ES2078917T3 - Comprimido de colestiramina por compresion directa y recubrimiento exento de disolvente para el mismo. - Google Patents

Comprimido de colestiramina por compresion directa y recubrimiento exento de disolvente para el mismo.

Info

Publication number
ES2078917T3
ES2078917T3 ES90104945T ES90104945T ES2078917T3 ES 2078917 T3 ES2078917 T3 ES 2078917T3 ES 90104945 T ES90104945 T ES 90104945T ES 90104945 T ES90104945 T ES 90104945T ES 2078917 T3 ES2078917 T3 ES 2078917T3
Authority
ES
Spain
Prior art keywords
cholestiramine
tablet
solvent
same
direct compression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90104945T
Other languages
English (en)
Inventor
Robert J Bequette
Bruce A Bonenberger
Claude E Gallian
John R Reckelhoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ES2078917T3 publication Critical patent/ES2078917T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

EL NUCLEO INTERNO DE LA PASTILLA ESTA FORMADO DE AGLOMERANTES DE CLOLESTIRAMINA QUE CONSISTEN EN NUMEROSAS, PEQUEÑAS Y DE FORMA IRREGULAR FRAGMENTOS DE BORDES DENTADOS QUE TIENEN SUPERFICIES POCO LISAS O GRASAS CON UN CONTENIDO EN HIDRATANTE DE 8 A 14% EN PESO. LA COBERTURA COMPRENDE DE UN 60 A UN 95% EN PESO DE UN ACIDO ESTEARICO Y DE UN 5 A 40% DE GLICOL PLIETILENO.
ES90104945T 1989-03-16 1990-03-15 Comprimido de colestiramina por compresion directa y recubrimiento exento de disolvente para el mismo. Expired - Lifetime ES2078917T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/324,167 US4956182A (en) 1989-03-16 1989-03-16 Direct compression cholestyramine tablet and solvent-free coating therefor

Publications (1)

Publication Number Publication Date
ES2078917T3 true ES2078917T3 (es) 1996-01-01

Family

ID=23262387

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90104945T Expired - Lifetime ES2078917T3 (es) 1989-03-16 1990-03-15 Comprimido de colestiramina por compresion directa y recubrimiento exento de disolvente para el mismo.

Country Status (34)

Country Link
US (1) US4956182A (es)
EP (1) EP0387885B1 (es)
JP (1) JP2974719B2 (es)
KR (1) KR0140211B1 (es)
CN (1) CN1047935C (es)
AR (1) AR246012A1 (es)
AT (1) ATE128031T1 (es)
AU (1) AU617601B2 (es)
BG (1) BG60501B1 (es)
CA (1) CA2012300A1 (es)
CS (1) CS277488B6 (es)
CY (1) CY1899A (es)
DD (1) DD292837A5 (es)
DE (1) DE69022452T2 (es)
DK (1) DK0387885T3 (es)
EG (1) EG19669A (es)
ES (1) ES2078917T3 (es)
FI (1) FI92464C (es)
GR (1) GR3017460T3 (es)
HK (1) HK51396A (es)
HU (1) HU209958B (es)
IE (1) IE70591B1 (es)
IL (1) IL93720A0 (es)
MY (1) MY109744A (es)
NO (1) NO176043C (es)
NZ (1) NZ232864A (es)
OA (1) OA09198A (es)
PL (1) PL163301B1 (es)
PT (1) PT93452B (es)
RO (1) RO106953B1 (es)
RU (1) RU2069558C1 (es)
YU (1) YU52390A (es)
ZA (1) ZA902001B (es)
ZW (1) ZW1890A1 (es)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5372823A (en) * 1989-03-16 1994-12-13 Bristol-Myers Squibb Company Direct compression cholestyramine tablet and solvent-free coating thereof
US5262167A (en) * 1990-12-20 1993-11-16 Basf Corporation Edible, non-baked low moisture cholestyramine composition
CA2129079C (en) * 1993-08-03 2006-01-17 Tatsuo Nomura Orally administrable cholesterol lowering agent
ATE236639T1 (de) * 1994-09-22 2003-04-15 Akzo Nobel Nv Verfahren zur herstellung von dosierungsformen durch feuchtgranulierung
TW592727B (en) * 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
JP4613275B2 (ja) 1998-11-02 2011-01-12 エラン ファーマ インターナショナル，リミティド 多粒子改質放出組成物
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
US20020054903A1 (en) * 1999-10-19 2002-05-09 Joseph Tyler Direct compression polymer tablet core
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
KR20130010512A (ko) 1999-10-29 2013-01-28 유로-셀티크 소시에떼 아노뉨 서방성 하이드로코돈 제형
KR100960200B1 (ko) 2000-10-30 2010-05-27 유로-셀티크 소시에떼 아노뉨 서방성 하이드로코돈 제형
CA2434835A1 (en) * 2001-02-13 2002-08-22 Astrazeneca Ab Novel modified released formulation
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US6982094B2 (en) 2001-09-28 2006-01-03 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US7323192B2 (en) * 2001-09-28 2008-01-29 Mcneil-Ppc, Inc. Immediate release tablet
US20040062804A1 (en) 2001-09-28 2004-04-01 Der-Yang Lee Modified release dosage forms
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
US7807197B2 (en) 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
EP1765307B1 (de) * 2004-05-24 2012-11-21 Mepha Schweiz AG Trockenbeschichtungsverfahren
CA2584547C (en) * 2004-10-19 2014-07-08 Miha Vrbinc Solid pharmaceutical composition comprising donepezil hydrochloride
US20060177415A1 (en) * 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
US8986669B2 (en) 2005-09-02 2015-03-24 Genzyme Corporation Method for removing phosphate and polymer used therefore
EP3000460A1 (en) 2005-09-15 2016-03-30 Genzyme Corporation Sachet formulation for amine polymers
DE102005060377A1 (de) * 2005-12-16 2007-06-21 Ratiopharm Gmbh Pharmazeutische Zusammensetzung enthaltend Donepezilhydrochlorid, Tablette hieraus und Verfahren zu deren Herstellung
WO2008018556A1 (en) 2006-08-09 2008-02-14 Mitsubishi Tanabe Pharma Corporation Tablet
JP2010504975A (ja) 2006-09-29 2010-02-18 ゲンズイメ コーポレーション アミドデンドリマー組成物
BRPI0720234A2 (pt) 2006-12-14 2013-12-24 Genzyme Corp Composição farmacêutica
CA2864738C (en) 2012-04-18 2017-07-18 Mallinckrodt Llc Immediate release, abuse deterrent pharmaceutical compositions
EP3064352B1 (en) 2013-10-25 2018-04-18 Kuraray Co., Ltd. Multilayer film and intermediate film for laminated glass formed of same
JP6850131B2 (ja) 2014-07-03 2021-03-31 スペックジーエックス エルエルシー 非セルロース多糖を含む、乱用抑止性即時放出製剤
CA3011595C (en) * 2016-02-09 2024-01-02 Albireo Ab Cholestyramine pellets and methods for preparation thereof
WO2017138877A1 (en) * 2016-02-09 2017-08-17 Albireo Ab Oral cholestyramine formulation and use thereof
US11478426B2 (en) 2018-09-25 2022-10-25 SpecGx LLC Abuse deterrent immediate release capsule dosage forms
CN114053234A (zh) * 2021-12-29 2022-02-18 江苏省药物研究所有限公司 一种阿卡波糖片及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB595444A (en) * 1945-07-09 1947-12-04 Gwilym Lloyd Thomas Improvements in or relating to medicaments, and to the preparation thereof
US3383237A (en) * 1964-01-29 1968-05-14 Richardson Merrell Inc Tablet coating
JPS56140915A (en) * 1980-04-07 1981-11-04 Yamanouchi Pharmaceut Co Ltd Pharmaceutical preparation for solid drug
US4895723A (en) * 1986-09-08 1990-01-23 Amer And Company Cholestyramine compositions and method for preparation thereof
ZA876640B (en) * 1986-09-26 1988-03-08 Warner-Lambert Company Treated lipid regulator
IT1200217B (it) * 1986-09-30 1989-01-05 Valducci Roberto Membrana per uso farmaceutico ed industriale

Also Published As

Publication number Publication date
IE900941L (en) 1990-09-16
KR0140211B1 (ko) 1998-06-01
PT93452B (pt) 1996-12-31
PT93452A (pt) 1990-11-07
BG91463A (bg) 1993-12-24
CS277488B6 (en) 1993-03-17
NO176043C (no) 1995-01-25
AU5136790A (en) 1990-09-20
US4956182A (en) 1990-09-11
HU901429D0 (en) 1990-06-28
CY1899A (en) 1990-03-15
OA09198A (fr) 1992-06-30
FI901241A0 (fi) 1990-03-13
GR3017460T3 (en) 1995-12-31
NO901183D0 (no) 1990-03-14
CN1047935C (zh) 2000-01-05
AU617601B2 (en) 1991-11-28
BG60501B1 (bg) 1995-06-30
FI92464C (fi) 1994-11-25
ATE128031T1 (de) 1995-10-15
CA2012300A1 (en) 1990-09-16
RO106953B1 (ro) 1993-08-30
ZA902001B (en) 1990-11-28
HU209958B (en) 1994-12-28
EG19669A (en) 1995-08-30
EP0387885B1 (en) 1995-09-20
JP2974719B2 (ja) 1999-11-10
CN1045921A (zh) 1990-10-10
KR900013946A (ko) 1990-10-22
DE69022452D1 (de) 1995-10-26
DD292837A5 (de) 1991-08-14
NO176043B (no) 1994-10-17
MY109744A (en) 1997-05-31
EP0387885A2 (en) 1990-09-19
PL163301B1 (en) 1994-03-31
ZW1890A1 (en) 1990-10-31
EP0387885A3 (en) 1992-06-17
RU2069558C1 (ru) 1996-11-27
HK51396A (en) 1996-03-29
YU52390A (en) 1991-10-31
DK0387885T3 (da) 1995-11-06
NZ232864A (en) 1992-04-28
IE70591B1 (en) 1996-12-11
DE69022452T2 (de) 1996-03-14
HUT54489A (en) 1991-03-28
AR246012A1 (es) 1994-03-30
IL93720A0 (en) 1990-12-23
NO901183L (no) 1990-09-17
FI92464B (fi) 1994-08-15
JPH03236326A (ja) 1991-10-22

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