DE69630964T2 - Verfahren, um schwerlösliche arzneistoffe in einen amorphen zustand zu bringen - Google Patents
Verfahren, um schwerlösliche arzneistoffe in einen amorphen zustand zu bringen Download PDFInfo
- Publication number
- DE69630964T2 DE69630964T2 DE69630964T DE69630964T DE69630964T2 DE 69630964 T2 DE69630964 T2 DE 69630964T2 DE 69630964 T DE69630964 T DE 69630964T DE 69630964 T DE69630964 T DE 69630964T DE 69630964 T2 DE69630964 T2 DE 69630964T2
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- Prior art keywords
- salt
- amorphous state
- acid
- soluble
- substance
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- External Artificial Organs (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
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| US5705190A (en) * | 1995-12-19 | 1998-01-06 | Abbott Laboratories | Controlled release formulation for poorly soluble basic drugs |
-
1996
- 1996-08-07 TW TW085109577A patent/TW487582B/zh not_active IP Right Cessation
- 1996-08-08 AU AU66693/96A patent/AU702088B2/en not_active Ceased
- 1996-08-08 EP EP03016608A patent/EP1356807A3/en not_active Withdrawn
- 1996-08-08 AT AT96926600T patent/ATE255405T1/de not_active IP Right Cessation
- 1996-08-08 KR KR1019980700496A patent/KR100498813B1/ko not_active Expired - Fee Related
- 1996-08-08 WO PCT/JP1996/002246 patent/WO1997006781A1/ja not_active Ceased
- 1996-08-08 US US09/011,060 patent/US6462093B1/en not_active Expired - Fee Related
- 1996-08-08 DE DE69630964T patent/DE69630964T2/de not_active Expired - Lifetime
- 1996-08-08 CA CA002228907A patent/CA2228907A1/en not_active Abandoned
- 1996-08-08 CN CN96196203A patent/CN1089232C/zh not_active Expired - Fee Related
- 1996-08-08 CZ CZ0032698A patent/CZ296072B6/cs not_active IP Right Cessation
- 1996-08-08 EP EP96926600A patent/EP0852140B1/en not_active Expired - Lifetime
- 1996-08-08 NZ NZ315089A patent/NZ315089A/xx unknown
-
1998
- 1998-01-26 MX MX9800717A patent/MX9800717A/es not_active IP Right Cessation
- 1998-02-09 NO NO19980549A patent/NO320486B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2228907A1 (en) | 1997-02-27 |
| NO980549L (no) | 1998-04-02 |
| MX9800717A (es) | 1998-11-30 |
| AU6669396A (en) | 1997-03-12 |
| EP0852140A4 (enExample) | 1998-07-29 |
| CZ32698A3 (cs) | 1998-06-17 |
| KR19990035836A (ko) | 1999-05-25 |
| TW487582B (en) | 2002-05-21 |
| EP1356807A2 (en) | 2003-10-29 |
| EP1356807A3 (en) | 2004-01-28 |
| JPWO9706781A1 (enExample) | 1997-02-27 |
| CN1089232C (zh) | 2002-08-21 |
| WO1997006781A1 (en) | 1997-02-27 |
| AU702088B2 (en) | 1999-02-11 |
| DE69630964D1 (de) | 2004-01-15 |
| KR100498813B1 (ko) | 2006-02-28 |
| NO320486B1 (no) | 2005-12-12 |
| NZ315089A (en) | 1999-06-29 |
| EP0852140B1 (en) | 2003-12-03 |
| EP0852140A1 (en) | 1998-07-08 |
| CZ296072B6 (cs) | 2006-01-11 |
| CN1192677A (zh) | 1998-09-09 |
| ATE255405T1 (de) | 2003-12-15 |
| NO980549D0 (no) | 1998-02-09 |
| US6462093B1 (en) | 2002-10-08 |
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| 8364 | No opposition during term of opposition |