DE69526143D1 - Abtrennfreier, spezifischer Bindungsassay mit Anti-Inhibitor-Antikörpern - Google Patents

Abtrennfreier, spezifischer Bindungsassay mit Anti-Inhibitor-Antikörpern

Info

Publication number
DE69526143D1
DE69526143D1 DE69526143T DE69526143T DE69526143D1 DE 69526143 D1 DE69526143 D1 DE 69526143D1 DE 69526143 T DE69526143 T DE 69526143T DE 69526143 T DE69526143 T DE 69526143T DE 69526143 D1 DE69526143 D1 DE 69526143D1
Authority
DE
Germany
Prior art keywords
detachable
specific binding
binding assay
inhibitor antibodies
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69526143T
Other languages
English (en)
Other versions
DE69526143T2 (de
Inventor
John L Daiss
Kevin M Gorman
Carolyn R Hinchman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Clinical Diagnostics Inc
Original Assignee
Johnson and Johnson Clinical Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson and Johnson Clinical Diagnostics Inc filed Critical Johnson and Johnson Clinical Diagnostics Inc
Application granted granted Critical
Publication of DE69526143D1 publication Critical patent/DE69526143D1/de
Publication of DE69526143T2 publication Critical patent/DE69526143T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/969—Multiple layering of reactants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/97—Test strip or test slide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/816—Alkaloids, amphetamines, and barbiturates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/822—Identified hapten

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69526143T 1994-05-31 1995-05-30 Abtrennfreier, spezifischer Bindungsassay mit Anti-Inhibitor-Antikörpern Expired - Lifetime DE69526143T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/250,883 US5565326A (en) 1994-05-31 1994-05-31 Separation-free specific binding assays using anti-inhibitor antibodies

Publications (2)

Publication Number Publication Date
DE69526143D1 true DE69526143D1 (de) 2002-05-08
DE69526143T2 DE69526143T2 (de) 2002-09-26

Family

ID=22949546

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69526143T Expired - Lifetime DE69526143T2 (de) 1994-05-31 1995-05-30 Abtrennfreier, spezifischer Bindungsassay mit Anti-Inhibitor-Antikörpern

Country Status (6)

Country Link
US (1) US5565326A (de)
EP (1) EP0685740B1 (de)
JP (1) JPH0854392A (de)
AU (1) AU2041095A (de)
CA (1) CA2150496A1 (de)
DE (1) DE69526143T2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5916757A (en) * 1994-05-31 1999-06-29 Johnson & Johnson Clinical Diagnostics, Inc. Specific binding assay using enzyme inhibitor and anti-inhibitor antibodies
US20040049351A1 (en) * 2002-08-28 2004-03-11 Matson Robert S. Immunosorbent assay in microarray format
WO2006070790A1 (ja) * 2004-12-27 2006-07-06 Brother Kogyo Kabushiki Kaisha ラベル作成装置、マーク及びテープエンド検出装置、ラベル用テープロール及びカートリッジ、マーク付テープ
US7910378B2 (en) * 2007-12-14 2011-03-22 Siemens Healthcare Diagnostics Inc. Methods for detection of hydrophobic drugs
US20210199649A1 (en) * 2018-05-17 2021-07-01 Techno Medica Co., Ltd. Competitive immunochromatographic analysis method and immunochromatographic sensor

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3992158A (en) 1973-08-16 1976-11-16 Eastman Kodak Company Integral analytical element
US4161515A (en) * 1973-10-02 1979-07-17 Syva Company Double receptor fluorescent immunoassay
US3935074A (en) * 1973-12-17 1976-01-27 Syva Company Antibody steric hindrance immunoassay with two antibodies
US4383031A (en) 1975-04-28 1983-05-10 Miles Laboratories, Inc. Homogeneous chemiluminescent specific binding assay
DE2559004C2 (de) 1975-12-29 1978-09-28 Ibm Deutschland Gmbh, 7000 Stuttgart Anordnung zur Prüfung von elektrischen Prüflingen mit einer Vielzahl von Prüfkontakten
US4233401A (en) * 1977-07-14 1980-11-11 Syva Company Antienzyme homogeneous competitive binding assay
US4430263A (en) * 1978-09-18 1984-02-07 Abbott Laboratories Hapten-inhibitor immunoassay
US4258001A (en) 1978-12-27 1981-03-24 Eastman Kodak Company Element, structure and method for the analysis or transport of liquids
JPS55164356A (en) 1979-06-08 1980-12-22 Fuji Photo Film Co Ltd Multi-layer analysis sheet for liquid sample analysis
JPS57101761A (en) 1980-12-17 1982-06-24 Konishiroku Photo Ind Co Ltd Analyzing element
JPS5818167A (ja) * 1981-07-24 1983-02-02 Fuji Photo Film Co Ltd 分析フイルム及びこれを用いる分析方法
JPS58209994A (ja) * 1982-05-10 1983-12-07 Fujirebio Inc 活性蛋白等固定化物を用いた抗原の測定方法
EP0116454B1 (de) 1983-02-11 1987-04-29 National Research Development Corporation Erhöhte lumineszierende oder luminometrische Prüfung
EP0119767B1 (de) * 1983-03-11 1990-11-22 FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. Verfahren zur Bestimmung von Liganden
IT1199088B (it) * 1984-03-09 1988-12-30 Miles Italiana Saggio di legame specifico mediante impiego di anti-g6pdh come marcante
GB8420053D0 (en) 1984-08-07 1984-09-12 Secr Social Service Brit Enhanced luminescent/luminometric assay
WO1987006006A1 (en) * 1986-03-26 1987-10-08 Murex Corporation Anti-enzyme antibody immunoassay
FR2602592B1 (fr) 1986-08-06 1989-06-30 Alain Baret Utilisation du systeme enzymatique xanthine-oxydase en immuno-analyse, procedes de dosage correspondants et coffrets de reactifs necessaires pour la mise en oeuvre de ces procedes.
US4997772A (en) 1987-09-18 1991-03-05 Eastman Kodak Company Water-insoluble particle and immunoreactive reagent, analytical elements and methods of use
US5177023A (en) 1987-08-03 1993-01-05 Eastman Kodak Company Water-insoluble reagent elements containing same and methods of use
CA1300499C (en) 1987-08-03 1992-05-12 Susan J. Danielson Water-insoluble reagent, elements containing same and methods of use
US5024935A (en) 1987-12-18 1991-06-18 Eastman Kodak Company Dye-providing composition, diagnostic test kit and their use in method for ligand determination using peroxidase labeled-receptor
US5104793A (en) * 1988-02-16 1992-04-14 Boehringer Mannheim Corporation Method for determining an analyte in a liquid sample using a zoned test device and an inhibitor for a label used in said method
US5064755A (en) * 1988-08-04 1991-11-12 Abbott Laboratories Two-site confirmatory assay
IT1235349B (it) * 1988-12-23 1992-06-30 Biodata Spa Saggio immunologico per determinazioni in fase omogenea
US5262297A (en) 1990-06-18 1993-11-16 Eastman Kodak Company Specific binding analytical and separation methods using carboxy containing polymers
EP0517327B1 (de) 1991-06-07 2001-08-16 Johnson & Johnson Clinical Diagnostics, Inc. Immunoassays unter Verwendung von markierten Hapten-Analogen
US5972630A (en) * 1991-08-19 1999-10-26 Dade Behring Marburg Gmbh Homogeneous immunoassays using enzyme inhibitors
US5252457A (en) 1991-10-08 1993-10-12 Eastman Kodak Company Wash composition containing signal stop reagent, test kit and method of use with peroxidase-labeled specific binding ligand

Also Published As

Publication number Publication date
EP0685740A2 (de) 1995-12-06
EP0685740B1 (de) 2002-04-03
AU2041095A (en) 1995-12-07
EP0685740A3 (de) 1996-04-03
JPH0854392A (ja) 1996-02-27
DE69526143T2 (de) 2002-09-26
CA2150496A1 (en) 1995-12-01
US5565326A (en) 1996-10-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN