DK3178818T3 - Pyrazolylquinoxalinkinasehæmmere - Google Patents

Pyrazolylquinoxalinkinasehæmmere Download PDF

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Publication number
DK3178818T3
DK3178818T3 DK16207610.3T DK16207610T DK3178818T3 DK 3178818 T3 DK3178818 T3 DK 3178818T3 DK 16207610 T DK16207610 T DK 16207610T DK 3178818 T3 DK3178818 T3 DK 3178818T3
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Prior art keywords
pyrazolylquinoxalinkinase
inhibitors
pyrazolylquinoxalinkinase inhibitors
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DK16207610.3T
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Danish (da)
English (en)
Inventor
Christopher William Murray
Valerio Berdini
Gilbert Ebai Besong
Christopher Charles Frederick Hamlett
Christopher Norbert Johnson
Steven John Woodhead
Michael Reader
David Charles Rees
Werner Constant Johan Embrechts
Rhalid Akkari
Lieven Meerpoel
Gordon Saxty
Laurence Anne Mevellec
Patrick René Angibaud
Eddy Jean Edgard Freyne
Tom Cornelis Hortense Govaerts
Johan Erwin Edmond Weerts
Timothy Pietro Suren Perera
Ronaldus Arnodus Hendrika Joseph Gilissen
Berthold Wroblowski
Jean Fernand Armand Lacrampe
Olivier Alexis Georges Querolle
Elisabeth Thérèse Jeanne Pasquier
Pascal Ghislain André Bonnet
Alexandra Papanikos
Isabelle Noã«Lle Constance Pilatte
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Astex Therapeutics Ltd
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Publication of DK3178818T3 publication Critical patent/DK3178818T3/da

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    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • Epidemiology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
DK16207610.3T 2010-04-30 2011-04-28 Pyrazolylquinoxalinkinasehæmmere DK3178818T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32988410P 2010-04-30 2010-04-30
GB201007286A GB201007286D0 (en) 2010-04-30 2010-04-30 New compounds
EP11724710.6A EP2563775B1 (en) 2010-04-30 2011-04-28 Pyrazolyl quinoxaline kinase inhibitors

Publications (1)

Publication Number Publication Date
DK3178818T3 true DK3178818T3 (da) 2019-07-22

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ID=42289929

Family Applications (3)

Application Number Title Priority Date Filing Date
DK16207610.3T DK3178818T3 (da) 2010-04-30 2011-04-28 Pyrazolylquinoxalinkinasehæmmere
DK11724710.6T DK2563775T3 (en) 2010-04-30 2011-04-28 PYRAZOLYLQUINOXALINKINASE INHIBITORS
DK19175481.1T DK3590934T3 (da) 2010-04-30 2011-04-28 Pyrazolylquinoxalinkinasehæmmere

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK11724710.6T DK2563775T3 (en) 2010-04-30 2011-04-28 PYRAZOLYLQUINOXALINKINASE INHIBITORS
DK19175481.1T DK3590934T3 (da) 2010-04-30 2011-04-28 Pyrazolylquinoxalinkinasehæmmere

Country Status (41)

Country Link
US (6) US8895601B2 (enExample)
EP (3) EP3178818B1 (enExample)
JP (1) JP5639261B2 (enExample)
KR (2) KR101889565B1 (enExample)
CN (2) CN104725362B (enExample)
AP (1) AP3210A (enExample)
AR (1) AR080982A1 (enExample)
AU (2) AU2011247047B2 (enExample)
BR (1) BR112012027509B1 (enExample)
CA (1) CA2796204C (enExample)
CL (1) CL2012003048A1 (enExample)
CR (2) CR20180339A (enExample)
CY (2) CY1121882T1 (enExample)
DK (3) DK3178818T3 (enExample)
EA (2) EA023222B8 (enExample)
EC (1) ECSP12012318A (enExample)
ES (3) ES2899937T3 (enExample)
FI (1) FIC20250009I1 (enExample)
FR (1) FR25C1006I1 (enExample)
GB (1) GB201007286D0 (enExample)
HR (1) HRP20211675T1 (enExample)
HU (4) HUE045893T2 (enExample)
IL (1) IL222600A (enExample)
IN (1) IN2012MN02591A (enExample)
JO (1) JO3366B1 (enExample)
LT (4) LT3178818T (enExample)
ME (1) ME01825B (enExample)
MX (2) MX2012012414A (enExample)
MY (2) MY189427A (enExample)
NL (1) NL301318I2 (enExample)
NO (1) NO2025011I1 (enExample)
NZ (1) NZ602726A (enExample)
PH (1) PH12012501993A1 (enExample)
PL (3) PL3590934T3 (enExample)
PT (3) PT2563775T (enExample)
RS (3) RS55863B1 (enExample)
SG (2) SG10201708578QA (enExample)
SI (3) SI2563775T1 (enExample)
SM (3) SMT201900469T1 (enExample)
TW (1) TWI545122B (enExample)
WO (1) WO2011135376A1 (enExample)

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CN107252429B (zh) 2009-04-22 2023-06-16 雷斯韦洛吉克斯公司 新抗炎剂
GB201007286D0 (en) 2010-04-30 2010-06-16 Astex Therapeutics Ltd New compounds
GB201020179D0 (en) 2010-11-29 2011-01-12 Astex Therapeutics Ltd New compounds
US8754114B2 (en) 2010-12-22 2014-06-17 Incyte Corporation Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
GB201118675D0 (en) 2011-10-28 2011-12-14 Astex Therapeutics Ltd New compounds
GB201118654D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201118656D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201118652D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201209613D0 (en) 2012-05-30 2012-07-11 Astex Therapeutics Ltd New compounds
GB201209609D0 (en) 2012-05-30 2012-07-11 Astex Therapeutics Ltd New compounds
PE20190736A1 (es) 2012-06-13 2019-05-23 Incyte Holdings Corp Compuestos triciclicos sustituidos como inhibidores del receptor del factor de crecimiento de fibroblastos (fgfr)
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MX338885B (es) * 2012-10-15 2016-05-04 Resverlogix Corp Compuestos utiles en la sintesis de compuestos de benzamida.
EP4223770A3 (en) 2012-11-05 2023-10-18 Foundation Medicine, Inc. Novel fusion molecules and uses thereof
HK1214830A1 (zh) 2012-11-05 2016-08-05 Foundation Medicine, Inc. 新型ntrk1融合分子及其应用
WO2014085486A2 (en) 2012-11-30 2014-06-05 Waters Technologies Corporation Methods and apparatus for the analysis of vitamin d metabolites
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