MX356111B - Composiciones farmaceuticas disuasorias de abuso, de liberacion inmediata. - Google Patents
Composiciones farmaceuticas disuasorias de abuso, de liberacion inmediata.Info
- Publication number
- MX356111B MX356111B MX2014009876A MX2014009876A MX356111B MX 356111 B MX356111 B MX 356111B MX 2014009876 A MX2014009876 A MX 2014009876A MX 2014009876 A MX2014009876 A MX 2014009876A MX 356111 B MX356111 B MX 356111B
- Authority
- MX
- Mexico
- Prior art keywords
- pharmaceutical compositions
- immediate release
- abuse deterrent
- deterrent pharmaceutical
- molecular weight
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 4
- 239000012729 immediate-release (IR) formulation Substances 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 229920001477 hydrophilic polymer Polymers 0.000 abstract 2
- 239000007909 solid dosage form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Addiction (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente descripción proporciona composiciones farmacéuticas y procesos para preparar composiciones farmacéuticas en forma de dosis sólida que proporcionan liberación inmediata de los principios activos y tienen propiedades disuasorias de abuso. Las composiciones farmacéuticas proporcionadas en la presente comprende al menos un principio farmacéuticamente activo, al menos un polímero hidrófilo de bajo peso molecular, al menos un polímero hidrófilo de alto peso molecular, y un sistema efervescente.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261625926P | 2012-04-18 | 2012-04-18 | |
| US201361792478P | 2013-03-15 | 2013-03-15 | |
| PCT/US2013/037056 WO2013158814A1 (en) | 2012-04-18 | 2013-04-18 | Immediate release, abuse deterrent pharmaceutical compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014009876A MX2014009876A (es) | 2014-11-13 |
| MX356111B true MX356111B (es) | 2018-05-15 |
Family
ID=48227563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014009876A MX356111B (es) | 2012-04-18 | 2013-04-18 | Composiciones farmaceuticas disuasorias de abuso, de liberacion inmediata. |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US9993422B2 (es) |
| EP (1) | EP2838516B1 (es) |
| JP (1) | JP6067100B2 (es) |
| BR (1) | BR112014024382B1 (es) |
| CA (1) | CA2864738C (es) |
| ES (1) | ES2699806T3 (es) |
| IL (1) | IL234997B (es) |
| MX (1) | MX356111B (es) |
| PL (1) | PL2838516T3 (es) |
| WO (1) | WO2013158814A1 (es) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9993422B2 (en) | 2012-04-18 | 2018-06-12 | SpecGx LLC | Immediate release, abuse deterrent pharmaceutical compositions |
| ES2698611T3 (es) | 2012-07-12 | 2019-02-05 | SpecGx LLC | Composiciones farmacéuticas disuasorias del abuso y de liberación prolongada |
| WO2014152296A1 (en) | 2013-03-15 | 2014-09-25 | Mallinckrodt Llc | Abuse deterrent solid dosage form for immediate release with functional score |
| CA3042642A1 (en) * | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| US9770514B2 (en) | 2013-09-03 | 2017-09-26 | ExxPharma Therapeutics LLC | Tamper-resistant pharmaceutical dosage forms |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| PT3164117T (pt) | 2014-07-03 | 2023-12-12 | SpecGx LLC | Formulações de libertação imediata de dissuasão de abuso compreendendo polissacáridos não celulósicos |
| ES2809458T3 (es) * | 2014-07-17 | 2021-03-04 | Pharmaceutical Manufacturing Res Services Inc | Forma de dosificación llena de líquido, disuasoria del abuso y de liberación inmediata |
| EP3209282A4 (en) | 2014-10-20 | 2018-05-23 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| WO2016199170A2 (en) * | 2015-06-10 | 2016-12-15 | Cipla Limited | Paliperidone palmitate particles and compositions thereof |
| US9861629B1 (en) | 2015-10-07 | 2018-01-09 | Banner Life Sciences Llc | Opioid abuse deterrent dosage forms |
| JP2019504072A (ja) | 2016-02-08 | 2019-02-14 | スペックジーエックス エルエルシー | 徐放性及び濫用抑止特性を有するグルコマンナン含有医薬組成物 |
| US10213511B2 (en) | 2016-03-02 | 2019-02-26 | Frequency Therapeutics, Inc. | Thermoreversible compositions for administration of therapeutic agents |
| US10201540B2 (en) | 2016-03-02 | 2019-02-12 | Frequency Therapeutics, Inc. | Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: I |
| US10335405B1 (en) | 2016-05-04 | 2019-07-02 | Patheon Softgels, Inc. | Non-burst releasing pharmaceutical composition |
| CN110035740B (zh) | 2016-11-02 | 2023-08-04 | 中枢疗法公司 | 稳定的水性辣椒素可注射制剂及其医学用途 |
| US10335375B2 (en) | 2017-05-30 | 2019-07-02 | Patheon Softgels, Inc. | Anti-overingestion abuse deterrent compositions |
| MX2020000488A (es) | 2017-07-20 | 2020-10-28 | Centrexion Therapeutics Corp | Metodos y composiciones para el tratamiento del dolor usando capsaicina. |
| EP3473246A1 (en) | 2017-10-19 | 2019-04-24 | Capsugel Belgium NV | Immediate release abuse deterrent formulations |
| WO2019126125A1 (en) | 2017-12-20 | 2019-06-27 | Purdue Pharma L.P. | Abuse deterrent morphine sulfate dosage forms |
| CA3112030A1 (en) | 2018-09-25 | 2020-04-02 | SpecGx LLC | Abuse deterrent immediate release capsule dosage forms |
| CN114555031A (zh) * | 2019-08-27 | 2022-05-27 | 应用材料公司 | 用于药物防滥用制剂的气相包衣技术 |
| KR102603701B1 (ko) * | 2020-12-04 | 2023-11-17 | 한국생산기술연구원 | 팽창성 창상피복재 및 이의 제조방법 |
Family Cites Families (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2211485A (en) * | 1940-08-13 | Effervescent acetyl salicylic acid | ||
| JPS537495B2 (es) | 1973-05-21 | 1978-03-18 | ||
| US3980766A (en) | 1973-08-13 | 1976-09-14 | West Laboratories, Inc. | Orally administered drug composition for therapy in the treatment of narcotic drug addiction |
| DE2530563C2 (de) | 1975-07-09 | 1986-07-24 | Bayer Ag, 5090 Leverkusen | Analgetische Arzneimittel mit vermindertem Mißbrauchspotential |
| US4678661A (en) | 1983-09-28 | 1987-07-07 | Gerhard Gergely | Effervescent composition and method of making same |
| JPH0747532B2 (ja) | 1985-10-16 | 1995-05-24 | 花王株式会社 | 錠剤の製造方法 |
| US4956182A (en) | 1989-03-16 | 1990-09-11 | Bristol-Myers Company | Direct compression cholestyramine tablet and solvent-free coating therefor |
| GB9401894D0 (en) | 1994-02-01 | 1994-03-30 | Rhone Poulenc Rorer Ltd | New compositions of matter |
| US6071539A (en) * | 1996-09-20 | 2000-06-06 | Ethypharm, Sa | Effervescent granules and methods for their preparation |
| US6200604B1 (en) | 1998-03-27 | 2001-03-13 | Cima Labs Inc. | Sublingual buccal effervescent |
| JP5026635B2 (ja) | 1998-09-10 | 2012-09-12 | ニュコメデ ダンマルク アンパーツセルスカブ | 医薬物質の迅速放出医薬組成物 |
| US20080102121A1 (en) | 1998-11-02 | 2008-05-01 | Elan Pharma International Limited | Compositions comprising nanoparticulate meloxicam and controlled release hydrocodone |
| US6264981B1 (en) | 1999-10-27 | 2001-07-24 | Anesta Corporation | Oral transmucosal drug dosage using solid solution |
| US6541025B1 (en) | 1999-12-30 | 2003-04-01 | Shear/Kershman Laboratories, Inc. | Method for preparing solid delivery system for encapsulated and non-encapsulated pharmaceuticals |
| US6340471B1 (en) | 1999-12-30 | 2002-01-22 | Alvin Kershman | Method for preparing solid delivery system for encapsulated and non-encapsulated pharmaceuticals |
| US6660302B1 (en) | 2000-09-06 | 2003-12-09 | Chr. Hansen, Inc. | Dry-powder film coating composition and method of preparation |
| US20030068375A1 (en) | 2001-08-06 | 2003-04-10 | Curtis Wright | Pharmaceutical formulation containing gelling agent |
| US20080050422A1 (en) | 2001-10-12 | 2008-02-28 | Monosolrx, Llc. | Method of administering a film product containing a drug |
| WO2003032954A1 (en) | 2001-10-17 | 2003-04-24 | Dr. Reddy's Laboratories Ltd. | Stabilized pharmaceutical formulations containing amlodipine maleate |
| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| US20040005359A1 (en) | 2002-06-27 | 2004-01-08 | Cheng Xiu Xiu | Controlled release oral dosage form |
| US20040202717A1 (en) | 2003-04-08 | 2004-10-14 | Mehta Atul M. | Abuse-resistant oral dosage forms and method of use thereof |
| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| DE102004020220A1 (de) | 2004-04-22 | 2005-11-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
| US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
| ATE365545T1 (de) | 2003-08-06 | 2007-07-15 | Gruenenthal Gmbh | Gegen missbrauch gesicherte darreichungsform |
| DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| DE102004032051A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
| WO2005034920A1 (en) | 2003-10-10 | 2005-04-21 | Lifecycle Pharma A/S | A solid dosage form comprising a fibrate |
| US20050245557A1 (en) | 2003-10-15 | 2005-11-03 | Pain Therapeutics, Inc. | Methods and materials useful for the treatment of arthritic conditions, inflammation associated with a chronic condition or chronic pain |
| US7201920B2 (en) | 2003-11-26 | 2007-04-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of opioid containing dosage forms |
| AU2013206525B2 (en) | 2003-11-26 | 2015-09-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of opioid containing dosage forms |
| US20050165038A1 (en) | 2004-01-22 | 2005-07-28 | Maxwell Gordon | Analgetic dosage forms that are resistant to parenteral and inhalation dosing and have reduced side effects |
| DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
| US8093408B2 (en) | 2005-06-21 | 2012-01-10 | The Company Wockhardt | Antidepressant oral pharmaceutical compositions |
| US20070020186A1 (en) | 2005-07-22 | 2007-01-25 | Alpex Pharma S.A. | Solid dosage formulations of narcotic drugs having improved buccal adsorption |
| PL116330U1 (en) | 2005-10-31 | 2007-04-02 | Alza Corp | Method for the reduction of alcohol provoked rapid increase in the released dose of the orally administered opioide with prolonged liberation |
| US8329744B2 (en) | 2005-11-02 | 2012-12-11 | Relmada Therapeutics, Inc. | Methods of preventing the serotonin syndrome and compositions for use thereof |
| US8652529B2 (en) | 2005-11-10 | 2014-02-18 | Flamel Technologies | Anti-misuse microparticulate oral pharmaceutical form |
| US20090317355A1 (en) | 2006-01-21 | 2009-12-24 | Abbott Gmbh & Co. Kg, | Abuse resistant melt extruded formulation having reduced alcohol interaction |
| EP2428205B1 (en) | 2006-03-16 | 2012-10-03 | Tris Pharma, Inc. | Modified release formulations containing drug-ion exchange resin complexes |
| WO2007112286A2 (en) | 2006-03-24 | 2007-10-04 | Auxilium Pharmaceuticals, Inc. | Stabilized compositions containing alkaline labile drugs |
| US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
| ES2300188B1 (es) | 2006-05-24 | 2009-05-01 | Ferrer Internacional, S.A. | Comprimido bicapa para la prevencion de los accidentes cardiovasculares. |
| US20080069891A1 (en) | 2006-09-15 | 2008-03-20 | Cima Labs, Inc. | Abuse resistant drug formulation |
| US20080069871A1 (en) | 2006-07-21 | 2008-03-20 | Vaughn Jason M | Hydrophobic abuse deterrent delivery system |
| SA07280459B1 (ar) | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
| EP2104493A2 (en) | 2007-01-16 | 2009-09-30 | Egalet A/S | Use of i) a polyglycol and n) an active drug substance for the preparation of a pharmaceutical composition for i) mitigating the risk of alcohol induced dose dumping and/or ii) reducing the risk of drug abuse |
| KR101612901B1 (ko) | 2007-03-02 | 2016-04-15 | 테이카 세이야쿠 가부시키가이샤 | 경피흡수 의약조성물, 의약조성물 저장유닛 및 이것을 이용하는 경피흡수제제 |
| CA2684219C (en) | 2007-04-13 | 2017-05-23 | Chemgenex Pharmaceuticals, Inc. | Oral cephalotaxine dosage forms |
| KR20100032883A (ko) * | 2007-06-07 | 2010-03-26 | 사토 세이야쿠 가부시키가이샤 | 속용성 및 가요성을 가진 필름제제 |
| US20090124650A1 (en) | 2007-06-21 | 2009-05-14 | Endo Pharmaceuticals, Inc. | Method of Treating Pain Utilizing Controlled Release Oxymorphone Pharmaceutical Compositions and Instructions on Effects of Alcohol |
| WO2009023672A2 (en) | 2007-08-13 | 2009-02-19 | Abuse Deterrent Pharmaceutical Llc | Abuse resistant drugs, method of use and method of making |
| CA2700426C (en) | 2007-09-25 | 2017-10-31 | Galia Temtsin Krayz | Compositions comprising lipophilic active compounds and method for their preparation |
| CA2707980C (en) | 2007-12-17 | 2015-05-12 | Labopharm Inc. | Misuse preventative, controlled release formulation |
| WO2009092601A1 (en) | 2008-01-25 | 2009-07-30 | Grünenthal GmbH | Pharmaceutical dosage form |
| US8729070B2 (en) | 2008-02-20 | 2014-05-20 | Targia Pharmaceuticals | CNS pharmaceutical compositions and methods of use |
| EP2484664B1 (en) | 2008-05-07 | 2013-09-04 | Dainippon Sumitomo Pharma Co., Ltd. | Cyclic amine-1-carboxylic acid ester derivative and pharmaceutical composition containing the same |
| AU2009294308B2 (en) | 2008-09-18 | 2013-05-30 | Purdue Pharma L.P. | Pharmaceutical dosage forms comprising poly(e-caprolactone) |
| US20110268666A1 (en) | 2008-09-29 | 2011-11-03 | Yissum Research Development Company of the Research University of Jerusalem, Ltd. | Novel gastroretentive delivery system |
| NZ594207A (en) | 2009-02-06 | 2013-03-28 | Egalet Ltd | Immediate release composition resistant to abuse by intake of alcohol |
| PE20120572A1 (es) | 2009-07-22 | 2012-06-06 | Gruenenthal Chemie | Forma de dosificacion de oxidacion estabilizada resistente a la manipulacion |
| JP5017516B2 (ja) | 2009-11-13 | 2012-09-05 | 株式会社ホットアルバム炭酸泉タブレット | 錠剤の製造方法 |
| WO2011066980A2 (en) | 2009-12-04 | 2011-06-09 | Lars Holger Hermann | Oral dosage forms with reduced potential for drug abuse |
| WO2011079074A1 (en) * | 2009-12-24 | 2011-06-30 | Acura Phamaceuticals, Inc. | Pharmaceutical compositions for deterring misuse, abuse, and diversion |
| US20120321674A1 (en) | 2011-02-17 | 2012-12-20 | Michael Vachon | Technology for Preventing Abuse of Solid Dosage Forms |
| TWI516286B (zh) | 2010-09-02 | 2016-01-11 | 歌林達股份有限公司 | 含陰離子聚合物之抗破碎劑型 |
| CA2827273A1 (en) | 2011-02-17 | 2012-08-23 | QRxPharma Ltd. | Technology for preventing abuse of solid dosage forms |
| EP2782558A4 (en) | 2011-11-22 | 2015-03-18 | Watson Pharmaceuticals Inc | MISSABLE TABLET WITH IMMEDIATE RELEASE |
| US9993422B2 (en) | 2012-04-18 | 2018-06-12 | SpecGx LLC | Immediate release, abuse deterrent pharmaceutical compositions |
| CA2868416A1 (en) | 2012-04-18 | 2013-10-24 | Mallinckrodt Llc | Immediate release pharmaceutical compositions with abuse deterrent properties |
| ES2698611T3 (es) | 2012-07-12 | 2019-02-05 | SpecGx LLC | Composiciones farmacéuticas disuasorias del abuso y de liberación prolongada |
| WO2014152296A1 (en) | 2013-03-15 | 2014-09-25 | Mallinckrodt Llc | Abuse deterrent solid dosage form for immediate release with functional score |
| PT3164117T (pt) | 2014-07-03 | 2023-12-12 | SpecGx LLC | Formulações de libertação imediata de dissuasão de abuso compreendendo polissacáridos não celulósicos |
-
2013
- 2013-04-18 US US13/865,286 patent/US9993422B2/en active Active
- 2013-04-18 JP JP2015507160A patent/JP6067100B2/ja active Active
- 2013-04-18 PL PL13719672T patent/PL2838516T3/pl unknown
- 2013-04-18 CA CA2864738A patent/CA2864738C/en active Active
- 2013-04-18 EP EP13719672.1A patent/EP2838516B1/en active Active
- 2013-04-18 WO PCT/US2013/037056 patent/WO2013158814A1/en not_active Ceased
- 2013-04-18 BR BR112014024382-4A patent/BR112014024382B1/pt active IP Right Grant
- 2013-04-18 ES ES13719672T patent/ES2699806T3/es active Active
- 2013-04-18 MX MX2014009876A patent/MX356111B/es active IP Right Grant
-
2014
- 2014-10-05 IL IL234997A patent/IL234997B/en active IP Right Grant
-
2017
- 2017-09-25 US US15/714,137 patent/US20180008532A1/en not_active Abandoned
-
2018
- 2018-05-11 US US15/977,415 patent/US20180256493A1/en not_active Abandoned
- 2018-06-07 US US16/002,190 patent/US20180280289A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ES2699806T3 (es) | 2019-02-12 |
| US20180008532A1 (en) | 2018-01-11 |
| US9993422B2 (en) | 2018-06-12 |
| US20180280289A1 (en) | 2018-10-04 |
| IL234997B (en) | 2019-02-28 |
| CA2864738C (en) | 2017-07-18 |
| CA2864738A1 (en) | 2013-10-24 |
| PL2838516T3 (pl) | 2019-05-31 |
| US20130280177A1 (en) | 2013-10-24 |
| EP2838516A1 (en) | 2015-02-25 |
| EP2838516B1 (en) | 2018-10-17 |
| JP6067100B2 (ja) | 2017-01-25 |
| MX2014009876A (es) | 2014-11-13 |
| BR112014024382A2 (es) | 2017-06-20 |
| JP2015514775A (ja) | 2015-05-21 |
| WO2013158814A1 (en) | 2013-10-24 |
| US20180256493A1 (en) | 2018-09-13 |
| WO2013158814A8 (en) | 2014-06-19 |
| BR112014024382B1 (pt) | 2022-08-09 |
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