|
DK0901786T3
(da)
*
|
1997-08-11 |
2007-10-08 |
Pfizer Prod Inc |
Faste farmaceutiske dispersioner med foröget biotilgængelighed
|
|
EP1741424B1
(en)
*
|
1997-08-11 |
2018-10-03 |
Pfizer Products Inc. |
Solid pharmaceutical dispersions with enhanced bioavailabilty
|
|
JPH11130698A
(ja)
*
|
1997-10-31 |
1999-05-18 |
Freunt Ind Co Ltd |
アルギン酸多価金属塩球状微粒子集合体、該球状微粒子集合体に難溶性薬剤を担持した放出制御製剤及びそれらの製造方法
|
|
IE980115A1
(en)
*
|
1998-02-16 |
2000-02-09 |
Biovail Internat Ltd |
Solubilizing delivery systems and method of manufacture
|
|
EP1970052A2
(en)
|
1999-02-09 |
2008-09-17 |
Pfizer Products Inc. |
Basic drug compositions with enhanced bioavailability
|
|
ATE404178T1
(de)
*
|
1999-02-10 |
2008-08-15 |
Pfizer Prod Inc |
Vorrichtung mit matrixgesteuerter wirkstofffreisetzung
|
|
BR0009176A
(pt)
|
1999-03-24 |
2001-12-18 |
Fmc Corp |
Partìcula granular, forma de dosagem, métodopara preparar uma partìcula granular, misturaseca, e, formulação granular
|
|
GB9920558D0
(en)
*
|
1999-08-31 |
1999-11-03 |
Bradford Particle Design Ltd |
Methods for particle formation and their products
|
|
DE60028754T2
(de)
|
1999-11-12 |
2007-05-31 |
Abbott Laboratories, Abbott Park |
Feste dispersion mit ritonavir, fenofibrat oder griseofulvin
|
|
US7364752B1
(en)
|
1999-11-12 |
2008-04-29 |
Abbott Laboratories |
Solid dispersion pharamaceutical formulations
|
|
MXPA02006324A
(es)
|
1999-12-23 |
2002-12-13 |
Pfizer Prod Inc |
Composiciones farmaceuticas que proporcionan concentraciones potenciadas de farmaco.
|
|
DE10013289A1
(de)
*
|
2000-03-17 |
2001-09-20 |
Knoll Ag |
Torasemid enthaltende pharmazeutische Zubereitungen
|
|
DE10026698A1
(de)
*
|
2000-05-30 |
2001-12-06 |
Basf Ag |
Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
|
|
US7115279B2
(en)
*
|
2000-08-03 |
2006-10-03 |
Curatolo William J |
Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors
|
|
US20030086972A1
(en)
*
|
2000-08-09 |
2003-05-08 |
Appel Leah E. |
Hydrogel-driven drug dosage form
|
|
EP1308156A4
(en)
*
|
2000-08-11 |
2009-07-15 |
Eisai R&D Man Co Ltd |
AGGREGATE SOLID DISPERSION WITH IMPROVED SOLUBILITY
|
|
KR20020014570A
(ko)
*
|
2000-08-18 |
2002-02-25 |
김충섭 |
고체분산화시킨 무정형 이프리플라본의 제조방법
|
|
WO2002024168A1
(fr)
*
|
2000-09-25 |
2002-03-28 |
Nippon Shinyaku Co., Ltd. |
Procede de production d'une dispersion solide medicinale
|
|
US6482847B2
(en)
*
|
2000-10-03 |
2002-11-19 |
Hoffmann-La Roche Inc. |
Amorphous form of cell cycle inhibitor having improved solubility and bioavailability
|
|
EP1340496A4
(en)
*
|
2000-11-07 |
2004-04-14 |
Hisamitsu Pharmaceutical Co |
PHARMACEUTICAL PREPARATION OF THE PERCUTANEOUS ABSORPTION TYPE
|
|
US6951656B2
(en)
|
2000-12-22 |
2005-10-04 |
Baxter International Inc. |
Microprecipitation method for preparing submicron suspensions
|
|
US8067032B2
(en)
|
2000-12-22 |
2011-11-29 |
Baxter International Inc. |
Method for preparing submicron particles of antineoplastic agents
|
|
US7037528B2
(en)
|
2000-12-22 |
2006-05-02 |
Baxter International Inc. |
Microprecipitation method for preparing submicron suspensions
|
|
US6884436B2
(en)
*
|
2000-12-22 |
2005-04-26 |
Baxter International Inc. |
Method for preparing submicron particle suspensions
|
|
US9700866B2
(en)
|
2000-12-22 |
2017-07-11 |
Baxter International Inc. |
Surfactant systems for delivery of organic compounds
|
|
US20050048126A1
(en)
|
2000-12-22 |
2005-03-03 |
Barrett Rabinow |
Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
|
|
US7193084B2
(en)
|
2000-12-22 |
2007-03-20 |
Baxter International Inc. |
Polymorphic form of itraconazole
|
|
US6977085B2
(en)
|
2000-12-22 |
2005-12-20 |
Baxter International Inc. |
Method for preparing submicron suspensions with polymorph control
|
|
WO2002083101A1
(de)
*
|
2001-04-11 |
2002-10-24 |
Bayer Aktiengesellschaft |
Nimodipin-tablette mit kontrollierter freisetzung und verfahren zu deren herstellung
|
|
MXPA03011784A
(es)
|
2001-06-22 |
2004-04-02 |
Pfizer Prod Inc |
Composiciones farmaceuticas de dispersiones de farmacos y polimeros neutros.
|
|
EP1269994A3
(en)
*
|
2001-06-22 |
2003-02-12 |
Pfizer Products Inc. |
Pharmaceutical compositions comprising drug and concentration-enhancing polymers
|
|
US20060003012A9
(en)
|
2001-09-26 |
2006-01-05 |
Sean Brynjelsen |
Preparation of submicron solid particle suspensions by sonication of multiphase systems
|
|
CN1558755A
(zh)
|
2001-09-26 |
2004-12-29 |
���ع��ʹ�˾ |
通过分散和除去溶剂或液相制备亚微米大小的纳米颗粒
|
|
US7112340B2
(en)
|
2001-10-19 |
2006-09-26 |
Baxter International Inc. |
Compositions of and method for preparing stable particles in a frozen aqueous matrix
|
|
ITMI20012749A1
(it)
*
|
2001-12-21 |
2003-06-21 |
Chiesi Farma Spa |
Procedimento per la preparazione mediante trattamento con microonde di composti di inclusione tra farmaco e ciclodestrine e prodotti ottenut
|
|
JP4508646B2
(ja)
*
|
2002-01-09 |
2010-07-21 |
エミスフェアー・テクノロジーズ・インク |
4−[(4−クロロ−2−ヒドロキシベンゾイル)アミノ]ブタン酸ナトリウムの多形体
|
|
CA2474838C
(en)
|
2002-02-01 |
2009-01-06 |
Pfizer Products Inc. |
Pharmaceutical compositions of amorphous dispersions of drugs and lipophilic microphase-forming materials
|
|
MY128945A
(en)
*
|
2002-04-16 |
2007-03-30 |
Kowa Co |
Solid dispersion composition
|
|
DE10224170A1
(de)
*
|
2002-05-31 |
2003-12-11 |
Desitin Arzneimittel Gmbh |
Pharmazeutische Zusammensetzung mit verzögerter Wirkstofffreisetzung
|
|
GB0216700D0
(en)
*
|
2002-07-18 |
2002-08-28 |
Astrazeneca Ab |
Process
|
|
US20040132771A1
(en)
*
|
2002-12-20 |
2004-07-08 |
Pfizer Inc |
Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors
|
|
ITMI20022748A1
(it)
|
2002-12-23 |
2004-06-24 |
Eurand Int |
Dispersioni solide stabilizzate di farmaco in un carrier organico e procedimento per la loro preparazione.
|
|
CA2532931A1
(en)
|
2003-08-04 |
2005-02-10 |
Pfizer Products Inc. |
Pharmaceutical compositions of adsorbates of amorphous drugs and lipophilic microphase-forming materials
|
|
US8377952B2
(en)
|
2003-08-28 |
2013-02-19 |
Abbott Laboratories |
Solid pharmaceutical dosage formulation
|
|
US8025899B2
(en)
|
2003-08-28 |
2011-09-27 |
Abbott Laboratories |
Solid pharmaceutical dosage form
|
|
DE602004031144D1
(de)
*
|
2003-11-14 |
2011-03-03 |
Ajinomoto Kk |
Feste dispersion oder medizinisches festes dispersionspräparat eines phenylalanin-derivats
|
|
US8535716B2
(en)
*
|
2004-04-01 |
2013-09-17 |
Tsrl, Inc. |
Methods and composition of extended delivery of water insoluble drugs
|
|
PE20060167A1
(es)
*
|
2004-04-08 |
2006-04-20 |
Wyeth Corp |
Formulaciones de dispersion solida que comprende acetato de bazedoxifeno
|
|
US7507823B2
(en)
|
2004-05-06 |
2009-03-24 |
Bristol-Myers Squibb Company |
Process of making aripiprazole particles
|
|
KR20120039763A
(ko)
*
|
2004-06-08 |
2012-04-25 |
버텍스 파마슈티칼스 인코포레이티드 |
약학 조성물
|
|
JP2006028130A
(ja)
*
|
2004-07-21 |
2006-02-02 |
Toa Eiyo Ltd |
ピモベンダン経口投与製剤
|
|
US7576216B2
(en)
|
2004-07-30 |
2009-08-18 |
Abbott Laboratories |
Preparation of pyridonecarboxylic acid antibacterials
|
|
FR2875409B1
(fr)
*
|
2004-09-17 |
2010-05-07 |
Sanofi Aventis |
Composition pharmaceutique comprenant une dispersion solide a matrice polymere comprenant une phase continue de polydextrose et une phase continue d'un polymere autre que du polydextrose
|
|
US20080095841A1
(en)
*
|
2004-10-06 |
2008-04-24 |
Eisai R&D Management Co., Ltd. |
Pharmaceutical Composition, Method for Producing the Same, and Method for Stabilizing Dihydropyridine Compound in the Pharmaceutical Composition
|
|
CA2593862C
(en)
*
|
2004-12-31 |
2014-10-21 |
Iceutica Pty Ltd |
Nanoparticle composition and methods for synthesis thereof
|
|
KR20070100820A
(ko)
|
2005-01-31 |
2007-10-11 |
가부시키가이샤 바이오세렌택 |
경피 흡수 제제, 경피 흡수 제제 유지 시트 및 경피 흡수제제 유지 용구
|
|
JP5284777B2
(ja)
*
|
2005-04-11 |
2013-09-11 |
アボット・ラボラトリーズ |
難溶性薬剤の改善された溶解プロファイルを有する医薬組成物
|
|
US9205046B2
(en)
*
|
2005-04-25 |
2015-12-08 |
The Governing Council Of The University Of Toronto |
Enhanced stability of inverse thermal gelling composite hydrogels
|
|
US9205047B2
(en)
*
|
2005-04-25 |
2015-12-08 |
The Governing Council Of The University Of Toronto |
Tunable sustained release of a sparingly soluble hydrophobic therapeutic agent from a hydrogel matrix
|
|
US20100016378A1
(en)
*
|
2005-04-28 |
2010-01-21 |
Toshio Suzuki |
Method of preventing dihydropyridine compound from degradation
|
|
EP1898920A1
(en)
*
|
2005-06-02 |
2008-03-19 |
Thallion Pharmaceuticals Inc. |
Formulation comprising farnesyl dibenzodiazepinone and a pharmaceutically acceptable surfactant
|
|
JP5243247B2
(ja)
*
|
2005-07-28 |
2013-07-24 |
アイエスピー インヴェストメンツ インコーポレイテッド |
スプレー乾燥された粉体及び粒状化された材料の特性の改良方法、並びにそれによって製造した製品
|
|
JP4974018B2
(ja)
*
|
2005-08-24 |
2012-07-11 |
オリンパステルモバイオマテリアル株式会社 |
生体材料とその製造方法
|
|
EP1926476B1
(en)
*
|
2005-08-29 |
2013-04-10 |
Sanofi-Aventis U.S. LLC |
Amorphous solid dispersions of 7-chloro-n,n,5-trimethyl-4-oxo-3-phenyl-3,5,-dihydro-4h-pyridazino[4,5-b]indole-1-acetamide
|
|
WO2007108463A1
(ja)
|
2006-03-23 |
2007-09-27 |
Shionogi & Co., Ltd. |
溶解性が改善された固形製剤
|
|
US20080085315A1
(en)
*
|
2006-10-10 |
2008-04-10 |
John Alfred Doney |
Amorphous ezetimibe and the production thereof
|
|
US20080152717A1
(en)
*
|
2006-12-14 |
2008-06-26 |
Isp Investments, Inc. |
Amorphous valsartan and the production thereof
|
|
US8613946B2
(en)
*
|
2006-12-21 |
2013-12-24 |
Isp Investment Inc. |
Carotenoids of enhanced bioavailability
|
|
WO2008092046A2
(en)
*
|
2007-01-26 |
2008-07-31 |
Isp Investments Inc. |
Amorphous oxcarbazepine and the production thereof
|
|
EP2125938A2
(en)
*
|
2007-01-26 |
2009-12-02 |
Isp Investments Inc. |
Formulation process method to produce spray dried products
|
|
KR20100016093A
(ko)
*
|
2007-03-30 |
2010-02-12 |
아지노모토 가부시키가이샤 |
고체 분산체 제제
|
|
US8703204B2
(en)
|
2007-05-03 |
2014-04-22 |
Bend Research, Inc. |
Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
|
|
US8309129B2
(en)
|
2007-05-03 |
2012-11-13 |
Bend Research, Inc. |
Nanoparticles comprising a drug, ethylcellulose, and a bile salt
|
|
US8426467B2
(en)
|
2007-05-22 |
2013-04-23 |
Baxter International Inc. |
Colored esmolol concentrate
|
|
US8722736B2
(en)
|
2007-05-22 |
2014-05-13 |
Baxter International Inc. |
Multi-dose concentrate esmolol with benzyl alcohol
|
|
WO2008149230A2
(en)
|
2007-06-04 |
2008-12-11 |
Pfizer Products Inc. |
Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate
|
|
US8974827B2
(en)
|
2007-06-04 |
2015-03-10 |
Bend Research, Inc. |
Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
|
|
WO2008152764A1
(ja)
|
2007-06-14 |
2008-12-18 |
Pola Pharma Inc. |
医薬組成物
|
|
EP2030613A1
(en)
|
2007-08-17 |
2009-03-04 |
Abbott GmbH & Co. KG |
Preparation of compositions with essentially noncrystalline embedded macrolide antibiotics
|
|
JPWO2009038112A1
(ja)
*
|
2007-09-21 |
2011-01-06 |
塩野義製薬株式会社 |
Npyy5受容体拮抗剤を含有する固形製剤
|
|
US9724362B2
(en)
|
2007-12-06 |
2017-08-08 |
Bend Research, Inc. |
Pharmaceutical compositions comprising nanoparticles and a resuspending material
|
|
US9233078B2
(en)
|
2007-12-06 |
2016-01-12 |
Bend Research, Inc. |
Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer
|
|
US20110065800A1
(en)
|
2008-05-14 |
2011-03-17 |
Haihong Fan |
Formulations for cathepsin k inhibitors
|
|
US20100160363A1
(en)
*
|
2008-12-19 |
2010-06-24 |
Aaipharma Services Corp. |
Extended-release pharmaceutical formulations
|
|
US20100159001A1
(en)
*
|
2008-12-19 |
2010-06-24 |
Cardinal John R |
Extended-Release Pharmaceutical Formulations
|
|
JPWO2010107040A1
(ja)
*
|
2009-03-19 |
2012-09-20 |
塩野義製薬株式会社 |
Npyy5受容体拮抗剤を含有する固形製剤
|
|
WO2010121328A1
(en)
|
2009-04-24 |
2010-10-28 |
Iceutica Pty Ltd |
A novel formulation of indomethacin
|
|
CN101618012B
(zh)
*
|
2009-07-10 |
2012-07-04 |
东华大学 |
一种难溶性药物固体分散体制备方法
|
|
FR2954771B1
(fr)
*
|
2010-04-23 |
2013-09-13 |
Mohamed Skiba |
Nouveau procede de synthese de copolymeres, terpolymeres et tetrapolymeres de cyclodextrines et leurs utilisations
|
|
CN103237458A
(zh)
*
|
2010-10-14 |
2013-08-07 |
雅培股份有限两合公司 |
类姜黄素固体分散体制剂
|
|
WO2013058751A1
(en)
*
|
2011-10-19 |
2013-04-25 |
Virginia Tech Intellectual Properties, Inc. |
Cellulose derivatives for enhancing bioavailability of flavonoids
|
|
JP5909796B2
(ja)
*
|
2012-03-02 |
2016-04-27 |
株式会社サンギ |
難溶性物質の水溶解性改善方法
|
|
JP2015522614A
(ja)
*
|
2012-07-23 |
2015-08-06 |
ダウ グローバル テクノロジーズ エルエルシー |
硬カプセルシェルのための皮膜組成物
|
|
KR101986683B1
(ko)
*
|
2012-12-13 |
2019-06-10 |
한미약품 주식회사 |
테트라졸 유도체를 활성 성분으로 포함하는 용해도가 개선된 고체 분산체
|
|
CN103191077B
(zh)
*
|
2013-04-18 |
2014-08-20 |
广东彼迪药业有限公司 |
一种格列齐特片及其制备方法
|
|
EP2832723B1
(en)
*
|
2013-07-29 |
2017-02-15 |
Zentiva, a.s. |
Stabilised amorphous forms of Saxagliptin
|
|
JP2015189677A
(ja)
*
|
2014-03-27 |
2015-11-02 |
テバ製薬株式会社 |
ソリフェナシン非晶質体を含有する医薬組成物
|
|
WO2015174475A1
(ja)
|
2014-05-15 |
2015-11-19 |
株式会社セラバリューズ |
経口摂取用組成物
|
|
US9526734B2
(en)
|
2014-06-09 |
2016-12-27 |
Iceutica Pty Ltd. |
Formulation of meloxicam
|
|
WO2016031651A1
(ja)
*
|
2014-08-29 |
2016-03-03 |
花王株式会社 |
難溶解性ポリフェノール類を含有する固体分散体の製造方法
|
|
EP3267977B1
(en)
*
|
2015-03-12 |
2021-08-11 |
DuPont Nutrition USA, Inc. |
Solid dispersions
|
|
AR105887A1
(es)
*
|
2015-09-04 |
2017-11-22 |
Sumitomo Chemical Co |
Composición, método de producción para la composición, y composición agroquímica
|
|
KR101912224B1
(ko)
*
|
2017-02-20 |
2018-10-26 |
충남대학교산학협력단 |
타다라필 함유 고체 분산체, 이를 포함하는 약제학적 조성물 및 이의 제조방법
|
|
WO2019172420A1
(ja)
*
|
2018-03-09 |
2019-09-12 |
協和発酵キリン株式会社 |
医薬組成物
|
|
CN111184692B
(zh)
*
|
2020-02-14 |
2021-10-26 |
南京大渊医美生物技术有限公司 |
一种白藜芦醇的制剂及其制备方法
|
|
CN111803447B
(zh)
*
|
2020-06-22 |
2022-08-09 |
三明学院 |
一种制备无定形药物的方法
|
|
WO2022090295A1
(en)
*
|
2020-10-28 |
2022-05-05 |
Merck Patent Gmbh |
Method for producing an amorphous solid dispersion and pharmaceutical composition for stabilizing active pharmaceutical ingredients
|
|
CN113350309B
(zh)
*
|
2021-08-09 |
2021-11-12 |
北京五和博澳药业股份有限公司 |
一种难溶性药物渗透泵控释片剂及其制备方法
|
|
CN117257964B
(zh)
*
|
2023-10-25 |
2024-04-02 |
苏州大学 |
基于碳酸氢铵的微波诱导吲哚美辛原位无定形化增溶技术
|
|
CN121044616A
(zh)
*
|
2025-11-05 |
2025-12-02 |
北京大学 |
一种氨基酸介导的非晶态稀土氧化物的合成方法
|