DE3382764T2 - Humane-humane hybridomas für neoplasmen. - Google Patents

Humane-humane hybridomas für neoplasmen.

Info

Publication number
DE3382764T2
DE3382764T2 DE3382764T DE3382764T DE3382764T2 DE 3382764 T2 DE3382764 T2 DE 3382764T2 DE 3382764 T DE3382764 T DE 3382764T DE 3382764 T DE3382764 T DE 3382764T DE 3382764 T2 DE3382764 T2 DE 3382764T2
Authority
DE
Germany
Prior art keywords
humane
hybridomas
monoclonal antibodies
neoplasms
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3382764T
Other languages
English (en)
Other versions
DE3382764D1 (de
Inventor
Harold H Handley
Mark C Glassy
Hideaki Hagiwara
Yoshihide Hagiwara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California filed Critical University of California
Publication of DE3382764D1 publication Critical patent/DE3382764D1/de
Application granted granted Critical
Publication of DE3382764T2 publication Critical patent/DE3382764T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE3382764T 1982-05-21 1983-05-20 Humane-humane hybridomas für neoplasmen. Expired - Lifetime DE3382764T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP57084843A JPS58201994A (ja) 1982-05-21 1982-05-21 抗原特異的ヒト免疫グロブリンの生産方法
PCT/US1983/000781 WO1983004313A1 (en) 1982-05-21 1983-05-20 Human-human hybridomas for neoplasms

Publications (2)

Publication Number Publication Date
DE3382764D1 DE3382764D1 (de) 1994-12-22
DE3382764T2 true DE3382764T2 (de) 1995-03-16

Family

ID=13842073

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3382764T Expired - Lifetime DE3382764T2 (de) 1982-05-21 1983-05-20 Humane-humane hybridomas für neoplasmen.

Country Status (13)

Country Link
EP (1) EP0109441B1 (de)
JP (2) JPS58201994A (de)
AT (1) ATE114189T1 (de)
AU (1) AU560595B2 (de)
CZ (1) CZ280677B6 (de)
DE (1) DE3382764T2 (de)
DK (1) DK164510C (de)
FI (1) FI86077C (de)
HU (1) HU190908B (de)
IN (1) IN157982B (de)
SK (1) SK356683A3 (de)
WO (1) WO1983004313A1 (de)
ZA (1) ZA833686B (de)

Families Citing this family (113)

* Cited by examiner, † Cited by third party
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US4613576A (en) * 1983-03-09 1986-09-23 Sloan-Kettering Institute For Cancer Research Human monoclonal antibodies to cancer cells
US4693966A (en) * 1983-03-11 1987-09-15 Sloan-Kettering Institute For Cancer Research Human monoclonal antibodies from lymphocytes of patients with malignant melanoma
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WO1985002411A1 (en) * 1983-11-25 1985-06-06 The University Of Melbourne Cell line and monoclonal antibody
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CA1320689C (en) * 1984-03-30 1993-07-27 Alain Schreiber Monoclonal antibody specific for human basal cell surface antigen
US4886745A (en) * 1984-03-30 1989-12-12 Syntex Inc. Monoclonal antibody specific for human basal cell surface antigen
JPS6133125A (ja) * 1984-07-25 1986-02-17 Morinaga & Co Ltd ヒト単クロ−ン性抗肺ガン細胞抗体
US4761377A (en) * 1984-10-15 1988-08-02 The Regents Of The University Of California Human-human hybrid cell lines that produce antibodies against antigenic determinants on cancer cells
JPS61130300A (ja) * 1984-11-27 1986-06-18 ザ　ボ−ド　オブ　トラステイ−ズ　オブ　ザ　レランド　スタンフオ−ド　ジユニア　ユニバ−シテイ ヒトモノクロ−ナル抗体
US5106746A (en) * 1985-05-22 1992-04-21 E. I. Du Pont De Nemours And Company Process for the in vitro immunization of human splenocytes against tumor associated antigens
US5776093A (en) 1985-07-05 1998-07-07 Immunomedics, Inc. Method for imaging and treating organs and tissues
JPH0655680B2 (ja) * 1985-10-26 1994-07-27 萩原 義秀 悪性腫瘍用ヒトモノクロナル抗体複合剤
EP0222360A3 (de) * 1985-11-12 1989-03-15 Biotherapeutics Inc. Verfahren zur Herstellung von einem patientspezifischen zytotoxischen Reagenz und Zubereitung
JPH0767388B2 (ja) * 1986-01-13 1995-07-26 三菱化学株式会社 抗体産生細胞株の樹立方法
US5434076A (en) * 1989-12-18 1995-07-18 Board Of Regents, The University Of Texas System Tumor-specific, cell surface-binding monoclonal antibodies
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JPH04346792A (ja) * 1991-05-22 1992-12-02 Hagiwara Yoshihide 抗癌ヒトモノクローナル抗体のアミノ酸配列及びそれをコードするｄｎａ塩基配列
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NZ198851A (en) * 1980-11-07 1984-07-31 Wistar Inst Stable,continuous human myeloma cell line capable of hybridisation with antibody-producing cells:production of hybrid cell line

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DE3382764D1 (de) 1994-12-22
SK279249B6 (sk) 1998-08-05
DK164510B (da) 1992-07-06
WO1983004313A1 (en) 1983-12-08
EP0109441B1 (de) 1994-11-17
FI840219A0 (fi) 1984-01-19
SK356683A3 (en) 1998-08-05
AU1772983A (en) 1983-12-16
FI86077C (fi) 1992-07-10
JPS58201994A (ja) 1983-11-25
DK164510C (da) 1992-11-23
DK25084A (da) 1984-01-20
EP0109441A1 (de) 1984-05-30
JPS60501359A (ja) 1985-08-22
CZ356683A3 (en) 1995-11-15
EP0109441A4 (de) 1986-09-22
AU560595B2 (en) 1987-04-09
FI840219A (fi) 1984-01-19
IN157982B (de) 1986-08-09
HU190908B (en) 1986-12-28
DK25084D0 (da) 1984-01-20
JPH0159878B2 (de) 1989-12-20
FI86077B (fi) 1992-03-31
ATE114189T1 (de) 1994-12-15
CZ280677B6 (cs) 1996-04-17
ZA833686B (en) 1984-09-26

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