DK163989C - Analogifremgangsmaade til fremstilling af beta-adrenergisk blokerende forbindelser og farmaceutisk acceptable salte deraf - Google Patents
Analogifremgangsmaade til fremstilling af beta-adrenergisk blokerende forbindelser og farmaceutisk acceptable salte derafInfo
- Publication number
- DK163989C DK163989C DK336682A DK336682A DK163989C DK 163989 C DK163989 C DK 163989C DK 336682 A DK336682 A DK 336682A DK 336682 A DK336682 A DK 336682A DK 163989 C DK163989 C DK 163989C
- Authority
- DK
- Denmark
- Prior art keywords
- addrenergic
- analogue
- beta
- preparation
- acceptable salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/211,341 US4405642A (en) | 1980-11-28 | 1980-11-28 | Method for treatment or prophylaxis of cardiac disorders |
| US21134180 | 1980-11-28 | ||
| US8101517 | 1981-11-16 | ||
| PCT/US1981/001517 WO1982001868A1 (en) | 1980-11-28 | 1981-11-16 | Method for treatment or prophylaxis of cardiac disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK336682A DK336682A (da) | 1982-07-28 |
| DK163989B DK163989B (da) | 1992-04-27 |
| DK163989C true DK163989C (da) | 1992-09-21 |
Family
ID=22786525
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK336682A DK163989C (da) | 1980-11-28 | 1982-07-28 | Analogifremgangsmaade til fremstilling af beta-adrenergisk blokerende forbindelser og farmaceutisk acceptable salte deraf |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4405642A (da) |
| EP (2) | EP0053436B1 (da) |
| JP (1) | JPS57502125A (da) |
| KR (1) | KR880001828B1 (da) |
| AU (1) | AU547994B2 (da) |
| CA (1) | CA1180344A (da) |
| DK (1) | DK163989C (da) |
| GR (1) | GR76922B (da) |
| IL (1) | IL64344A (da) |
| NZ (1) | NZ198871A (da) |
| PH (1) | PH18954A (da) |
| WO (1) | WO1982001868A1 (da) |
| ZA (1) | ZA817891B (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4604481A (en) * | 1980-11-28 | 1986-08-05 | American Hospital Supply Corporation | Compounds for treatment or prophylaxis of cardiac disorders |
| US4405642A (en) * | 1980-11-28 | 1983-09-20 | American Hospital Supply Corporation | Method for treatment or prophylaxis of cardiac disorders |
| US4402974A (en) * | 1981-06-23 | 1983-09-06 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
| US4798892A (en) * | 1981-11-12 | 1989-01-17 | E. I. Du Pont De Nemours And Company | 2-hydroxypropylamine heteroaryl ester derivatives |
| US4582855A (en) * | 1981-11-12 | 1986-04-15 | American Hospital Supply Corporation | Aromatic and esters of hydroxypropylamines |
| US4579867A (en) * | 1984-04-09 | 1986-04-01 | American Hospital Supply Corporation | Stable pharmaceutical compositions of short-acting β-adrenergic receptor blocking agents |
| DE3705384A1 (de) * | 1987-02-20 | 1988-09-01 | Goedecke Ag | 2-propylamin-derivate, verfahren zu deren herstellung sowie deren verwendung |
| US4897417A (en) * | 1988-12-15 | 1990-01-30 | E. I. Du Pont De Nemours & Co. | Prodrugs of 3,4-hydroxy benzoyloxypropanolamines |
| US4966914A (en) * | 1988-12-15 | 1990-10-30 | E. I. Du Pont De Nemours And Company | Oculoselective beta-blockers as antiglaucoma agents |
| US6750238B1 (en) | 2000-05-12 | 2004-06-15 | The University Of Toledo | Aralkyl ester soft drugs |
| US7049326B2 (en) * | 2000-05-12 | 2006-05-23 | The University Of Toledo | Method and compositions for temporarily incapacitating subjects |
| US6756047B2 (en) | 2000-05-12 | 2004-06-29 | The University Of Toledo | Method and compositions for treating persistent pulmonary hypertension using aralkyl ester soft drugs |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL75127C (da) * | 1943-10-05 | |||
| NL300886A (da) * | 1962-11-23 | |||
| NL301580A (da) * | 1962-12-11 | |||
| US3254112A (en) * | 1963-05-16 | 1966-05-31 | Philips Corp | Substituted tertiary amino compounds having valuable pharmacological properties |
| GB1177407A (en) * | 1967-05-12 | 1970-01-14 | Science Union & Cie | New Benzoic Acid Esters |
| DE1643262C3 (de) * | 1967-12-13 | 1975-06-26 | C.H. Boehringer Sohn, 6507 Ingelheim | i-Phenoxy^-hydroxy-S-alklyaminopropane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| DE1922003C3 (de) * | 1969-04-30 | 1979-10-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | N-(3-Aryloxy-2-hydroxypropyl)-aminocarbonsäuren, deren Ester, Amide und Salze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung von Herzinsuffizienz |
| US4220659A (en) * | 1974-02-22 | 1980-09-02 | Boehringer Ingelheim Gmbh | 1-Phenoxy-2-hydroxy-3-alkynylamino-propanes and salts thereof |
| US4313889A (en) * | 1975-09-22 | 1982-02-02 | Merck & Co., Inc. | Soft quaternary surface active agents |
| IT1116037B (it) * | 1979-04-23 | 1986-02-10 | Sigma Tau Ind Farmaceuti | Esteri e ammidi di acil carnitine loro procedimenti di preparazione e loro uso terapeutico |
| US4405642A (en) * | 1980-11-28 | 1983-09-20 | American Hospital Supply Corporation | Method for treatment or prophylaxis of cardiac disorders |
-
1980
- 1980-11-28 US US06/211,341 patent/US4405642A/en not_active Expired - Lifetime
-
1981
- 1981-10-29 EP EP81305130A patent/EP0053436B1/en not_active Expired
- 1981-11-04 NZ NZ198871A patent/NZ198871A/en unknown
- 1981-11-13 ZA ZA817891A patent/ZA817891B/xx unknown
- 1981-11-16 JP JP57500009A patent/JPS57502125A/ja active Pending
- 1981-11-16 EP EP81903190A patent/EP0065964B1/en not_active Expired
- 1981-11-16 WO PCT/US1981/001517 patent/WO1982001868A1/en active IP Right Grant
- 1981-11-16 AU AU78967/81A patent/AU547994B2/en not_active Ceased
- 1981-11-16 PH PH26498A patent/PH18954A/en unknown
- 1981-11-24 IL IL64344A patent/IL64344A/xx not_active IP Right Cessation
- 1981-11-26 CA CA000390967A patent/CA1180344A/en not_active Expired
- 1981-11-26 GR GR66623A patent/GR76922B/el unknown
- 1981-11-28 KR KR1019810004659A patent/KR880001828B1/ko active
-
1982
- 1982-07-28 DK DK336682A patent/DK163989C/da active
Also Published As
| Publication number | Publication date |
|---|---|
| EP0065964B1 (en) | 1985-10-23 |
| EP0053436A1 (en) | 1982-06-09 |
| GR76922B (da) | 1984-09-04 |
| EP0065964A1 (en) | 1982-12-08 |
| PH18954A (en) | 1985-11-26 |
| IL64344A (en) | 1985-11-29 |
| AU547994B2 (en) | 1985-11-14 |
| ZA817891B (en) | 1983-03-30 |
| CA1180344A (en) | 1985-01-02 |
| WO1982001868A1 (en) | 1982-06-10 |
| EP0065964A4 (en) | 1983-04-06 |
| EP0053436B1 (en) | 1986-03-12 |
| DK336682A (da) | 1982-07-28 |
| JPS57502125A (da) | 1982-12-02 |
| KR830007512A (ko) | 1983-10-21 |
| DK163989B (da) | 1992-04-27 |
| US4405642A (en) | 1983-09-20 |
| KR880001828B1 (ko) | 1988-09-20 |
| NZ198871A (en) | 1985-07-31 |
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