DK165455C - Analogifremgangsmaade til fremstilling af dipeptidderivater og farmaceutisk acceptable salte heraf - Google Patents

Analogifremgangsmaade til fremstilling af dipeptidderivater og farmaceutisk acceptable salte heraf

Info

Publication number
DK165455C
DK165455C DK523579A DK523579A DK165455C DK 165455 C DK165455 C DK 165455C DK 523579 A DK523579 A DK 523579A DK 523579 A DK523579 A DK 523579A DK 165455 C DK165455 C DK 165455C
Authority
DK
Denmark
Prior art keywords
analogue
preparation
acceptable salts
pharmaceutical acceptable
dipeptide derivatives
Prior art date
Application number
DK523579A
Other languages
English (en)
Other versions
DK523579A (da
DK165455B (da
Inventor
Arthur A Patchett
Elbert E Harris
Matthew J Wyvratt
Edward W Tristram
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25513965&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK165455(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK523579A publication Critical patent/DK523579A/da
Publication of DK165455B publication Critical patent/DK165455B/da
Application granted granted Critical
Publication of DK165455C publication Critical patent/DK165455C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/80—Antihypertensive peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
DK523579A 1978-12-11 1979-12-10 Analogifremgangsmaade til fremstilling af dipeptidderivater og farmaceutisk acceptable salte heraf DK165455C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96824978A 1978-12-11 1978-12-11
US96824978 1978-12-11

Publications (3)

Publication Number Publication Date
DK523579A DK523579A (da) 1980-06-12
DK165455B DK165455B (da) 1992-11-30
DK165455C true DK165455C (da) 1993-04-13

Family

ID=25513965

Family Applications (1)

Application Number Title Priority Date Filing Date
DK523579A DK165455C (da) 1978-12-11 1979-12-10 Analogifremgangsmaade til fremstilling af dipeptidderivater og farmaceutisk acceptable salte heraf

Country Status (33)

Country Link
US (2) US4374829A (da)
EP (1) EP0012401B1 (da)
JP (3) JPS5581845A (da)
KR (3) KR850000847B1 (da)
AR (1) AR231971A1 (da)
AU (1) AU530380B2 (da)
BG (6) BG39293A3 (da)
CA (4) CA1302005C (da)
CS (1) CS237311B2 (da)
DD (1) DD148770A5 (da)
DE (2) DE19375005I2 (da)
DK (1) DK165455C (da)
EG (1) EG14182A (da)
ES (2) ES8101540A1 (da)
FI (1) FI68405C (da)
GR (1) GR72251B (da)
HK (1) HK27487A (da)
HU (1) HU182902B (da)
IE (1) IE48922B1 (da)
IL (1) IL58849A (da)
LU (1) LU90173I2 (da)
MA (1) MA18664A1 (da)
NL (4) NL930007I2 (da)
NO (3) NO151622C (da)
NZ (1) NZ192312A (da)
PH (1) PH24268A (da)
PL (2) PL131140B1 (da)
PT (1) PT70542A (da)
RO (4) RO85073B (da)
SU (1) SU1287756A3 (da)
YU (3) YU42655B (da)
ZA (1) ZA796688B (da)
ZW (1) ZW24479A1 (da)

Families Citing this family (386)

* Cited by examiner, † Cited by third party
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