HK1019553A1 - Therapeutic methods and compositions involving isoflavones - Google Patents

Therapeutic methods and compositions involving isoflavones

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Publication number
HK1019553A1
HK1019553A1 HK99104669A HK99104669A HK1019553A1 HK 1019553 A1 HK1019553 A1 HK 1019553A1 HK 99104669 A HK99104669 A HK 99104669A HK 99104669 A HK99104669 A HK 99104669A HK 1019553 A1 HK1019553 A1 HK 1019553A1
Authority
HK
Hong Kong
Prior art keywords
therapeutic methods
compositions involving
isoflavones
involving isoflavones
compositions
Prior art date
Application number
HK99104669A
Other languages
English (en)
Inventor
Graham Edmund Kelly
George Eustace Joannou
Original Assignee
Novogen Res Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novogen Res Pty Ltd filed Critical Novogen Res Pty Ltd
Publication of HK1019553A1 publication Critical patent/HK1019553A1/xx

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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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HK99104669A 1996-08-30 1999-10-21 Therapeutic methods and compositions involving isoflavones HK1019553A1 (en)

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HK07110769.1A HK1105580A1 (en) 1996-08-30 2007-10-04 Use of isoflavone compounds in the manufacture of medicament and composition comprising the same
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Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE275959T1 (de) 1992-05-19 2004-10-15 Graham Edmund Kelly Verwendung von isoflavon phyto-östrogen extrakten von soja oder klee
AUPO203996A0 (en) 1996-08-30 1996-09-26 Novogen Research Pty Ltd Therapeutic uses
US6146668A (en) 1997-04-28 2000-11-14 Novogen, Inc. Preparation of isoflavones from legumes
WO1998048790A1 (en) * 1997-04-28 1998-11-05 Anticancer, Inc. Use of genistein and related compounds to treat certain sex hormone related conditions
WO1998050026A1 (en) * 1997-05-01 1998-11-12 Novogen Inc Treatment or prevention of menopausal symptoms and osteoporosis
AUPP112497A0 (en) * 1997-12-24 1998-01-22 Novogen Research Pty Ltd Compositions and method for protecting skin from UV induced immunosupression and skin damage
US5958946A (en) * 1998-01-20 1999-09-28 Styczynski; Peter Modulation of hair growth
WO1999047119A1 (en) * 1998-03-16 1999-09-23 The Procter & Gamble Company Methods for regulating skin appearance
JPH11269066A (ja) * 1998-03-20 1999-10-05 Kao Corp 経口用美白剤及び美白用食品
AUPP260798A0 (en) * 1998-03-26 1998-04-23 Novogen Research Pty Ltd Treatment of medical related conditions with isoflavone containing extracts of clover
AU4204099A (en) * 1998-05-27 1999-12-13 Sherwood L. Gorbach Isoflavonoids for treatment and prevention of migraine headaches
US8093293B2 (en) 1998-07-06 2012-01-10 Johnson & Johnson Consumer Companies, Inc. Methods for treating skin conditions
US8106094B2 (en) 1998-07-06 2012-01-31 Johnson & Johnson Consumer Companies, Inc. Compositions and methods for treating skin conditions
GB9814620D0 (en) * 1998-07-06 1998-09-02 Karobio Ab Vasculoprotector
FR2781154B1 (fr) * 1998-07-15 2001-09-07 Lafon Labor Composition therapeutique a base d'isoflavonoides destinee a etre utilisee dans le traitement des tumeurs par des agents cytotoxiques
AU5440799A (en) * 1998-09-17 2000-04-10 Guido Schnyder Method and drug for the treatment of coronary heart disease and for the prevention of restenosis after percutaneous transluminal coronary angioplasty
US6399655B1 (en) 1998-12-22 2002-06-04 Johns Hopkins University, School Of Medicine Method for the prophylactic treatment of cataracts
AUPP868599A0 (en) * 1999-02-15 1999-03-11 Novogen Research Pty Ltd Production of isoflavone derivatives
MXPA01010423A (es) * 1999-04-16 2002-03-27 Astrazeneca Ab Ligandos del receptor beta de estrogeno.
US20040072765A1 (en) * 1999-04-28 2004-04-15 Novogen Research Pty Ltd. Cardiovascular and bone treatment using isoflavones
US20090233999A1 (en) * 1999-09-06 2009-09-17 Novogen Research Pty Ltd Compositions and therapeutic methods involving isoflavones and analogues thereof
AUPQ266199A0 (en) * 1999-09-06 1999-09-30 Novogen Research Pty Ltd Compositions and therapeutic methods involving isoflavones and analogues thereof
AUPQ520300A0 (en) * 2000-01-21 2000-02-17 Novogen Research Pty Ltd Food product and process
EP1132084A1 (en) * 2000-03-06 2001-09-12 Docteur Nature Srl Transdermal device for the slow release of soybean derived vegetable estrogens
US20020010141A1 (en) * 2000-03-31 2002-01-24 Jonathan Ingram Isoflavones for treatment of obesity
DE60128801T2 (de) 2000-06-14 2008-06-26 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Isoflavone gegen strahlungsinduzierte Sterblichkeit
US6248790B1 (en) 2000-06-29 2001-06-19 Parker Hughes Institute Treatment of inflammation with 2,4,6-trihydroxy-alpha-rho-methoxyphenylacetophenone, or its pharmaceutically acceptable derivatives
ATE400285T1 (de) 2000-08-16 2008-07-15 Unilever Nv Mischungen von isoflavonen und flavonen
AUPQ968700A0 (en) * 2000-08-28 2000-09-21 Intreat Pty Limited Treatment of urinary incontinence
FR2815033B1 (fr) * 2000-10-06 2003-09-05 Negma Lab Derives de 7-carboxy-flavones, porcede pour leur preparation et leur application en therapeutique
US8431550B2 (en) 2000-10-27 2013-04-30 Johnson & Johnson Consumer Companies, Inc. Topical anti-cancer compositions and methods of use thereof
AUPR255401A0 (en) * 2001-01-16 2001-02-08 Novogen Research Pty Ltd Regulation of lipids and/or bone density and compositions therefor
US7192615B2 (en) 2001-02-28 2007-03-20 J&J Consumer Companies, Inc. Compositions containing legume products
AUPR363301A0 (en) 2001-03-08 2001-04-05 Novogen Research Pty Ltd Dimeric isoflavones
US20050119301A1 (en) * 2001-03-16 2005-06-02 Alan Husband Treatment of restenosis
AU2006200292B2 (en) * 2001-03-16 2007-11-22 Novogen Research Pty Ltd Treatment of restenosis
JP4256679B2 (ja) * 2001-03-16 2009-04-22 ノボゲン リサーチ ピーティーワイ リミテッド 再狭窄の治療方法
DE10114305A1 (de) * 2001-03-23 2002-09-26 Beiersdorf Ag Kosmetische und dermatologische Zubereitungen mit einem Gehalt an Isoflavonen und Verwendung von Isoflavonen zur Herstellung kosmetischer und dermatologischer Zubereitungen zur Reduktion des Sebumgehaltes der Haut
US6787151B2 (en) 2001-08-10 2004-09-07 Lipton, Division Of Conopco, Inc. Composition for lowering blood cholesterol
AUPR846401A0 (en) * 2001-10-25 2001-11-15 Novogen Research Pty Ltd 6-Hydroxy isoflavones, derivatives and medicaments involving same
CA2478392A1 (en) * 2002-04-09 2003-10-23 Novogen Research Pty Ltd Therapeutic methods and compositions involving isoflav-3-ene and isoflavan structures
JP2006504409A (ja) * 2002-07-24 2006-02-09 チルドレンズ ホスピタル メディカル センター 鏡像異性のエクオールを含有する組成物および製品、およびその製造方法
US8668914B2 (en) * 2002-07-24 2014-03-11 Brigham Young University Use of equol for treating skin diseases
AU2003257264B2 (en) * 2002-09-06 2007-09-13 Novogen Research Pty Ltd Repair of DNA mutagenic damage
AU2002951271A0 (en) * 2002-09-06 2002-09-19 Novogen Research Pty Ltd Repair of dna mutagenic damage
CA2499602A1 (en) * 2002-09-23 2004-04-01 Graham Edmund Kelly Skin photoageing and actinic damage treatment
AU2003264176B2 (en) * 2002-09-23 2008-12-11 Novogen Research Pty Ltd Skin photoageing and actinic damage treatment
AU2002951833A0 (en) 2002-10-02 2002-10-24 Novogen Research Pty Ltd Compositions and therapeutic methods invloving platinum complexes
US8580846B2 (en) 2002-10-29 2013-11-12 Brigham Young University Use of equol for ameliorating or preventing neuropsychiatric and neurodegenerative diseases or disorders
JP4889944B2 (ja) * 2002-10-29 2012-03-07 コロラド ステート ユニバーシティー リサーチ ファウンデーション アンドロゲンによって仲介される疾患を治療するためのエクオールの使用
JP2007511542A (ja) * 2003-11-18 2007-05-10 ノボゲン リサーチ ピーティーワイ リミテッド イソフラボノイドプロドラッグ、その組成物、それらを使用する治療法
US20060167037A1 (en) * 2003-11-19 2006-07-27 Kelly Graham E Combinational radiotherapy and chemotherapy compositions and methods
US20050143323A1 (en) * 2003-12-30 2005-06-30 Henley E. C. Isoflavone therapy for treating urinary incontinence
JP2005289817A (ja) * 2004-03-09 2005-10-20 Daicho Kikaku:Kk 抗癌剤
EP1740191A4 (en) * 2004-04-28 2008-07-30 Univ Brigham Young USE OF EQUOL FOR THE TREATMENT OF SKIN DISEASES
CN100351248C (zh) * 2004-07-05 2007-11-28 南京大学 染料木素衍生物及其制法和用途
EP1809618B1 (en) 2004-09-21 2013-07-17 Marshall Edwards, Inc. Chroman derivatives, medicaments and use in therapy
WO2006032085A1 (en) 2004-09-21 2006-03-30 Novogen Research Pty Ltd Substituted chroman derivatives, medicaments and use in therapy
US8080675B2 (en) * 2004-09-21 2011-12-20 Marshall Edwards, Inc. Chroman derivatives, medicaments and use in therapy
US20060189543A1 (en) * 2005-02-23 2006-08-24 Rosenbloom Richard A Compositions and methods for the treatment of leukemia
CN101184756B (zh) * 2005-03-24 2011-08-03 诺沃根研究控股有限公司 异类黄酮二聚物
US7528267B2 (en) * 2005-08-01 2009-05-05 Girindus America, Inc. Method for enantioselective hydrogenation of chromenes
ES2542989T3 (es) 2005-10-12 2015-08-13 Idera Pharmaceuticals, Inc. Compuestos oligonucleótidos inmuno reguladores (IRO) para modular la respuesta inmune basada en receptor semejante a Toll
KR101346504B1 (ko) * 2005-12-06 2013-12-31 오츠카 세이야쿠 가부시키가이샤 에쿠올 함유 대두 배축 발효물 및 그의 제조 방법
EP2084141A4 (en) * 2006-10-30 2010-07-21 Novogen Res Pty Ltd PREVENTION AND REVERSION OF CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY
US8221803B1 (en) 2007-06-25 2012-07-17 OncoNatural Solutions, Inc. Composition for prostate health
CN105832717A (zh) * 2008-07-25 2016-08-10 爱默蕾大学 用7,8-二羟基黄酮及其衍生物治疗各种病症
CN102281880A (zh) * 2008-10-06 2011-12-14 艾德拉药物股份有限公司 类Toll受体抑制剂在高胆固醇血症和高脂血症及相关疾病的预防和治疗中的用途
CA2743661C (en) 2008-11-14 2017-01-03 Heartlink Limited Aryl di-substituted propenone compounds
CN101716135B (zh) * 2010-01-08 2012-11-14 山西医科大学 大豆异黄酮固体分散体栓剂及其制备方法
EP2579870B1 (en) 2010-06-09 2018-02-14 Emory University Trkb agonists and methods of use
JP6013349B2 (ja) 2010-11-01 2016-10-25 メイ ファーマ, インク.Mei Pharma, Inc. 癌の処置のためのイソフラボノイド化合物および方法
CN103415302A (zh) 2010-11-19 2013-11-27 艾德拉药物股份有限公司 调控基于toll-样受体的免疫应答的免疫调节寡核苷酸(iro)化合物
CN102503922A (zh) * 2011-11-07 2012-06-20 吉首大学 黄烷醇(异黄烷醇)类尿素酶抑制剂及其合成和用途
CN103127053B (zh) * 2011-11-22 2014-05-21 沈阳药科大学 6-[2-(二甲氨基)乙氧基]黄酮的医药用途
US20130224318A1 (en) * 2012-02-29 2013-08-29 Avon Products, Inc. Use of CPT-1 Modulators and Compositions Thereof
CN102784135B (zh) * 2012-07-05 2014-11-05 西安交通大学 基于雌马酚激活BKCa通道的应用
US9593125B2 (en) 2012-07-27 2017-03-14 Emory University Heterocyclic flavone derivatives, compositions, and methods related thereto
CN102846595B (zh) * 2012-09-21 2013-08-28 沈阳药科大学 黄酮类化合物wx-03用于舒张血管平滑肌的用途
CN103030647B (zh) * 2013-01-16 2014-10-29 山东省分析测试中心 一种光甘草定的合成方法
EP2981530B1 (en) * 2013-04-04 2020-02-12 The Administrators of the Tulane Educational Fund Enhanced osteogenic activity of daidzein analogs on human mesenchymal stem cells
JP6371055B2 (ja) * 2013-12-20 2018-08-08 株式会社ダイセル イソフラバノン類の製造方法
CN105777693A (zh) * 2014-12-22 2016-07-20 王靖林 一种雌马酚的合成方法
MX2017010002A (es) 2015-02-02 2018-02-09 Mei Pharma Inc Terapias de combinacion.
EP3281626B1 (en) * 2015-04-06 2023-08-23 LG Household & Health Care Ltd. Soluble microneedle for delivering poorly-soluble drug
CN105153094B (zh) * 2015-07-08 2017-09-15 江苏省中国科学院植物研究所 碱蓬黄酮c及其制备方法和用途
JP2019513827A (ja) * 2016-04-06 2019-05-30 ノクソファーム リミティド 標的化薬物送達
JP2019513828A (ja) 2016-04-06 2019-05-30 ノクソファーム リミティド 改善された薬物動態を有するイソフラボノイド組成物
RU2018137897A (ru) * 2016-04-06 2020-05-13 Ноксофарм Лимитед Пути улучшения лечения рака
EP3439642A4 (en) * 2016-04-06 2019-11-13 Noxopharm Limited IMPROVEMENTS IN RADIATION THERAPY
AU2017254774B2 (en) 2016-04-22 2021-10-21 Noxopharm Limited Chemotherapy improvements
CN108409701B (zh) * 2017-02-10 2020-09-25 山东康迈祺生物科技有限公司 一种二氢大豆苷元的制备方法
CN110590727A (zh) * 2019-09-16 2019-12-20 西安联泽生物科技有限公司 一种雌马酚的制备方法
JP2023519990A (ja) 2020-03-30 2023-05-15 ノクソファーム リミティド 感染に関連する炎症の治療のための方法

Family Cites Families (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US35074A (en) * 1862-04-29 Improvement bn snow-plows for railroads
US498631A (en) * 1893-05-30 Nut-lock
DE1518002C3 (de) 1965-01-02 1975-01-23 Merck Patent Gmbh, 6100 Darmstadt Isoflavane und Isoflavene und Verfahren zu Ihrer Herstellung sowie diese enthaltende Arzneimittel
DE1543749A1 (de) * 1966-02-16 1969-12-11 Merck Ag E Verfahren zur Herstellung von 3,4-cis-4-Aryl-isoflavanen
JPS54734B2 (bg) 1973-05-14 1979-01-16
US3973608A (en) * 1973-08-01 1976-08-10 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Microbial production of certain isoflavones
US3886278A (en) * 1973-08-22 1975-05-27 Mead Johnson & Co Ammonium carboxylate sebum inhibition process
US4061779A (en) * 1973-09-11 1977-12-06 Beecham Group Limited Naphthalene derivatives having anti-inflammatory activity
JPS576427B2 (bg) 1974-01-25 1982-02-04
HU168753B (bg) 1974-05-03 1976-07-28
JPS50160483A (bg) 1974-06-19 1975-12-25
GB1495189A (en) 1975-09-12 1977-12-14 Pfizer Ltd 4-oxo-4h-benzopyran derivatives and process for their preparation
DE2643800C2 (de) * 1976-09-29 1986-10-30 Fritz Werner Industrie-Ausrüstungen GmbH, 6222 Geisenheim Verfahren zur Herstellung von Xylose durch enzymatische Hydrolyse von Xylanen
US4264509A (en) * 1977-06-08 1981-04-28 Z-L Limited Partnership Isoflavones and related compounds, methods of preparing and using and antioxidant compositions containing same
US4157984A (en) * 1977-06-08 1979-06-12 Z-L Limited Antioxidants, antioxidant compositions and methods of preparing and using same
SU907060A1 (ru) * 1979-02-07 1982-02-23 Всесоюзный Научно-Исследовательский Биотехнический Институт Способ получени розового масла
US4390559A (en) 1979-04-11 1983-06-28 Z-L Limited Partnership Isoflavones and related compounds, methods of preparing and using and antioxidant compositions containing same
US4366082A (en) * 1979-04-11 1982-12-28 Z-L Limited Partnership Isoflavones and related compounds, methods of preparing and using and antioxidant compositions containing same
JPS5933232A (ja) * 1982-08-19 1984-02-23 Tokiwa Kanpou Seiyaku:Kk マメ科植物からサポニン類およびフラボン類の分離方法
JPS59199630A (ja) 1983-04-26 1984-11-12 Takeda Chem Ind Ltd 卵巣機能低下症治療剤
JPS6048924A (ja) * 1983-08-24 1985-03-16 Takeda Chem Ind Ltd 骨粗鬆症治療剤
JPS6054379A (ja) 1983-09-05 1985-03-28 Takeda Chem Ind Ltd 新規4h−1−ベンゾピラン−4−オン誘導体,その製法および用途
JPS60132976A (ja) * 1983-12-21 1985-07-16 Takeda Chem Ind Ltd 新規3−フエニル−4h−1−ベンゾピラン−4−オン誘導体
US4484013A (en) * 1983-12-30 1984-11-20 Uop Inc. Process for coproduction of isopropanol and tertiary butyl alcohol
US4839281A (en) * 1985-04-17 1989-06-13 New England Medical Center Hospitals, Inc. Lactobacillus strains and methods of selection
JPS61247396A (ja) * 1985-04-24 1986-11-04 Yamanouchi Pharmaceut Co Ltd ゲニステインの製造法
JPS61246124A (ja) * 1985-04-24 1986-11-01 Yamanouchi Pharmaceut Co Ltd 制癌剤
JPS62106017A (ja) * 1985-11-01 1987-05-16 Yamanouchi Pharmaceut Co Ltd 抗腫瘍剤
JPS62106016A (ja) * 1985-11-01 1987-05-16 Yamanouchi Pharmaceut Co Ltd 免疫抑制剤
JPS62126186A (ja) 1985-11-28 1987-06-08 Tsumura Juntendo Inc イソフラボン誘導体含有溶液の製造方法
GB8626344D0 (en) 1986-11-04 1986-12-03 Zyma Sa Bicyclic compounds
JPS6442427A (en) 1987-08-10 1989-02-14 Tsumura & Co Sialidase inhibitor
JPH0832632B2 (ja) 1988-03-08 1996-03-29 株式会社太田胃散 尿素窒素代謝改善剤
JPH0714927B2 (ja) 1988-04-06 1995-02-22 キッコーマン株式会社 イソフラボン化合物の製造法
US4950475A (en) * 1988-07-19 1990-08-21 Imaginative Research Associates, Inc. Novel film-forming gels with high concentrations of humectants and emollients
JPH0267218A (ja) * 1988-08-31 1990-03-07 Nagakura Seiyaku Kk ウイルス・ゲノム不活化剤
JPH0269165A (ja) 1988-09-02 1990-03-08 Mitsugi Ohashi 癌抑制食品
JPH02124883A (ja) 1988-11-04 1990-05-14 Kitasato Inst:The 抗酸化作用を有するイソフラボン誘導体およびその製造法
JP2753719B2 (ja) 1988-12-15 1998-05-20 日本油脂株式会社 リポソーム製剤の製造法
JPH02193919A (ja) * 1989-01-23 1990-07-31 Kao Corp 皮脂線抑制剤
JPH0347049A (ja) 1989-03-09 1991-02-28 Sanyu:Kk 豆腐廃液ゆからの食品素材及び健康飲料の製造方法
US5153230A (en) 1989-10-06 1992-10-06 Perfective Cosmetics, Inc. Topical skin cream composition
CH679584A5 (bg) 1989-11-10 1992-03-13 Nestle Sa
IT1241079B (it) 1990-03-23 1993-12-29 Chiesi Farma Spa Composizioni farmaceutiche contenenti ipriflavone,procedimento per la loro preparazione e relativo impiego terapeutico
JPH089610B2 (ja) * 1990-04-06 1996-01-31 キノイン・ジョージセル・エーシュ・ヴェジェーセティ・テルメーケク・ジャーラ・エルテー 置換イソフラボン誘導体の改良された製造方法
US5489524A (en) * 1991-03-26 1996-02-06 The United States Of America As Represented By The Department Of Health And Human Services Chimeric protein that has a human Rho motif and deoxyribonuclease activity
JP2799254B2 (ja) * 1991-07-11 1998-09-17 三菱電機株式会社 半導体装置の製造方法
JPH0517056A (ja) * 1991-07-12 1993-01-26 Ricoh Co Ltd ロール紙カセツト
GB2261671B (en) * 1991-11-16 1996-07-03 Gb Biotech Gel production from plant matter
JPH05170756A (ja) 1991-12-20 1993-07-09 Kikkoman Corp イソフラボン化合物の製造法
ATE275959T1 (de) 1992-05-19 2004-10-15 Graham Edmund Kelly Verwendung von isoflavon phyto-östrogen extrakten von soja oder klee
JP3241440B2 (ja) * 1992-07-02 2001-12-25 有限会社野々川商事 化粧料
FR2693724B1 (fr) 1992-07-17 1994-10-07 Lipha Utilisation de composés benzopyraniques ou benzothiopyraniques pour l'induction de l'expression des gènes de la nodulation des bactéries du genre Rhizobium associées aux légumineuses.
JPH0640876A (ja) 1992-07-23 1994-02-15 Kobe Steel Ltd 紫外線障害防御外用剤
JPH0640909A (ja) 1992-07-23 1994-02-15 Kobe Steel Ltd スーパーオキシド・ディスムターゼ様活性剤
JPH0686682A (ja) 1992-07-23 1994-03-29 Kobe Steel Ltd 4’,7,8−トリヒドロキシイソフラボンの製造方法
DE4236237A1 (de) * 1992-10-27 1994-04-28 Behringwerke Ag Prodrugs, ihre Herstellung und Verwendung als Arzneimittel
WO1994023716A1 (en) * 1993-04-16 1994-10-27 Tufts University School Of Medicine Method for treatment of menopausal and premenstrual symptoms
JPH06321752A (ja) 1993-05-07 1994-11-22 Kao Corp 美白剤
US5595970A (en) * 1993-07-16 1997-01-21 Schering Aktiengesellschaft Treatment of climacteric disorders with nitric oxide synthase substrates and/or donors
US5637561A (en) * 1993-10-12 1997-06-10 Protein Technologies International, Inc. Aglucone isoflavone enriched vegetable protein whey, whey protein, and process for producing
US5320949A (en) * 1993-10-12 1994-06-14 Protein Technologies International, Inc. Process for producing aglucone isoflavone enriched vegetable protein fiber
CN1055932C (zh) * 1993-10-12 2000-08-30 蛋白质技术国际公司 葡糖苷配基异黄酮富集的植物蛋白提取物和分离物及生产方法
US5589182A (en) * 1993-12-06 1996-12-31 Tashiro; Renki Compositions and method of treating cardio-, cerebro-vascular and alzheimer's diseases and depression
JP3078694B2 (ja) * 1993-12-17 2000-08-21 キッコーマン株式会社 ゲニステインの製造法
IL112061A (en) * 1994-01-13 1999-10-28 Bristol Myers Squibb Co Methods for the preparation of taxanes
US6369103B1 (en) 1994-01-18 2002-04-09 Bristol-Myers Squibb Company Method for preventing or reducing risk of onset of cardiovascular events employing an HMG CoA reductase inhibitor
IL112639A0 (en) 1994-03-11 1995-05-26 Bristol Myers Squibb Co A pharmaceutical composition containing pravastin
US5506211A (en) * 1994-05-09 1996-04-09 The Uab Research Foundation Genistein for use in inhibiting osteroclasts
US5424331A (en) * 1994-06-10 1995-06-13 Bio-Virus Research Incorporated Pharmaceutical compositions and dietary soybean food products for the prevention of osteoporosis
US5547866A (en) 1994-07-20 1996-08-20 The Regents Of The University Of California Taxane production in haploid-derived cell cultures
DE4432947C2 (de) * 1994-09-16 1998-04-09 New Standard Gmbh Mittel zur Behandlung der Haut und seine Verwendung
AU3689095A (en) * 1994-10-03 1996-04-26 Schouten Industries B.V. Food and health products
US5637598A (en) * 1994-11-18 1997-06-10 Eli Lilly And Company Methods of inhibiting bone loss
US5516528A (en) * 1995-01-13 1996-05-14 Wake Forest University Dietary phytoestrogen in estrogen replacement therapy
US5523087A (en) 1995-02-15 1996-06-04 Bio-Virus Research Incorporated Pharmaceutical compositions for the treatment of diabetic male sexual dysfunction
US5569459A (en) * 1995-02-15 1996-10-29 Bio-Virus Research Incorporated Pharmaceutical compositions for the management of premenstrual syndrome and alleviation of menopausal disorders
US5679806A (en) * 1995-02-24 1997-10-21 Hauser, Inc. Process for the isolation and purification of isoflavones
JPH08283283A (ja) * 1995-04-14 1996-10-29 Kikkoman Corp マロニルイソフラボン配糖体及び該物質からイソフラボン配糖体又はイソフラボンアグリコンを取得する方法
EP0873142A4 (en) * 1995-06-07 2001-08-08 Sugen Inc CONNECTION TESTING TESTS
AU5970496A (en) * 1995-06-07 1996-12-30 Patrick C. Kung Compounds and methods for promoting hair growth
US5639785A (en) * 1995-06-07 1997-06-17 Global Pharma, Ltd. Methods for the treatment of baldness and gray hair using isoflavonoid derivatives
US5554519A (en) * 1995-08-07 1996-09-10 Fermalogic, Inc. Process of preparing genistein
JPH0967362A (ja) 1995-09-01 1997-03-11 Sankyo Co Ltd 5α−還元酵素阻害剤ビスイソフラボン類
US6261565B1 (en) * 1996-03-13 2001-07-17 Archer Daniels Midland Company Method of preparing and using isoflavones
US5702752A (en) 1996-03-13 1997-12-30 Archer Daniels Midland Company Production of isoflavone enriched fractions from soy protein extracts
US5821361A (en) 1996-06-11 1998-10-13 Protein Technologies International, Inc. Recovery of isoflavones from soy molasses
JPH1059956A (ja) 1996-08-22 1998-03-03 Kikkoman Corp 新規イソフラボン誘導体及びその製造法
AUPO203996A0 (en) * 1996-08-30 1996-09-26 Novogen Research Pty Ltd Therapeutic uses
US5726034A (en) * 1996-09-06 1998-03-10 Protein Technologies International, Inc. Aglucone isoflavone enriched vegetable protein extract and protein material, and high genistein and daidzein content materials and process for producing the same
US5804234A (en) * 1996-09-13 1998-09-08 Suh; John D. Plant protein for nutritional products and method of making same
US5733926A (en) * 1996-12-13 1998-03-31 Gorbach; Sherwood L. Isoflavonoids for treatment and prevention of alzheimer dementia and reduced cognitive functions
US6146668A (en) 1997-04-28 2000-11-14 Novogen, Inc. Preparation of isoflavones from legumes
WO1998050026A1 (en) 1997-05-01 1998-11-12 Novogen Inc Treatment or prevention of menopausal symptoms and osteoporosis
US6060070A (en) 1997-06-11 2000-05-09 Gorbach; Sherwood L. Isoflavonoids for treatment and prevention of aging skin and wrinkles
US5855892A (en) * 1997-09-19 1999-01-05 Potter; Susan M. Method for decreasing LDL-cholesterol concentration and increasing HDL-cholesterol concentration in the blood to reduce the risk of atherosclerosis and vascular disease
US5942539A (en) * 1997-10-03 1999-08-24 Wake Forest University Methods of treating or preventing endometriosis with phytoestrogens
AUPP112497A0 (en) 1997-12-24 1998-01-22 Novogen Research Pty Ltd Compositions and method for protecting skin from UV induced immunosupression and skin damage
US6004558A (en) 1998-02-25 1999-12-21 Novogen, Inc. Methods for treating cancer with legume plant extracts
US6132795A (en) 1998-03-15 2000-10-17 Protein Technologies International, Inc. Vegetable protein composition containing an isoflavone depleted vegetable protein material with an isoflavone containing material
WO1999047119A1 (en) 1998-03-16 1999-09-23 The Procter & Gamble Company Methods for regulating skin appearance
AUPP260798A0 (en) 1998-03-26 1998-04-23 Novogen Research Pty Ltd Treatment of medical related conditions with isoflavone containing extracts of clover
US6544566B1 (en) 1999-04-23 2003-04-08 Protein Technologies International, Inc. Composition containing plant sterol, soy protein and isoflavone for reducing LDL cholesterol

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US7915308B2 (en) 2011-03-29
GB2331015B (en) 2001-05-09
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CA2265049A1 (en) 1998-03-05
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US20080287528A1 (en) 2008-11-20
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