqueous extraction methods for high lipid microorganisms
CA2829296C (en) 2011-03-07 2019-10-29 ShuoCheng ZHANG Engineering thraustochytrid microorganisms
WO2012125611A2 (en) 2011-03-15 2012-09-20 Iowa State University Research Foundation Oil extraction from microalgae
FR2975705B1 (fr) 2011-05-27 2014-12-26 Roquette Freres Procede d'extraction du squalene a partir de microalgues
CN102433215A (zh) 2011-09-22 2012-05-02 厦门汇盛生物有限公司 一种从真菌或藻类中物理破壁提取油脂的方法
CN102388988B (zh) 2011-11-08 2013-01-23 中国农业科学院油料作物研究所 一种微生物油的分提方法
WO2013075116A2 (en) 2011-11-17 2013-05-23 Heliae Development, Llc Omega 7 rich compositions and methods of isolating omega 7 fatty acids
JP6216769B2 (ja) 2012-04-16 2017-10-18 ロケット フレールRoquette Freres 微細藻類により産生されるスクアレンを精製する方法
EP2867355A1 (en) 2012-06-29 2015-05-06 BP Biofuels UK Ltd. Process for separation of renewable materials from microorganisms
KR102435265B1 (ko) 2013-12-20 2022-08-22 디에스엠 아이피 어셋츠 비.브이. 미생물 세포로부터의 미생물 오일의 수득 방법
AR098893A1 (es) 2013-12-20 2016-06-22 Dsm Ip Assets Bv Proceso para obtener aceite microbiano a partir de células microbianas
PT2958982T (pt) 2013-12-20 2019-12-19 Mara Renewables Corp Métodos de recuperação de óleo a partir de microrganismos
AU2014364550A1 (en) 2013-12-20 2016-07-07 Dsm Ip Assets B.V. Process for extracting lipids for use in production of biofuels
JP6705581B2 (ja) 2013-12-20 2020-06-03 ディーエスエム アイピー アセッツ ビー.ブイ.Dsm Ip Assets B.V. 微生物細胞から微生物油を入手するための方法
KR102552228B1 (ko) 2013-12-20 2023-07-05 디에스엠 아이피 어셋츠 비.브이. 미생물 세포로부터의 미생물 오일의 수득 방법
CN105829539B (zh) 2013-12-20 2023-11-10 帝斯曼营养品股份公司 从微生物中回收油的方法
SG11201605009RA (en) 2013-12-20 2016-07-28 Dsm Ip Assets Bv Processes for obtaining microbial oil from microbial cells
US10472587B2 (en) 2014-07-07 2019-11-12 Commonwealth Scientific And Industrial Research Organisation Processes for producing industrial products from plant lipids

Also Published As

Publication number Publication date
AU2012200890A1 (en) 2012-03-08
HUP0300556A2 (hu) 2003-06-28
AU2014203384B2 (en) 2016-03-03
EP2295595B1 (en) 2019-05-01
US20020001833A1 (en) 2002-01-03
US20040229325A1 (en) 2004-11-18
IL206960A0 (en) 2010-12-30
EP1252324B1 (en) 2010-10-20
NO20110858L (no) 2002-09-17
JP5756137B2 (ja) 2015-07-29
KR20140079870A (ko) 2014-06-27
EP2295595A1 (en) 2011-03-16
AU2005202980A1 (en) 2005-08-04
US20140212936A1 (en) 2014-07-31
US20170298288A1 (en) 2017-10-19
CA2397655A1 (en) 2001-07-26
DK1252324T3 (da) 2010-12-20
EP2295594A1 (en) 2011-03-16
KR20100051131A (ko) 2010-05-14
MX350779B (es) 2017-09-18
KR101591834B1 (ko) 2016-02-18
AU2016203318A1 (en) 2016-06-09
RU2002119551A (ru) 2004-02-20
ES2352001T3 (es) 2011-02-14
IL206961A (en) 2011-11-30
JP2013099365A (ja) 2013-05-23
US9738851B2 (en) 2017-08-22
US10329515B2 (en) 2019-06-25
DE60143287D1 (de) 2010-12-02
WO2001053512A1 (en) 2001-07-26
KR101429238B1 (ko) 2014-08-12
AU2963601A (en) 2001-07-31
AU2014203384A1 (en) 2014-07-10
MX297659B (en) 2012-03-29
NO20023449D0 (no) 2002-07-18
ES2735987T3 (es) 2019-12-23
AU780619B2 (en) 2005-04-07
MX232239B (es) 2005-11-18
KR100995575B1 (ko) 2010-11-19
JP2005278650A (ja) 2005-10-13
KR20110000592A (ko) 2011-01-03
US20080038800A1 (en) 2008-02-14
NO20023449L (no) 2002-09-17
HUP0300556A3 (en) 2010-03-29
CN101463371A (zh) 2009-06-24
MX275361B (en) 2010-04-21
JP2003520046A (ja) 2003-07-02
US20080044876A1 (en) 2008-02-21
CZ303446B6 (cs) 2012-09-19
ES2675517T3 (es) 2018-07-11
KR20030013367A (ko) 2003-02-14
NZ520287A (en) 2004-01-30
JP4537887B2 (ja) 2010-09-08
CA2772540A1 (en) 2001-07-26
RU2336307C2 (ru) 2008-10-20
IL150772A0 (en) 2003-02-12
KR20080007279A (ko) 2008-01-17
JP2010051328A (ja) 2010-03-11
PL356587A1 (en) 2004-06-28
US7662598B2 (en) 2010-02-16
HK1050716A1 (en) 2003-07-04
MXPA02007092A (es) 2003-02-24
CN100460513C (zh) 2009-02-11
AU2018200956A1 (en) 2018-03-01
US20080044875A1 (en) 2008-02-21
PT1252324E (pt) 2010-12-16
IL150772A (en) 2010-06-16
KR20120070588A (ko) 2012-06-29
EP1252324A1 (en) 2002-10-30
EP1252324A4 (en) 2005-02-09
CA2397655C (en) 2012-06-05
ZA200205790B (en) 2003-07-28
AU2012200890B2 (en) 2014-07-31
KR20130032395A (ko) 2013-04-01
BR0107699B1 (pt) 2014-05-27
IL201756A (en) 2011-06-30
CN1416469A (zh) 2003-05-07
KR101429236B1 (ko) 2014-08-12
US7351558B2 (en) 2008-04-01
KR101180462B1 (ko) 2012-09-06
JP4020642B2 (ja) 2007-12-12
ATE485385T1 (de) 2010-11-15
AU2019226124A1 (en) 2019-09-26
JP5722536B2 (ja) 2015-05-20
AU2005202980B2 (en) 2008-07-10
US20190256797A1 (en) 2019-08-22
EP2302065A1 (en) 2011-03-30
US7781193B2 (en) 2010-08-24
JP2015133969A (ja) 2015-07-27
KR20150020609A (ko) 2015-02-26
US6750048B2 (en) 2004-06-15
AU2005202980C1 (en) 2009-04-02
EP2295594B1 (en) 2018-04-04

Similar Documents

Publication Publication Date Title
BR0107699A (pt) Processo de extração sem o uso de solventes e lipìdeos obtidos
BR0107832A (pt) Processo de extração sem o uso de solvente e lipìdios obtidos
BRPI0410680A (pt) processo para a recuperação de 1,3-propanodiol de um caldo de fermentação
AR061992A1 (es) Mejoras referidas a nanodispersiones
AR030820A1 (es) Desulfuracion oxidativa de combustibles fosiles con ultrasonido
CO5630034A1 (es) Metodo para producir esteres de alquilo
TR200708042T1 (tr) Proses yağı, asfaltı giderilmiş yağ üretme işlemi, ekstrakt üretme işlemi ve proses yağı üretme işlemi.
BR0313251A (pt) Métodos de extração de polìmero
Rodríguez-López et al. Extraction, separation and characterization of lipopeptides and phospholipids from corn steep water
EP1894973A4 (en) PROCESS FOR PRODUCING A PVP-FULLERENE COMPLEX AND AQUEOUS SOLUTION OF THIS COMPLEX
DE60234277D1 (de) Verbessertes verfahren zur herstellung von lycopin durch fermentation ausgewählter stämme von blakeslea trispora.
PE6297A1 (es) Un metodo de identificar un producto de petroleo que contiene un marcador de base reactiva
IL194315A (en) A process for isolating and stabilizing low molecular weight aminoglycans from eggshell debris
AR026076A1 (es) Un metodo para producir una preparacion de liposomas mediante secado al vacio
PE20100240A1 (es) Metodo para producir una composicion que comprende la epotilona (1s, 3s, 7s, 10r,11s,12s,16r)7, 11hidroxi-3-(2-metil-benzotiazol-5-il)-10-(prop-2-1-il)-8,8-12,16-tetrametil-4,17dioxabiciclo[14.1.0]heptade can-5,9-diona
WO2008129973A1 (ja) 低分子有機化合物インターカレート型中空繊維状有機ナノチューブ及びその製造方法
BR9914812A (pt) Processo para a clivagem enzimática de rutinosìdeos
EP1424341A3 (en) Production method for purine nucleotide derivative disodium crystals and alcohol removing method
BR9808011A (pt) Processo para a purificação de caprolactama
KR960034173A (ko) 2,2,6,6-테트라메틸피페리딘-4-온의 메틸화 방법
BRPI0506222A (pt) aperfeiçoamento em processo de produção de caulim grosseiro com elevada alvura e baixa viscosidade para a utilização como revestimento
BR0112064A (pt) Processo para a preparação de derivados da quinolina
AR027687A1 (es) Procedimiento para preparar camptotecina
TW200602497A (en) Solventless extraction process
DE69912824T2 (de) Papierprodukte und verfahren zu deren herstellung

Legal Events

Date Code Title Description
B25F Entry of change of name and/or headquarter and transfer of application, patent and certif. of addition of invention: change of name on requirement

Owner name: OMEGATECH, INC. (US)

Free format text: A FIM DE ATENDER A ALTERACAO DE NOME REQUERIDA NA PETICAO NO 066989/RJ DE 03/12/2003, FAVOR REAPRESENTAR DOCUMENTO DE ALTERACAO DE NOME COM A DEVIDA LEGALIZACAO CONSULAR.

B25L Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled

Owner name: OMEGATECH, INC. (US)

Free format text: REFERENTE A RPI 1854 COD. (25.6) DE 18/07/2006, POR TER SIDO INDEVIDO.

B25D Requested change of name of applicant approved

Owner name: MARTEK BIOSCIENCES BOULDER CORPORATION (US)

Free format text: ALTERADO DE: OMEGATECH, INC.

B25A Requested transfer of rights approved

Owner name: MARTEK BIOSCIENCES CORPORATION (US)

Free format text: TRANSFERIDO DE: MARTEK BIOSCIENCES BOULDER CORPORATION

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B25A Requested transfer of rights approved

Owner name: DSM IP ASSETS B.V. (NL)

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 27/05/2014, OBSERVADAS AS CONDICOES LEGAIS.