CN1089232C - 将微水溶性药物转化为非晶态的方法 - Google Patents

将微水溶性药物转化为非晶态的方法 Download PDF

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Publication number
CN1089232C
CN1089232C CN96196203A CN96196203A CN1089232C CN 1089232 C CN1089232 C CN 1089232C CN 96196203 A CN96196203 A CN 96196203A CN 96196203 A CN96196203 A CN 96196203A CN 1089232 C CN1089232 C CN 1089232C
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salt
acid
amorphous
soluble
slightly water
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Expired - Fee Related
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CN96196203A
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Chinese (zh)
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CN1192677A (zh
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宫本操
织田寿久
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Nissan Chemical Corp
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Nissan Chemical Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • External Artificial Organs (AREA)
  • Materials For Medical Uses (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Treatment Of Sludge (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN96196203A 1995-08-11 1996-08-08 将微水溶性药物转化为非晶态的方法 Expired - Fee Related CN1089232C (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP205936/95 1995-08-11
JP20593695 1995-08-11
JP31040095 1995-11-29
JP310400/95 1995-11-29
JP31040195 1995-11-29
JP310401/95 1995-11-29

Publications (2)

Publication Number Publication Date
CN1192677A CN1192677A (zh) 1998-09-09
CN1089232C true CN1089232C (zh) 2002-08-21

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN96196203A Expired - Fee Related CN1089232C (zh) 1995-08-11 1996-08-08 将微水溶性药物转化为非晶态的方法

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US (1) US6462093B1 (enExample)
EP (2) EP1356807A3 (enExample)
KR (1) KR100498813B1 (enExample)
CN (1) CN1089232C (enExample)
AT (1) ATE255405T1 (enExample)
AU (1) AU702088B2 (enExample)
CA (1) CA2228907A1 (enExample)
CZ (1) CZ296072B6 (enExample)
DE (1) DE69630964T2 (enExample)
MX (1) MX9800717A (enExample)
NO (1) NO320486B1 (enExample)
NZ (1) NZ315089A (enExample)
TW (1) TW487582B (enExample)
WO (1) WO1997006781A1 (enExample)

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CN121044616B (zh) * 2025-11-05 2026-02-13 北京大学 一种氨基酸介导的非晶态稀土氧化物的合成方法

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US6462093B1 (en) 2002-10-08
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