HRP20000714B1 - NOVEL CD19xCD3 SPECIFIC POLYPEPTIDES AND USES THEREOF - Google Patents

NOVEL CD19xCD3 SPECIFIC POLYPEPTIDES AND USES THEREOF

Info

Publication number
HRP20000714B1
HRP20000714B1 HR20000714A HRP20000714A HRP20000714B1 HR P20000714 B1 HRP20000714 B1 HR P20000714B1 HR 20000714 A HR20000714 A HR 20000714A HR P20000714 A HRP20000714 A HR P20000714A HR P20000714 B1 HRP20000714 B1 HR P20000714B1
Authority
HR
Croatia
Prior art keywords
novel
specific polypeptides
antigen
domain
cd19xcd3
Prior art date
Application number
HR20000714A
Other languages
English (en)
Croatian (hr)
Inventor
Doerken Bernd
Riethmueller Gert
Kufer Peter
Lutterbuese Ralf
Bargou Ralf
Loeffler Anja
Original Assignee
Micromet Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8231795&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20000714(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Micromet Ag filed Critical Micromet Ag
Publication of HRP20000714A2 publication Critical patent/HRP20000714A2/hr
Publication of HRP20000714B1 publication Critical patent/HRP20000714B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HR20000714A 1998-04-21 2000-10-20 NOVEL CD19xCD3 SPECIFIC POLYPEPTIDES AND USES THEREOF HRP20000714B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98107269 1998-04-21
PCT/EP1999/002693 WO1999054440A1 (en) 1998-04-21 1999-04-21 CD19xCD3 SPECIFIC POLYPEPTIDES AND USES THEREOF

Publications (2)

Publication Number Publication Date
HRP20000714A2 HRP20000714A2 (en) 2001-12-31
HRP20000714B1 true HRP20000714B1 (en) 2006-03-31

Family

ID=8231795

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20000714A HRP20000714B1 (en) 1998-04-21 2000-10-20 NOVEL CD19xCD3 SPECIFIC POLYPEPTIDES AND USES THEREOF

Country Status (29)

Country Link
US (2) US7112324B1 (ko)
EP (2) EP1071752B1 (ko)
JP (1) JP4169478B2 (ko)
KR (1) KR100508289B1 (ko)
CN (1) CN1302103C (ko)
AT (1) ATE244758T1 (ko)
AU (1) AU761587B2 (ko)
BR (1) BRPI9909860B8 (ko)
CA (1) CA2326389C (ko)
CU (1) CU23252B7 (ko)
CZ (1) CZ302070B6 (ko)
DE (1) DE69909459T2 (ko)
DK (1) DK1071752T3 (ko)
ES (1) ES2203141T3 (ko)
HK (1) HK1037674A1 (ko)
HR (1) HRP20000714B1 (ko)
HU (1) HU229039B1 (ko)
ID (1) ID27512A (ko)
IL (2) IL138857A0 (ko)
NO (1) NO326523B1 (ko)
NZ (1) NZ507381A (ko)
PL (1) PL199747B1 (ko)
PT (1) PT1071752E (ko)
RU (1) RU2228202C2 (ko)
SI (1) SI1071752T1 (ko)
SK (1) SK286683B6 (ko)
TR (1) TR200003087T2 (ko)
WO (1) WO1999054440A1 (ko)
ZA (1) ZA200005866B (ko)

Families Citing this family (406)

* Cited by examiner, † Cited by third party
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US7820166B2 (en) 2002-10-11 2010-10-26 Micromet Ag Potent T cell modulating molecules
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