DE3586440T2 - Zur diagnose von menschlichem magen- oder brustkrebs zu verwendender monoklonaler antikoerper. - Google Patents

Zur diagnose von menschlichem magen- oder brustkrebs zu verwendender monoklonaler antikoerper.

Info

Publication number
DE3586440T2
DE3586440T2 DE8585303481T DE3586440T DE3586440T2 DE 3586440 T2 DE3586440 T2 DE 3586440T2 DE 8585303481 T DE8585303481 T DE 8585303481T DE 3586440 T DE3586440 T DE 3586440T DE 3586440 T2 DE3586440 T2 DE 3586440T2
Authority
DE
Germany
Prior art keywords
diagnosis
breast cancer
monoclonal antibodies
human stomach
cancer monoclonal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585303481T
Other languages
English (en)
Other versions
DE3586440D1 (de
Inventor
Setsuo Hirohashi
Yukio Shimosato
Masahiko Watanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Kayaku Co Ltd
Original Assignee
Nippon Kayaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP59097549A external-priority patent/JPS60243026A/ja
Priority claimed from JP59101769A external-priority patent/JPS60246324A/ja
Application filed by Nippon Kayaku Co Ltd filed Critical Nippon Kayaku Co Ltd
Application granted granted Critical
Publication of DE3586440D1 publication Critical patent/DE3586440D1/de
Publication of DE3586440T2 publication Critical patent/DE3586440T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046—Stomach, Intestines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3015—Breast
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/863—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving IgM
    • Y10S530/864—Monoclonal
DE8585303481T 1984-05-17 1985-05-17 Zur diagnose von menschlichem magen- oder brustkrebs zu verwendender monoklonaler antikoerper. Expired - Lifetime DE3586440T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59097549A JPS60243026A (ja) 1984-05-17 1984-05-17 モノクロ−ナル抗体
JP59101769A JPS60246324A (ja) 1984-05-22 1984-05-22 モノクロ−ナル抗体の製造法

Publications (2)

Publication Number Publication Date
DE3586440D1 DE3586440D1 (de) 1992-09-10
DE3586440T2 true DE3586440T2 (de) 1993-01-14

Family

ID=26438708

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585303481T Expired - Lifetime DE3586440T2 (de) 1984-05-17 1985-05-17 Zur diagnose von menschlichem magen- oder brustkrebs zu verwendender monoklonaler antikoerper.

Country Status (4)

Country Link
US (1) US4683200A (de)
EP (1) EP0161941B1 (de)
KR (1) KR930003912B1 (de)
DE (1) DE3586440T2 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294172B1 (en) 1983-08-12 2001-09-25 Dade Behring Marburg Gmbh Monoclonal antibodies with specificity for membrane-associated antigens
JPS6144900A (ja) * 1984-08-08 1986-03-04 Green Cross Corp:The モノクロ−ナル抗体及び癌抗原検出用試薬
EP0180413B1 (de) * 1984-10-26 1991-10-02 Wakunaga Seiyaku Kabushiki Kaisha Monoklonaler Antikörper gegen menschlichen Krebs
EP0218158A3 (de) * 1985-09-30 1988-12-07 Asahi Kasei Kogyo Kabushiki Kaisha Menschlicher monoklonaler Antikörper, B-Zell-Linie für die Herstellung dieses Antikörpers und Verfahren zur Herstellung dieser B-Zell-Linie und Antikörper.
US4990454A (en) * 1985-11-12 1991-02-05 Nihon Medi-Physics Co., Ltd. YH206 cell line and monoclonal antibody produced by it
US4916055A (en) * 1985-12-13 1990-04-10 Baylor College Of Medicine Detection of human cancer with a monoclonal antibody specific for antigen gp650
EP0232871A3 (de) * 1986-02-07 1989-03-15 Yoshitomi Pharmaceutical Industries, Ltd. Menschlicher monoklonaler Antikörper, Hybridoma zu seiner Herstellung und seine Verwendung
JPS62207298A (ja) * 1986-03-06 1987-09-11 Kyowa Hakko Kogyo Co Ltd 抗ヒト胃癌単クロ−ン性抗体
JPS6319561A (ja) * 1986-07-11 1988-01-27 Kyowa Hakko Kogyo Co Ltd 抗ヒト肺癌単クロ−ン性抗体
JPH0673470B2 (ja) * 1986-07-15 1994-09-21 協和醗酵工業株式会社 抗ヒト胃癌単クロ−ン性抗体ａｍｃ−４６２
JP2519038B2 (ja) * 1986-07-29 1996-07-31 郁男 山科 単クロ―ン抗体及びその製造方法
EP0259773A3 (de) * 1986-09-10 1990-05-30 Asahi Kasei Kogyo Kabushiki Kaisha Ein Antikörper spezifisch gegen ein Krebsantigen
US4863851A (en) * 1986-10-20 1989-09-05 The Upjohn Company Monoclonal antibody to prostate secretory protein
NZ222509A (en) * 1986-11-19 1993-03-26 Oncogen Hybridoma cell line producing antibodies binding to tumour-associated mucin antigen
US6004761A (en) * 1986-11-19 1999-12-21 Sanofi Method for detecting cancer using monoclonal antibodies to new mucin epitopes
JPS63159763A (ja) * 1986-12-24 1988-07-02 Fujirebio Inc 逆受身凝集反応試薬
US5212085A (en) * 1987-12-09 1993-05-18 The General Hospital Corporation Sf-25 colon adenocarcinoma antigen, and antibodies with recognize this antigen
CA1340110C (en) * 1987-12-09 1998-11-03 Jack R. Wands Carcinoma-associated antigens, and antibodies which recognize these antigens
AU632469B2 (en) * 1988-04-04 1993-01-07 Johns Hopkins University, The A method for early detection of lung cancer
US5242824A (en) * 1988-12-22 1993-09-07 Oncogen Monoclonal antibody to human carcinomas
DE3909799A1 (de) 1989-03-24 1990-09-27 Behringwerke Ag Monoklonale antikoerper (mak) gegen tumorassoziierte antigene, ihre herstellung und verwendung
US5100392A (en) * 1989-12-08 1992-03-31 Biosynthesis, Inc. Implantable device for administration of drugs or other liquid solutions
US5652373A (en) * 1990-01-15 1997-07-29 Yeda Research And Development Co. Ltd. Engraftment and development of xenogeneic cells in normal mammals having reconstituted hematopoetic deficient immune systems
US5849288A (en) * 1990-01-15 1998-12-15 Yeda Research And Development Co. Ltd. Method for production of monoclonal antibodies in chimeric mice or rats having xenogeneic antibody-producing cells
US5858328A (en) * 1991-06-04 1999-01-12 Yeda Research And Development Co. Ltd. Animal model for hepatitis virus infection
US5849987A (en) * 1992-06-02 1998-12-15 Yeda Research And Development Co. Ltd. Animal model for hepatitis virus infection
US5804160A (en) * 1991-06-04 1998-09-08 Yeda Research And Development Co. Ltd Animal model for hepatitis virus infection
US5866757A (en) * 1992-06-02 1999-02-02 Yeda Research And Development Co. Ltd. Engraftment and development of xenogeneic cells in normal mammals having reconstituted hematopoetic deficient immune systems
JPH07132083A (ja) * 1993-11-12 1995-05-23 Res Dev Corp Of Japan 毛包組織に対するモノクローナル抗体と、この抗体を 産生するハイブリドーマ、およびこのハイブリドーマ の作成法
KR100455310B1 (ko) * 1996-12-31 2005-01-13 에스케이케미칼주식회사 간암세포를갖는랫드모델및그제조방법
US7229621B2 (en) 1998-10-20 2007-06-12 Torrey Pines Institute For Molecular Studies Method to enhance the immunogenicity of an antigen
US6210672B1 (en) 1998-10-20 2001-04-03 Torrey Pines Institute For Molecular Studies Topical immunostimulation to induce Langerhans cell migration
US20030072812A1 (en) * 2001-05-10 2003-04-17 Sirbasku David A Breast cancer eradication program
US7863011B2 (en) * 2000-05-10 2011-01-04 Signe Biopharma, Inc. Screening method for predicting susceptibility to breast cancer
MXPA02011093A (es) 2000-05-10 2004-08-19 David A Sirbasku Composiciones y metodos para el diagnostico, tratamiento y prevencion de canceres que responden a la hormona esteroidea.
AU2002343714A1 (en) * 2001-11-13 2003-05-26 David A. Sirbasku Breast cancer eradication program
CA2474880C (en) * 2002-01-31 2009-11-24 Japan Science And Technology Agency Production of hybridoma producing antihuman cenp-a peptide monoclonal antibody and method of using the same
EP2185718B1 (de) 2007-08-03 2017-10-04 MUSC Foundation For Research Development Menschliche monoklonale antikörper und verfahren zu ihrer herstellung
CN108753733B (zh) * 2018-04-11 2022-03-25 南京泰斯德生物科技有限公司 杂交瘤细胞株及其产生的抗糖基单克隆抗体以及制备方法与制剂

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172124A (en) * 1978-04-28 1979-10-23 The Wistar Institute Method of producing tumor antibodies
US4349528A (en) * 1979-11-21 1982-09-14 The Wistar Institute Monocolonal hybridoma antibody specific for high molecular weight carcinoembryonic antigen
US4584268A (en) * 1981-10-13 1986-04-22 Ceriani Roberto Luis Method and compositions for carcinoma diagnosis
US4579827A (en) * 1983-03-11 1986-04-01 Sloan-Kettering Institute For Cancer Research Monoclonal antibodies to human gastrointestinal cancers and hybridoma method of production of the monoclonal antibodies

Also Published As

Publication number Publication date
KR850007979A (ko) 1985-12-11
EP0161941B1 (de) 1992-08-05
EP0161941A3 (en) 1987-08-05
DE3586440D1 (de) 1992-09-10
EP0161941A2 (de) 1985-11-21
US4683200A (en) 1987-07-28
KR930003912B1 (ko) 1993-05-15

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