ES2986067T3 - Moléculas de anticuerpos frente a PD-1 y usos de las mismas - Google Patents
Moléculas de anticuerpos frente a PD-1 y usos de las mismas Download PDFInfo
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- ES2986067T3 ES2986067T3 ES16831788T ES16831788T ES2986067T3 ES 2986067 T3 ES2986067 T3 ES 2986067T3 ES 16831788 T ES16831788 T ES 16831788T ES 16831788 T ES16831788 T ES 16831788T ES 2986067 T3 ES2986067 T3 ES 2986067T3
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- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
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Landscapes
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Applications Claiming Priority (10)
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| US201562269044P | 2015-12-17 | 2015-12-17 | |
| US201662331371P | 2016-05-03 | 2016-05-03 | |
| US201662344784P | 2016-06-02 | 2016-06-02 | |
| US201662347331P | 2016-06-08 | 2016-06-08 | |
| US201662359781P | 2016-07-08 | 2016-07-08 | |
| US201662381384P | 2016-08-30 | 2016-08-30 | |
| US201662400787P | 2016-09-28 | 2016-09-28 | |
| US201662414128P | 2016-10-28 | 2016-10-28 | |
| US201662431846P | 2016-12-09 | 2016-12-09 | |
| PCT/US2016/067200 WO2017106656A1 (en) | 2015-12-17 | 2016-12-16 | Antibody molecules to pd-1 and uses thereof |
Publications (1)
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| ES2986067T3 true ES2986067T3 (es) | 2024-11-08 |
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| ES16831788T Active ES2986067T3 (es) | 2015-12-17 | 2016-12-16 | Moléculas de anticuerpos frente a PD-1 y usos de las mismas |
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| EP (2) | EP4424322A3 (enExample) |
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| AU (1) | AU2016369537B2 (enExample) |
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| MX (1) | MX2018007423A (enExample) |
| PH (1) | PH12018501206A1 (enExample) |
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| US10570204B2 (en) | 2013-09-26 | 2020-02-25 | The Medical College Of Wisconsin, Inc. | Methods for treating hematologic cancers |
| JOP20200094A1 (ar) | 2014-01-24 | 2017-06-16 | Dana Farber Cancer Inst Inc | جزيئات جسم مضاد لـ pd-1 واستخداماتها |
| CA2974651A1 (en) | 2014-01-24 | 2015-07-30 | Children's Hospital Of Eastern Ontario Research Institute Inc. | Smc combination therapy for the treatment of cancer |
| JOP20200096A1 (ar) | 2014-01-31 | 2017-06-16 | Children’S Medical Center Corp | جزيئات جسم مضاد لـ tim-3 واستخداماتها |
| EP3660050A1 (en) | 2014-03-14 | 2020-06-03 | Novartis AG | Antibody molecules to lag-3 and uses thereof |
| KR20170060042A (ko) | 2014-09-13 | 2017-05-31 | 노파르티스 아게 | Alk 억제제의 조합 요법 |
| CN114920840A (zh) | 2014-10-14 | 2022-08-19 | 诺华股份有限公司 | 针对pd-l1的抗体分子及其用途 |
| BR112018000768A2 (pt) | 2015-07-13 | 2018-09-25 | Cytomx Therapeutics Inc | anticorpos anti-pd-1, anticorpos anti-pd-1 ativáveis e métodos de uso dos mesmos |
| WO2017013421A1 (en) * | 2015-07-20 | 2017-01-26 | Virttu Biologics Limited | Treatment of cancer by infusion of oncolytic herpes simplex virus to the blood |
| EP3328407A1 (en) * | 2015-07-29 | 2018-06-06 | Novartis AG | Combination of pd-1 antagonist with an egfr inhibitor |
| KR102220275B1 (ko) | 2015-11-18 | 2021-02-26 | 머크 샤프 앤드 돔 코포레이션 | Pd1 및/또는 lag3 결합제 |
| CA3007421A1 (en) * | 2015-12-17 | 2017-06-22 | Novartis Ag | Combination of c-met inhibitor with antibody molecule to pd-1 and uses thereof |
| WO2017143449A1 (en) * | 2016-02-24 | 2017-08-31 | Children's Hospital Of Eastern Ontario Research Institute Inc. | Smc combination therapy for the treatment of cancer |
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Hdac抑制劑與pd-l1抑制劑之組合治療 |
| EP3484518B1 (en) | 2016-07-07 | 2024-08-14 | The Board of Trustees of the Leland Stanford Junior University | Antibody adjuvant conjugates |
| CN110740748A (zh) * | 2017-01-17 | 2020-01-31 | 芝加哥大学 | 肿瘤微环境中功能障碍的抗原特异性cd8+t细胞 |
| BR112019017628A2 (pt) | 2017-02-24 | 2020-07-07 | Macrogenics, Inc. | molécula de ligação a cd137 x ta, composições farmacêuticas, uso da molécula de ligação a cd137 x ta, molécula de ligação a cd137, uso da molécula de ligação a cd137, molécula de ligação a her2/neu, uso da molécula de ligação a her2/neu, e uso de uma composição |
| WO2018209270A1 (en) | 2017-05-11 | 2018-11-15 | Northwestern University | Adoptive cell therapy using spherical nucleic acids (snas) |
| CN111163798A (zh) * | 2017-07-20 | 2020-05-15 | 诺华股份有限公司 | 用于抗lag-3抗体的给药方案及其用途 |
| WO2019018640A1 (en) * | 2017-07-21 | 2019-01-24 | Novartis Ag | POSOLOGICAL REGIMES FOR ANTI-GITREN ANTIBODIES AND USES THEREOF |
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| WO2019027857A1 (en) * | 2017-08-04 | 2019-02-07 | Merck Sharp & Dohme Corp. | COMBINATIONS OF PD-1 ANTAGONISTS AND STING BENZO [B] THIOPHENIC AGONISTS FOR THE TREATMENT OF CANCER |
| WO2019036855A1 (en) | 2017-08-21 | 2019-02-28 | Adagene Inc. | Anti-cd137 molecules and use thereof |
| KR20240138135A (ko) | 2017-08-25 | 2024-09-20 | 파이브 프라임 테라퓨틱스, 인크. | B7-h4 항체 및 그의 사용 방법 |
| WO2019104716A1 (en) * | 2017-12-01 | 2019-06-06 | Adagene Inc. | Methods for using cd137 ligand as biomarker for treatment with anti-cd137 antibody |
| WO2019122941A1 (en) * | 2017-12-21 | 2019-06-27 | Debiopharm International Sa | Combination anti cancer therapy with an iap antagonist and an anti pd-1 molecule |
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| MA51844A (fr) * | 2018-02-13 | 2021-05-19 | Merck Sharp & Dohme | Méthodes de traitement du cancer avec des anticorps anti pd-1 et des anticorps anti ctla4 |
| BR112020016331A8 (pt) | 2018-02-13 | 2023-02-07 | Merck Sharp & Dohme | Métodos para tratar câncer com anticorpos anti-pd-1 |
| KR20200123170A (ko) | 2018-02-21 | 2020-10-28 | 파이브 프라임 테라퓨틱스, 인크. | B7-h4 항체 제형 |
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| BR112020022265A2 (pt) | 2018-05-07 | 2021-02-23 | Genmab A/S | método para tratar câncer em um indivíduo, e, estojo. |
| AU2019270277B9 (en) * | 2018-05-15 | 2024-12-05 | Innate Pharma | Treatment of cancer |
| EP4349411A3 (en) | 2018-06-20 | 2024-06-19 | Incyte Corporation | Anti-pd-1 antibodies and uses thereof |
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- 2016-12-16 JP JP2018531392A patent/JP2019503349A/ja active Pending
- 2016-12-16 KR KR1020187019916A patent/KR102833068B1/ko active Active
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| CA3007671A1 (en) | 2017-06-22 |
| IL259987A (en) | 2018-07-31 |
| MX2018007423A (es) | 2018-11-09 |
| KR102833068B1 (ko) | 2025-07-14 |
| AU2016369537A1 (en) | 2018-06-28 |
| PH12018501206A1 (en) | 2019-02-11 |
| JP2020143149A (ja) | 2020-09-10 |
| EP4424322A2 (en) | 2024-09-04 |
| US20180371093A1 (en) | 2018-12-27 |
| EP3389712B1 (en) | 2024-04-10 |
| KR20180088907A (ko) | 2018-08-07 |
| EP4424322A3 (en) | 2025-04-16 |
| RU2018125773A (ru) | 2020-01-21 |
| CL2018001560A1 (es) | 2018-07-27 |
| JP7569166B2 (ja) | 2024-10-17 |
| JP2019503349A (ja) | 2019-02-07 |
| EP3389712A1 (en) | 2018-10-24 |
| CN108495651A (zh) | 2018-09-04 |
| WO2017106656A8 (en) | 2018-06-28 |
| WO2017106656A1 (en) | 2017-06-22 |
| RU2018125773A3 (enExample) | 2020-05-15 |
| AU2016369537B2 (en) | 2024-03-14 |
| BR112018012138A2 (pt) | 2018-12-04 |
| JP2024174916A (ja) | 2024-12-17 |
| JP2022180567A (ja) | 2022-12-06 |
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