MXPA02011093A - Composiciones y metodos para el diagnostico, tratamiento y prevencion de canceres que responden a la hormona esteroidea. - Google Patents
Composiciones y metodos para el diagnostico, tratamiento y prevencion de canceres que responden a la hormona esteroidea.Info
- Publication number
- MXPA02011093A MXPA02011093A MXPA02011093A MXPA02011093A MXPA02011093A MX PA02011093 A MXPA02011093 A MX PA02011093A MX PA02011093 A MXPA02011093 A MX PA02011093A MX PA02011093 A MXPA02011093 A MX PA02011093A MX PA02011093 A MXPA02011093 A MX PA02011093A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- methods
- steroid hormone
- hormone responsive
- diagnosis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
- C12N5/0629—Keratinocytes; Whole skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
- C12N5/0631—Mammary cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
- C12N2500/14—Calcium; Ca chelators; Calcitonin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
- C12N2501/392—Sexual steroids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/395—Thyroid hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/02—Drug screening
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Developmental Biology & Embryology (AREA)
- High Energy & Nuclear Physics (AREA)
- Virology (AREA)
Abstract
Las composiciones y metodos que usan el sistema inmune secretor natural del cuerpo en una nueva forma en contra de tumores que responden a la hormona esteroidea de los senos y la prostata, asi como otros tejidos glandulares/mucosa epitelial como el colon, ovarios, endometrio, rinon, vejiga, estomago, pancreas y glandula secretora de pituitaria son provistos. Tambien provistos estan nuevos modos de identificar bacterias carcinogenas en un tejido o fluido del cuerpo para proveer mejores terapias contra el cancer y medidas preventivas que han estado disponibles anteriormente.
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20331400P | 2000-05-10 | 2000-05-10 | |
US20834800P | 2000-05-31 | 2000-05-31 | |
US20811100P | 2000-05-31 | 2000-05-31 | |
US22907100P | 2000-08-30 | 2000-08-30 | |
US23127300P | 2000-09-08 | 2000-09-08 | |
PCT/US2001/015171 WO2001086307A2 (en) | 2000-05-10 | 2001-05-10 | Compositions and methods for the diagnosis, treatment and prevention of steroid hormone responsive cancers |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA02011093A true MXPA02011093A (es) | 2004-08-19 |
Family
ID=27539481
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA02011092A MXPA02011092A (es) | 2000-05-10 | 2001-05-10 | Composiciones y metodos para demostrar la regulacion del sistema inmune secretor del crecimiento de la celula de cancer que responde a la hormona esteroidea. |
MXPA02011093A MXPA02011093A (es) | 2000-05-10 | 2001-05-10 | Composiciones y metodos para el diagnostico, tratamiento y prevencion de canceres que responden a la hormona esteroidea. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA02011092A MXPA02011092A (es) | 2000-05-10 | 2001-05-10 | Composiciones y metodos para demostrar la regulacion del sistema inmune secretor del crecimiento de la celula de cancer que responde a la hormona esteroidea. |
Country Status (8)
Country | Link |
---|---|
US (4) | US7947463B2 (es) |
EP (5) | EP2394660A1 (es) |
AT (2) | ATE485520T1 (es) |
AU (2) | AU2001272908A1 (es) |
CA (2) | CA2409765A1 (es) |
DE (1) | DE60143320D1 (es) |
MX (2) | MXPA02011092A (es) |
WO (2) | WO2001086307A2 (es) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7863011B2 (en) * | 2000-05-10 | 2011-01-04 | Signe Biopharma, Inc. | Screening method for predicting susceptibility to breast cancer |
US8119138B2 (en) * | 2000-05-10 | 2012-02-21 | Signe Biopharma Inc. | Anti-estrogen and immune modulator combinations for treating breast cancer |
MXPA02011092A (es) | 2000-05-10 | 2004-08-19 | David A Sirbasku | Composiciones y metodos para demostrar la regulacion del sistema inmune secretor del crecimiento de la celula de cancer que responde a la hormona esteroidea. |
US20030072812A1 (en) * | 2001-05-10 | 2003-04-17 | Sirbasku David A | Breast cancer eradication program |
WO2003001891A2 (en) * | 2001-06-28 | 2003-01-09 | Entelos, Inc. | Method and apparatus for computer modeling of an adaptive immune response |
EP2299265A1 (en) | 2001-11-13 | 2011-03-23 | Signe BioPharma Inc. | Cancer eradication program |
AU2002343704A1 (en) * | 2001-11-14 | 2003-05-26 | David A. Sirbasku | Screening method for predicting susceptibility to breast cancer |
WO2003041654A2 (en) * | 2001-11-14 | 2003-05-22 | Sirbasku David A | Anti-estrogen and immune modulator combinations for treating breast cancer |
US7364846B2 (en) * | 2002-10-11 | 2008-04-29 | Molecular Devices Corporation | Gene expression profiling from FFPE samples |
EP2065466B1 (en) * | 2004-05-28 | 2014-07-09 | Asuragen, Inc. | Methods and compositions involving MicroRNA |
EP2281889B1 (en) | 2004-11-12 | 2014-07-30 | Asuragen, Inc. | Methods and compositions involving miRNA and miRNA inhibitor molecules |
ATE552334T1 (de) * | 2005-09-13 | 2012-04-15 | Takara Bio Inc | Serumfreies medium zur herstellung von retroviralen vektoren |
AU2007299828C1 (en) * | 2006-09-19 | 2014-07-17 | Interpace Diagnostics, Llc | MicroRNAs differentially expressed in pancreatic diseases and uses thereof |
JP2010510964A (ja) * | 2006-09-19 | 2010-04-08 | アシュラジェン インコーポレイテッド | 治療的介入の標的としての、miR−15、miR−26、miR−31、miR−145、miR−147、miR−188、miR−215、miR−216、miR−331、mmu−miR−292−3pによって調節される遺伝子および経路 |
CA2671294A1 (en) * | 2006-12-08 | 2008-06-19 | Asuragen, Inc. | Mir-21 regulated genes and pathways as targets for therapeutic intervention |
CN101622349A (zh) * | 2006-12-08 | 2010-01-06 | 奥斯瑞根公司 | 作为治疗性干预靶标的miR-21调节的基因和途径 |
CN101675165A (zh) * | 2006-12-08 | 2010-03-17 | 奥斯瑞根公司 | Let-7微小rna的功能和靶标 |
US8709413B2 (en) * | 2006-12-13 | 2014-04-29 | Michael R. Simon | Treatment of celiac disease with IgA |
US20090175827A1 (en) * | 2006-12-29 | 2009-07-09 | Byrom Mike W | miR-16 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION |
US20090131354A1 (en) * | 2007-05-22 | 2009-05-21 | Bader Andreas G | miR-126 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION |
US20090232893A1 (en) * | 2007-05-22 | 2009-09-17 | Bader Andreas G | miR-143 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION |
US8015145B2 (en) * | 2007-06-05 | 2011-09-06 | Siemens Medical Solutions Usa, Inc. | System for providing healthcare operation specific user interface display images |
CA2689974A1 (en) * | 2007-06-08 | 2008-12-18 | Asuragen, Inc. | Mir-34 regulated genes and pathways as targets for therapeutic intervention |
US8361714B2 (en) | 2007-09-14 | 2013-01-29 | Asuragen, Inc. | Micrornas differentially expressed in cervical cancer and uses thereof |
US20090186015A1 (en) * | 2007-10-18 | 2009-07-23 | Latham Gary J | Micrornas differentially expressed in lung diseases and uses thereof |
US8071562B2 (en) * | 2007-12-01 | 2011-12-06 | Mirna Therapeutics, Inc. | MiR-124 regulated genes and pathways as targets for therapeutic intervention |
US20090192114A1 (en) * | 2007-12-21 | 2009-07-30 | Dmitriy Ovcharenko | miR-10 Regulated Genes and Pathways as Targets for Therapeutic Intervention |
US20090193338A1 (en) | 2008-01-28 | 2009-07-30 | Trevor Fiatal | Reducing network and battery consumption during content delivery and playback |
US20090263803A1 (en) * | 2008-02-08 | 2009-10-22 | Sylvie Beaudenon | Mirnas differentially expressed in lymph nodes from cancer patients |
EP2268832A2 (en) * | 2008-03-06 | 2011-01-05 | Asuragen, INC. | Microrna markers for recurrence of colorectal cancer |
EP2271757A2 (en) * | 2008-03-26 | 2011-01-12 | Asuragen, INC. | Compositions and methods related to mir-16 and therapy of prostate cancer |
EP2990487A1 (en) | 2008-05-08 | 2016-03-02 | Asuragen, INC. | Compositions and methods related to mirna modulation of neovascularization or angiogenesis |
US20100179213A1 (en) * | 2008-11-11 | 2010-07-15 | Mirna Therapeutics, Inc. | Methods and Compositions Involving miRNAs In Cancer Stem Cells |
EP2442641A4 (en) * | 2009-06-16 | 2016-03-09 | Univ Columbia | METHOD FOR REDUCING SIDE EFFECTS OF THE TRANSFUSION OF AGED RED BLOOD CELLS |
US8993347B2 (en) | 2009-12-17 | 2015-03-31 | Cornell University | Methods for detecting antibodies in mucosal samples and device for sampling mucosal material |
WO2013040251A2 (en) | 2011-09-13 | 2013-03-21 | Asurgen, Inc. | Methods and compositions involving mir-135b for distinguishing pancreatic cancer from benign pancreatic disease |
EP3049514B1 (en) * | 2013-09-24 | 2019-11-20 | University Of Miami | Cell culture media |
PT3126383T (pt) | 2014-04-03 | 2019-03-22 | Igm Biosciences Inc | Cadeia j modificada |
WO2016141303A2 (en) | 2015-03-04 | 2016-09-09 | Igm Biosciences, Inc. | Cd20 binding molecules and uses thereof |
CN108463472A (zh) * | 2015-09-30 | 2018-08-28 | Igm生物科学有限公司 | 具有修饰的j-链的结合分子 |
CA2999284C (en) | 2015-09-30 | 2023-06-13 | Igm Biosciences A/S | Binding molecules with modified j-chain |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4393071A (en) | 1975-03-17 | 1983-07-12 | Naoharu Fujii | Method of treating gastric, mammary, lung and uterus tumors |
FR2558373B1 (fr) | 1984-01-20 | 1987-07-03 | Mauvais Jarvis Pierre | Medicament antioestrogene a base de 4-hydroxytamoxifene pour administration percutanee |
US4683200A (en) | 1984-05-17 | 1987-07-28 | Setsuo Hirohashi | Monoclonal antibody to human cancer antigen and method for producing same |
GB8607137D0 (en) | 1986-03-21 | 1986-04-30 | Efamol Ltd | Compositions |
US4859585A (en) | 1986-04-17 | 1989-08-22 | Trustees Of Tufts College | In-vitro methods for identifying compositions which are agonists and antagonists of estrogens |
US5135849A (en) * | 1986-04-17 | 1992-08-04 | Trustees Of Tufts College | In-vitro methods for identifying compositions which are agonists and antagonists of androgens |
GB8628104D0 (en) | 1986-11-25 | 1986-12-31 | Connaught Lab | Pasteurization of immunoglobin solutions |
US5980896A (en) | 1989-06-30 | 1999-11-09 | Bristol-Myers Squibb Company | Antibodies reactive with human carcinomas |
DE3927112C1 (es) * | 1989-08-17 | 1990-10-25 | Biotest Pharma Gmbh, 6072 Dreieich, De | |
CN1057785A (zh) | 1990-04-16 | 1992-01-15 | 哈佛大学校长及研究员协会 | 合成多聚免疫球蛋白受体,受体-抗体复合物,生产及应用 |
RU1837891C (ru) | 1991-01-31 | 1993-08-30 | Keshelava Viktor V | Способ получени противоопухолевого средства |
WO1992013500A1 (en) | 1991-02-08 | 1992-08-20 | Surgical Innovations, Inc. | Method and apparatus for repair of inguinal hernias |
US6200547B1 (en) | 1994-01-26 | 2001-03-13 | Ferx Incorporated | Magnetically responsive compositions for carrying biologically active substances and methods of production and use |
US5405772A (en) * | 1993-06-18 | 1995-04-11 | Amgen Inc. | Medium for long-term proliferation and development of cells |
US5641863A (en) * | 1993-09-30 | 1997-06-24 | University Of Pennsylvania | Chimeric IgG Fc receptors |
GB9320820D0 (en) * | 1993-10-08 | 1993-12-01 | Biokine Tech Ltd | Compounds for medicinal use |
JPH07238036A (ja) | 1994-02-28 | 1995-09-12 | Green Cross Corp:The | 静注用グロブリン液状組成物のグロブリン二量体増加抑制方法 |
US5772995A (en) | 1994-07-18 | 1998-06-30 | Sidney Kimmel Cancer Center | Compositions and methods for enhanced tumor cell immunity in vivo |
US5866323A (en) * | 1995-04-07 | 1999-02-02 | Case Western Reserve University | Cancer diagnosis prognosis and therapy based on mutation of receptors for transforming growth factor β and homologous growth controlling factors |
US6902743B1 (en) | 1995-05-22 | 2005-06-07 | The United States Of America As Represented By The Secretary Of The Army | Therapeutic treatment and prevention of infections with a bioactive material(s) encapuslated within a biodegradable-bio-compatable polymeric matrix |
CA2224115A1 (en) | 1995-06-07 | 1996-12-19 | Washington University | Multidentate metal complexes and methods of making and using thereof |
WO1997046715A1 (en) * | 1996-06-03 | 1997-12-11 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Fc receptor polymorphism |
CA2261292C (en) * | 1996-07-25 | 2008-09-30 | Genzyme Corporation | Chondrocyte media formulations and culture procedures |
AU4330597A (en) * | 1996-08-30 | 1998-03-19 | Life Technologies, Inc. | Serum-free mammalian cell culture medium, and uses thereof |
CA2297907A1 (en) * | 1997-07-28 | 1999-02-04 | Yale University | Human estrogen receptor beta |
US6020161A (en) | 1997-08-19 | 2000-02-01 | Smithkline Beecham Corporation | PIGR-1, a member of immunoglobulin gene superfamily |
CA2316397A1 (en) | 1997-12-24 | 1999-07-08 | Corixa Corporation | Compounds for immunotherapy and diagnosis of breast cancer and methods for their use |
WO2000005403A1 (en) * | 1998-07-24 | 2000-02-03 | Uab Research Foundation | GENETIC POLYMORPHISM IN THE RECEPTOR FOR IgA |
IL125608A0 (en) * | 1998-07-30 | 1999-03-12 | Yeda Res & Dev | Tumor associated antigen peptides and use of same as anti-tumor vaccines |
JP2002529065A (ja) | 1998-11-06 | 2002-09-10 | ミリアド・ジェネティックス・インコーポレイテッド | 染色体17q連鎖−前立腺癌感受性遺伝子 |
EP1235847B1 (en) | 1999-11-29 | 2016-01-20 | The Trustees of Columbia University in the City of New York | ISOLATION OF FIVE NOVEL GENES CODING FOR NEW Fc RECEPTORS-TYPE MELANOMA INVOLVED IN THE PATHOGENESIS OF LYMPHOMA/MELANOMA |
CA2400874A1 (en) | 2000-02-25 | 2001-08-30 | The Regents Of The University Of California | Membrane estrogen receptor-directed therapy in breast cancer |
US6763307B2 (en) | 2000-03-06 | 2004-07-13 | Bioseek, Inc. | Patient classification |
MXPA02009449A (es) | 2000-03-27 | 2003-09-22 | Univ California | Ligandos dirigidos a la region no del eje del componente no secretor de la pigr y metodos de uso de los mismos. |
MXPA02011092A (es) | 2000-05-10 | 2004-08-19 | David A Sirbasku | Composiciones y metodos para demostrar la regulacion del sistema inmune secretor del crecimiento de la celula de cancer que responde a la hormona esteroidea. |
US8119138B2 (en) | 2000-05-10 | 2012-02-21 | Signe Biopharma Inc. | Anti-estrogen and immune modulator combinations for treating breast cancer |
EP2299265A1 (en) | 2001-11-13 | 2011-03-23 | Signe BioPharma Inc. | Cancer eradication program |
AU2002343704A1 (en) | 2001-11-14 | 2003-05-26 | David A. Sirbasku | Screening method for predicting susceptibility to breast cancer |
-
2001
- 2001-05-10 MX MXPA02011092A patent/MXPA02011092A/es active IP Right Grant
- 2001-05-10 AU AU2001272908A patent/AU2001272908A1/en not_active Abandoned
- 2001-05-10 CA CA002409765A patent/CA2409765A1/en not_active Abandoned
- 2001-05-10 WO PCT/US2001/015171 patent/WO2001086307A2/en active Application Filing
- 2001-05-10 EP EP10185003A patent/EP2394660A1/en not_active Ceased
- 2001-05-10 MX MXPA02011093A patent/MXPA02011093A/es active IP Right Grant
- 2001-05-10 EP EP01952116A patent/EP1366366B1/en not_active Expired - Lifetime
- 2001-05-10 DE DE60143320T patent/DE60143320D1/de not_active Expired - Lifetime
- 2001-05-10 AT AT01952116T patent/ATE485520T1/de not_active IP Right Cessation
- 2001-05-10 WO PCT/US2001/015183 patent/WO2001085210A2/en active Application Filing
- 2001-05-10 US US09/852,547 patent/US7947463B2/en not_active Expired - Fee Related
- 2001-05-10 US US09/852,958 patent/US7947275B2/en not_active Expired - Fee Related
- 2001-05-10 EP EP01948216A patent/EP1328293B1/en not_active Expired - Lifetime
- 2001-05-10 AU AU2001269690A patent/AU2001269690A1/en not_active Abandoned
- 2001-05-10 EP EP10184776A patent/EP2359857A3/en not_active Withdrawn
- 2001-05-10 AT AT01948216T patent/ATE545433T1/de active
- 2001-05-10 CA CA002409150A patent/CA2409150A1/en not_active Abandoned
- 2001-05-10 EP EP10184646.7A patent/EP2394659B1/en not_active Expired - Lifetime
-
2011
- 2011-05-20 US US13/112,444 patent/US8563249B2/en not_active Expired - Fee Related
- 2011-05-20 US US13/112,391 patent/US20120115161A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2001086307A3 (en) | 2003-10-02 |
EP1366366A2 (en) | 2003-12-03 |
EP2394659B1 (en) | 2014-01-22 |
EP2359857A3 (en) | 2012-02-22 |
EP2359857A2 (en) | 2011-08-24 |
EP1366366B1 (en) | 2010-10-20 |
US7947275B2 (en) | 2011-05-24 |
MXPA02011092A (es) | 2004-08-19 |
US20020006630A1 (en) | 2002-01-17 |
ATE485520T1 (de) | 2010-11-15 |
EP2394659A1 (en) | 2011-12-14 |
WO2001086307A2 (en) | 2001-11-15 |
AU2001269690A1 (en) | 2001-11-20 |
DE60143320D1 (de) | 2010-12-02 |
US8563249B2 (en) | 2013-10-22 |
US20120028258A1 (en) | 2012-02-02 |
WO2001085210A3 (en) | 2003-04-17 |
WO2001085210A2 (en) | 2001-11-15 |
ATE545433T1 (de) | 2012-03-15 |
CA2409765A1 (en) | 2001-11-15 |
CA2409150A1 (en) | 2001-11-15 |
EP1328293A2 (en) | 2003-07-23 |
AU2001272908A1 (en) | 2001-11-20 |
US7947463B2 (en) | 2011-05-24 |
US20020012954A1 (en) | 2002-01-31 |
EP1328293B1 (en) | 2012-02-15 |
EP2394660A1 (en) | 2011-12-14 |
US20120115161A1 (en) | 2012-05-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MXPA02011093A (es) | Composiciones y metodos para el diagnostico, tratamiento y prevencion de canceres que responden a la hormona esteroidea. | |
SI1556058T1 (sl) | Farmacevtski sestavki, ki obsegajo estetrolne derivate, za uporabo pri zdravljenju raka | |
MXPA03001634A (es) | Polipeptido tumoral cripto. | |
WO2004050026A3 (en) | Compositions and methods for treating prostate cancer | |
EP1522594A3 (en) | Methods and kits for investigating cancer | |
WO2007015947A3 (en) | Methods and kits for the prediction of therapeutic success, recurrence free and overall survival in cancer therapies | |
WO2001008636A8 (en) | Polypeptides and polynucleotides for enhancing immune reactivity to her-2 protein | |
NZ524036A (en) | Treatment and diagnosis of cancer | |
NZ285159A (en) | Treatment of benign prostatic hyperplasia, endometriosis, prostatic carcinoma and obesity by administration of droloxifene | |
EP1365034A3 (en) | Methods and compositions for the prediction, diagnosis, prognosis, prevention and treatment of malignant neoplasia | |
EP1272636B8 (en) | A gene differentially expressed in breast and bladder cancer and encoded polypeptides | |
EA200970607A1 (ru) | Универсальная вакцина из опухолевых клеток для противораковой терапии и профилактического использования | |
HK1068261A1 (en) | Combinations comprisinga selective cyclooxygenase-2 inhibitor | |
BR0311146A (pt) | Uso de tibolona e de modulador de receptor de estrogênio seletivo, e, método e kit para o tratamento de um sintoma relacionado com a deficiência de estrogênio em um paciente do sexo feminino | |
MXPA02011563A (es) | Composicionesy metodos para la terapia y diagnostico de cancer de seno. | |
BR0214798A (pt) | Uso de anastrozol ou um sal farmaceuticamente aceitável do mesmo, e, métodos para reduzir a taxa de recorrência de câncer e a taxa de um novo tumor primário contralateral em uma mulher pós-menopausa tendo câncer de mama em estado inicial | |
Choudhury et al. | Metastatic prostatic carcinoma to breast or primary breast carcinoma? | |
DE60130541D1 (de) | Gewebe-spezifische protein 103p2d6, hochexprimiert in verschiedene krebsarten | |
Cante et al. | Penile metastasis from prostate cancer: a case report | |
Banerjee et al. | Penile metastasis: an unusual presentation of metastatic colonic cancer. | |
EP1147208A4 (en) | COMPOSITIONS AND METHODS FOR INTRADUCTAL GENE THERAPY | |
HK1048494A1 (en) | G protein-coupled receptor up-regulated in prostate cancer and uses thereof | |
Skoll et al. | Acral dermatofibrosarcoma protuberans with metastases | |
Bailey et al. | Cutaneous metastases of prostate cancer | |
Nyberg et al. | 445 Vulvar verrucous carcinoma: 15 years experience in a single norwegian academic cancer center |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
GB | Transfer or rights | ||
FG | Grant or registration |