ES2078917T3 - Comprimido de colestiramina por compresion directa y recubrimiento exento de disolvente para el mismo. - Google Patents

Comprimido de colestiramina por compresion directa y recubrimiento exento de disolvente para el mismo.

Info

Publication number
ES2078917T3
ES2078917T3 ES90104945T ES90104945T ES2078917T3 ES 2078917 T3 ES2078917 T3 ES 2078917T3 ES 90104945 T ES90104945 T ES 90104945T ES 90104945 T ES90104945 T ES 90104945T ES 2078917 T3 ES2078917 T3 ES 2078917T3
Authority
ES
Spain
Prior art keywords
cholestiramine
tablet
solvent
same
direct compression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90104945T
Other languages
English (en)
Inventor
Robert J Bequette
Bruce A Bonenberger
Claude E Gallian
John R Reckelhoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ES2078917T3 publication Critical patent/ES2078917T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Abstract

EL NUCLEO INTERNO DE LA PASTILLA ESTA FORMADO DE AGLOMERANTES DE CLOLESTIRAMINA QUE CONSISTEN EN NUMEROSAS, PEQUEÑAS Y DE FORMA IRREGULAR FRAGMENTOS DE BORDES DENTADOS QUE TIENEN SUPERFICIES POCO LISAS O GRASAS CON UN CONTENIDO EN HIDRATANTE DE 8 A 14% EN PESO. LA COBERTURA COMPRENDE DE UN 60 A UN 95% EN PESO DE UN ACIDO ESTEARICO Y DE UN 5 A 40% DE GLICOL PLIETILENO.
ES90104945T 1989-03-16 1990-03-15 Comprimido de colestiramina por compresion directa y recubrimiento exento de disolvente para el mismo. Expired - Lifetime ES2078917T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/324,167 US4956182A (en) 1989-03-16 1989-03-16 Direct compression cholestyramine tablet and solvent-free coating therefor

Publications (1)

Publication Number Publication Date
ES2078917T3 true ES2078917T3 (es) 1996-01-01

Family

ID=23262387

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90104945T Expired - Lifetime ES2078917T3 (es) 1989-03-16 1990-03-15 Comprimido de colestiramina por compresion directa y recubrimiento exento de disolvente para el mismo.

Country Status (34)

Country Link
US (1) US4956182A (es)
EP (1) EP0387885B1 (es)
JP (1) JP2974719B2 (es)
KR (1) KR0140211B1 (es)
CN (1) CN1047935C (es)
AR (1) AR246012A1 (es)
AT (1) ATE128031T1 (es)
AU (1) AU617601B2 (es)
BG (1) BG60501B1 (es)
CA (1) CA2012300A1 (es)
CS (1) CS277488B6 (es)
CY (1) CY1899A (es)
DD (1) DD292837A5 (es)
DE (1) DE69022452T2 (es)
DK (1) DK0387885T3 (es)
EG (1) EG19669A (es)
ES (1) ES2078917T3 (es)
FI (1) FI92464C (es)
GR (1) GR3017460T3 (es)
HK (1) HK51396A (es)
HU (1) HU209958B (es)
IE (1) IE70591B1 (es)
IL (1) IL93720A0 (es)
MY (1) MY109744A (es)
NO (1) NO176043C (es)
NZ (1) NZ232864A (es)
OA (1) OA09198A (es)
PL (1) PL163301B1 (es)
PT (1) PT93452B (es)
RO (1) RO106953B1 (es)
RU (1) RU2069558C1 (es)
YU (1) YU52390A (es)
ZA (1) ZA902001B (es)
ZW (1) ZW1890A1 (es)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5372823A (en) * 1989-03-16 1994-12-13 Bristol-Myers Squibb Company Direct compression cholestyramine tablet and solvent-free coating thereof
US5262167A (en) * 1990-12-20 1993-11-16 Basf Corporation Edible, non-baked low moisture cholestyramine composition
CA2129079C (en) * 1993-08-03 2006-01-17 Tatsuo Nomura Orally administrable cholesterol lowering agent
DE69530308T2 (de) * 1994-09-22 2003-10-16 Akzo Nobel Nv Verfahren zur herstellung von dosierungsformen durch feuchtgranulierung
TW592727B (en) * 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
WO2000025752A1 (en) 1998-11-02 2000-05-11 Church, Marla, J. Multiparticulate modified release composition
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
US20020054903A1 (en) * 1999-10-19 2002-05-09 Joseph Tyler Direct compression polymer tablet core
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
CN102716101A (zh) 1999-10-29 2012-10-10 欧罗赛铁克股份有限公司 控释氢可酮制剂
EP2283829A1 (en) 2000-10-30 2011-02-16 Euro-Celtique S.A. Controlled release hydrocodone formulations
CN1491105A (zh) * 2001-02-13 2004-04-21 新的改进释放的制剂
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
JP2005529059A (ja) 2001-09-28 2005-09-29 マクニール−ピーピーシー・インコーポレイテッド 改質した放出用の投薬形態
US7323192B2 (en) * 2001-09-28 2008-01-29 Mcneil-Ppc, Inc. Immediate release tablet
US6982094B2 (en) 2001-09-28 2006-01-03 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US7807197B2 (en) 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
ES2400186T3 (es) * 2004-05-24 2013-04-08 Mepha Schweiz Ag Procedimiento para recubrimiento en seco
EP1811957B1 (en) * 2004-10-19 2008-11-26 KRKA, tovarna zdravil, d.d., Novo mesto Solid pharmaceutical composition comprising donepezil hydrochloride
US20060177415A1 (en) * 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
EP1951266A2 (en) 2005-09-02 2008-08-06 Genzyme Corporation Method for removing phosphate and polymer used therefore
JP5595660B2 (ja) 2005-09-15 2014-09-24 ジェンザイム コーポレーション アミンポリマー用サシェ製剤
DE102005060377A1 (de) * 2005-12-16 2007-06-21 Ratiopharm Gmbh Pharmazeutische Zusammensetzung enthaltend Donepezilhydrochlorid, Tablette hieraus und Verfahren zu deren Herstellung
US20090252794A1 (en) 2006-08-09 2009-10-08 Tetsuya Suzuki Tablet
US8425887B2 (en) 2006-09-29 2013-04-23 Genzyme Corporation Amide dendrimer compositions
WO2008076242A1 (en) 2006-12-14 2008-06-26 Genzyme Corporation Amido-amine polymer compositions
JP6067100B2 (ja) 2012-04-18 2017-01-25 マリンクロッド エルエルシー 即放性乱用抑止医薬組成物
JP5469286B1 (ja) 2013-10-25 2014-04-16 株式会社クラレ 複層フィルム及びそれからなる合わせガラス用中間膜
WO2016004170A1 (en) 2014-07-03 2016-01-07 Mallinckrodt Llc Abuse deterrent immediate release formulations comprising non-cellulose polysaccharides
EP3413875B1 (en) * 2016-02-09 2020-01-29 Albireo AB Cholestyramine pellets and methods for preparation thereof
ES2874669T3 (es) * 2016-02-09 2021-11-05 Albireo Ab Formulación oral de colestiramina y uso de la misma
WO2020068510A1 (en) 2018-09-25 2020-04-02 SpecGx LLC Abuse deterrent immediate release capsule dosage forms
CN114053234A (zh) * 2021-12-29 2022-02-18 江苏省药物研究所有限公司 一种阿卡波糖片及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB595444A (en) * 1945-07-09 1947-12-04 Gwilym Lloyd Thomas Improvements in or relating to medicaments, and to the preparation thereof
US3383237A (en) * 1964-01-29 1968-05-14 Richardson Merrell Inc Tablet coating
JPS56140915A (en) * 1980-04-07 1981-11-04 Yamanouchi Pharmaceut Co Ltd Pharmaceutical preparation for solid drug
US4895723A (en) * 1986-09-08 1990-01-23 Amer And Company Cholestyramine compositions and method for preparation thereof
ZA876640B (en) * 1986-09-26 1988-03-08 Warner-Lambert Company Treated lipid regulator
IT1200217B (it) * 1986-09-30 1989-01-05 Valducci Roberto Membrana per uso farmaceutico ed industriale

Also Published As

Publication number Publication date
AR246012A1 (es) 1994-03-30
OA09198A (fr) 1992-06-30
HK51396A (en) 1996-03-29
KR900013946A (ko) 1990-10-22
PT93452B (pt) 1996-12-31
HU901429D0 (en) 1990-06-28
DD292837A5 (de) 1991-08-14
NO901183L (no) 1990-09-17
FI92464B (fi) 1994-08-15
NO901183D0 (no) 1990-03-14
PL163301B1 (en) 1994-03-31
EP0387885A3 (en) 1992-06-17
EG19669A (en) 1995-08-30
HU209958B (en) 1994-12-28
NO176043B (no) 1994-10-17
NZ232864A (en) 1992-04-28
CS277488B6 (en) 1993-03-17
JP2974719B2 (ja) 1999-11-10
KR0140211B1 (ko) 1998-06-01
DE69022452T2 (de) 1996-03-14
RO106953B1 (ro) 1993-08-30
US4956182A (en) 1990-09-11
CY1899A (en) 1990-03-15
IL93720A0 (en) 1990-12-23
RU2069558C1 (ru) 1996-11-27
MY109744A (en) 1997-05-31
CN1047935C (zh) 2000-01-05
BG60501B1 (bg) 1995-06-30
FI92464C (fi) 1994-11-25
AU617601B2 (en) 1991-11-28
JPH03236326A (ja) 1991-10-22
HUT54489A (en) 1991-03-28
IE900941L (en) 1990-09-16
DK0387885T3 (da) 1995-11-06
DE69022452D1 (de) 1995-10-26
IE70591B1 (en) 1996-12-11
EP0387885A2 (en) 1990-09-19
EP0387885B1 (en) 1995-09-20
NO176043C (no) 1995-01-25
GR3017460T3 (en) 1995-12-31
CA2012300A1 (en) 1990-09-16
AU5136790A (en) 1990-09-20
FI901241A0 (fi) 1990-03-13
ZA902001B (en) 1990-11-28
CN1045921A (zh) 1990-10-10
YU52390A (en) 1991-10-31
ATE128031T1 (de) 1995-10-15
PT93452A (pt) 1990-11-07
ZW1890A1 (en) 1990-10-31

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