CN105339026A - 注射装置 - Google Patents
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- A—HUMAN NECESSITIES
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- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/206—With automatic needle insertion
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- A—HUMAN NECESSITIES
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- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
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Abstract
本发明公开了一种注射装置，所述注射装置包括：致动器，所述致动器适于在被致动时引起注射序列的开始；锁定机构，所述锁定机构适于在锁定位置和解锁位置之间移动，在所述锁定位置，所述锁定机构防止所述致动器被致动，在所述解锁位置，所述致动器可被致动以引起所述注射序列的开始。所述锁定机构包括接触部分，所述接触部分在所述锁定机构的所述锁定位置抵靠所述致动器而伸出。所述接触部分包括弯曲表面。
Description
技术领域
本发明涉及一类注射装置，该类注射装置接收注射器，使注射器伸出，排出注射器的内容物，然后使注射器自动回缩。
背景技术
此前已知的注射装置在WO95/35126和EP-A-0516473中示出，并且趋于采用驱动弹簧和触发器，当可释放的锁定机构也接合时，该触发器在启用时造成驱动弹簧作用于注射器上。
从WO2007/036676已知一种自动注射器，该自动注射器具有锁定机构，在释放机构可被启用之前，该锁定机构必须被脱开。在其锁定位置，锁定机构也防止注射器抵靠返回弹簧的偏置而向前移动至注射装置之外，例如在夹持覆盖注射器针的罩的顶盖被移除时。在WO2007/036676中描述的注射装置中，锁定机构包括从注射装置的开口端突出的套管。套管被有回弹力的弹簧机构偏置至其伸出位置，该弹簧机构必须被克服以脱开锁定机构。锁定机构可通过例如将滑动套管向内移动至注射装置中(即，使套管回缩)而脱开。通过将滑动套管的端部抵靠组织施力，然后启用释放机构，可以做到这一点。
一般来讲，触发器可围绕轴线旋转，使得当它在第一端部处被压下时，第二端部(其通常接合驱动弹簧)也旋转，从而释放驱动弹簧，使注射器伸出，并且排出注射器的内容物。触发器包括突起，当可释放的锁定机构接合时，该突起可与可释放的锁定机构上的切口接合，从而允许启用触发器。当可释放的锁定机构不被接合时，突起邻接可释放的锁定机构的一部分，从而防止触发器的旋转和驱动弹簧的释放。这样，可以防止触发器的意外启用。
这种类型的注射装置的问题在于，当力被施加到触发器并且可释放的锁定机构不被接合时，触发器上的突起挠曲。施加到触发器的强力可造成突起中足够的挠曲，使得突起的端部能接合可释放的锁定机构上的切口，从而甚至在可释放的锁定机构未被接合时也允许启用触发器。
WO2006/106293公开了解决此问题的注射装置。在该案中，触发器包括其中具有切口的第一部分，第一部分在基本上平行于第一轴线的方向上从触发器的第一端部延伸。可释放的锁定机构包括沿着第二轴线的突起，以用于当可释放的锁定机构处于其第一位置时，与触发器的第一部分连通，并且用于当可释放的锁定机构处于其第二位置时，与切口连通。
据发现，当力在锁定机构处于其第一位置(即，接合)的情况下被施加到触发器时，触发器的第一部分和突起均挠曲，使得突起被迫远离切口，从而进一步减小触发器意外启用的风险。
然而，据发现，注射装置的使用者(诸如在WO2007/036676和WO2006/106293中描述的那些)很难正确地操作该装置。特别地，使用者很难在滑动套管已回缩时致动触发器，要么是因为滑动套管还没有很充分地回缩，要么是因为致动触发器所需的总力过大。由于这些部件的公差往往非常严格，滑动套管在可以触发之前必须被回缩的距离的误差边际常常非常小或为零。这对于使用者来说可能是非常令人沮丧的，因为他们可能要在启用注射装置时进行许多次不成功的尝试，原因是他们不知道滑动套管还没有完全回缩。此外，沮丧的使用者可能试图用力操作注射装置(即，通过将过大的压力施加到触发器)，并且因此损坏注射机构。
对上述问题的一个解决方案是，确保使用者知道滑动套管是否已完全回缩，使得他或她不会尝试过早地致动触发器。这样的解决方案是有益的，但使滑动套管完全回缩所需的力常常过大，否则就足以使套管回缩到特定的公差内。
因此，需要提供一种有利于装置的触发的注射装置。本发明解决了此类问题。
发明内容
本发明的注射装置设计用于解决该问题和其他问题。在第一方面，本发明提供了一种注射装置，该装置包括适于在被致动时引起注射序列的开始的致动器。注射装置还包括锁定机构，该锁定机构适于在锁定位置和解锁位置之间移动，在锁定位置，锁定机构防止致动器被致动，在解锁位置，致动器可被致动以引起注射序列的开始。锁定机构包括接触部分，该接触部分在锁定机构的锁定位置抵靠致动器而伸出。接触部分包括弯曲表面。
在本说明书中，术语“弯曲”是指任何倒圆的表面，其导致在接触部分和致动器之间的接触是基本上1维的线或点，而不是2维的表面。如果在所述部分和致动器之间的接触是1维的线或点，而不是2维的表面时，往往更容易确定接触部分脱离与致动器的接触。这也有利于制造过程，因为公差不需要那么准确。
在接触部分上提供弯曲表面减小了当锁定机构(例如，滑动套管)已回缩或几乎回缩时使致动器(例如，触发器)致动所需的总力，而不显著影响装置的安全性。还可以在力被施加在致动器上的同时使锁定机构回缩，这对于灵巧性降低的使用者来说常常是便利的。
此外，接触部分的弯曲表面可以帮助回缩锁定机构。弯曲表面可以例如相对于致动器布置，使得一旦锁定机构已充分地回缩(通过例如与使用者的皮肤接合)，在致动器上施加力的动作就会导致致动器使锁定机构进一步回缩，如下文进一步描述那样。
在某些实施例中，锁定机构被调适成当锁定机构处于其锁定位置时，接触部分不与致动器的接合表面接触。换句话讲，在某些实施例中，当锁定机构处于其锁定位置时，接触部分适于接触致动器的接合表面。接合表面可以是平坦表面，并且可以相对于注射装置的纵向轴线垂直，或相对于该轴线倾斜。倾角可以根据需要定制，以实现启用所述装置所需的必要的力。例如，该表面可以朝切口部分(上文提及)倾斜，以便增加成功接合的可能性；或者可以远离切口部分，以便减小意外接合的可能性。
锁定机构可以被调适成当锁定机构不处于其解锁位置时，接触部分的弯曲表面仅在接触部分的子部分上与接合表面接触。换句话讲，当锁定机构不处于其解锁位置时，接触部分的弯曲表面可以适于仅在接触部分的子部分上接触接合表面。子部分的大小可以根据启用所述装置所需的力来调整。
锁定机构可以被调适成当锁定机构处于其解锁位置时，接触位置不与致动器的接合表面接触。换句话讲，接触部分可以被调适成当锁定机构处于其解锁位置时，不接触致动器的接合表面。换句话讲，当锁定机构完全回缩时，接触表面可以完全脱离接合表面。
锁定机构优选地可在其锁定位置和其解锁位置之间移动，使得接触部分从其接触致动器的接合表面的位置移动至其不再接触致动器的接合表面的位置。
在优选布置中，锁定机构在其锁定位置和解锁位置之间沿着第一轴线A滑动。例如，锁定机构可以是能够在与使用者的皮肤接合时滑动的滑动套管。第一轴线A可以平行于注射装置的纵向轴线。
接触部分可包括从锁定机构延伸的第一凸起。优选地，第一凸起沿着第二轴线B延伸。
接合表面可以是在从致动器延伸的第一部分上的表面。优选地，第一凸起沿着第三轴线C延伸。
在特别优选的实施例中，第二轴线B和第三轴线C以在45和90度之间、60和90度之间、80和90度之间或90度的夹角彼此相交。此外，在另一优选实施例中，第一轴线A和第三轴线C彼此平行。在另一优选实施例中，第二轴线B与第一轴线A和第三轴线C两者都相交。上述轴线之间的关系可以彼此独立地提供。
致动器可被配置成在第一位置和第二位置之间移动，在第一位置，防止注射序列的开始；在第二位置，发生注射序列的开始。例如，注射装置还可包括驱动机构，其中致动器包括锁定表面，当致动器处于其第一位置时，锁定表面阻碍驱动机构；而当驱动机构处于其第二位置时，锁定表面不阻碍驱动机构。致动器和驱动机构之间的直接关系是便利和可靠的实现。
优选地，致动器在其第一和第二位置之间围绕枢轴旋转。这有利于致动器的致动，特别是对于灵巧性降低的人来说。在提供枢轴的情况下，特别优选的是，枢轴的轴线和第二轴线B以在45和90度之间、60和90度之间、80和90度之间或90度的夹角基本上彼此相交。
优选地，注射装置还包括注射器，该注射器可由驱动机构在注射序列开始时从注射器被完全容纳在注射装置的主体内的位置移动至注射器的针经由开口从注射装置的主体伸出的位置。驱动机构可以适于在注射器处于其伸出位置时经由针排出注射器的内容物。
在任何实施例中，注射装置可以包含选自由以下项组成的组的物质：戈利木单抗、激素、抗毒素、用于控制疼痛的物质、用于控制血栓形成的物质、用于控制或消除感染的物质、肽、蛋白、人胰岛素或人胰岛素类似物或衍生物、多糖、DNA、RNA、酶、抗体、寡核苷酸、抗过敏剂、抗组胺剂、抗炎剂、皮质类固醇、病情改善抗风湿药、红细胞生成素或疫苗，以用于治疗或预防类风湿性关节炎、银屑病性关节炎、强直性脊柱炎、溃疡性结肠炎、激素缺乏症、毒性、疼痛、血栓形成、感染、糖尿病、糖尿病性视网膜病、急性冠脉综合征、心绞痛、心肌梗死、动脉粥样硬化、癌症、黄斑变性、过敏、花粉症、发炎、贫血或脊髓发育不良或者用于表达保护性免疫。
所谓“注射装置可以包含物质”是指，该物质可以被包含在注射装置内的诸如小瓶或注射器的合适的药物容器内。这样的药物容器可以包含其他物质，诸如另外的活性或非活性成分。
在本发明的另一方面，提供了一种物质，该物质选自由以下项组成的组：戈利木单抗、激素、抗毒素、用于控制疼痛的物质、用于控制血栓形成的物质、用于控制或消除感染的物质、肽、蛋白、人胰岛素或人胰岛素类似物或衍生物、多糖、DNA、RNA、酶、抗体、寡核苷酸、抗过敏剂、抗组胺剂、抗炎剂、皮质类固醇、病情改善抗风湿药、红细胞生成素或疫苗，以用于通过使用根据上述实施例中的任一项的注射装置将所述物质递送至人类受治疗者而治疗或预防类风湿性关节炎、银屑病性关节炎、强直性脊柱炎、溃疡性结肠炎、激素缺乏症、毒性、疼痛、血栓形成、感染、糖尿病、糖尿病性视网膜病、急性冠脉综合征、心绞痛、心肌梗死、动脉粥样硬化、癌症、黄斑变性、过敏、花粉症、发炎、贫血或脊髓发育不良或者用于表达保护性免疫。
在本发明的又一方面，提供了一种注射装置，该注射装置用于通过使用该注射装置将以下物质递送至人类受治疗者而治疗或预防类风湿性关节炎、银屑病性关节炎、强直性脊柱炎、溃疡性结肠炎、激素缺乏症、毒性、疼痛、血栓形成、感染、糖尿病、糖尿病性视网膜病、急性冠脉综合征、心绞痛、心肌梗死、动脉粥样硬化、癌症、黄斑变性、过敏、花粉症、发炎、贫血或脊髓发育不良或者用于表达保护性免疫，所述物质选自由以下项组成的组：戈利木单抗、激素、抗毒素、用于控制疼痛的物质、用于控制血栓形成的物质、用于控制或消除感染的物质、肽、蛋白、人胰岛素或人胰岛素类似物或衍生物、多糖、DNA、RNA、酶、抗体、寡核苷酸、抗过敏剂、抗组胺剂、抗炎剂、皮质类固醇、病情改善抗风湿药、红细胞生成素或疫苗，其中注射装置是上述实施例中的任一项的注射装置。
所谓“递送物质”是指，注射装置用来例如通过皮下注射、真皮内注射或肌内注射将所述物质注射到人类受治疗者体内。所述物质可以结合诸如另外的活性或非活性成分的其他物质施用。
附图说明
现在将以举例方式结合附图描述本发明，在附图中：
图1示出了示例性的注射装置的透视图；
图2示出了图1的注射装置的侧视图，其中未示出注射装置的外壳的上部段；
图3示出了图2的注射装置的侧视图，其中未示出另外的部件；
图4示出了图2的注射装置的顶部平面图；
图5示出了示例性的触发器和可释放的锁定机构的透视图；
图6示出了图5的触发器和可释放的锁定机构的备选的透视图；
图7示出了图5的触发器和可释放的锁定机构的侧视图；以及
图8示出了根据本发明的触发器和可释放的锁定机构的侧视图。
具体实施方式
图1至4示出了示例性的注射装置110。注射装置110具有注射装置外壳112和纵向轴线101。
注射器122被容纳在外壳112中。注射装置110包括触发器114和可释放的锁定机构116。触发器114具有第一端部114a和第二端部114b。触发器114可围绕枢轴115从静止位置(如图2所示)旋转至活动位置。触发器114的第二端部114b与驱动联轴器121连接，驱动联轴器121由驱动弹簧120来作用。驱动联轴器121与注射器122连通。
触发器114围绕枢轴115在方向R上(即，在触发器114的第一端部114a处向下进入外壳112)的旋转造成触发器114的第二端部114b脱离驱动联轴器121，从而让驱动弹簧120沿着纵向轴线101且向外壳112中的孔118之外驱动注射器122(经由驱动联轴器121)。
可释放的锁定机构116与滑动套管126连通，滑动套管126在处于第一位置时从外壳112中的孔118突出。通过将滑动套管126沿着纵向轴线101移动至外壳112内而将锁定机构116停用到第二位置。
滑动套管126的第一端部126a可抵靠药物所递送进的身体放置，从而停用可释放的锁定机构116，并允许触发器114在方向R上从其静止位置旋转至其活动位置。
如从图5和6可见，触发器114在其第一端部114a设有具有切口152的第一部分150。第一部分150在基本上平行于纵向轴线101的方向上从触发器114a的第一端部114a延伸。
可释放的锁定机构116包括突起154，突起154在沿着垂直于纵向轴线101的垂直轴线181的方向上伸出。切口152的尺寸设计成接收突起154。
当可释放的锁定机构116处于其第一位置时，突起154的端部154a邻接第一部分150的下表面156，从而防止触发器114旋转。
当可释放的锁定机构116在滑动套管126移动至外壳112内之后处于其第二位置(未示出)时，切口152定位在突起154的端部上方，以允许切口在向下的力被施加到触发器112时越过突起154。因此，不再防止触发器112旋转，并且自身脱离驱动联轴器121，从而使注射器122伸出。
突起154包括第一脊160。触发器114包括第二部分162，第二部分162从触发器114的第一部分150延伸至切口152中，并且布置成在触发器114的旋转之后与第二部分162连通，使得第一脊160被锁定在第二部分162上，从而防止触发器114从其活动位置移动回其静止位置。
锁定机构116包括呈有回弹力的臂171的形式的偏置装置，臂171作用于外壳112的内表面，以在离开孔118的方向上偏置锁定机构116和滑动套管126。这样，在触发器112的启用之后，第一脊160被锁定在触发器112的第二部分162上，从而将触发器112保持在其活动位置。
触发器的第一部分150包括在第一部分150的下表面156上的第二脊164，第二脊定位在切口152和第一部分150的端部之间。当力在方向R上被施加到触发器114并且释放机构处于其第一(即，接合)位置时，第二脊164邻接突起154。这防止突起154移动至其端部154a移动经过第一部分150的端部的位置，否则，这将允许触发器114在可释放的锁定机构116仍被接合的同时旋转，从而意外“击发”注射装置110。
突起154具有倾斜表面166，斜表面166相对于第二轴线181成角度，当触发器114旋转并且可释放的锁定机构116脱开时，这允许触发器114的第二部分162更有效地越过突起154。
第一部分150离切口152成角度，使得当力被施加到触发器114并且锁定机构脱开时切口被偏转远离切口。
图4示出了两个轴线。轴线“A”平行于注射装置的纵向轴线，并且滑动套管126以上述方式沿着该轴线滑动。轴线“T”是触发器轴线，它是触发器114被配置成围绕其旋转的轴线。
图7更详细地示出了第一部分150、切口152和突起154。可以看出，突起仅包括平坦表面，即使如上所述倾斜且成角度。可以看出，第一部分150的远侧部分离切口152成角度。
图8示出了根据本发明的注射装置的第一部分850、切口852和突起854。在所有其他方面中，根据本发明的注射装置都与上文所述相同。突起854终止于接合第一部分850的弯曲表面853。由于突起在其接触致动器的地方是弯曲的，在突起854和致动器之间的接触为线(或在一些实施例中为点)，而不是表面。
弯曲表面基本上延伸经过接合第一部分850的突起854的端部的180°。然而，弯曲表面可以基本上延伸经过不同的角度，所述角度包括160°、140°、120°、90°、60°或40°。优选地，弯曲表面充分地延伸经过突起，以确保第一部分850的边缘仅在弯曲表面处接触突起。弯曲表面可以与突起854的中心成直线或偏移，这具体取决于优选实施。
如图所示，从致动器延伸的第一部分850相对于致动器且相对于轴线A为基本上平坦的。然而，第一部分850可以备选地如图7所示成角度，或者可以朝切口成角度，使得当锁定机构不正好处于解锁位置时启用所述装置所需的力减小。
轴线“B”在图8中示出。轴线B是突起854沿其从锁定机构延伸的轴线。轴线B相对于上述轴线A成大约90°的角度，但可以是在45和90度之间、60和90度之间、80和90度之间的其他角度，这具体取决于优选实施。
轴线“C”在图8中示出。轴线C是第一部分850沿其从致动器延伸的轴线。轴线C相对于上述轴线A大致平行，但可以是在0和45度之间、0和20度之间、0和10度之间、0和5度之间的其他角度，这具体取决于优选实施。此外，轴线C相对于上述轴线B成大约90°的角度，但可以是在45和90度之间、60和90度之间、80和90度之间的其他角度，这具体取决于优选实施。
应当理解，当锁定机构回缩(通过接合主体上的滑动套管)时，突起854的弯曲表面移动至更靠近致动器的第一部分850中的切口852。在该移动的某点处，在突起和致动器之间的接触的线(或在某些实施例中的点)到达切口开始处的边缘。这里，由于突起上的弯曲表面的布置，当突起在回缩的相同方向上进一步移动时，在致动器和锁定机构之间的法向力从基本上垂直于纵向轴线移动至至少部分地在回缩的方向上。因此，当力在突起处于该位置的情况下被施加到致动器上时，该力用来使锁定机构进一步回缩，并且有助于锁定机构移动至解锁位置。
在使用中，如上所述的注射装置可能用来递送诸如下列的物质：戈利木单抗、激素、抗毒素、用于控制疼痛的物质、用于控制血栓形成的物质、用于控制或消除感染的物质、肽、蛋白、人胰岛素或人胰岛素类似物或衍生物、多糖、DNA、RNA、酶、抗体、寡核苷酸、抗过敏剂、抗组胺剂、抗炎剂、皮质类固醇、病情改善抗风湿药、红细胞生成素或疫苗，以用于治疗或预防类风湿性关节炎、银屑病性关节炎、强直性脊柱炎、溃疡性结肠炎、激素缺乏症、毒性、疼痛、血栓形成、感染、糖尿病、糖尿病性视网膜病、急性冠脉综合征、心绞痛、心肌梗死、动脉粥样硬化、癌症、黄斑变性、过敏、花粉症、发炎、贫血或脊髓发育不良或者用于表达保护性免疫。除了这些物质之外，包含在注射装置内的任何药物也可包括技术人员了解的其他物质，诸如非活性成分。
当然，本领域的技术人员应当理解，特定的物质有效地用于治疗或预防特定的病症，如本领域所熟知的。例如，已知的是，抗过敏剂有效地用于治疗或预防过敏；抗组胺剂有效地用于治疗或预防花粉症；抗炎剂有效地用于治疗或预防发炎；等等。因此，可以设想出此处或权利要求书中列举的用于治疗或预防已知所述物质对其有功效的一种或多种病症的一种或多种物质的任何选择。
然而，在特定的例子中，已知戈利木单抗被有效地用于治疗或预防类风湿性关节炎、银屑病性关节炎、强直性脊柱炎或溃疡性结肠炎中的一者或多者或类风湿性关节炎、银屑病性关节炎、强直性脊柱炎和溃疡性结肠炎的任意组合或类风湿性关节炎、银屑病性关节炎、强直性脊柱炎和溃疡性结肠炎中的全部。
戈利木单抗可任选地结合诸如下列中的任一种或全部的一种或多种非活性成分使用：L-组氨酸、L-组氨酸单盐酸盐一水合物、山梨醇、聚山梨酸酯80和水。戈利木单抗可以存在于其中戈利木单抗是唯一的活性成分的组合物中。例如，戈利木单抗可以作为施用。
当然，应当理解，上文纯粹以举例方式描述了本发明，在本发明的范围内可以做出细节上的修改。
Claims (23)
1.一种注射装置，所述注射装置包括：
致动器，所述致动器适于在被致动时引起注射序列的开始；
锁定机构，所述锁定机构适于在锁定位置和解锁位置之间移动，在所述锁定位置，所述锁定机构防止所述致动器被致动，在所述解锁位置，所述致动器能够被致动以引起所述注射序列的开始，
其中所述锁定机构包括接触部分，所述接触部分在所述锁定机构的所述锁定位置抵靠所述致动器而伸出，其中所述接触部分包括弯曲表面。
2.根据权利要求1所述的注射装置，其中所述致动器包括接合表面。
3.根据权利要求2所述的注射装置，其中所述接合表面为平坦表面。
4.根据权利要求2或权利要求3所述的注射装置，其中所述锁定机构被调适成当所述锁定机构处于其锁定位置时，所述接触部分与所述致动器的所述接合表面接触。
5.根据权利要求2至4中的任一项所述的注射装置，其中所述锁定机构被调适成当所述锁定机构不处于其解锁位置时，所述接触部分的所述弯曲表面仅在所述接触部分的子部分上与所述接合表面接触。
6.根据权利要求2至5中的任一项所述的注射装置，其中所述锁定机构被调适成当所述锁定机构处于其解锁位置时，所述接触部分不与所述致动器的所述接合表面接触。
7.根据权利要求2至6中的任一项所述的注射装置，其中所述锁定机构能够在其锁定位置和其解锁位置之间移动，使得所述接触部分从其接触所述致动器的所述接合表面的位置移动至其不再接触所述致动器的所述接合表面的位置。
8.根据权利要求7所述的注射装置，其中所述锁定机构在其锁定位置和解锁位置之间沿着第一轴线A滑动。
9.根据权利要求2至8中的任一项所述的注射装置，其中所述接触部分包括从所述锁定机构延伸的突起。
10.根据权利要求9所述的注射装置，其中所述突起沿着第二轴线B延伸。
11.根据权利要求2至10中的任一项所述的注射装置，其中所述接合表面为在从所述致动器延伸的第一部分上的表面。
12.根据权利要求11所述的注射装置，其中所述第一部分沿着第三轴线C延伸。
13.根据从属于权利要求9的权利要求12所述的注射装置，其中所述第二轴线B和第三轴线C以在45和90度之间、60和90度之间、80和90度之间或90度的夹角彼此相交。
14.根据从属于权利要求7的权利要求13所述的注射装置，其中所述第一轴线A和第三轴线C彼此平行。
15.根据权利要求14所述的注射装置，其中所述第二轴线B与所述第一轴线A和所述第三轴线C两者都相交。
16.根据前述权利要求中的任一项所述的注射装置，其中所述致动器在第一位置和第二位置之间移动，在所述第一位置，防止所述注射序列的开始，在所述第二位置，发生所述注射序列的开始。
17.根据权利要求16所述的注射装置，所述注射装置还包括驱动机构，其中所述致动器包括锁定表面，当所述致动器处于其第一位置时，所述锁定表面阻碍所述驱动机构，而当所述驱动机构处于其第二位置时，所述锁定表面不阻碍所述驱动机构。
18.根据权利要求17所述的注射装置，其中所述致动器在其第一位置和第二位置之间围绕枢轴旋转。
19.根据从属于权利要求10的权利要求18所述的注射装置，其中所述枢轴的轴线和所述第二轴线B以在45和90度之间、60和90度之间、80和90度之间或90度的夹角基本上彼此相交。
20.根据从属于权利要求17的前述权利要求中的任一项所述的注射装置，所述注射装置还包括注射器，所述注射器能够由所述驱动机构在所述注射序列开始时从所述注射器被完全容纳在所述注射装置的主体内的位置移动至所述注射器的针经由开口从所述注射装置的所述主体伸出的位置，其中所述驱动机构适于在所述注射器处于其伸出位置时将所述注射器的内容物经由所述针排出。
21.根据前述权利要求中的任一项所述的注射装置，
所述注射装置包含选自由以下项组成的组的物质：戈利木单抗、激素、抗毒素、用于控制疼痛的物质、用于控制血栓形成的物质、用于控制或消除感染的物质、肽、蛋白、人胰岛素或人胰岛素类似物或衍生物、多糖、DNA、RNA、酶、抗体、寡核苷酸、抗过敏剂、抗组胺剂、抗炎剂、皮质类固醇、病情改善抗风湿药、红细胞生成素或疫苗，
以用于治疗或预防类风湿性关节炎、银屑病性关节炎、强直性脊柱炎、溃疡性结肠炎、激素缺乏症、毒性、疼痛、血栓形成、感染、糖尿病、糖尿病性视网膜病、急性冠脉综合征、心绞痛、心肌梗死、动脉粥样硬化、癌症、黄斑变性、过敏、花粉症、发炎、贫血或脊髓发育不良或者用于表达保护性免疫。
22.一种选自由以下项组成的组的物质：戈利木单抗、激素、抗毒素、用于控制疼痛的物质、用于控制血栓形成的物质、用于控制或消除感染的物质、肽、蛋白、人胰岛素或人胰岛素类似物或衍生物、多糖、DNA、RNA、酶、抗体、寡核苷酸、抗过敏剂、抗组胺剂、抗炎剂、皮质类固醇、病情改善抗风湿药、红细胞生成素或疫苗，
通过使用根据权利要求1至20中的任一项所述的注射装置将所述物质递送至人类受治疗者以用于治疗或预防类风湿性关节炎、银屑病性关节炎、强直性脊柱炎、溃疡性结肠炎、激素缺乏症、毒性、疼痛、血栓形成、感染、糖尿病、糖尿病性视网膜病、急性冠脉综合征、心绞痛、心肌梗死、动脉粥样硬化、癌症、黄斑变性、过敏、花粉症、发炎、贫血或脊髓发育不良或者用于表达保护性免疫。
23.一种注射装置，通过使用所述注射装置，其中所述注射装置是根据权利要求1至20中的任一项所述的注射装置，将以下物质递送至人类受治疗者以用于治疗或预防类风湿性关节炎、银屑病性关节炎、强直性脊柱炎、溃疡性结肠炎、激素缺乏症、毒性、疼痛、血栓形成、感染、糖尿病、糖尿病性视网膜病、急性冠脉综合征、心绞痛、心肌梗死、动脉粥样硬化、癌症、黄斑变性、过敏、花粉症、发炎、贫血或脊髓发育不良或者用于表达保护性免疫，
所述物质选自由以下项组成的组：戈利木单抗、激素、抗毒素、用于控制疼痛的物质、用于控制血栓形成的物质、用于控制或消除感染的物质、肽、蛋白、人胰岛素或人胰岛素类似物或衍生物、多糖、DNA、RNA、酶、抗体、寡核苷酸、抗过敏剂、抗组胺剂、抗炎剂、皮质类固醇、病情改善抗风湿药、红细胞生成素或疫苗。
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| WO (1) | WO2014198799A1 (zh) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110139685A (zh) * | 2016-08-26 | 2019-08-16 | 赛诺菲-安万特德国有限公司 | 用于附接到注射装置的装置 |
| CN117442814A (zh) * | 2023-07-19 | 2024-01-26 | 艾可泰科生物科技(浙江)有限公司 | 一种促进糖尿病溃疡创面愈合的干细胞局部注射装置 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USD830538S1 (en) * | 2016-05-04 | 2018-10-09 | Nuance Designs Of Ct, Llc | Autoinjector |
| USD831822S1 (en) * | 2016-05-17 | 2018-10-23 | Nuance Designs Of Ct, Llc | Autoinjector |
| USD890332S1 (en) | 2018-02-08 | 2020-07-14 | Nuance Designs Of Ct, Llc | Autoinjector |
| JP7194756B2 (ja) | 2018-06-08 | 2022-12-22 | アンタレス・ファーマ・インコーポレーテッド | 自動挿入注射器 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030229308A1 (en) * | 2002-06-05 | 2003-12-11 | Israil Tsals | Injector adapter and combination thereof |
| WO2006106293A1 (en) * | 2005-04-06 | 2006-10-12 | Cilag Gmbh International | Injection device (modified trigger) |
| CN1893992A (zh) * | 2003-12-18 | 2007-01-10 | 诺沃挪第克公司 | 具有皮肤拉紧装置的喷嘴设备 |
| CN101541362A (zh) * | 2006-11-13 | 2009-09-23 | 西拉格国际有限公司 | 注射装置 |
Family Cites Families (627)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE229932C (zh) | ||||
| DE356704C (de) | 1918-03-15 | 1922-07-27 | Edmondo Luswergh Dr | Spritze |
| DE387465C (de) | 1923-03-21 | 1924-01-03 | Agostino G Rossi Dr | Kolbenspritze |
| US1845036A (en) | 1930-03-12 | 1932-02-16 | Herbert H Busher | Hypodermic syringe |
| GB412054A (en) | 1932-08-04 | 1934-06-21 | Loewe Opta Gmbh | Improvements in wireless receivers |
| US2019382A (en) | 1935-02-19 | 1935-10-29 | Art Metal Works Inc | Torch |
| US2147616A (en) | 1937-07-09 | 1939-02-14 | Elmer J Chaput | Dental and medical hypodermic syringe |
| US2295849A (en) | 1940-10-25 | 1942-09-15 | Gustave L Kayden | Attachment for hypodermic syringes |
| US2531267A (en) | 1947-10-16 | 1950-11-21 | Harnisch Fritz | Hypodermic syringe operating device |
| FR1078911A (fr) | 1949-08-17 | 1954-11-24 | Seringue hypodermique automatique et son ampoule | |
| FR1014881A (fr) | 1950-03-21 | 1952-08-25 | Appareil automatique pour injections parentérales | |
| US2764977A (en) | 1951-05-24 | 1956-10-02 | Becton Dickinson Co | Hypodermic injection mechanism |
| US2854975A (en) | 1952-08-07 | 1958-10-07 | Miljam Instr Corp | Hypodermic syringe |
| US2845065A (en) | 1954-02-05 | 1958-07-29 | Gabriel Daniel | Deception element for hypodermic syringes |
| FR1169935A (fr) | 1957-03-22 | 1959-01-07 | S E D A T Soc D Etudes Et D Ap | Perfectionnements apportés aux ampoules auto-injectables |
| US2828742A (en) | 1957-05-02 | 1958-04-01 | American Home Prod | Cartridge-needle unit |
| GB909898A (en) | 1958-04-17 | 1962-11-07 | Donald Travers Lewis | Improvements in or relating to a device for automatically effecting injections with a hypodermic syringe |
| US3076455A (en) | 1958-12-19 | 1963-02-05 | Robert K Mcconnaughey | Holder for hypodermic syringe cartridges |
| GB964585A (zh) | 1960-03-23 | |||
| US3329146A (en) | 1963-10-02 | 1967-07-04 | Baxter Laboratories Inc | Needle container |
| US3320955A (en) | 1963-10-09 | 1967-05-23 | Sarnoff Stanley Jay | Automatic injection hypodermic syringe |
| FR1538565A (fr) | 1967-07-26 | 1968-09-06 | Seringue hypodermique automatique | |
| US3543603A (en) | 1968-01-10 | 1970-12-01 | Rex Chainbelt Inc | Automatic quick release mechanism |
| NO124977B (zh) | 1968-08-09 | 1972-07-03 | Philips Nv | |
| FR2040830A5 (zh) | 1969-04-15 | 1971-01-22 | Ben Moura Pierre | |
| BE755224A (fr) | 1969-08-25 | 1971-02-24 | Philips Nv | Seringue d'injection |
| DE6944378U (de) | 1969-11-14 | 1970-04-16 | Georg A Henke Gmbh Fa | Selbsttaetiges injektionsgeraet |
| US3674033A (en) | 1970-08-13 | 1972-07-04 | John Powers | Drainage system for body cavities |
| US3702608A (en) | 1970-12-15 | 1972-11-14 | Robert C Tibbs | Painless injection device with powered plunger |
| BE795162A (fr) | 1972-02-10 | 1973-08-08 | Philips Nv | Injektie-inrichting |
| JPS4921036A (zh) | 1972-06-16 | 1974-02-25 | ||
| US3797488A (en) | 1972-07-10 | 1974-03-19 | Ampoules Inc | Ampoule applicator with one-way clutch |
| JPS4977487A (zh) | 1972-11-29 | 1974-07-25 | ||
| US3880163A (en) | 1973-10-26 | 1975-04-29 | Jack H Ritterskamp | Medicinal syringe actuating device |
| NL172403C (nl) | 1974-04-08 | 1983-09-01 | Duphar Int Res | Injectiespuit met een patroon en een patroonhouder, waarbij de patroonhouder voorzien is van vergrendelingsmiddelen voor de patroon, alsmede patroonhouder voor een injectiespuit. |
| GB1514725A (en) | 1975-05-23 | 1978-06-21 | Everett Med Prod Ltd | Hyperdermic needle assembly |
| GB1583157A (en) | 1976-05-07 | 1981-01-21 | Kenova Ab | Syringes |
| US4165739A (en) | 1976-09-02 | 1979-08-28 | Doherty Norman R | Inoculator |
| US4180070A (en) | 1977-08-29 | 1979-12-25 | Abbott Laboratories | Disposable double vial syringe |
| US4222380A (en) | 1977-12-02 | 1980-09-16 | Olympus Optical Co., Ltd. | Celiac injector |
| JPS5487694A (en) | 1977-12-23 | 1979-07-12 | Kankiyou Kagaku Kenkiyuushiyo | Granular active carbon and its manufacture |
| DE2812729A1 (de) | 1978-03-23 | 1979-09-27 | Michael Becker | Injektionsvorrichtung zur intramuskulaeren einspritzung, vornehmlich von insulin |
| US4185628A (en) | 1978-05-31 | 1980-01-29 | Kopfer Rudolph J | Compartmental syringe |
| US4194505A (en) | 1978-09-15 | 1980-03-25 | Vac-O-Cast, Inc. | Containerized hypodermic module |
| DE2929425A1 (de) | 1979-07-20 | 1981-02-12 | Lothar Kling | Vorrichtung fuer injektionsspritzen zur intramuskulaeren und subentanen injektion |
| US4237882A (en) | 1979-09-27 | 1980-12-09 | Sherwood Medical Industries Inc. | Needle sheath |
| DE8006721U1 (de) | 1980-03-12 | 1981-09-03 | Becker, Michael, 5020 Frechen | Injektionsvorrichtung zur intramuskulaeren einspritzung eines medikamentes, insbesondere von insulin |
| US4299238A (en) | 1980-06-24 | 1981-11-10 | Baidwan Balinderjeet S | Vented piston and push-rod subassembly for use in a syringe barrel |
| GB2080689B (en) | 1980-07-29 | 1984-10-31 | Dent Hugh Robert | Sterilising fitments for injection devices |
| FR2506161A1 (fr) | 1981-05-20 | 1982-11-26 | Alsetex Armement | Seringue auto-injectante |
| US4403989A (en) | 1981-09-14 | 1983-09-13 | Syntex (U.S.A.) Inc. | Injection device |
| US4407283A (en) | 1981-10-19 | 1983-10-04 | Dale C. Grier | Self-injecting syringe |
| US4394863A (en) | 1981-10-23 | 1983-07-26 | Survival Technology, Inc. | Automatic injector with cartridge having separate sequentially injectable medicaments |
| US4378015A (en) | 1981-12-21 | 1983-03-29 | Wardlaw Stephen C | Automatic injecting syringe |
| US4425120A (en) | 1982-04-15 | 1984-01-10 | Sampson Norma A | Shielded hypodermic syringe |
| US4430080A (en) | 1982-06-09 | 1984-02-07 | Becton, Dickinson And Company | Syringe assembly with snap-fit components |
| US4430082A (en) | 1982-06-25 | 1984-02-07 | Hoffmann-La Roche Inc. | Hypodermic syringe assembly |
| US4500310A (en) | 1982-12-20 | 1985-02-19 | Becton, Dickinson And Company | Variable sealing pressure plunger rod assembly |
| US4676530A (en) | 1983-04-07 | 1987-06-30 | Warner-Lambert Company | Coupling assembly for use in fluid flow systems |
| US4521237A (en) | 1983-05-23 | 1985-06-04 | Kahle Engineering Co. | Glass dose syringe |
| US4561856A (en) | 1983-08-18 | 1985-12-31 | Cochran Ulrich D | Infusion pump |
| DE3342407A1 (de) | 1983-11-24 | 1985-06-05 | Erwin 6950 Mosbach Maurer | Injektionsgeraet |
| NZ212899A (en) | 1984-07-31 | 1987-10-30 | Phillips Pty Ltd N J | Piston operated adjustable volume dose injector for animals |
| AU573369B2 (en) | 1984-07-31 | 1988-06-02 | N.J. Phillips Pty. Limited | A rumen injector |
| DD234613A1 (de) | 1985-02-14 | 1986-04-09 | Karl Marx Stadt Tech Hochschul | Vorrichtung mit tagesmedikamentdepot zur schmerzarmen injektion |
| US4627835A (en) | 1985-03-11 | 1986-12-09 | Strato Medical Corporation | Tubing assembly for infusion device |
| US4636201A (en) | 1985-11-01 | 1987-01-13 | American Hospital Supply Corporation | Hypodermic syringe having a protective sheath cover |
| US4636198A (en) | 1985-11-18 | 1987-01-13 | Mallinckrodt, Inc. | Power syringe with volume reducing adapter |
| US4695274A (en) | 1986-01-31 | 1987-09-22 | Fox Richard L | Protected hypodermic needle |
| US4639250A (en) | 1986-02-20 | 1987-01-27 | Becton, Dickinson And Company | Syringe barrel and hypodermic needle assembly |
| US4735311A (en) | 1986-04-09 | 1988-04-05 | The West Company | Needle shield assembly |
| US4744786A (en) | 1986-06-17 | 1988-05-17 | Cordis Corporation | Infusion pump |
| FR2600258A1 (fr) | 1986-06-18 | 1987-12-24 | Hazon Bernard | Dispositif pousse-seringue pour injections parenterales automatiques a asservissement et programmation |
| DE3638984C3 (de) | 1986-11-14 | 1993-11-18 | Haselmeier Wilhelm Fa | Injektionsgerät |
| CA1285441C (en) | 1987-03-17 | 1991-07-02 | Roy D. Mcnaughton | Mcnaughton syringe shield type b |
| DE3715258C2 (de) | 1987-05-08 | 1996-10-31 | Haselmeier Wilhelm Fa | Injektionsgerät |
| FR2629706B1 (fr) | 1988-04-11 | 1992-05-22 | Accaries Claude | Appareil d'injection de liquide, notamment a usage de soins dentaires |
| WO1988010129A1 (en) | 1987-06-25 | 1988-12-29 | Nova Medical Pty. Limited | Slow delivery injection device |
| US5364369A (en) | 1987-07-08 | 1994-11-15 | Reynolds David L | Syringe |
| US4874384A (en) | 1987-07-13 | 1989-10-17 | International Medical Innovators, Inc. | Needle safety guard |
| US4787891A (en) | 1987-07-13 | 1988-11-29 | Paul Levin | Syringe holder and applicator |
| AU3071689A (en) | 1988-03-01 | 1989-09-07 | Ryan Medical, Inc. | Safety needled medical devices capable of one-handed manipulation |
| JPH0534669Y2 (zh) | 1988-03-16 | 1993-09-02 | ||
| GB8809115D0 (en) | 1988-04-18 | 1988-05-18 | Turner R C | Syringes |
| US5156599A (en) | 1988-06-28 | 1992-10-20 | Sherwood Medical Company | Syringe and sliding locking needle shield |
| US5026349A (en) | 1988-10-05 | 1991-06-25 | Autoject Systems Inc. | Liquid medicament injector system |
| FR2638359A1 (fr) | 1988-11-03 | 1990-05-04 | Tino Dalto | Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau |
| US5263933A (en) | 1988-12-14 | 1993-11-23 | Patco Ventures Ltd. | Safety syringe needle device with interchangeable and retractable needle platform |
| JPH02185261A (ja) | 1988-12-20 | 1990-07-19 | Candera Estourci Miracle | 注射器 |
| US4988339A (en) | 1988-12-30 | 1991-01-29 | Vadher Dinesh L | Retractable needle/syringe devices for blood collection, catheterization, and medicinal injection procedures |
| US4929232A (en) | 1989-03-30 | 1990-05-29 | Becton, Dickinson And Company | Syringe having tamper evidence features |
| JPH02299660A (ja) | 1989-05-15 | 1990-12-11 | Yokoshima Rika Sangyo Kk | 容器兼用注射器への薬液充填方法 |
| US4969870A (en) | 1989-06-07 | 1990-11-13 | The Regents Of The University Of California | Method and apparatus for intraosseous infusions |
| US6096005A (en) | 1989-07-11 | 2000-08-01 | Mdc Investment Holdings, Inc. | Retractable needle medical devices |
| US4994034A (en) | 1989-07-11 | 1991-02-19 | Botich Michael J | Retractable needle hypodermic syringe system |
| DE3929777A1 (de) | 1989-09-07 | 1991-03-14 | Dieter Dr Lucas | Injektionsspritze |
| JPH03129156A (ja) | 1989-10-14 | 1991-06-03 | Shigeru Hayashi | 摩擦車駆動機構 |
| US5112119A (en) | 1989-10-27 | 1992-05-12 | International Business Machines Corp. | Support structure for devices in a computer apparatus |
| US5312335A (en) | 1989-11-09 | 1994-05-17 | Bioject Inc. | Needleless hypodermic injection device |
| GB8926825D0 (en) | 1989-11-28 | 1990-01-17 | Glaxo Group Ltd | Device |
| CN2059579U (zh) | 1989-12-22 | 1990-07-25 | 国营建安机械厂 | 兽用静脉进针器 |
| BR9106040A (pt) | 1990-02-12 | 1993-01-05 | Procter & Gamble | Processo para reduzir o odor associado com fluidos corporeos,artigo de manufatura e fralda,absorvente higienico ou revestimento de calcinhas |
| US5057079A (en) | 1990-04-03 | 1991-10-15 | Roland Tiemann | Sheathing device for after use protection from a syringe needle |
| US5624400A (en) | 1990-05-09 | 1997-04-29 | Safety Syringes, Inc. | Disposable self-shielding aspirating syringe |
| JP3320412B2 (ja) | 1990-07-04 | 2002-09-03 | イーストランド テクノロジー オーストラリア ピーティーワイ エルティーディー | 改良型非経口投与装置 |
| FR2665079A1 (fr) | 1990-07-27 | 1992-01-31 | Conception Fabr Innovations Me | Seringue a aiguille jetable. |
| US5073170A (en) | 1990-08-09 | 1991-12-17 | Hollister Incorporated | Drainage tube retention device |
| GB9100819D0 (en) | 1991-01-15 | 1991-02-27 | Medimech Int Ltd | Subcutaneous injector |
| US5098400A (en) | 1991-02-14 | 1992-03-24 | Sherwood Medical Company | Needle shield |
| US5188613A (en) | 1991-04-03 | 1993-02-23 | Shaw Thomas J | Nonreusable syringe with safety indicator |
| US5271744A (en) | 1991-04-29 | 1993-12-21 | George C. Kramer | System and method for rapid vascular drug delivery |
| US5868711A (en) | 1991-04-29 | 1999-02-09 | Board Of Regents, The University Of Texas System | Implantable intraosseous device for rapid vascular access |
| US5451210A (en) | 1991-04-29 | 1995-09-19 | Lifequest Medical, Inc. | System and method for rapid vascular drug delivery |
| US5405362A (en) | 1991-04-29 | 1995-04-11 | The Board Of Regents For The University Of Texas System | Interactive external defibrillation and drug injection system |
| US5176643A (en) | 1991-04-29 | 1993-01-05 | George C. Kramer | System and method for rapid vascular drug delivery |
| US5147325A (en) | 1991-05-03 | 1992-09-15 | Sherwood Medical Company | Rigid needle shield |
| GB9111600D0 (en) | 1991-05-30 | 1991-07-24 | Owen Mumford Ltd | Improvements relating to injection devices |
| EP0518416A1 (en) | 1991-06-13 | 1992-12-16 | Duphar International Research B.V | Injection device |
| GB9115765D0 (en) | 1991-07-22 | 1991-09-04 | Britt Adrian J | Bacterial enzyme for cocaine detection |
| EP0525525B1 (de) | 1991-07-24 | 1995-05-03 | Medico Development Investment Company | Injektor |
| EP0612227B1 (en) | 1991-11-12 | 1999-05-12 | RAMEL, Urs. A | Lancet device |
| US5242400A (en) | 1991-12-06 | 1993-09-07 | The Medtech Group, Inc. | Disposable pre-filled syringe with retractable needle |
| GB9200219D0 (en) | 1992-01-07 | 1992-02-26 | Medimech Int Ltd | Automatic injectors |
| US5242416A (en) | 1992-01-09 | 1993-09-07 | Hutson Clifford L | Shield assembly for needle syringes |
| EP0562671B1 (en) | 1992-03-27 | 1996-05-29 | Duphar International Research B.V | Automatic injector |
| ZA932947B (en) | 1992-04-28 | 1993-10-27 | Schering Plough Healthcare | Applicator for semisolid medications |
| US6290683B1 (en) | 1992-04-29 | 2001-09-18 | Mali-Tech Ltd. | Skin piercing needle assembly |
| IL105706A (en) | 1992-05-15 | 1996-10-16 | Safe T Ltd | Dispensing device for hollow needles |
| US5250026A (en) | 1992-05-27 | 1993-10-05 | Destron/Idi, Inc. | Adjustable precision transponder injector |
| US5267962A (en) | 1992-06-10 | 1993-12-07 | Jenson Robert W | Disposable hypodermic syringe with needle safe feature |
| EP0585626A1 (de) | 1992-08-14 | 1994-03-09 | Hoechst Aktiengesellschaft | Kaschierte Mineralfasermatte |
| WO1994004207A1 (en) | 1992-08-17 | 1994-03-03 | Allard Edward F | Method and apparatus for a retracting needle |
| US5267963A (en) | 1992-08-21 | 1993-12-07 | Nicholas Bachynsky | Medication injection device |
| WO1994005200A1 (en) | 1992-09-01 | 1994-03-17 | Adair Edwin Lloyd | Sterilizable endoscope with separable disposable tube assembly |
| US5190526A (en) | 1992-09-18 | 1993-03-02 | Murray Kenneth W | Hypodermic safety syringe with retracting needle system |
| AU5293393A (en) | 1992-09-28 | 1994-04-26 | Equidyne Systems, Incorporated | Hypodermic jet injector |
| US5569189A (en) | 1992-09-28 | 1996-10-29 | Equidyne Systems, Inc. | hypodermic jet injector |
| DE69319753T2 (de) | 1992-11-19 | 1999-04-15 | Galli Rosaria & C | Automatische injektionsvorrichtung für vorgefüllte spritzen |
| US5320609A (en) | 1992-12-07 | 1994-06-14 | Habley Medical Technology Corporation | Automatic pharmaceutical dispensing syringe |
| IT1256577B (it) | 1992-12-11 | 1995-12-11 | Ermanno Greco | Dispositivo predisposto per la somministrazione automatica di un farmaco per via intradermica. |
| US5370621A (en) | 1992-12-14 | 1994-12-06 | Mallinckrodt Medical, Inc. | Insert device for facilitating limited aspiration of a delivery apparatus |
| US5569191A (en) | 1992-12-15 | 1996-10-29 | Meyer; Gabriel | Device for preparing a medicinal substance solution, suspension or emulsion |
| US5250037A (en) | 1992-12-18 | 1993-10-05 | Becton, Dickinson And Company | Syringe having needle isolation features |
| DE69427226T2 (de) | 1993-03-24 | 2001-08-30 | Owen Mumford Ltd | Vorrichtung zur injektion |
| US5540666A (en) | 1993-03-31 | 1996-07-30 | Immuno Aktiengesellschaft | Cannula shield and injection syringe system |
| US5330081A (en) | 1993-04-08 | 1994-07-19 | Impact Products, Inc. | Measuring dosage dispenser |
| JP3296025B2 (ja) | 1993-05-21 | 2002-06-24 | ニプロ株式会社 | 薬液充填式注射器 |
| US5368577A (en) | 1993-05-24 | 1994-11-29 | Biocon International Corporation | Needle stick prevention device |
| US5540664A (en) | 1993-05-27 | 1996-07-30 | Washington Biotech Corporation | Reloadable automatic or manual emergency injection system |
| US5358489A (en) | 1993-05-27 | 1994-10-25 | Washington Biotech Corporation | Reloadable automatic or manual emergency injection system |
| WO1995031235A1 (en) | 1994-05-16 | 1995-11-23 | Washington Biotech Corporation | Modular automatic or manual emergency medicine injection system |
| DE69426390T2 (de) | 1993-07-31 | 2001-04-12 | Weston Medical Ltd | Nadelloser injektor |
| US5425715A (en) | 1993-08-05 | 1995-06-20 | Survival Technology, Inc. | Reloadable injector |
| US5312364A (en) | 1993-08-06 | 1994-05-17 | Pyng | Intraosseous infusion device |
| JP3199524B2 (ja) | 1993-08-06 | 2001-08-20 | 日本メジフィジックス株式会社 | ルアーニードルユニット及び注射器 |
| FR2717086A1 (fr) | 1994-03-11 | 1995-09-15 | Debiotech | Dispositif de seringue pour le mélange de deux composés. |
| US5827262A (en) | 1993-09-07 | 1998-10-27 | Debiotech S.A. | Syringe device for mixing two compounds |
| US5385551A (en) | 1993-09-22 | 1995-01-31 | Shaw; Thomas J. | Nonreusable medical device with front retraction |
| US5372586A (en) | 1993-10-20 | 1994-12-13 | Habley Medical Technology Corp. | Telescoping pharmaceutical storage and mixing syringe |
| JPH07120326A (ja) | 1993-10-22 | 1995-05-12 | Komatsu Ltd | 波長検出装置 |
| JPH07116224A (ja) | 1993-10-28 | 1995-05-09 | Arute:Kk | 注射器 |
| CA2135706C (en) | 1993-11-15 | 1999-06-15 | Walter E. Cover | Retractable-needle cannula insertion set with refinements to better control leakage, retraction speed, and reuse |
| US5330430A (en) | 1993-12-06 | 1994-07-19 | Sullivan Robert J | Retractable syringe applicator |
| US5356395A (en) | 1993-12-14 | 1994-10-18 | Chen Shih Shuan | Safety syringe shield |
| FR2715071B1 (fr) | 1994-01-17 | 1996-03-01 | Aguettant Lab | Injecteur automatique de médicament. |
| JPH07213610A (ja) | 1994-01-28 | 1995-08-15 | Shirota Denki Rozai Kk | 歯科用の電動注射器 |
| US5478316A (en) | 1994-02-02 | 1995-12-26 | Becton, Dickinson And Company | Automatic self-injection device |
| US5514097A (en) | 1994-02-14 | 1996-05-07 | Genentech, Inc. | Self administered injection pen apparatus and method |
| WO1995024176A1 (en) | 1994-03-07 | 1995-09-14 | Bioject, Inc. | Ampule filling device |
| FR2718357B1 (fr) | 1994-04-06 | 1997-10-03 | Defarges Alain Moreau | Perfectionnements apportés à un dispositif d'injection par jet sans aiguille. |
| GB9408500D0 (en) | 1994-04-28 | 1994-06-22 | Pa Consulting Services | Improvements in or relating to injection devices |
| US5411488A (en) | 1994-05-06 | 1995-05-02 | Sterling Winthrop Inc. | Pre-filled syringe and pre-filled cartridge having an improved plunger and plunger rod for reducing syringing force |
| US5609584A (en) | 1994-05-18 | 1997-03-11 | Gettig Technologies, Inc. | Adaptor system for use with a syringe |
| EP1228777B1 (de) | 1994-05-30 | 2003-10-29 | B D Medico S.a.r.l. | Injektionsgerät |
| GB9412301D0 (en) | 1994-06-17 | 1994-08-10 | Safe T Ltd | Hollow-needle drugs etc applicators |
| RU2154462C2 (ru) | 1994-06-24 | 2000-08-20 | Айку Медикал, Инк. | Устройство для перемещения жидкости и способ его применения |
| DE69507088T2 (de) | 1994-07-27 | 1999-05-27 | Meridian Medical Technologies | Automatische Spritze |
| DE4428467A1 (de) | 1994-08-11 | 1996-02-15 | Dietmar Dr Med Enk | Spritze mit Kolbendruckdämpfung und Verfahren zur langsamen und gleichmäßigen Injektion einer Flüssigkeit mittels dieser Spritze |
| EP0781114B1 (en) | 1994-09-16 | 2005-05-25 | Ethicon Endo-Surgery, Inc. | Devices for defining and marking tissue |
| AUPM922394A0 (en) | 1994-11-03 | 1994-11-24 | Astra Pharmaceuticals Pty Ltd | Plastic syringe with overcap |
| US5637094A (en) | 1994-11-04 | 1997-06-10 | Pos-T-Vac, Inc. | Multiple dosage syringe |
| US5599302A (en) | 1995-01-09 | 1997-02-04 | Medi-Ject Corporation | Medical injection system and method, gas spring thereof and launching device using gas spring |
| US5647845A (en) | 1995-02-01 | 1997-07-15 | Habley Medical Technology Corporation | Generic intravenous infusion system |
| US5607395A (en) | 1995-02-02 | 1997-03-04 | Ragsdale; Ronald | Device for remote injection of animals |
| GB9504878D0 (en) | 1995-03-10 | 1995-04-26 | Weston Medical Ltd | Viscously coupled actuator |
| GB9506087D0 (en) | 1995-03-24 | 1995-05-10 | Owen Mumford Ltd | Improvements relating to medical injection devices |
| US5779668A (en) | 1995-03-29 | 1998-07-14 | Abbott Laboratories | Syringe barrel for lyophilization, reconstitution and administration |
| FR2733155B1 (fr) | 1995-04-18 | 1997-09-19 | Tebro | Auto-injecteur rechargeable |
| FR2733687B1 (fr) | 1995-05-04 | 1997-10-03 | Brunel Marc | Procede de fabrication d'un dispositif d'injection du type pre-rempli renfermant une dose de liquide a injecter, et dispositif d'injection realise |
| FR2736553B1 (fr) | 1995-07-12 | 1998-01-09 | Soc Et Et D Applic Tech Sedat | Seringue d'injection, notamment de produits medicaux liquides, a protecteur d'aiguille mobile |
| DE29513214U1 (de) | 1995-08-21 | 1997-01-02 | Adamaszek, Franz-Heinz, 70193 Stuttgart | Dosier- und automatisches Injektionssystem |
| US5520653A (en) | 1995-09-01 | 1996-05-28 | Medrad, Inc. | Syringe adapter for front-loading medical injector |
| US5674204A (en) | 1995-09-19 | 1997-10-07 | Becton Dickinson And Company | Medication delivery pen cap actuated dose delivery clutch |
| FR2739564B3 (fr) | 1995-10-06 | 1998-04-10 | Calomili Gerard | Seringue de securite a usage unique, dont la canule d'aiguille se retracte automatiquement et entierement apres le premier usage |
| US5658259A (en) | 1995-10-19 | 1997-08-19 | Meridian Medical Technologies, Inc. | Dental cartridge assembly auto-injector with protective needle cover |
| US5807334A (en) | 1995-10-20 | 1998-09-15 | Hodosh; Milton | Fluid dispensing apparatus |
| US6159161A (en) | 1995-10-20 | 2000-12-12 | Hodosh; Milton | Microprocessor-controlled fluid dispensing apparatus |
| US5567160A (en) | 1995-10-26 | 1996-10-22 | Survival Technology, Inc. | Autoinjector training device |
| US5997513A (en) | 1995-11-22 | 1999-12-07 | Smith; Jerry A. | Syringe cover cooperating with needle cover |
| FR2741810B1 (fr) | 1995-11-30 | 1998-02-20 | Soc Et Et D Applic Tech Sedat | Seringue pour l'injection d'un melange extemporane |
| US5899879A (en) | 1995-12-19 | 1999-05-04 | Genesis Medical Technologies, Inc. | Spring-actuated needleless injector |
| US5634906A (en) | 1995-12-27 | 1997-06-03 | Habley Medical Technology Corporation | Needle hiding shield for a dose metering syringe |
| US5609577A (en) | 1996-01-29 | 1997-03-11 | Haber; Terry M. | Automatically locking hypodermic needle hiding shield for a dose metering syringe |
| DE19603707A1 (de) | 1996-02-02 | 1997-08-07 | Carnaudmetalbox Sa | Dosiervorrichtung für komprimierbare Behältnisse |
| JPH09225029A (ja) | 1996-02-26 | 1997-09-02 | Material Eng Tech Lab Inc | 注射器及びその製造方法 |
| US5865795A (en) | 1996-02-29 | 1999-02-02 | Medi-Ject Corporation | Safety mechanism for injection devices |
| GB9606829D0 (en) | 1996-03-30 | 1996-06-05 | Jeffrey Peter | Supplying materials etc |
| IT1284642B1 (it) | 1996-05-02 | 1998-05-21 | Ermanno Greco | Perfezionamenti alle siringhe automatiche per iniezione |
| GB9612724D0 (en) | 1996-06-18 | 1996-08-21 | Owen Mumford Ltd | Improvements relating to injection devices |
| DE69724784T2 (de) | 1996-07-05 | 2004-07-15 | Novo Nordisk A/S | Vorrichtung zur automatischen einführung einer nadel |
| US5843036A (en) | 1996-08-23 | 1998-12-01 | Becton Dickinson And Company | Non-dosing cartridge for an injection device |
| US5709662A (en) | 1996-08-23 | 1998-01-20 | Becton Dickinson France, S.A. | Cartridge for an injection device |
| WO1998011927A1 (de) | 1996-09-20 | 1998-03-26 | Disetronic Licensing Ag | Abtriebsglied für den vorschub eines stopfens einer spritzampulle und stopfen hierzu |
| US5697908A (en) | 1996-09-26 | 1997-12-16 | Becton Dickinson France, S.A. | Lockable safety shield for a prefillable syringe |
| DK0930905T3 (da) | 1996-10-09 | 2006-01-23 | Hns Internat Inc | Subkutan trykinjektor |
| US5873861A (en) | 1996-11-12 | 1999-02-23 | Medrad, Inc. | Plunger systems |
| US6090897A (en) | 1996-12-09 | 2000-07-18 | Nippon Shokubai Co., Ltd. | Curable resin composition and its use |
| US5817058A (en) | 1996-12-23 | 1998-10-06 | Shaw; Thomas J. | Retractable catheter introducer structure |
| US6203530B1 (en) | 1997-01-28 | 2001-03-20 | Pos-T-Vac, Inc. | Auto-injection device |
| BR9700930A (pt) | 1997-02-07 | 1998-12-08 | Rhone Poulenc Rorer Gmbh | Unidade para venda que se destina a aplicação parenteral um dispositivo para a execução da aplicação parenteral bem como uma unidade de recarga destinada á unidade para venda acima mencionada |
| CN1190599A (zh) | 1997-02-12 | 1998-08-19 | 约尼-鲍伦斯·劳拉有限公司 | 胃肠外使用的成套商品,设备及成套备品 |
| US6159184A (en) | 1997-03-10 | 2000-12-12 | Safety Syringes, Inc. | Disposable self-shielding unit dose syringe guard |
| US6331172B1 (en) | 1997-04-14 | 2001-12-18 | Baxter International Inc. | Applicator for dispensing measured quantities with use of controlled suction |
| US5989229A (en) | 1997-05-28 | 1999-11-23 | Becton, Dickinson And Company | Needle cover assembly having self-contained drug applicator |
| US6454746B1 (en) | 1997-06-04 | 2002-09-24 | Eli Lilly And Company | Medication delivery apparatus |
| GB9714948D0 (en) | 1997-07-16 | 1997-09-17 | Owen Mumford Ltd | Improvements relating to injection devices |
| US5865804A (en) | 1997-07-16 | 1999-02-02 | Bachynsky; Nicholas | Rotary cam syringe |
| GB9716065D0 (en) | 1997-07-31 | 1997-10-01 | Owen Mumford Ltd | Improvements relating to injection devices |
| US5954738A (en) | 1997-07-31 | 1999-09-21 | Bayer Corporation | Blood sampling device with lancet damping system |
| US6171276B1 (en) | 1997-08-06 | 2001-01-09 | Pharmacia & Upjohn Ab | Automated delivery device and method for its operation |
| WO1999010030A2 (en) | 1997-08-21 | 1999-03-04 | Owen Mumford Limited | Improvements relating to injection devices |
| US6569115B1 (en) | 1997-08-28 | 2003-05-27 | Mdc Investment Holdings, Inc. | Pre-filled retractable needle injection device |
| WO1999016485A1 (en) | 1997-09-29 | 1999-04-08 | Becton Dickinson And Company | Injection device and drug cartridge for preventing cross-use of the device and drug cartridge |
| US6004296A (en) | 1997-09-30 | 1999-12-21 | Becton Dickinson France, S.A. | Lockable safety shield assembly for a prefillable syringe |
| US6090078A (en) | 1997-09-30 | 2000-07-18 | Becton, Dickinson And Company | Dampening devices and methods for needle retracting safety vascular access devices |
| IE970782A1 (en) | 1997-10-22 | 1999-05-05 | Elan Corp | An improved automatic syringe |
| US6086562A (en) | 1997-10-27 | 2000-07-11 | Sarcos, Inc. | Disposable automatic injection device |
| US6045534A (en) | 1997-10-27 | 2000-04-04 | Sarcos, Inc. | Disposable fluid injection module |
| JP2001521793A (ja) | 1997-10-30 | 2001-11-13 | ラボラトアール アゲータン | 医療用安全注射器 |
| FR2770404B1 (fr) | 1997-11-05 | 2000-01-28 | Sedat | Injecteur automatique a retraction d'aiguille en fin d'injection |
| US6015438A (en) | 1997-11-14 | 2000-01-18 | Retractable Technologies Inc. | Full displacement retractable syringe |
| US5913843A (en) | 1997-11-26 | 1999-06-22 | Jentzen; S. William | Dampening device for spring movement |
| JPH11164887A (ja) | 1997-12-05 | 1999-06-22 | Nippon Zeon Co Ltd | 筒状成形体 |
| WO1999033504A1 (en) | 1997-12-31 | 1999-07-08 | Minimed Inc. | Insertion device for an insertion set and method of using the same |
| IT1304761B1 (it) | 1998-01-20 | 2001-03-29 | Nardino Righi | Siringa monouso di sicurezza. |
| DE29801168U1 (de) | 1998-01-24 | 1999-08-12 | Medico Dev Investment Co | Injektionsgerät |
| FR2774294B1 (fr) | 1998-02-04 | 2000-04-14 | Marc Brunel | Dispositif d'injection automatique d'une dose de produit medicamenteux |
| GB9803084D0 (en) | 1998-02-14 | 1998-04-08 | Owen Mumford Ltd | Improvements relating to medical injection devices |
| CA2229522A1 (en) | 1998-04-15 | 1999-10-15 | Thomas Randall Inkpen | Needle aid |
| GB9808408D0 (en) | 1998-04-18 | 1998-06-17 | Owen Mumford Ltd | Improvements relating to injection devices |
| US6209738B1 (en) | 1998-04-20 | 2001-04-03 | Becton, Dickinson And Company | Transfer set for vials and medical containers |
| DE19819409A1 (de) | 1998-04-30 | 1999-11-11 | Schering Ag | Injektionsvorrichtung |
| AU3827699A (en) | 1998-05-07 | 1999-11-23 | Akzo Nobel N.V. | Use of interleukin-18 as vaccine adjuvant |
| DE19821933C1 (de) | 1998-05-15 | 1999-11-11 | Disetronic Licensing Ag | Vorrichtung zur Verabreichung eines injizierbaren Produkts |
| DE19822031C2 (de) | 1998-05-15 | 2000-03-23 | Disetronic Licensing Ag | Autoinjektionsgerät |
| FR2778853B1 (fr) | 1998-05-19 | 2000-12-22 | Sedat | Seringue d'injection a protecteur d'aiguille charge par un ressort |
| JP2002521147A (ja) | 1998-07-27 | 2002-07-16 | メディ−ジェクト コーポレイション | 医用注射器組立体に使用する装填機構 |
| US6358236B1 (en) | 1998-08-06 | 2002-03-19 | Baxter International Inc. | Device for reconstituting medicaments for injection |
| US6428528B2 (en) | 1998-08-11 | 2002-08-06 | Antares Pharma, Inc. | Needle assisted jet injector |
| GB9817662D0 (en) | 1998-08-13 | 1998-10-07 | Crocker Peter J | Substance delivery |
| AU5639099A (en) | 1998-09-04 | 2000-03-27 | Owen Mumford Limited | Improvements relating to fluid tranfer assemblies |
| FR2784033B1 (fr) | 1998-10-01 | 2000-12-22 | Marc Brunel | Dispositif d'injection a usage unique destine a etre pre-rempli |
| US6506177B2 (en) | 1998-10-14 | 2003-01-14 | Sergio Landau | Needle-less injection system |
| SE9803662D0 (sv) | 1998-10-26 | 1998-10-26 | Pharmacia & Upjohn Ab | Autoinjector |
| JP2000126293A (ja) | 1998-10-28 | 2000-05-09 | Shimadzu Corp | 針無注射器 |
| US20020173748A1 (en) | 1998-10-29 | 2002-11-21 | Mcconnell Susan | Reservoir connector |
| JP2002529204A (ja) | 1998-11-13 | 2002-09-10 | エラン・フアルマ・インターナシヨナル・リミテツド | 薬品を給送するシステム及び方法 |
| US6689093B2 (en) | 1998-11-18 | 2004-02-10 | Bioject, Inc. | Single-use needle-less hypodermic jet injection apparatus and method |
| US6783509B1 (en) | 1998-11-18 | 2004-08-31 | Bioject Inc. | Single-use needle-less hypodermic jet injection apparatus and method |
| US6264629B1 (en) | 1998-11-18 | 2001-07-24 | Bioject, Inc. | Single-use needle-less hypodermic jet injection apparatus and method |
| DE29822494U1 (de) | 1998-12-17 | 2000-05-04 | Medico Dev Investment Co | Injektionsgerät |
| US6036675A (en) | 1999-02-03 | 2000-03-14 | Specialized Health Products, Inc. | Safety sterile cartride unit apparatus and methods |
| GB9903475D0 (en) | 1999-02-17 | 1999-04-07 | Owen Mumford Ltd | Improvements relating to injection devices |
| IL128709A (en) | 1999-02-24 | 2004-09-27 | Teva Medical Ltd | Fluid sampling apparatus |
| US6258062B1 (en) | 1999-02-25 | 2001-07-10 | Joseph M. Thielen | Enclosed container power supply for a needleless injector |
| FR2790948B1 (fr) | 1999-03-18 | 2001-06-22 | Sedat | Dispositif de transfert bidirectionnel d'un liquide entre un flacon et une capsule |
| WO2000061209A1 (en) | 1999-04-14 | 2000-10-19 | Thomas Randall Inkpen | Needle injection-facilitating device |
| NO310224B1 (no) | 1999-04-22 | 2001-06-11 | Medical Needle As | Engangsspröyte med automatisk tilbaketrekkbar kanyle |
| US20040069044A1 (en) | 1999-04-29 | 2004-04-15 | Gilad Lavi | Device for measuring a volume of drug |
| SE9901736D0 (sv) | 1999-05-12 | 1999-05-12 | Pharmacia & Upjohn Ab | Injectino device and method for ITS operation |
| NZ335985A (en) | 1999-05-27 | 2001-04-27 | Simcro Tech Ltd | Measuring dispenser for a container |
| US6330960B1 (en) | 1999-06-04 | 2001-12-18 | Mcneil-Ppc, Inc. | Squeeze dispenser |
| DE60023511T2 (de) | 1999-07-15 | 2006-04-20 | Bracco International B.V. | Kolben für spritze |
| WO2001007104A1 (de) | 1999-07-27 | 2001-02-01 | Pharma Consult Ges.M.B.H. | Vorrichtung zum automatischen injizieren von injektionsflüssigkeiten |
| JP2001046498A (ja) | 1999-08-06 | 2001-02-20 | Shimadzu Corp | 針無注射器 |
| US6238374B1 (en) | 1999-08-06 | 2001-05-29 | Proxima Therapeutics, Inc. | Hazardous fluid infuser |
| JP3514428B2 (ja) | 1999-08-24 | 2004-03-31 | 日本ベルボン精機工業株式会社 | 三 脚 |
| US6491667B1 (en) | 1999-08-31 | 2002-12-10 | Becton, Dickinson And Company | Syringe tip cap |
| US6162199A (en) | 1999-09-20 | 2000-12-19 | Geringer; Joseph Robert | Device for loading a syringe from a vial |
| US6579269B1 (en) | 1999-09-21 | 2003-06-17 | Gennady I. Kleyman | Dosage device |
| FR2799375B1 (fr) | 1999-10-07 | 2002-01-18 | Marc Brunel | Dispositif d'injection a usage unique |
| FR2799654B1 (fr) | 1999-10-13 | 2002-01-11 | Sod Conseils Rech Applic | Dispositif pour reconstituer une solution, une suspension ou une dispersion therapeutique et procede de preparation et de conditionnement dans ce dispositif |
| US6494865B1 (en) | 1999-10-14 | 2002-12-17 | Becton Dickinson And Company | Intradermal delivery device including a needle assembly |
| US6569123B2 (en) | 1999-10-14 | 2003-05-27 | Becton, Dickinson And Company | Prefillable intradermal injector |
| US6391003B1 (en) | 1999-10-25 | 2002-05-21 | Antares Pharma, Inc. | Locking mechanism for a jet injector |
| US7029457B2 (en) | 1999-11-23 | 2006-04-18 | Felton International, Inc. | Jet injector with hand piece |
| ATE274941T1 (de) | 1999-12-08 | 2004-09-15 | Union Medico | Infusionsvorrichtung |
| US6425885B1 (en) | 1999-12-20 | 2002-07-30 | Ultradent Products, Inc. | Hydraulic syringe |
| US6926696B2 (en) | 1999-12-23 | 2005-08-09 | Owais Mohammed | Hypodermic syringe needle assembly and method of making the same |
| DK1257308T3 (da) | 2000-01-07 | 2005-09-12 | Glaxo Group Ltd | Anordning til injektion af en dosis væske, navnlig medicinsk væske |
| US6139534A (en) | 2000-01-24 | 2000-10-31 | Bracco Diagnostics, Inc. | Vial access adapter |
| US7799009B2 (en) | 2000-01-24 | 2010-09-21 | Bracco Diagnostics Inc. | Tabletop drug dispensing vial access adapter |
| US6190363B1 (en) | 2000-01-24 | 2001-02-20 | Bracco Diagnostics, Inc. | Self-aligning plunger rod |
| GB0002095D0 (en) | 2000-01-28 | 2000-03-22 | Novartis Ag | Device |
| JP2001212237A (ja) | 2000-01-31 | 2001-08-07 | Shimadzu Corp | 針無注射器 |
| US6595957B1 (en) | 2000-01-31 | 2003-07-22 | Ethicon, Inc. | Surgical fluid management system with a dampening chamber |
| DE50007821D1 (de) | 2000-02-16 | 2004-10-21 | Haselmeier S A R L | Verfahren zur rekonstitution einer injektionsflüssigkeit, und injektionsgerät zur durchführung eines solchen verfahrens |
| GB0003790D0 (en) | 2000-02-18 | 2000-04-05 | Astrazeneca Uk Ltd | Medical device |
| FR2805868A1 (fr) | 2000-03-02 | 2001-09-07 | Peugeot Citroen Automobiles Sa | Organe elastique, du type ressort a compression |
| AU2001236018A1 (en) | 2000-03-02 | 2001-09-12 | Chugai Seiyaku Kabushiki Kaisha | Prefilled syringe assembly |
| US7527607B2 (en) | 2000-03-06 | 2009-05-05 | Mdc Investment Holdings, Inc. | Hypodermic syringe with retractable needle |
| US6855130B2 (en) | 2000-03-07 | 2005-02-15 | Becton, Dickinson And Company | Passive safety device for needle of IV infusion or blood collection set |
| US6832992B2 (en) | 2000-03-07 | 2004-12-21 | Becton, Dickinson And Company | Passive safety device for needle of blood collection set |
| GB0007071D0 (en) | 2000-03-24 | 2000-05-17 | Sams Bernard | One-way clutch mechanisms and injector devices |
| US6371959B1 (en) | 2000-04-05 | 2002-04-16 | Michael E. Trice | Radiolucent position locating device and drill guide |
| US6471677B2 (en) | 2000-04-06 | 2002-10-29 | Gem Plastics, Inc. | Fluid collection device with protective shield |
| US20040241651A1 (en) | 2000-04-07 | 2004-12-02 | Alexander Olek | Detection of single nucleotide polymorphisms (snp's) and cytosine-methylations |
| US6558348B2 (en) | 2000-04-07 | 2003-05-06 | Equidyne Systems, Inc. | Low cost disposable needleless injector system for variable and fixed dose applications |
| GB0008955D0 (en) | 2000-04-12 | 2000-05-31 | Owen Mumford Ltd | An injector pack |
| US6607508B2 (en) | 2000-04-27 | 2003-08-19 | Invivotech, Inc. | Vial injector device |
| US6183134B1 (en) | 2000-05-04 | 2001-02-06 | Illinois Tool Works, Inc. | High internal force resistant peel sealable zipper |
| US6613022B1 (en) | 2000-05-05 | 2003-09-02 | Safety Syringes, Inc. | Passive needle guard for syringes |
| CN1212165C (zh) | 2000-05-15 | 2005-07-27 | 阿雷斯贸易股份有限公司 | 至少能存放一根皮下注射针头的针头存放容器 |
| US6716198B2 (en) | 2000-05-18 | 2004-04-06 | Novo Nordisk A/S | Injection device |
| US6740062B2 (en) | 2000-05-22 | 2004-05-25 | Pharmacia Ab | Medical device |
| US6517517B1 (en) | 2000-06-08 | 2003-02-11 | Mayo Foundation For Medical Education And Research | Automated injection device for administration of liquid medicament |
| US6585690B1 (en) | 2000-06-29 | 2003-07-01 | Becton Dickinson And Company | Hypodermic syringe with selectivity retractable needle |
| AUPQ867900A0 (en) | 2000-07-10 | 2000-08-03 | Medrad, Inc. | Medical injector system |
| US6986760B2 (en) | 2000-08-02 | 2006-01-17 | Becton, Dickinson And Company | Pen needle and safety shield system |
| FR2812817B1 (fr) | 2000-08-09 | 2002-10-31 | Sanofi Synthelabo | Dispositif de protection d'une aiguille de seringue |
| US20020032412A1 (en) | 2000-08-24 | 2002-03-14 | John Riemelmoser | Syringe with retractable needle and a single use syringe |
| WO2002017996A1 (en) | 2000-08-29 | 2002-03-07 | Novo Nordisk A/S | Automatic injection device with torsion function for retraction of needle |
| CA2422692A1 (en) | 2000-09-21 | 2002-03-28 | Elan Pharma International Limited | Reconstitution and injection system |
| JP3941366B2 (ja) | 2000-09-22 | 2007-07-04 | フジノン株式会社 | 注射筒装置のストッパ |
| DE10047637A1 (de) | 2000-09-26 | 2002-04-25 | Disetronic Licensing Ag | Vorrichtung zur Verabreichung eines injizierbaren Produkts |
| FR2815543B1 (fr) | 2000-10-19 | 2003-10-24 | Sedat | Seringue d'auto-injection d'un melange extemporane |
| US6793161B1 (en) | 2000-11-17 | 2004-09-21 | Isuzu Motors Limited | Needle lift damper device of injector for fuel injection and needle lift damping method |
| IT1320104B1 (it) | 2000-11-27 | 2003-11-18 | Paolo Versini | Dispositivo iniettore per trattamenti medici e cosmetici. |
| US6569085B2 (en) | 2001-08-16 | 2003-05-27 | Syntheon, Llc | Methods and apparatus for delivering a medical instrument over an endoscope while the endoscope is in a body lumen |
| SE518981C2 (sv) | 2000-12-14 | 2002-12-17 | Shl Medical Ab | Autoinjektor |
| US6387078B1 (en) | 2000-12-21 | 2002-05-14 | Gillespie, Iii Richard D. | Automatic mixing and injecting apparatus |
| US6485460B2 (en) | 2001-01-12 | 2002-11-26 | Bracco Diagnostics, Inc. | Tamper evident syringe barrel |
| WO2002056947A1 (en) | 2001-01-18 | 2002-07-25 | Medrad, Inc. | Syringe interfaces and adapters for use with medical injectors |
| US6811545B2 (en) | 2001-01-31 | 2004-11-02 | Vincent L. Vaillancourt | Safety needle |
| US6673049B2 (en) | 2001-02-15 | 2004-01-06 | Disetronic Licensing Ag | Injection device for injecting fluid |
| US6645170B2 (en) | 2001-03-05 | 2003-11-11 | Bioject Medical Technologies, Inc. | Simplified disposable needle-free injection apparatus and method |
| US6471669B2 (en) | 2001-03-05 | 2002-10-29 | Bioject Medical Technologies Inc. | Disposable needle-free injection apparatus and method |
| MXPA03007940A (es) | 2001-03-13 | 2004-10-15 | Mdc Invest Holdings Inc | Inyector de frasco de seguridad pre-relleno. |
| WO2002074361A2 (en) | 2001-03-15 | 2002-09-26 | Mdc Investment Holdings, Inc. | Retractable needle medical device for injecting fluid from a pre-filled cartridge |
| JP4450556B2 (ja) | 2001-04-06 | 2010-04-14 | ディセトロニック・ライセンシング・アクチェンゲゼルシャフト | 注入装置 |
| GB0109002D0 (en) | 2001-04-10 | 2001-05-30 | Glaxo Group Ltd | Dispenser |
| GB0109001D0 (en) | 2001-04-10 | 2001-05-30 | Glaxo Group Ltd | Dispenser |
| EP1427463A2 (en) | 2001-04-27 | 2004-06-16 | PenJet Corporation | Method and apparatus for filling or refilling a needle-less injector |
| JP4283545B2 (ja) | 2001-05-16 | 2009-06-24 | イーライ リリー アンド カンパニー | リセット簡易化式駆動アセンブリー付きの薬物注射装置 |
| US6648850B2 (en) | 2001-06-08 | 2003-11-18 | Bioject, Inc. | Durable needle-less jet injector apparatus and method |
| JP4377222B2 (ja) | 2001-07-09 | 2009-12-02 | ベクトン・ディキンソン・アンド・カンパニー | ヒンジのある針シールドと可撓性のカニューレロックを有する針シールド組立て品 |
| DE10137962A1 (de) | 2001-08-07 | 2003-02-20 | Roesch Ag Medizintechnik | Ampulle für eine Injektionseinrichtung |
| EP1425058A1 (en) | 2001-08-09 | 2004-06-09 | Becton Dickinson and Company | Retracting needle safety device |
| GB0119520D0 (en) | 2001-08-10 | 2001-10-03 | Owen Mumford Ltd | Improvements relating to injection devices |
| DE10140704A1 (de) | 2001-08-18 | 2003-03-06 | Vetter & Co Apotheker | Verfahren zur Durchmischung einer schwer löslichen pharmazeutischen Substanz mit einem Lösungsmittel und Spritze zur Anwendung des Verfahrens |
| US7235063B2 (en) | 2001-08-21 | 2007-06-26 | D'antonio Consultants International, Inc. | Hypodermic injection system |
| US7488306B2 (en) | 2001-09-26 | 2009-02-10 | Smiths Medical Asd, Inc. | Needle protection device with dampener |
| AU2002353790A1 (en) | 2001-10-03 | 2003-04-14 | Medical Instill Technologies, Inc. | Syringe and reconstitution syringe |
| FR2830765B1 (fr) | 2001-10-15 | 2004-07-23 | Plastic Omnium Cie | Dispositif de securite pour une seringue |
| US6796967B2 (en) | 2001-10-22 | 2004-09-28 | Nps Pharmaceuticals, Inc. | Injection needle assembly |
| US7569035B1 (en) | 2001-11-02 | 2009-08-04 | Meridian Medical Technologies, Inc. | Automatic injector with anti-coring needle |
| US6607510B2 (en) | 2001-11-09 | 2003-08-19 | Bioject Medical Technologies Inc. | Disposable needle-free injection apparatus and method |
| AU2002363335B2 (en) | 2001-11-09 | 2009-09-03 | Alza Corporation | Pneumatic powered autoinjector |
| DE60217382T2 (de) | 2001-11-09 | 2007-10-11 | Alza Corp. | Zusammenschiebbarer spritzenbehälter |
| EP1448255A1 (de) | 2001-11-14 | 2004-08-25 | Riemser Arzneimittel AG | Injektionseinrichtung und ampulle insbesondere für eine injektionseinrichtung |
| JP4008232B2 (ja) | 2001-11-22 | 2007-11-14 | 昭和薬品化工株式会社 | 歯科用カートリッジ式電動注射器のプランジャロッドのプランジャヘッド |
| US20030105430A1 (en) | 2001-11-30 | 2003-06-05 | Elan Pharma International Limited Wil House | Automatic injector |
| US6863659B2 (en) | 2001-12-10 | 2005-03-08 | Bruce George Sharpe | Sharp safe hydraulic retractable syringe |
| ES2605734T3 (es) | 2001-12-13 | 2017-03-16 | Becton, Dickinson And Company | Dispositivo extractor de sistema de cierre de aguja |
| JP4046998B2 (ja) | 2001-12-14 | 2008-02-13 | ロレアル | 塗布具 |
| EP1455869A2 (de) | 2001-12-19 | 2004-09-15 | Disetronic Licensing AG | Verabreichungsvorrichtung mit abtriebsglied und stopfenkappe |
| US20040143224A1 (en) | 2002-01-07 | 2004-07-22 | Jeffrey Field | Method and apparatus for inhibiting fluid loss from a syringe |
| GB0200444D0 (en) | 2002-01-10 | 2002-02-27 | Owen Mumford Ltd | Improvements relating to medical injection devices |
| US6875205B2 (en) | 2002-02-08 | 2005-04-05 | Alaris Medical Systems, Inc. | Vial adapter having a needle-free valve for use with vial closures of different sizes |
| JP3993169B2 (ja) | 2002-02-11 | 2007-10-17 | アンタレス・ファーマ・インコーポレーテッド | 皮内注射器 |
| DE10207276A1 (de) | 2002-02-21 | 2003-09-11 | Disetronic Licensing Ag | Nadel-Insertionsvorrichtung mit quer bewegbarem Halteelement |
| GB0204673D0 (en) | 2002-02-28 | 2002-04-10 | Dca Design Int Ltd | Improvements in and relating to a medicament delivery device |
| AU2003201338A1 (en) | 2002-03-20 | 2003-10-16 | Becton, Dickinson And Company | Shieldable needle assembly with biased safety shield |
| GB0206560D0 (en) | 2002-03-20 | 2002-05-01 | Glaxo Group Ltd | Novel device |
| JP4039876B2 (ja) | 2002-03-27 | 2008-01-30 | テルモ株式会社 | 薬液注入装置 |
| JP2003298253A (ja) | 2002-03-29 | 2003-10-17 | Denso Corp | 電子制御装置の筐体構造及び電子制御装置の搭載構造 |
| US6912417B1 (en) | 2002-04-05 | 2005-06-28 | Ichor Medical Systmes, Inc. | Method and apparatus for delivery of therapeutic agents |
| WO2003088893A2 (en) | 2002-04-19 | 2003-10-30 | Equidyne Systems, Inc. | Multi-component ampule |
| US20030199814A1 (en) | 2002-04-19 | 2003-10-23 | Parsons J. Stuart | Multi-component ampule |
| ES2333710T3 (es) | 2002-04-24 | 2010-02-26 | Ares Trading S.A. | Dispositivo para preparar un liquido medicinal. |
| CA2483935C (en) | 2002-05-02 | 2013-07-02 | Pa Knowledge Limited | Injection device |
| GB2388033A (en) | 2002-05-02 | 2003-11-05 | Pa Consulting Services | Automatic injection device |
| GB2396298A (en) | 2002-12-17 | 2004-06-23 | Pa Consulting Services | Injection device and drive coupling |
| US7207973B2 (en) | 2002-05-10 | 2007-04-24 | Becton, Dickinson And Company | Passive safety shield system for injection devices |
| US6808507B2 (en) | 2002-05-10 | 2004-10-26 | Cambridge Biostability Ltd. | Safety injectors |
| US6776777B2 (en) | 2002-05-10 | 2004-08-17 | Becton, Dickinson And Company | Passive safety shield system for injection devices |
| GB0211294D0 (en) | 2002-05-17 | 2002-06-26 | Owen Mumford Ltd | Improvements relating to injection devices |
| US6979316B1 (en) | 2002-05-23 | 2005-12-27 | Seedlings Life Science Ventures Llc | Apparatus and method for rapid auto-injection of medication |
| US6676630B2 (en) | 2002-06-04 | 2004-01-13 | Bioject Medical Technologies, Inc. | Needle-free injection system |
| US7156823B2 (en) | 2002-06-04 | 2007-01-02 | Bioject Inc. | High workload needle-free injection system |
| US6764465B2 (en) | 2002-06-24 | 2004-07-20 | Long Hsiung Chen | Syringe with retractable needle and safety lock |
| MY139059A (en) | 2002-06-24 | 2009-08-28 | Alza Corp | Reusable, spring driven autoinjector |
| EP3610909A1 (en) | 2002-07-02 | 2020-02-19 | PHC Holdings Corporation | Automatic administration instrument for medical use |
| AU2003212700A1 (en) | 2002-07-16 | 2004-02-02 | Eyegene Inc. | Protein for diagnosing diabetic retinopathy |
| TW572761B (en) | 2002-07-17 | 2004-01-21 | Ming-Jeng Shiu | Syringe with retraction force |
| US20040087897A1 (en) | 2002-07-31 | 2004-05-06 | Birger Hjertman | Device and method for liquid jet generation |
| US7097634B2 (en) | 2002-07-31 | 2006-08-29 | Alza Corporation | Injection device providing automatic needle retraction |
| GB2421689B (en) | 2002-08-05 | 2007-03-07 | Caretek Medical Ltd | Drug delivery system |
| FR2845052B1 (fr) | 2002-08-06 | 2005-06-24 | Fico Mirrors | Ensemble pour la liaison articulee d'un miroir retroviseur |
| US7083600B2 (en) | 2002-08-08 | 2006-08-01 | Advanced Medical Sharps, Inc. | Safety needle and shield |
| US7387623B2 (en) | 2002-08-21 | 2008-06-17 | Pfizer Inc. | Injectable pharmaceutical suspension in a two-chamber vial |
| US9486581B2 (en) | 2002-09-11 | 2016-11-08 | Becton, Dickinson And Company | Injector device with force lock-out and injection rate limiting mechanisms |
| US7160913B2 (en) | 2002-09-13 | 2007-01-09 | Thomas Jefferson University | Methods and kit for treating Parkinson's disease |
| EP1401089A1 (de) | 2002-09-18 | 2004-03-24 | Continental ISAD Electronic Systems GmbH & Co. KG | Elektrische Maschine, ausgebildet als Starter, Generator oder Starter-Generator für ein Kraftfahrzeug |
| ATE434455T1 (de) | 2002-09-24 | 2009-07-15 | Shl Group Ab | Injektionsvorrichtung |
| GB0222731D0 (en) | 2002-10-01 | 2002-11-06 | Parker David W | Improvements in or relating to hypodermic syringes |
| DE10248061A1 (de) | 2002-10-15 | 2004-05-06 | Disetronic Licensing Ag | Injektionsvorrichtung mit Leerhub |
| GB0224505D0 (en) | 2002-10-22 | 2002-11-27 | Medical House The Plc | Needles injection device |
| US6939319B1 (en) | 2002-11-20 | 2005-09-06 | Conrad Anstead | Process and device for single use, needle-free intradermal, subcutaneous, or intramuscular injections |
| KR20040043896A (ko) | 2002-11-20 | 2004-05-27 | 삼성전자주식회사 | 푸시버튼 |
| WO2004101025A2 (en) | 2003-05-09 | 2004-11-25 | Intravacc, Inc. | Needle free hypodermic injector and ampule for intradermal, subcutaneous and intramuscular injection |
| CH695926A5 (de) | 2002-11-25 | 2006-10-31 | Tecpharma Licensing Ag | Vorrichtung zum automatischen Injizieren eines Wirkstoffes. |
| CH696186A5 (de) | 2002-11-25 | 2007-02-15 | Tecpharma Licensing Ag | Vorrichtung zur Sicherung von Injektionsnadeln. |
| JP4377880B2 (ja) | 2002-11-25 | 2009-12-02 | テクファーマ・ライセンシング・アクチェンゲゼルシャフト | 薬剤を自動的に注射するための装置 |
| JP2006507061A (ja) | 2002-11-25 | 2006-03-02 | テクファーマ・ライセンシング・アクチェンゲゼルシャフト | リセット可能な解放安全装置を有する自動注射装置 |
| EP1572270A1 (de) | 2002-11-25 | 2005-09-14 | Tecpharma Licensing AG | Injektionsvorrichtung mit nadelschutz |
| GB0228483D0 (en) | 2002-12-06 | 2003-01-08 | Boots Healthcare Int Ltd | Bottle |
| US6939330B1 (en) | 2002-12-12 | 2005-09-06 | Medsolve Llc | Syringe insertion system |
| GB2396816A (en) | 2002-12-17 | 2004-07-07 | Pa Consulting Services | Injection device |
| GB0229345D0 (en) | 2002-12-17 | 2003-01-22 | Safe T Ltd | Hollow needle applicators |
| US7252651B2 (en) | 2003-01-07 | 2007-08-07 | Becton, Dickinson And Company | Disposable injection device |
| US6767336B1 (en) | 2003-01-09 | 2004-07-27 | Sheldon Kaplan | Automatic injector |
| WO2004064706A2 (en) | 2003-01-22 | 2004-08-05 | Duoject Medical Systems Inc. | Pharmaceutical delivery systems and methods for using same |
| US7678333B2 (en) | 2003-01-22 | 2010-03-16 | Duoject Medical Systems Inc. | Fluid transfer assembly for pharmaceutical delivery system and method for using same |
| US20060104968A1 (en) | 2003-03-05 | 2006-05-18 | Halozyme, Inc. | Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases |
| FR2852851B1 (fr) | 2003-03-25 | 2006-01-06 | Sedat | Dispositif de protection d'aiguille destine a une seringue, et dispositif d'injection comprenant une seringue et ce dispositif de protection |
| US7115114B2 (en) | 2003-05-02 | 2006-10-03 | Becton, Dickinson And Company | Medical device having releasable retainer |
| US6805686B1 (en) | 2003-05-06 | 2004-10-19 | Abbott Laboratories | Autoinjector with extendable needle protector shroud |
| GB0312852D0 (en) | 2003-06-05 | 2003-07-09 | Owen Mumford Ltd | Improvements relating to syringe firing mechanisms |
| US20050020980A1 (en) | 2003-06-09 | 2005-01-27 | Yoshio Inoue | Coupling system for an infusion pump |
| DE10327254B4 (de) | 2003-06-17 | 2010-01-28 | Disetronic Licensing Ag | Modulare Infusionspumpe |
| EP1491478B1 (de) | 2003-06-25 | 2007-05-09 | Müller Martini Holding AG | Ausschleuseinrichtung |
| GB2403711A (en) | 2003-07-07 | 2005-01-12 | Gw Pharma Ltd | Drug dispenser with controlled access |
| JP3883527B2 (ja) | 2003-07-17 | 2007-02-21 | ニプロ株式会社 | トランスファーニードル |
| US7500963B2 (en) | 2003-07-22 | 2009-03-10 | Safety Syringes, Inc. | Systems and methods for automatic medical injection with safeguard |
| GB2404338B (en) | 2003-07-30 | 2007-01-24 | Safe T Ltd | Actuator and containment device for a syringe |
| US20050027255A1 (en) | 2003-07-31 | 2005-02-03 | Sid Technologies, Llc | Automatic injector |
| DE20311996U1 (de) | 2003-08-01 | 2003-10-16 | Hoelzle Dieter Tech Projekte | Injektionsvorrichtung |
| US8932264B2 (en) | 2003-08-11 | 2015-01-13 | Becton, Dickinson And Company | Medication delivery pen assembly with needle locking safety shield |
| DE10339794A1 (de) | 2003-08-28 | 2005-04-07 | Tecpharma Licensing Ag | Verabreichungsvorrichtung mit einer Schutzkappenabziehvorrichtung und einer Nadelschutzhülsenblockiereinrichtung |
| DE10340586A1 (de) | 2003-09-03 | 2005-04-07 | Tecpharma Licensing Ag | Abmischvorrichtung für Mehrkammerampulle |
| DE10342058B4 (de) | 2003-09-11 | 2007-10-25 | Tecpharma Licensing Ag | Verabreichungsvorrichtung für ein injizierbares Produkt mit einer Auslösesicherung |
| US7097071B2 (en) | 2003-09-16 | 2006-08-29 | Mark L Anderson | Dispenser container technology |
| IL157981A (en) | 2003-09-17 | 2014-01-30 | Elcam Medical Agricultural Cooperative Ass Ltd | Auto injector |
| FR2860162B1 (fr) | 2003-09-26 | 2006-06-02 | Becton Dickinson France | Dispositif de protection d'un appareil d'injection |
| US20050085776A1 (en) | 2003-10-16 | 2005-04-21 | Edgar Hommann | Injection device for administering a fluid product |
| WO2005035028A1 (en) | 2003-10-16 | 2005-04-21 | Tecpharma Licensing Ag | Injection device for administering a fluid product |
| DE10348185A1 (de) | 2003-10-16 | 2005-05-19 | Tecpharma Licensing Ag | Injektionsgerät mit Nadelabdeckung |
| JP2005141729A (ja) | 2003-10-17 | 2005-06-02 | Fuji Xerox Co Ltd | 周辺機器制御プログラム、装置および方法、並びに表示制御プログラム、装置および方法 |
| FR2861310B1 (fr) | 2003-10-22 | 2006-09-22 | Plastef Investissements | Dispositif de seringue d'injection securise |
| DE10351599A1 (de) | 2003-11-05 | 2005-06-16 | Tecpharma Licensing Ag | Autoinjektionsvorrichtung |
| DE10351598A1 (de) | 2003-11-05 | 2005-06-16 | Tecpharma Licensing Ag | Autoinjektionsvorrichtung |
| US20050101919A1 (en) | 2003-11-07 | 2005-05-12 | Lennart Brunnberg | Device for an injector |
| US20050125019A1 (en) | 2003-12-05 | 2005-06-09 | Paul Kudrna | Lancet device and method |
| US7776007B2 (en) | 2003-12-05 | 2010-08-17 | Zogenix, Inc. | Device for readying a needle free injector for delivery |
| WO2005058396A1 (de) | 2003-12-18 | 2005-06-30 | Tecpharma Licensing Ag | Auslösbares injektionsgerät |
| CH696421A5 (de) | 2003-12-18 | 2007-06-15 | Tecpharma Licensing Ag | Autoinjektor mit Arretierung des Wirkstoffbehälters. |
| US20050137523A1 (en) | 2003-12-22 | 2005-06-23 | Wyatt Philip W. | Medicament administration apparatus |
| GB2410188B (en) | 2004-01-23 | 2006-01-25 | Medical House Plc | Injection device |
| AU2005205966B2 (en) | 2004-01-23 | 2010-08-05 | Shl Medical Ag | Injection device |
| FR2865407B1 (fr) | 2004-01-27 | 2006-04-28 | Crossject | Seringue sans aiguille avec un injecteur receptacle amortissant |
| US7717879B2 (en) | 2004-02-03 | 2010-05-18 | Smjm Inject Gmbh | Anesthetic syringe |
| US20050209554A1 (en) | 2004-03-19 | 2005-09-22 | Sergio Landau | Needle-free single-use cartridge and injection system |
| US20090209554A1 (en) | 2004-03-24 | 2009-08-20 | Array Biopharma Inc. | Thiazoliums as transketolase inhibitors |
| US20050222539A1 (en) | 2004-03-30 | 2005-10-06 | Pediamed Pharmaceuticals, Inc. | Automatic injection device |
| IL161660A0 (en) | 2004-04-29 | 2004-09-27 | Medimop Medical Projects Ltd | Liquid drug delivery device |
| NL1026187C2 (nl) | 2004-05-13 | 2005-11-15 | Univ Eindhoven Tech | Inrichting voor het genereren van corona-ontladingen. |
| US20050261633A1 (en) | 2004-05-19 | 2005-11-24 | Khalaj Ben M | Rechargeable handheld injection device with reversible drive having adjustable syringe cradle |
| GB2414400B (en) | 2004-05-28 | 2009-01-14 | Cilag Ag Int | Injection device |
| AU2005247153C1 (en) | 2004-05-28 | 2012-01-19 | Cilag Gmbh International | Injection device |
| GB2414404B (en) | 2004-05-28 | 2009-06-03 | Cilag Ag Int | Injection device |
| GB2414406B (en) | 2004-05-28 | 2009-03-18 | Cilag Ag Int | Injection device |
| US7717874B2 (en) | 2004-05-28 | 2010-05-18 | Bioject, Inc. | Needle-free injection system |
| DE102004026745B4 (de) | 2004-05-28 | 2013-06-20 | Justus-Liebig-Universität Giessen | Verfahren und Vorrichtung zur Ausbringung von nanoskaligen Polymerfasern als Träger für landwirtschaftliche Wirkstoffe |
| GB2414405B (en) | 2004-05-28 | 2009-01-14 | Cilag Ag Int | Injection device |
| GB2414402B (en) | 2004-05-28 | 2009-04-22 | Cilag Ag Int | Injection device |
| GB2414401B (en) | 2004-05-28 | 2009-06-17 | Cilag Ag Int | Injection device |
| GB2414399B (en) | 2004-05-28 | 2008-12-31 | Cilag Ag Int | Injection device |
| GB2414403B (en) | 2004-05-28 | 2009-01-07 | Cilag Ag Int | Injection device |
| GB2414775B (en) | 2004-05-28 | 2008-05-21 | Cilag Ag Int | Releasable coupling and injection device |
| GB2414409B (en) | 2004-05-28 | 2009-11-18 | Cilag Ag Int | Injection device |
| GB2414398B (en) | 2004-05-28 | 2009-04-22 | Cilag Ag Int | Injection device |
| US20050273054A1 (en) | 2004-06-03 | 2005-12-08 | Florida Atlantic University | Epinephrine auto-injector |
| ITMI20041471A1 (it) | 2004-07-21 | 2004-10-21 | Sergio Restelli | Kit di sicurezza per siringa standard relativa a siringa monouso di sicurezza |
| US20060100588A1 (en) | 2004-07-23 | 2006-05-11 | Lennart Brunnberg | Needle handling device |
| US7449012B2 (en) | 2004-08-06 | 2008-11-11 | Meridian Medical Technologies, Inc. | Automatic injector |
| US20060069350A1 (en) | 2004-09-30 | 2006-03-30 | Buenger David R | Medical syringe injector pen |
| US7731678B2 (en) | 2004-10-13 | 2010-06-08 | Hyprotek, Inc. | Syringe devices and methods for mixing and administering medication |
| US20060089594A1 (en) | 2004-10-26 | 2006-04-27 | Sergio Landau | Needle-free injection device |
| US20060089593A1 (en) | 2004-10-26 | 2006-04-27 | Sergio Landau | Needle-free injection device for individual users |
| US7255689B2 (en) | 2004-10-29 | 2007-08-14 | Safety Syringes, Inc. | Syringe with anti-rotation for luer lock |
| US7666168B2 (en) | 2004-11-05 | 2010-02-23 | Don Millerd | Syringe guard with selected needle configurations |
| US7412273B2 (en) | 2004-11-15 | 2008-08-12 | Biosense Webster, Inc. | Soft linear mapping catheter with stabilizing tip |
| US7297136B2 (en) | 2004-12-06 | 2007-11-20 | Wyrick Ronald E | Medicine injection devices and methods |
| US7905352B2 (en) | 2004-12-06 | 2011-03-15 | Washington Biotech Corporation | Kits containing medicine injection devices and containers |
| CN101484198A (zh) | 2004-12-09 | 2009-07-15 | 韦斯特制药服务公司 | 尾部装有固定针的注射器和具有该注射器的自动注射装置 |
| US7407494B2 (en) | 2005-01-31 | 2008-08-05 | Bostroem Anders | Device for delivering medicament |
| US8361026B2 (en) | 2005-02-01 | 2013-01-29 | Intelliject, Inc. | Apparatus and methods for self-administration of vaccines and other medicaments |
| US20060258986A1 (en) | 2005-02-11 | 2006-11-16 | Hunter Ian W | Controlled needle-free transport |
| US20060184103A1 (en) | 2005-02-17 | 2006-08-17 | West Pharmaceutical Services, Inc. | Syringe safety device |
| DE102005007614A1 (de) | 2005-02-18 | 2006-08-24 | Tecpharma Licensing Ag | Autoinjektor mit einer Auslöseverriegelung |
| US20070060904A1 (en) | 2005-03-14 | 2007-03-15 | Becton, Dickinson And Company | Filling system and method for syringes with short needles |
| GB2425062B (en) | 2005-04-06 | 2010-07-21 | Cilag Ag Int | Injection device |
| GB2427826B (en) | 2005-04-06 | 2010-08-25 | Cilag Ag Int | Injection device comprising a locking mechanism associated with integrally formed biasing means |
| GB2424838B (en) | 2005-04-06 | 2011-02-23 | Cilag Ag Int | Injection device (adaptable drive) |
| GB2424837B (en) | 2005-04-06 | 2010-10-06 | Cilag Ag Int | Injection device |
| GB2424836B (en) | 2005-04-06 | 2010-09-22 | Cilag Ag Int | Injection device (bayonet cap removal) |
| FR2884721A1 (fr) | 2005-04-20 | 2006-10-27 | Becton Dickinson France Soc Pa | Ensemble d'injection et dispositif d'assistance a l'injection |
| US7618393B2 (en) * | 2005-05-03 | 2009-11-17 | Pharmajet, Inc. | Needle-less injector and method of fluid delivery |
| US7699802B2 (en) | 2005-05-03 | 2010-04-20 | Pharmajet, Inc. | Needle-less injector |
| EP1904131A2 (en) | 2005-06-21 | 2008-04-02 | Eli Lilly And Company | Apparatus and method for injecting a pharmaceutical |
| PT1759729E (pt) | 2005-08-30 | 2010-03-04 | Cilag Gmbh Int | Conjunto de agulha para um sistema de seringa previamente cheia |
| US7944366B2 (en) | 2005-09-19 | 2011-05-17 | Lifescan, Inc. | Malfunction detection with derivative calculation |
| US20110098656A1 (en) | 2005-09-27 | 2011-04-28 | Burnell Rosie L | Auto-injection device with needle protecting cap having outer and inner sleeves |
| CN101282752A (zh) | 2005-10-11 | 2008-10-08 | 伊莱利利公司 | 用于注射药物的设备 |
| GB2431356B (en) | 2005-10-21 | 2011-02-09 | Nilufer Smith Innovations Ltd | Improvements in and relating to disposable dispensers for personal use |
| DE102005052502A1 (de) | 2005-11-03 | 2007-05-16 | Tecpharma Licensing Ag | Autoinjektor-Aktivierung Auslöseelement |
| US7682155B2 (en) | 2005-11-03 | 2010-03-23 | Meridian Medical Technologies, Inc. | Training device for an automatic injector |
| US7988675B2 (en) | 2005-12-08 | 2011-08-02 | West Pharmaceutical Services Of Delaware, Inc. | Automatic injection and retraction devices for use with pre-filled syringe cartridges |
| GB2433032A (en) | 2005-12-08 | 2007-06-13 | Owen Mumford Ltd | Syringe with dose adjustment means |
| US7657849B2 (en) | 2005-12-23 | 2010-02-02 | Apple Inc. | Unlocking a device by performing gestures on an unlock image |
| US7981101B2 (en) | 2005-12-30 | 2011-07-19 | Carefusion 303, Inc. | Medical vial adapter with reduced diameter cannula and enlarged vent lumen |
| US8926562B2 (en) | 2005-12-30 | 2015-01-06 | Hospira, Inc. | Syringe holding system |
| GB0601309D0 (en) | 2006-01-23 | 2006-03-01 | Medical House The Plc | Injection device |
| JP4741952B2 (ja) | 2006-02-02 | 2011-08-10 | Ｉｄｅｃ株式会社 | 操作スイッチ |
| GB0604459D0 (en) | 2006-03-06 | 2006-04-12 | Gramplan Health Board | Needle guidance apparatus |
| FR2899482A1 (fr) | 2006-04-11 | 2007-10-12 | Becton Dickinson France Soc Pa | Dispositif d'injection automatique |
| US7547300B2 (en) | 2006-04-12 | 2009-06-16 | Icu Medical, Inc. | Vial adaptor for regulating pressure |
| WO2007122193A1 (en) | 2006-04-21 | 2007-11-01 | Novo Nordisk A/S | Two stage jet injection device |
| WO2007131013A1 (en) | 2006-05-03 | 2007-11-15 | Antares Pharma, Inc. | Two-stage reconstituting injector |
| WO2007129324A2 (en) * | 2006-05-09 | 2007-11-15 | Gil Yigal | A disposable injecting device with auto-retraction mechanism |
| GB2437922B (en) | 2006-05-10 | 2010-12-08 | Owen Mumford Ltd | Injection device comprising a window and a shutter element |
| GB2438629B (en) | 2006-06-01 | 2011-02-23 | Cilag Gmbh Int | Injection device |
| GB2438590B (en) | 2006-06-01 | 2011-02-09 | Cilag Gmbh Int | Injection device |
| GB2438593B (en) | 2006-06-01 | 2011-03-30 | Cilag Gmbh Int | Injection device (cap removal feature) |
| GB2438591B (en) | 2006-06-01 | 2011-07-13 | Cilag Gmbh Int | Injection device |
| US7618396B2 (en) | 2006-08-09 | 2009-11-17 | Avant Medical Corp. | Injection system with hidden needles |
| US7811262B2 (en) | 2006-08-23 | 2010-10-12 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir filling and infusion medium delivery |
| US7794434B2 (en) | 2006-08-23 | 2010-09-14 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir filling and infusion medium delivery |
| US7828764B2 (en) | 2006-08-23 | 2010-11-09 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir filling and infusion medium delivery |
| US8167863B2 (en) | 2006-10-16 | 2012-05-01 | Carefusion 303, Inc. | Vented vial adapter with filter for aerosol retention |
| CA2564061A1 (en) | 2006-10-16 | 2008-04-16 | Duoject Medical Systems Inc. | Reconstitution system for mixing the contents of a vial containing a first substance with a second substance stored in a cartridge |
| WO2008047372A2 (en) | 2006-10-19 | 2008-04-24 | Elcam Medical Agricultural Cooperative Association Ltd. | Automatic injection device |
| ES2365931T3 (es) | 2006-12-13 | 2011-10-13 | Shl Group Ab | Inyector automático. |
| GB0625169D0 (en) | 2006-12-18 | 2007-01-24 | Medical House Plc The | Improved autoinjector |
| DK2125084T3 (da) | 2006-12-22 | 2011-05-16 | Novo Nordisk As | Afskærmelig nåleanordning med forspændt sikkerhedsskærm |
| US7871397B2 (en) | 2006-12-26 | 2011-01-18 | Stat Medical Devices, Inc. | Pen needle tip |
| WO2008093063A2 (en) | 2007-02-01 | 2008-08-07 | Pa Knowledge Limited | Auto injector and adaptor for covering the needle of the auto injector |
| GB2446778A (en) | 2007-02-01 | 2008-08-27 | Pa Knowledge Ltd | Syringe adaptor |
| US7883499B2 (en) | 2007-03-09 | 2011-02-08 | Icu Medical, Inc. | Vial adaptors and vials for regulating pressure |
| AU2008226638B2 (en) | 2007-03-09 | 2013-03-28 | Eli Lilly And Company | Delay mechanism for automatic injection device |
| WO2008113864A1 (de) | 2007-03-22 | 2008-09-25 | Tecpharma Licensing Ag | Injektionsvorrichtung mit auslösesicherungen |
| EP2131898B1 (en) | 2007-03-23 | 2017-08-30 | SHL Group AB | Auto injector |
| EP2139543B1 (en) | 2007-04-23 | 2018-06-06 | Sid Technologies LLC | Devices for intradermal injection |
| US7959715B2 (en) | 2007-04-30 | 2011-06-14 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir air bubble management |
| US8434528B2 (en) | 2007-04-30 | 2013-05-07 | Medtronic Minimed, Inc. | Systems and methods for reservoir filling |
| WO2008144575A2 (en) | 2007-05-18 | 2008-11-27 | Optiscan Biomedical Corporation | Fluid injection and safety system |
| JP4780034B2 (ja) | 2007-05-18 | 2011-09-28 | 株式会社島津製作所 | 針無注射器 |
| JP2008295590A (ja) | 2007-05-29 | 2008-12-11 | Terumo Corp | 穿刺器具 |
| US20080306443A1 (en) | 2007-06-06 | 2008-12-11 | Mallinckrodt Inc. | Medical Fluid Injector Having Wireless Pressure Monitoring Feature |
| US20100286714A1 (en) | 2007-07-18 | 2010-11-11 | Steffen Gyrn | Inserter device with controlled acceleration |
| GB2451665B (en) | 2007-08-08 | 2012-09-26 | Cilag Gmbh Int | Injection device |
| GB2451663B (en) | 2007-08-08 | 2012-09-26 | Cilag Gmbh Int | Injection device |
| GB2452286B (en) | 2007-08-29 | 2012-09-26 | Cilag Gmbh Int | Injection system |
| EP2211946B1 (en) | 2007-09-25 | 2017-08-09 | Becton Dickinson France | Autoinjector with trigger positionable in active position by movement of a safety shield and indication of the active position |
| ES2688900T3 (es) | 2007-11-12 | 2018-11-07 | Medicom Innovation Partner A/S | Autoinyector con ubicaciones de anclaje cambiantes para un accionador mecánico |
| WO2009114542A1 (en) * | 2008-03-10 | 2009-09-17 | Antares Pharma, Inc. | Injector safety device |
| GB2461085B (en) | 2008-06-19 | 2012-08-29 | Cilag Gmbh Int | Injection device |
| GB2461088B (en) | 2008-06-19 | 2012-09-26 | Cilag Gmbh Int | Injection device |
| GB2461089B (en) | 2008-06-19 | 2012-09-19 | Cilag Gmbh Int | Injection device |
| GB2461087B (en) | 2008-06-19 | 2012-09-26 | Cilag Gmbh Int | Injection device |
| JP5603335B2 (ja) | 2008-08-29 | 2014-10-08 | ノボ・ノルデイスク・エー／エス | 時間遅延インジケータを備える医療用注射器 |
| CN102186517B (zh) | 2008-09-18 | 2013-07-24 | 贝克顿·迪金森公司 | 具有带棘齿的柱塞的医用注射器 |
| WO2010035060A1 (en) | 2008-09-29 | 2010-04-01 | Becton Dickinson France | Automatic injection device |
| JP5430646B2 (ja) | 2008-09-30 | 2014-03-05 | テルモ株式会社 | 注射針および薬剤注射装置 |
| CN102245234B (zh) | 2008-12-12 | 2014-06-04 | Shl集团有限责任公司 | 药物传送装置 |
| EP2415493A4 (en) | 2009-03-30 | 2017-12-13 | Terumo Kabushiki Kaisha | Syringe needle assembly and medicament injection device |
| WO2010112557A1 (en) | 2009-03-31 | 2010-10-07 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device |
| GB2472578A (en) | 2009-08-10 | 2011-02-16 | Owen Mumford Ltd | Sheath removal device and needle protector |
| EP2470241B2 (en) | 2009-08-27 | 2023-08-30 | Sanofi-Aventis Deutschland GmbH | Housing component for a drug delivery device |
| BR112012010534A2 (pt) | 2009-10-30 | 2016-03-15 | Sanofi Aventis Deutschand Gmbh | "dispositivo de fornecimento de fármaco e método de montagem" |
| JP5807021B2 (ja) | 2010-02-18 | 2015-11-10 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 自動注射器 |
| UA110026C2 (uk) | 2010-03-01 | 2015-11-10 | Пристрій для автоматичного виконання ін'єкції з механізмом затримки, який включає в себе пересувальний елемент подвійного призначення | |
| WO2011117283A2 (en) | 2010-03-25 | 2011-09-29 | Sanofi-Aventis Deutschland Gmbh | Needle assembly |
| JP6165055B2 (ja) | 2010-06-28 | 2017-07-19 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 自動注射器 |
| EP2399635A1 (en) | 2010-06-28 | 2011-12-28 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
| EP2399633A1 (en) | 2010-06-28 | 2011-12-28 | Sanofi-Aventis Deutschland GmbH | Needle safety arrangement and method for operating it |
| EP2399629A1 (en) | 2010-06-28 | 2011-12-28 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
| EP2399628A1 (en) | 2010-06-28 | 2011-12-28 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
| RU2573039C2 (ru) | 2010-07-02 | 2016-01-20 | Санофи-Авентис Дойчланд Гмбх | Защитное устройство для предварительно заполненного шприца и инъекционное устройство |
| NZ604077A (en) | 2010-07-02 | 2014-07-25 | Sanofi Aventis Deutschland | Safety device for a pre-filled syringe and injection device |
| JP6057894B2 (ja) | 2010-07-02 | 2017-01-11 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 充填済みシリンジ、注射デバイスおよび注射キットのための安全デバイス |
| EP2446866A1 (en) | 2010-11-02 | 2012-05-02 | Fovea Pharmaceuticals | Apparatus for injection into an eye |
| EP2468332A1 (en) | 2010-12-21 | 2012-06-27 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
| EP2468330A1 (en) | 2010-12-21 | 2012-06-27 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
| AU2011354198B2 (en) | 2011-01-04 | 2015-10-22 | Sanofi-Aventis Deutschland Gmbh | A safety device for a pre-filled syringe and an injection device |
| JP5864607B2 (ja) | 2011-01-04 | 2016-02-17 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | プレフィルドシリンジと注射デバイス用の安全デバイス |
| EP2489380A1 (en) | 2011-02-18 | 2012-08-22 | Sanofi-Aventis Deutschland GmbH | Injection device |
| GB2488579A (en) | 2011-03-02 | 2012-09-05 | Owen Mumford Ltd | Autoinjector with "injection complete" indicator |
| EP2510911A1 (en) | 2011-04-13 | 2012-10-17 | Sanofi-Aventis Deutschland GmbH | Apparatus for intraocular injection |
| RU2618159C2 (ru) | 2011-05-12 | 2017-05-02 | БАЙЕР ХелсКер ЛЛСи | Система введения жидкости, имеющая различные системы для управления процедурой инъекции |
| BR112013032089A2 (pt) | 2011-06-17 | 2016-12-13 | Sanofi Aventis Deutschland | dispositivo de aplicação de fármacos para administrar uma dose predefinida de um fármaco |
| US8881443B2 (en) | 2011-07-20 | 2014-11-11 | Intelligun, Llc | Firearm safety lock with key-based override |
| KR20140050753A (ko) | 2011-08-31 | 2014-04-29 | 에스에이치엘 그룹 에이비 | 주사 장치 |
| US9821118B2 (en) | 2011-09-02 | 2017-11-21 | Unl Holdings Llc | Automatic reconstitution for dual chamber syringe |
| JP2014526297A (ja) | 2011-09-09 | 2014-10-06 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 独立した針挿入による自動注射器 |
| WO2013045527A1 (en) | 2011-09-29 | 2013-04-04 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device and method for a drug delivery device |
| EP2583707A1 (en) | 2011-10-21 | 2013-04-24 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
| WO2013070715A1 (en) | 2011-11-07 | 2013-05-16 | Battelle Memorial Institute | Injection devices with ergonomic enhancements |
| JP2015506211A (ja) | 2012-01-10 | 2015-03-02 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 皮内注射用の案内アセンブリ |
| CH703993A2 (de) | 2012-02-09 | 2012-03-15 | Tecpharma Licensing Ag | Injektionsgerät zur Verabreichung oder Förderung von fluidem Produkt. |
| BR122022015975B1 (pt) | 2012-05-15 | 2024-01-02 | Bristol-Myers Squibb Company | Anticorpos monoclonais, kit para o tratamento de um indivíduo afligido com um câncer, processo para medir pd-l1 membranoso em células tumorais isoladas e uso do anticorpo ou uma porção que se liga ao antígeno do mesmo |
| EP2698179A1 (en) | 2012-08-14 | 2014-02-19 | Sanofi-Aventis Deutschland GmbH | Injection device |
| ES2548695T3 (es) | 2012-09-05 | 2015-10-20 | Becton Dickinson France | Dispositivo de inyección automática |
| ES2543304T3 (es) | 2012-09-05 | 2015-08-18 | Becton Dickinson France | Dispositivo de inyección automática |
| GB2516784B (en) | 2013-06-11 | 2015-10-21 | Cilag Gmbh Int | Injection device |
| JP6829956B2 (ja) | 2016-07-01 | 2021-02-17 | 株式会社神鋼環境ソリューション | 嫌気処理方法及び嫌気処理設備 |
-
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-
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- 2014-06-11 CA CA2915185A patent/CA2915185C/en active Active
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- 2016-09-09 HK HK16110714.6A patent/HK1223863A1/zh unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030229308A1 (en) * | 2002-06-05 | 2003-12-11 | Israil Tsals | Injector adapter and combination thereof |
| CN1893992A (zh) * | 2003-12-18 | 2007-01-10 | 诺沃挪第克公司 | 具有皮肤拉紧装置的喷嘴设备 |
| WO2006106293A1 (en) * | 2005-04-06 | 2006-10-12 | Cilag Gmbh International | Injection device (modified trigger) |
| CN101541362A (zh) * | 2006-11-13 | 2009-09-23 | 西拉格国际有限公司 | 注射装置 |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110139685A (zh) * | 2016-08-26 | 2019-08-16 | 赛诺菲-安万特德国有限公司 | 用于附接到注射装置的装置 |
| US11395882B2 (en) | 2016-08-26 | 2022-07-26 | Sanofi-Aventis Deutschland Gmbh | Device for attachment to an injection device |
| CN117442814A (zh) * | 2023-07-19 | 2024-01-26 | 艾可泰科生物科技(浙江)有限公司 | 一种促进糖尿病溃疡创面愈合的干细胞局部注射装置 |
| CN117442814B (zh) * | 2023-07-19 | 2024-05-31 | 艾可泰科生物科技(浙江)有限公司 | 一种促进糖尿病溃疡创面愈合的干细胞局部注射装置 |
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| Publication number | Publication date |
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| AU2014280156B2 (en) | 2018-01-04 |
| ES2817836T3 (es) | 2021-04-08 |
| SG11201509941YA (en) | 2016-01-28 |
| BR112015030792A2 (pt) | 2017-07-25 |
| JP2016521608A (ja) | 2016-07-25 |
| EP3007746A1 (en) | 2016-04-20 |
| WO2014198799A1 (en) | 2014-12-18 |
| JP6736461B2 (ja) | 2020-08-05 |
| US20160129200A1 (en) | 2016-05-12 |
| EA201592292A1 (ru) | 2016-05-31 |
| CA2915185A1 (en) | 2014-12-18 |
| EP3007746B1 (en) | 2020-07-22 |
| NZ715352A (en) | 2018-09-28 |
| UA118449C2 (uk) | 2019-01-25 |
| MX2015017068A (es) | 2016-04-21 |
| GB201310392D0 (en) | 2013-07-24 |
| EA033787B1 (ru) | 2019-11-26 |
| HK1223863A1 (zh) | 2017-08-11 |
| GB2515039B (en) | 2015-05-27 |
| US11173255B2 (en) | 2021-11-16 |
| BR112015030792B1 (pt) | 2022-11-01 |
| GB2515039A (en) | 2014-12-17 |
| CA2915185C (en) | 2021-11-09 |
| HK1205019A1 (zh) | 2015-12-11 |
| KR20160018737A (ko) | 2016-02-17 |
| AU2014280156A1 (en) | 2015-12-17 |
| CN105339026B (zh) | 2019-08-02 |
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