EA200601761A1 - Композиции в качестве адъювантов для усиления иммунных ответов на вакцины и способы их применения - Google Patents

Композиции в качестве адъювантов для усиления иммунных ответов на вакцины и способы их применения

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EA200601761A1
EA200601761A1 EA200601761A EA200601761A EA200601761A1 EA 200601761 A1 EA200601761 A1 EA 200601761A1 EA 200601761 A EA200601761 A EA 200601761A EA 200601761 A EA200601761 A EA 200601761A EA 200601761 A1 EA200601761 A1 EA 200601761A1
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Eurasian Patent Office
Prior art keywords
tim
compositions
targeting molecule
provides
methods
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EA200601761A
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English (en)
Inventor
Уилльям Соо Хоо
Эрик Р. Дженсен
Томас Молль
Деннис Дж. Карло
Брайан К. Хелмич
Сунпинь Йей
Джаянт Тхатте
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Телос Фармасьютикалз, Инк.
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Application filed by Телос Фармасьютикалз, Инк. filed Critical Телос Фармасьютикалз, Инк.
Publication of EA200601761A1 publication Critical patent/EA200601761A1/ru

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Abstract

Изобретение представляет композиции, содержащие антиген и TIM-нацеливающую молекулу. Кроме того, изобретение обеспечивает конъюгат TIM-нацеливающей молекулы, например, TIM-нацеливающей молекулы, конъюгированной с терапевтическим или диагностическим фрагментом. Дополнительно изобретение предусматривает способы применения таких композиций. В одном воплощении, изобретение обеспечивает способ стимулирования иммунного ответа у индивидуума введением композиции, содержащей антиген и TIM-нацеливающую молекулу в фармацевтически приемлемом носителе. В другом воплощении, изобретение обеспечивает способ стимуляции иммунного ответа у индивидуума введением антигена и TIM-нацеливающей молекулы, которые можно вводить вместе в одной композиции или раздельно.
EA200601761A 2004-03-24 2005-03-22 Композиции в качестве адъювантов для усиления иммунных ответов на вакцины и способы их применения EA200601761A1 (ru)

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PCT/US2005/009480 WO2005097211A2 (en) 2004-03-24 2005-03-22 Compositions as adjuvants to improve immune responses to vaccines and methods of use

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