FI105485B - Transferriini-polykationi-konjugaatit ja nukleiinihappokompleksit - Google Patents

Transferriini-polykationi-konjugaatit ja nukleiinihappokompleksit Download PDF

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Publication number
FI105485B
FI105485B FI901297A FI901297A FI105485B FI 105485 B FI105485 B FI 105485B FI 901297 A FI901297 A FI 901297A FI 901297 A FI901297 A FI 901297A FI 105485 B FI105485 B FI 105485B
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FI
Finland
Prior art keywords
transferrin
nucleic acid
polycation
cells
dna
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Application number
FI901297A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI901297A0 (fi
Inventor
Ernst Wagner
Max L Birnstiel
Hartmut Beug
Matthew Cotten
Original Assignee
Boehringer Ingelheim Int
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Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of FI901297A0 publication Critical patent/FI901297A0/fi
Application granted granted Critical
Publication of FI105485B publication Critical patent/FI105485B/fi

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
FI901297A 1989-03-16 1990-03-15 Transferriini-polykationi-konjugaatit ja nukleiinihappokompleksit FI105485B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT61089 1989-03-16
AT61089 1989-03-16

Publications (2)

Publication Number Publication Date
FI901297A0 FI901297A0 (fi) 1990-03-15
FI105485B true FI105485B (fi) 2000-08-31

Family

ID=3495147

Family Applications (1)

Application Number Title Priority Date Filing Date
FI901297A FI105485B (fi) 1989-03-16 1990-03-15 Transferriini-polykationi-konjugaatit ja nukleiinihappokompleksit

Country Status (20)

Country Link
US (2) US5354844A (fr)
EP (1) EP0388758B1 (fr)
JP (1) JP3138461B2 (fr)
KR (1) KR0178022B1 (fr)
AT (1) ATE195144T1 (fr)
AU (1) AU637085B2 (fr)
CA (1) CA2012311C (fr)
DD (1) DD297842A5 (fr)
DE (1) DE59010910D1 (fr)
DK (1) DK0388758T3 (fr)
ES (1) ES2148136T3 (fr)
FI (1) FI105485B (fr)
GR (1) GR3034717T3 (fr)
HU (2) HU218716B (fr)
IL (1) IL93755A (fr)
NO (1) NO301932B1 (fr)
NZ (1) NZ232918A (fr)
PT (1) PT93441B (fr)
RU (2) RU2098487C1 (fr)
ZA (1) ZA901974B (fr)

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