ATE56046T1 - Monoklonale antikoerper gegen humane brustkarzinomzellen und ihre verwendung in der diagnose und therapie. - Google Patents
Monoklonale antikoerper gegen humane brustkarzinomzellen und ihre verwendung in der diagnose und therapie.Info
- Publication number
- ATE56046T1 ATE56046T1 AT84400420T AT84400420T ATE56046T1 AT E56046 T1 ATE56046 T1 AT E56046T1 AT 84400420 T AT84400420 T AT 84400420T AT 84400420 T AT84400420 T AT 84400420T AT E56046 T1 ATE56046 T1 AT E56046T1
- Authority
- AT
- Austria
- Prior art keywords
- monoclonal antibodies
- human breast
- breast carcinoma
- diagnosis
- therapy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3015—Breast
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
- A61K51/1051—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from breast, e.g. the antibody being herceptin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47222283A | 1983-03-04 | 1983-03-04 | |
EP84400420A EP0118365B1 (de) | 1983-03-04 | 1984-03-02 | Monoklonale Antikörper gegen humane Brustkarzinomzellen und ihre Verwendung in der Diagnose und Therapie |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE56046T1 true ATE56046T1 (de) | 1990-09-15 |
Family
ID=23874639
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT84400420T ATE56046T1 (de) | 1983-03-04 | 1984-03-02 | Monoklonale antikoerper gegen humane brustkarzinomzellen und ihre verwendung in der diagnose und therapie. |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0118365B1 (de) |
AT (1) | ATE56046T1 (de) |
CA (1) | CA1215331A (de) |
DE (1) | DE3483054D1 (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6294172B1 (en) | 1983-08-12 | 2001-09-25 | Dade Behring Marburg Gmbh | Monoclonal antibodies with specificity for membrane-associated antigens |
WO1985002411A1 (en) * | 1983-11-25 | 1985-06-06 | The University Of Melbourne | Cell line and monoclonal antibody |
JP2723203B2 (ja) * | 1984-01-06 | 1998-03-09 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | サイトケラチン腫瘍マーカー及びそれらの検出のためのアッセイ |
US5169774A (en) * | 1984-02-08 | 1992-12-08 | Cetus Oncology Corporation | Monoclonal anti-human breast cancer antibodies |
US4753894A (en) * | 1984-02-08 | 1988-06-28 | Cetus Corporation | Monoclonal anti-human breast cancer antibodies |
SE468231B (sv) * | 1984-05-18 | 1992-11-23 | Kabi Pharmacia Ab | Foerfarande foer att paavisa smaacelligt lungcarcinomantigen och anvaendning av antikroppar mot fukosylsialosylgangliotetraos foer framstaellning av komposition foer behandling eller in vivo/ diagnos |
SE455445B (sv) * | 1984-08-28 | 1988-07-11 | Pharmacia Ab | Antikroppar mot sialosyllaktotetraos (iv?723neuaclcose?714) och antikroppens resp antigenets anvendning vid tumordiagnostik |
US5032521A (en) * | 1984-12-05 | 1991-07-16 | The Salk Institute For Biological Studies | Monoclonal antibody specific for a mammary tumor cell surface antigen |
US4628032A (en) * | 1984-12-05 | 1986-12-09 | The Salk Institute For Biological Studies | Monoclonal antibody specific for a mammary tumor cytoplasmic antigen |
EP0184369B1 (de) * | 1984-12-05 | 1992-04-01 | The Salk Institute For Biological Studies | Monoklonaler Antikörper, spezifisch für Brustkrebszelloberflächenantigen |
US4938948A (en) * | 1985-10-07 | 1990-07-03 | Cetus Corporation | Method for imaging breast tumors using labeled monoclonal anti-human breast cancer antibodies |
JPS6296500A (ja) * | 1985-10-07 | 1987-05-02 | シータス オンコロジー コーポレイション | 抗−ヒト乳癌モノクロ−ナル抗体 |
AU601379B2 (en) * | 1985-11-07 | 1990-09-13 | Trustees Of Columbia University In The City Of New York, The | Antigen indicative of human breast cancer and assays based thereon |
US6004761A (en) * | 1986-11-19 | 1999-12-21 | Sanofi | Method for detecting cancer using monoclonal antibodies to new mucin epitopes |
DK554886A (da) * | 1986-11-19 | 1988-07-18 | Novo Industri As | Antistoffer |
AU613590B2 (en) * | 1986-11-19 | 1991-08-08 | Bristol-Myers Squibb Company | Hybridomas producing monoclonal antibodies to new mucin epitopes |
US5013645A (en) * | 1987-04-14 | 1991-05-07 | Abbott Laboratories | Immunological methods and materials for detection of tumor associated antigens |
US5635596A (en) * | 1987-10-30 | 1997-06-03 | Aderegem | Peptides derived from the pS2 protein |
FR2622700B1 (fr) * | 1987-10-30 | 1993-08-13 | Aderegem | Proteine et ses fragments representant l'expression specifique du gene ps2 des cancers du sein, anticorps obtenus a partir de ladite proteine et/ou de ses fragments, leurs applications a la detection et au diagnostic de cancers du sein |
WO1989006692A1 (en) * | 1988-01-12 | 1989-07-27 | Genentech, Inc. | Method of treating tumor cells by inhibiting growth factor receptor function |
US5720937A (en) * | 1988-01-12 | 1998-02-24 | Genentech, Inc. | In vivo tumor detection assay |
US5081032A (en) * | 1988-06-30 | 1992-01-14 | Kyowa Hakko Kogyo Co., Ltd. | Anti-human pulmonary adenocarcinoma monoclonal antibody |
DE3909799A1 (de) | 1989-03-24 | 1990-09-27 | Behringwerke Ag | Monoklonale antikoerper (mak) gegen tumorassoziierte antigene, ihre herstellung und verwendung |
IL94872A (en) * | 1989-06-30 | 1995-03-30 | Oncogen | Monoclonal or chimeric antibodies that react with human carcinoma, recombinant proteins that contain their anti-binding site, pharmaceutical preparations and kits that contain the |
US5281710A (en) * | 1990-08-01 | 1994-01-25 | The Scripps Research Institute | Dynemicin analogs: synthesis, methods of preparation and use |
US5242813A (en) * | 1990-10-12 | 1993-09-07 | The United States Of America As Represented By The Department Of Health And Human Services | Mouse monoclonal antibodies specific for normal primate tissue, malignant human cultural cell lines human tumors |
US5763415A (en) | 1995-08-03 | 1998-06-09 | John Hopkins University School Of Medicine | Destruction of the epithelium of an exocrine gland in the prophylactic and therapeutic treatment of cancer |
WO1997005898A1 (en) * | 1995-08-03 | 1997-02-20 | The Johns Hopkins University School Of Medicine | Delivery of an agent to the ductal epithelium in the prophylactic and therapeutic treatment of cancer |
CA2346048A1 (en) * | 1998-10-02 | 2000-04-13 | Windy Hill Technology, Inc. | Methods for identification, diagnosis, and treatment of breast cancer |
ZA200305980B (en) | 2001-02-12 | 2007-01-31 | Res Dev Foundation | Modified proteins, designer toxins, and methods of making thereof |
US7101977B2 (en) | 2001-07-17 | 2006-09-05 | Research Development Foundation | Therapeutic agents comprising pro-apoptotic proteins |
CN115349490B (zh) * | 2022-07-14 | 2024-01-12 | 成都中医药大学 | 一种卵巢储备功能低下动物模型的建立方法 |
CN115975036B (zh) * | 2022-08-18 | 2023-06-09 | 北京诺赛国际医学研究院 | 包含干细胞的药物组合物及其治疗癌症的用途 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4172124A (en) * | 1978-04-28 | 1979-10-23 | The Wistar Institute | Method of producing tumor antibodies |
JPS58201994A (ja) * | 1982-05-21 | 1983-11-25 | Hideaki Hagiwara | 抗原特異的ヒト免疫グロブリンの生産方法 |
-
1984
- 1984-03-02 DE DE8484400420T patent/DE3483054D1/de not_active Expired - Fee Related
- 1984-03-02 EP EP84400420A patent/EP0118365B1/de not_active Expired - Lifetime
- 1984-03-02 AT AT84400420T patent/ATE56046T1/de not_active IP Right Cessation
- 1984-03-02 CA CA000448717A patent/CA1215331A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0118365A2 (de) | 1984-09-12 |
EP0118365A3 (en) | 1985-09-11 |
CA1215331A (en) | 1986-12-16 |
DE3483054D1 (de) | 1990-10-04 |
EP0118365B1 (de) | 1990-08-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |