ATE255405T1 - Verfahren, um schwerlösliche arzneistoffe in einen amorphen zustand zu bringen - Google Patents

Verfahren, um schwerlösliche arzneistoffe in einen amorphen zustand zu bringen

Info

Publication number
ATE255405T1
ATE255405T1 AT96926600T AT96926600T ATE255405T1 AT E255405 T1 ATE255405 T1 AT E255405T1 AT 96926600 T AT96926600 T AT 96926600T AT 96926600 T AT96926600 T AT 96926600T AT E255405 T1 ATE255405 T1 AT E255405T1
Authority
AT
Austria
Prior art keywords
amorphous state
sparingly water
medical substance
soluble medical
amorphous
Prior art date
Application number
AT96926600T
Other languages
German (de)
English (en)
Inventor
Misao Nissan Chemical Miyamoto
Toshihisa Nissan Chemical Oda
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Application granted granted Critical
Publication of ATE255405T1 publication Critical patent/ATE255405T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Treatment Of Sludge (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT96926600T 1995-08-11 1996-08-08 Verfahren, um schwerlösliche arzneistoffe in einen amorphen zustand zu bringen ATE255405T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP20593695 1995-08-11
JP31040195 1995-11-29
JP31040095 1995-11-29
PCT/JP1996/002246 WO1997006781A1 (en) 1995-08-11 1996-08-08 Methods for making hardly soluble medicine amorphous

Publications (1)

Publication Number Publication Date
ATE255405T1 true ATE255405T1 (de) 2003-12-15

Family

ID=27328563

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96926600T ATE255405T1 (de) 1995-08-11 1996-08-08 Verfahren, um schwerlösliche arzneistoffe in einen amorphen zustand zu bringen

Country Status (14)

Country Link
US (1) US6462093B1 (enExample)
EP (2) EP0852140B1 (enExample)
KR (1) KR100498813B1 (enExample)
CN (1) CN1089232C (enExample)
AT (1) ATE255405T1 (enExample)
AU (1) AU702088B2 (enExample)
CA (1) CA2228907A1 (enExample)
CZ (1) CZ296072B6 (enExample)
DE (1) DE69630964T2 (enExample)
MX (1) MX9800717A (enExample)
NO (1) NO320486B1 (enExample)
NZ (1) NZ315089A (enExample)
TW (1) TW487582B (enExample)
WO (1) WO1997006781A1 (enExample)

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CA2228907A1 (en) 1997-02-27
CN1192677A (zh) 1998-09-09
EP1356807A3 (en) 2004-01-28
CZ32698A3 (cs) 1998-06-17
NO980549D0 (no) 1998-02-09
EP0852140B1 (en) 2003-12-03
EP1356807A2 (en) 2003-10-29
KR19990035836A (ko) 1999-05-25
NO980549L (no) 1998-04-02
AU6669396A (en) 1997-03-12
TW487582B (en) 2002-05-21
CN1089232C (zh) 2002-08-21
WO1997006781A1 (en) 1997-02-27
EP0852140A4 (enExample) 1998-07-29
JPWO9706781A1 (enExample) 1997-02-27
MX9800717A (es) 1998-11-30
US6462093B1 (en) 2002-10-08
EP0852140A1 (en) 1998-07-08
NO320486B1 (no) 2005-12-12
AU702088B2 (en) 1999-02-11
KR100498813B1 (ko) 2006-02-28
CZ296072B6 (cs) 2006-01-11
DE69630964T2 (de) 2004-10-28
DE69630964D1 (de) 2004-01-15
NZ315089A (en) 1999-06-29

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