DE69022452T2 - Direktkomprimierte Cholestyramintablette und lösungsmittelfreier Überzug dafür. - Google Patents

Direktkomprimierte Cholestyramintablette und lösungsmittelfreier Überzug dafür.

Info

Publication number
DE69022452T2
DE69022452T2 DE69022452T DE69022452T DE69022452T2 DE 69022452 T2 DE69022452 T2 DE 69022452T2 DE 69022452 T DE69022452 T DE 69022452T DE 69022452 T DE69022452 T DE 69022452T DE 69022452 T2 DE69022452 T2 DE 69022452T2
Authority
DE
Germany
Prior art keywords
solvent
free coating
directly compressed
coating therefor
cholestyramine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69022452T
Other languages
English (en)
Other versions
DE69022452D1 (de
Inventor
Robert J Bequette
Bruce A Bonenberger
Claude E Gallian
John R Reckelhoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DE69022452D1 publication Critical patent/DE69022452D1/de
Publication of DE69022452T2 publication Critical patent/DE69022452T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DE69022452T 1989-03-16 1990-03-15 Direktkomprimierte Cholestyramintablette und lösungsmittelfreier Überzug dafür. Expired - Lifetime DE69022452T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/324,167 US4956182A (en) 1989-03-16 1989-03-16 Direct compression cholestyramine tablet and solvent-free coating therefor

Publications (2)

Publication Number Publication Date
DE69022452D1 DE69022452D1 (de) 1995-10-26
DE69022452T2 true DE69022452T2 (de) 1996-03-14

Family

ID=23262387

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69022452T Expired - Lifetime DE69022452T2 (de) 1989-03-16 1990-03-15 Direktkomprimierte Cholestyramintablette und lösungsmittelfreier Überzug dafür.

Country Status (34)

Country Link
US (1) US4956182A (de)
EP (1) EP0387885B1 (de)
JP (1) JP2974719B2 (de)
KR (1) KR0140211B1 (de)
CN (1) CN1047935C (de)
AR (1) AR246012A1 (de)
AT (1) ATE128031T1 (de)
AU (1) AU617601B2 (de)
BG (1) BG60501B1 (de)
CA (1) CA2012300A1 (de)
CS (1) CS277488B6 (de)
CY (1) CY1899A (de)
DD (1) DD292837A5 (de)
DE (1) DE69022452T2 (de)
DK (1) DK0387885T3 (de)
EG (1) EG19669A (de)
ES (1) ES2078917T3 (de)
FI (1) FI92464C (de)
GR (1) GR3017460T3 (de)
HK (1) HK51396A (de)
HU (1) HU209958B (de)
IE (1) IE70591B1 (de)
IL (1) IL93720A0 (de)
MY (1) MY109744A (de)
NO (1) NO176043C (de)
NZ (1) NZ232864A (de)
OA (1) OA09198A (de)
PL (1) PL163301B1 (de)
PT (1) PT93452B (de)
RO (1) RO106953B1 (de)
RU (1) RU2069558C1 (de)
YU (1) YU52390A (de)
ZA (1) ZA902001B (de)
ZW (1) ZW1890A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5372823A (en) * 1989-03-16 1994-12-13 Bristol-Myers Squibb Company Direct compression cholestyramine tablet and solvent-free coating thereof
US5262167A (en) * 1990-12-20 1993-11-16 Basf Corporation Edible, non-baked low moisture cholestyramine composition
CA2129079C (en) * 1993-08-03 2006-01-17 Tatsuo Nomura Orally administrable cholesterol lowering agent
DE69530308T2 (de) * 1994-09-22 2003-10-16 Akzo Nobel Nv Verfahren zur herstellung von dosierungsformen durch feuchtgranulierung
TW592727B (en) * 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
PT1126826E (pt) 1998-11-02 2008-11-25 Elan Pharma Int Ltd Composição de metilfenidato de libertação modificada multiparticulada
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
US20020054903A1 (en) * 1999-10-19 2002-05-09 Joseph Tyler Direct compression polymer tablet core
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
EP1623703B1 (de) 1999-10-29 2011-10-05 Euro-Celtique S.A. Hydrocodon-Formulierungen mit gesteuerter Freisetzung
HU230686B1 (en) 2000-10-30 2017-08-28 Euro Celtique Sa Controlled release hydrocodone compositions
KR20040058103A (ko) * 2001-02-13 2004-07-03 아스트라제네카 아베 신규 개질 방출 제제
CA2461354C (en) 2001-09-28 2010-04-27 Mcneil-Ppc, Inc. Fondant-based pharmaceutical composition
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US7323192B2 (en) * 2001-09-28 2008-01-29 Mcneil-Ppc, Inc. Immediate release tablet
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
US6982094B2 (en) 2001-09-28 2006-01-03 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US7807197B2 (en) 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
ES2400186T3 (es) * 2004-05-24 2013-04-08 Mepha Schweiz Ag Procedimiento para recubrimiento en seco
ES2317313T3 (es) * 2004-10-19 2009-04-16 Krka, Tovarna Zdravil, D.D., Novo Mesto Composicion farmaceutica solida que comprende clorhidrato de donepezilo.
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
US20060177415A1 (en) * 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
CA2620406A1 (en) 2005-09-02 2007-03-08 Genzyme Corporation Method for removing phosphate and polymer used therefore
PL1924246T3 (pl) 2005-09-15 2016-04-29 Genzyme Corp Preparat polimerów amin w saszetkach
DE102005060377A1 (de) * 2005-12-16 2007-06-21 Ratiopharm Gmbh Pharmazeutische Zusammensetzung enthaltend Donepezilhydrochlorid, Tablette hieraus und Verfahren zu deren Herstellung
JP5301273B2 (ja) 2006-08-09 2013-09-25 田辺三菱製薬株式会社 錠剤
BRPI0717545A2 (pt) 2006-09-29 2013-10-22 Gezyme Corp Composição farmacêutica, método para tratar uma doença, polímero de amida, rede de polímero, e, método para preparar um polímero de amida
US8163799B2 (en) 2006-12-14 2012-04-24 Genzyme Corporation Amido-amine polymer compositions
MX356111B (es) 2012-04-18 2018-05-15 SpecGx LLC Composiciones farmaceuticas disuasorias de abuso, de liberacion inmediata.
WO2015059830A1 (ja) 2013-10-25 2015-04-30 株式会社クラレ 複層フィルム及びそれからなる合わせガラス用中間膜
WO2016004170A1 (en) * 2014-07-03 2016-01-07 Mallinckrodt Llc Abuse deterrent immediate release formulations comprising non-cellulose polysaccharides
RU2750944C2 (ru) * 2016-02-09 2021-07-06 Альбирео Аб Пероральный состав холестирамина и его применение
WO2017138876A1 (en) * 2016-02-09 2017-08-17 Albireo Ab Cholestyramine pellets and methods for preparation thereof
EP3856160A4 (de) 2018-09-25 2022-07-06 SpecGx LLC Missbrauchssichere kapseldarreichungsformen mit sofortiger freisetzung
CN114053234A (zh) * 2021-12-29 2022-02-18 江苏省药物研究所有限公司 一种阿卡波糖片及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB595444A (en) * 1945-07-09 1947-12-04 Gwilym Lloyd Thomas Improvements in or relating to medicaments, and to the preparation thereof
US3383237A (en) * 1964-01-29 1968-05-14 Richardson Merrell Inc Tablet coating
JPS56140915A (en) * 1980-04-07 1981-11-04 Yamanouchi Pharmaceut Co Ltd Pharmaceutical preparation for solid drug
US4895723A (en) * 1986-09-08 1990-01-23 Amer And Company Cholestyramine compositions and method for preparation thereof
ZA876640B (en) * 1986-09-26 1988-03-08 Warner-Lambert Company Treated lipid regulator
IT1200217B (it) * 1986-09-30 1989-01-05 Valducci Roberto Membrana per uso farmaceutico ed industriale

Also Published As

Publication number Publication date
BG91463A (bg) 1993-12-24
RU2069558C1 (ru) 1996-11-27
NO176043B (no) 1994-10-17
PT93452B (pt) 1996-12-31
EG19669A (en) 1995-08-30
EP0387885A2 (de) 1990-09-19
AU5136790A (en) 1990-09-20
RO106953B1 (ro) 1993-08-30
PL163301B1 (en) 1994-03-31
ATE128031T1 (de) 1995-10-15
MY109744A (en) 1997-05-31
PT93452A (pt) 1990-11-07
IL93720A0 (en) 1990-12-23
JPH03236326A (ja) 1991-10-22
CA2012300A1 (en) 1990-09-16
CN1045921A (zh) 1990-10-10
GR3017460T3 (en) 1995-12-31
IE70591B1 (en) 1996-12-11
DK0387885T3 (da) 1995-11-06
NO901183D0 (no) 1990-03-14
US4956182A (en) 1990-09-11
EP0387885A3 (de) 1992-06-17
FI901241A0 (fi) 1990-03-13
NZ232864A (en) 1992-04-28
KR0140211B1 (ko) 1998-06-01
JP2974719B2 (ja) 1999-11-10
AR246012A1 (es) 1994-03-30
ZA902001B (en) 1990-11-28
YU52390A (en) 1991-10-31
FI92464C (fi) 1994-11-25
DE69022452D1 (de) 1995-10-26
DD292837A5 (de) 1991-08-14
CY1899A (en) 1990-03-15
HK51396A (en) 1996-03-29
HU209958B (en) 1994-12-28
BG60501B1 (bg) 1995-06-30
AU617601B2 (en) 1991-11-28
NO901183L (no) 1990-09-17
HUT54489A (en) 1991-03-28
ZW1890A1 (en) 1990-10-31
KR900013946A (ko) 1990-10-22
EP0387885B1 (de) 1995-09-20
CN1047935C (zh) 2000-01-05
HU901429D0 (en) 1990-06-28
IE900941L (en) 1990-09-16
OA09198A (fr) 1992-06-30
ES2078917T3 (es) 1996-01-01
NO176043C (no) 1995-01-25
CS277488B6 (en) 1993-03-17
FI92464B (fi) 1994-08-15

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Legal Events

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8364 No opposition during term of opposition