MX358603B - Tratamiento de enfermedades relacionadas con un gen supresor de tumor mediante inhibicion del transcrito antisentido natural para el gen. - Google Patents

Tratamiento de enfermedades relacionadas con un gen supresor de tumor mediante inhibicion del transcrito antisentido natural para el gen.

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Publication number
MX358603B
MX358603B MX2015009333A MX2015009333A MX358603B MX 358603 B MX358603 B MX 358603B MX 2015009333 A MX2015009333 A MX 2015009333A MX 2015009333 A MX2015009333 A MX 2015009333A MX 358603 B MX358603 B MX 358603B
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MX
Mexico
Prior art keywords
tumor suppressor
gene
inhibition
treatment
related diseases
Prior art date
Application number
MX2015009333A
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English (en)
Inventor
Collard Joseph
Khorkova Sherman Olga
Original Assignee
Curna Inc
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Filing date
Publication date
Application filed by Curna Inc filed Critical Curna Inc
Publication of MX358603B publication Critical patent/MX358603B/es

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Abstract

La presente invención se refiere a oligonucleótidos antisentido que modulan la expresión de y/o la función de genes supresores de tumor, en particular al dirigir polinucleótidos antisentido naturales de los genes supresores de tumor. La invención también se relaciona con la identificación de estos oligonucleótidos antisentido y su uso en el tratamiento de enfermedades y trastornos asociados con la expresión de genes supresores de tumor.
MX2015009333A 2008-12-04 2009-12-03 Tratamiento de enfermedades relacionadas con un gen supresor de tumor mediante inhibicion del transcrito antisentido natural para el gen. MX358603B (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11997308P 2008-12-04 2008-12-04
US15459409P 2009-02-23 2009-02-23
US15724909P 2009-03-04 2009-03-04
US16638109P 2009-04-03 2009-04-03
PCT/US2009/066654 WO2010065787A2 (en) 2008-12-04 2009-12-03 Treatment of tumor suppressor gene related diseases by inhibition of natural antisense transcript to the gene

Publications (1)

Publication Number Publication Date
MX358603B true MX358603B (es) 2018-08-28

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Family Applications (2)

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MX2011005918A MX2011005918A (es) 2008-12-04 2009-12-03 Tratamiento de enfermedades relacionadas con un gen supresor de tumor mediante inhibicion del transcrito antisentido natural para el gen.
MX2015009333A MX358603B (es) 2008-12-04 2009-12-03 Tratamiento de enfermedades relacionadas con un gen supresor de tumor mediante inhibicion del transcrito antisentido natural para el gen.

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US (3) US20110294870A1 (es)
EP (1) EP2370582B1 (es)
JP (3) JP5923306B2 (es)
KR (3) KR101866152B1 (es)
CN (2) CN107338251A (es)
CA (1) CA2745811C (es)
ES (1) ES2637063T3 (es)
MX (2) MX2011005918A (es)
RU (2) RU2746478C2 (es)
WO (1) WO2010065787A2 (es)

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KR101866152B1 (ko) 2008-12-04 2018-06-08 큐알엔에이, 인크. 종양 억제 유전자에 대한 천연 안티센스 전사체의 억제에 의해 종양 억제 유전자 관련된 질환의 치료
KR101829469B1 (ko) 2008-12-04 2018-03-30 큐알엔에이, 인크. Ｅｐｏ에 대한 천연 안티센스 전사체의 억제에 의해 에리트로포에틴(ｅｐｏ) 관련된 질환의 치료
CN102791862B (zh) * 2009-12-31 2017-04-05 库尔纳公司 通过抑制胰岛素受体底物2(irs2)和转录因子e3(tfe3)的天然反义转录物而治疗irs2相关疾病
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