CH672600A5 - - Google Patents

Download PDF

Info

Publication number
CH672600A5
CH672600A5 CH3025/86A CH302586A CH672600A5 CH 672600 A5 CH672600 A5 CH 672600A5 CH 3025/86 A CH3025/86 A CH 3025/86A CH 302586 A CH302586 A CH 302586A CH 672600 A5 CH672600 A5 CH 672600A5
Authority
CH
Switzerland
Prior art keywords
container
trough
piston
holder
housing
Prior art date
Application number
CH3025/86A
Other languages
German (de)
English (en)
Inventor
Robert Edward Newell
Paul Kenneth Rand
Robert Alexander Fitzsimmons
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26289568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CH672600(A5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB858519141A external-priority patent/GB8519141D0/en
Priority claimed from GB858525067A external-priority patent/GB8525067D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of CH672600A5 publication Critical patent/CH672600A5/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • External Artificial Organs (AREA)
  • Electrotherapy Devices (AREA)
  • Motorcycle And Bicycle Frame (AREA)
CH3025/86A 1985-07-30 1986-07-29 CH672600A5 (OSRAM)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858519141A GB8519141D0 (en) 1985-07-30 1985-07-30 Administering medicaments to patients
GB858525067A GB8525067D0 (en) 1985-10-10 1985-10-10 Administering medicaments to patients

Publications (1)

Publication Number Publication Date
CH672600A5 true CH672600A5 (OSRAM) 1989-12-15

Family

ID=26289568

Family Applications (1)

Application Number Title Priority Date Filing Date
CH3025/86A CH672600A5 (OSRAM) 1985-07-30 1986-07-29

Country Status (35)

Country Link
US (2) US4811731A (OSRAM)
EP (1) EP0211595B1 (OSRAM)
JP (1) JPS6241668A (OSRAM)
KR (1) KR940002247B1 (OSRAM)
AT (1) AT396872B (OSRAM)
AU (1) AU591152B2 (OSRAM)
BE (1) BE905189A (OSRAM)
BR (1) BR8603576A (OSRAM)
CA (1) CA1272917A (OSRAM)
CH (1) CH672600A5 (OSRAM)
CY (1) CY1481A (OSRAM)
DE (2) DE3682457D1 (OSRAM)
DK (1) DK163640C (OSRAM)
DO (1) DOP1989004707A (OSRAM)
ES (1) ES2000781A6 (OSRAM)
FI (1) FI88112C (OSRAM)
FR (1) FR2585563B1 (OSRAM)
GB (1) GB2178965B (OSRAM)
GR (1) GR861995B (OSRAM)
HK (1) HK67589A (OSRAM)
HU (1) HU199306B (OSRAM)
IE (1) IE59026B1 (OSRAM)
IL (1) IL79550A (OSRAM)
IT (1) IT1195984B (OSRAM)
KE (1) KE3865A (OSRAM)
LU (1) LU86534A1 (OSRAM)
MX (1) MX171389B (OSRAM)
NL (1) NL8601949A (OSRAM)
NO (1) NO166268C (OSRAM)
NZ (1) NZ217006A (OSRAM)
PH (1) PH26882A (OSRAM)
PL (1) PL149733B1 (OSRAM)
PT (1) PT83094B (OSRAM)
SE (1) SE8603252L (OSRAM)
SG (1) SG8789G (OSRAM)

Families Citing this family (526)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH672600A5 (OSRAM) * 1985-07-30 1989-12-15 Glaxo Group Ltd
IT1222509B (it) * 1987-08-17 1990-09-05 Miat Spa Insufflatore per la somministrazione di farmaci sotto forma di polvere predosata in opercoli
US4817789A (en) * 1987-09-23 1989-04-04 Allergan, Inc. Lens container assembly
FR2626500B1 (fr) * 1988-01-28 1990-04-27 Valois Sa Poussoir de vaporisateur agence pour operer le melange d'un additif dans l'emission du jet
CH678151A5 (en) * 1988-07-13 1991-08-15 Heinz Hermann Weick Self-medication nasal dispenser
GB8824804D0 (en) * 1988-10-22 1988-11-30 Fisons Plc Device
SE466684B (sv) * 1989-03-07 1992-03-23 Draco Ab Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator
US5176132A (en) * 1989-05-31 1993-01-05 Fisons Plc Medicament inhalation device and formulation
US5239991A (en) * 1989-06-21 1993-08-31 Fisons Plc Disposable powder medicament inhalation device with peel-off cover
IT1230313B (it) * 1989-07-07 1991-10-18 Somova Spa Inalatore per medicamenti in capsule.
DE3927170A1 (de) * 1989-08-17 1991-02-21 Boehringer Ingelheim Kg Inhalator
US5208226A (en) * 1989-09-08 1993-05-04 Glaxo Group Limited Medicaments
US5270305A (en) * 1989-09-08 1993-12-14 Glaxo Group Limited Medicaments
DK544589D0 (da) * 1989-11-01 1989-11-01 Novo Nordisk As Manuel betjent apparat til dispensering af en forudbestemt maengde af et pulverformet stof
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
US6536427B2 (en) 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
SK280968B6 (sk) 1990-03-02 2000-10-09 Glaxo Group Limited Balenie medikamentu na použite v inhalačnom prístroji
MY105368A (en) * 1990-03-02 1994-09-30 Glaxo Group Ltd Inhalation device.
GB9012870D0 (en) * 1990-06-08 1990-08-01 Glaxo Group Ltd Device
GB9015522D0 (en) * 1990-07-13 1990-08-29 Braithwaite Philip W Inhaler
IT1243344B (it) * 1990-07-16 1994-06-10 Promo Pack Sa Inalatore plurimonodose per medicamenti in polvere
SE9002895D0 (sv) * 1990-09-12 1990-09-12 Astra Ab Inhalation devices for dispensing powders i
US5429122A (en) * 1990-09-26 1995-07-04 Zanen; Pieter Inhaler devices provided with a reservoir for several doses of medium for inhaling, transporting device, whirl chamber
FR2667509B1 (fr) * 1990-10-04 1995-08-25 Valois Inhalateur a poudre, dispositif de conditionnement de microdoses de poudre sous forme de bandes adaptees a etre utilisees dans un inhalateur a poudre, et procede de fabrication de ces bandes.
NL9002706A (nl) * 1990-12-10 1992-07-01 Pharmachemie Bv Inrichting ten gebruike bij het inhaleren van in staafvormige capsules verpakte poedervormige stoffen.
US5243970A (en) * 1991-04-15 1993-09-14 Schering Corporation Dosing device for administering metered amounts of powdered medicaments to patients
US5492112A (en) * 1991-05-20 1996-02-20 Dura Pharmaceuticals, Inc. Dry powder inhaler
ES2141108T3 (es) * 1991-07-02 2000-03-16 Inhale Inc Metodo y dispositivo para proporcionar medicamentos en aerosol.
US6681767B1 (en) 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
US5337740A (en) * 1991-08-01 1994-08-16 New England Pharmaceuticals, Inc. Inhalation devices
US5161524A (en) * 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US5287850A (en) * 1991-08-20 1994-02-22 Habley Medical Technology Corporation Timing and velocity controlled powered pharmaceutical inhaler
DE4128295A1 (de) * 1991-08-27 1993-03-04 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung fuer fliessfaehige medien
USD350821S (en) 1991-11-18 1994-09-20 Smithkline Beecham P.L.C. Oral inhaler
GB9124468D0 (en) * 1991-11-18 1992-01-08 Smithkline Beecham Plc Novel device
DE4211475A1 (de) * 1991-12-14 1993-06-17 Asta Medica Ag Pulverinhalator
GB2264237A (en) * 1992-02-05 1993-08-25 Robert Edward Newell An inhaler
GB9203761D0 (en) * 1992-02-21 1992-04-08 Innovata Biomed Ltd Inhaler
EP0558879B1 (en) * 1992-03-04 1997-05-14 Astra Aktiebolag Disposable inhaler
US5301664A (en) * 1992-03-06 1994-04-12 Sievers Robert E Methods and apparatus for drug delivery using supercritical solutions
JPH0633935Y2 (ja) * 1992-03-27 1994-09-07 サカセ化学工業株式会社 グルーピングメディシンプール
ES2118234T3 (es) * 1992-05-29 1998-09-16 Ggu Gesundheits Umweltforsch Dispositivo para generar particulas inhalables de sustancias activas.
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments
US5785049A (en) * 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US6673335B1 (en) * 1992-07-08 2004-01-06 Nektar Therapeutics Compositions and methods for the pulmonary delivery of aerosolized medicaments
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
US7448375B2 (en) * 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
JPH08507452A (ja) * 1993-03-03 1996-08-13 テナックス コーポレーション 乾燥粉末状吸入器薬剤の担体
TW360548B (en) 1993-04-08 1999-06-11 Powderject Res Ltd Products for therapeutic use
US5372128A (en) * 1993-04-14 1994-12-13 Habley Medical Technology Corporation Fluidizing powder inhaler
US5533502A (en) * 1993-05-28 1996-07-09 Vortran Medical Technology, Inc. Powder inhaler with aerosolization occurring within each individual powder receptacle
BE1007408A3 (nl) * 1993-08-13 1995-06-06 Winters Joep Werkwijze en inrichting voor het controleren van het gebruik van een geneesmiddel.
US5524613A (en) * 1993-08-25 1996-06-11 Habley Medical Technology Corporation Controlled multi-pharmaceutical inhaler
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
US5388573A (en) * 1993-12-02 1995-02-14 Tenax Corporation Dry powder inhalator medicament carrier
PT101450B (pt) * 1994-02-02 1999-11-30 Hovione Produtos Farmaceuticos Novo dispositivo para inalacao
PT748213E (pt) * 1994-03-07 2004-08-31 Nektar Therapeutics Metodos e composicoes para administracao pulmonar de insulina
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
US6102036A (en) * 1994-04-12 2000-08-15 Smoke-Stop Breath activated inhaler
GB9409851D0 (en) * 1994-05-17 1994-07-06 Cambridge Consultants Improvements in and relating to containers of particulate material
CN1073119C (zh) * 1994-05-18 2001-10-17 吸入治疗系统公司 干扰素干粉配方的方法及组合物
US5483954A (en) * 1994-06-10 1996-01-16 Mecikalski; Mark B. Inhaler and medicated package
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
CA2200727C (en) * 1994-09-21 2006-11-28 Adrian E. Smith Apparatus and methods for dispersing dry powder medicaments
FR2725626A1 (fr) * 1994-10-18 1996-04-19 Sofab Dispositif pour l'inhalation de produits en poudre
DE19500764C2 (de) * 1995-01-13 2001-09-27 Sofotec Gmbh & Co Kg Vorrichtung zum Verabreichen von Medikamenten in fester, in einem Luftstrom fein verteilter Form
US5676643A (en) * 1995-02-13 1997-10-14 The Procter & Gamble Company Dispenser for friably releasing dry particulate medicaments
US5780014A (en) * 1995-04-14 1998-07-14 Inhale Therapeutic Systems Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
US5921237A (en) * 1995-04-24 1999-07-13 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5622166A (en) * 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
US5669973A (en) * 1995-06-06 1997-09-23 David Sarnoff Research Center, Inc. Apparatus for electrostatically depositing and retaining materials upon a substrate
US5714007A (en) * 1995-06-06 1998-02-03 David Sarnoff Research Center, Inc. Apparatus for electrostatically depositing a medicament powder upon predefined regions of a substrate
US20040237961A1 (en) * 1995-06-08 2004-12-02 Snow John Medlin Inhalation actuated device for use with metered dose inhalers (MDIs)
US6672304B1 (en) 1995-06-08 2004-01-06 Innovative Devices, Llc Inhalation actuated device for use with metered dose inhalers (MDIs)
DE19523516C1 (de) * 1995-06-30 1996-10-31 Asta Medica Ag Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen
US5642727A (en) * 1995-07-25 1997-07-01 David Sarnoff Research Center, Inc. Inhaler apparatus using a tribo-electric charging technique
US5988163A (en) * 1995-08-02 1999-11-23 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of delivery of medicament
US5823183A (en) * 1995-08-02 1998-10-20 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5692496A (en) * 1995-08-02 1997-12-02 Innovative Devices, Llc Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US6209538B1 (en) * 1995-08-02 2001-04-03 Robert A. Casper Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
NL1001031C1 (nl) * 1995-08-23 1997-02-25 Npk Ind Design B V Inrichting voor het afgeven van pillen uit een blisterverpakking.
US5649554A (en) * 1995-10-16 1997-07-22 Philip Morris Incorporated Electrical lighter with a rotatable tobacco supply
US5827985A (en) * 1995-12-19 1998-10-27 Endress + Hauser Gmbh + Co. Sensor apparatus for process measurement
US5669378A (en) * 1995-12-21 1997-09-23 Pera; Ivo Inhaling device
NZ324374A (en) * 1996-01-03 1999-06-29 Glaxo Group Ltd Inhalation device
USD381416S (en) * 1996-02-08 1997-07-22 Astra Aktiebolag Unit dose inhaler
USD395499S (en) 1996-04-08 1998-06-23 Dura Pharmaceuticals, Inc. Dry powder inhaler
AU134061S (en) 1996-04-11 1998-06-16 Glaxo Group Ltd Inhalation device
US5743251A (en) 1996-05-15 1998-04-28 Philip Morris Incorporated Aerosol and a method and apparatus for generating an aerosol
GB9610821D0 (en) * 1996-05-23 1996-07-31 Glaxo Wellcome Inc Metering apparatus
US5871010A (en) 1996-06-10 1999-02-16 Sarnoff Corporation Inhaler apparatus with modified surfaces for enhanced release of dry powders
US5857456A (en) * 1996-06-10 1999-01-12 Sarnoff Corporation Inhaler apparatus with an electronic means for enhanced release of dry powders
GB9616047D0 (en) 1996-07-31 1996-09-11 Glaxo Group Ltd Medicament carrier with agglomerated large medicament particles and related method of manufacture thereof
US5976574A (en) 1996-12-31 1999-11-02 Inhale Therapeutic Systems Processes for spray drying hydrophobic drugs in organic solvent suspensions
US20030203036A1 (en) * 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
US5794613A (en) * 1997-01-09 1998-08-18 Sepracor, Inc. Multiple-dose dispenser for dry powder inhalers
TW469832U (en) * 1997-03-14 2001-12-21 Astra Ab Inhalation device
US6006747A (en) * 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
US20030035778A1 (en) * 1997-07-14 2003-02-20 Robert Platz Methods and compositions for the dry powder formulation of interferon
US6237590B1 (en) * 1997-09-18 2001-05-29 Delsys Pharmaceutical Corporation Dry powder delivery system apparatus
AU139218S (en) * 1997-10-22 1999-12-15 Procter & Gamble Dispenser with cap
US6116238A (en) * 1997-12-02 2000-09-12 Dura Pharmaceuticals, Inc. Dry powder inhaler
USD412978S (en) 1997-12-02 1999-08-17 Dura Pharmaceuticals, Inc. Inhaler
US6237591B1 (en) 1998-11-02 2001-05-29 Dura Pharmaceuticals, Inc. Turbine dry powder inhaler
JP4253124B2 (ja) * 1997-12-02 2009-04-08 デュラ・ファーマシューティカルズ・インコーポレイテッド 乾燥粉末吸入器
KR100620338B1 (ko) * 1998-03-16 2006-09-13 넥타르 테라퓨틱스 에어로졸형 활성 제제 전달 방법
DE19817417A1 (de) 1998-04-18 1999-10-21 Pfeiffer Erich Gmbh & Co Kg Spender für Medien, insbesondere Pulver
US6257233B1 (en) * 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
US6149774A (en) 1998-06-10 2000-11-21 Delsys Pharmaceutical Corporation AC waveforms biasing for bead manipulating chucks
DE19831525A1 (de) * 1998-07-14 2000-01-20 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
KR100522910B1 (ko) * 1998-09-15 2005-12-21 주식회사 새 한 청량감이 우수한 폴리에스테르 가연가공사의 제조방법
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
US6234167B1 (en) 1998-10-14 2001-05-22 Chrysalis Technologies, Incorporated Aerosol generator and methods of making and using an aerosol generator
US6923979B2 (en) * 1999-04-27 2005-08-02 Microdose Technologies, Inc. Method for depositing particles onto a substrate using an alternating electric field
ES2241611T3 (es) * 1999-06-05 2005-11-01 Innovata Biomed Limited Sisstema de suministro de medicamentos.
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6606992B1 (en) 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US6730066B1 (en) * 1999-08-03 2004-05-04 Pharmacia Ab Liquid delivery container
GB9920839D0 (en) 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
GB9924415D0 (en) * 1999-10-16 1999-12-15 Glaxo Group Ltd Medicament pack
WO2001034234A1 (en) * 1999-11-11 2001-05-17 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6810872B1 (en) 1999-12-10 2004-11-02 Unisia Jecs Corporation Inhalant medicator
US20010029947A1 (en) 1999-12-17 2001-10-18 Steve Paboojian Receptacles to facilitate the extraction of powders
MY136453A (en) * 2000-04-27 2008-10-31 Philip Morris Usa Inc "improved method and apparatus for generating an aerosol"
US6883516B2 (en) * 2000-04-27 2005-04-26 Chrysalis Technologies Incorporated Method for generating an aerosol with a predetermined and/or substantially monodispersed particle size distribution
US6948494B1 (en) 2000-05-10 2005-09-27 Innovative Devices, Llc. Medicament container with same side airflow inlet and outlet and method of use
GB0015034D0 (en) * 2000-06-21 2000-08-09 Glaxo Group Ltd Inhalation device
AR028746A1 (es) * 2000-06-23 2003-05-21 Norton Health Care Ltd Cartucho de dosis previamente medidas para inhalador de polvo seco accionado por la respiracion, el inhalador y un metodo de provision de dosis previamente medidas de polvo seco
US7575761B2 (en) * 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
EP1172122A1 (en) * 2000-07-14 2002-01-16 The Technology Partnership Public Limited Company Dry powder inhaler
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
EP2067784A3 (en) 2000-08-05 2012-08-22 Glaxo Group Limited 17.beta.-carbothioate 17.alpha.-arylcarbonyloxyloxy androstane derivatives as anti-inflammatory agents
US6948492B2 (en) * 2000-08-15 2005-09-27 University Of Kentucky Research Foundation Programmable multi-dose intranasal drug delivery device
SE517229C2 (sv) * 2000-09-25 2002-05-14 Microdrug Ag Kontinuerlig inhalator för torrt pulver
GB0023654D0 (en) 2000-09-27 2000-11-08 Cambridge Consultants Device for administering doses of particulate material
US6595210B2 (en) 2000-11-27 2003-07-22 Unisia Jecs Corporation Inhalator for administering powder composition
US6701921B2 (en) * 2000-12-22 2004-03-09 Chrysalis Technologies Incorporated Aerosol generator having heater in multilayered composite and method of use thereof
US6491233B2 (en) 2000-12-22 2002-12-10 Chrysalis Technologies Incorporated Vapor driven aerosol generator and method of use thereof
US7077130B2 (en) * 2000-12-22 2006-07-18 Chrysalis Technologies Incorporated Disposable inhaler system
US6501052B2 (en) 2000-12-22 2002-12-31 Chrysalis Technologies Incorporated Aerosol generator having multiple heating zones and methods of use thereof
US6681998B2 (en) 2000-12-22 2004-01-27 Chrysalis Technologies Incorporated Aerosol generator having inductive heater and method of use thereof
US6799572B2 (en) * 2000-12-22 2004-10-05 Chrysalis Technologies Incorporated Disposable aerosol generator system and methods for administering the aerosol
WO2002062317A2 (en) * 2001-02-06 2002-08-15 Innovata Biomed Limited Bimodal dry powder formulation for inhalation
GB0103630D0 (en) 2001-02-14 2001-03-28 Glaxo Group Ltd Chemical compounds
ES2296923T3 (es) 2001-03-22 2008-05-01 Glaxo Group Limited Derivados formanilidas como agonistas del adrenorreceptor beta2.
US7025058B2 (en) 2001-04-26 2006-04-11 New England Pharmaceuticals, Inc. Metered dose delivery device for liquid and powder agents
IL158222A0 (en) 2001-04-30 2004-05-12 Glaxo Group Ltd Anti-inflammatory 17. beta-carbothioate ester derivatives of androstane with a cyclic ester group in position 17. alpha
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
US8061006B2 (en) * 2001-07-26 2011-11-22 Powderject Research Limited Particle cassette, method and kit therefor
US7176278B2 (en) 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
US6540081B2 (en) * 2001-09-06 2003-04-01 Ecolab Inc. Unit dose blister pack product dispenser
JP4191034B2 (ja) 2001-09-14 2008-12-03 グラクソ グループ リミテッド 呼吸器疾患の治療のためのフェネタノールアミン誘導体
US8337816B2 (en) 2001-09-17 2012-12-25 Glaxo Group Limited Dry powder medicament formulations
US6871647B2 (en) 2001-09-19 2005-03-29 Advent Pharmaceuticals Pty Ltd Inhaler
US6568390B2 (en) 2001-09-21 2003-05-27 Chrysalis Technologies Incorporated Dual capillary fluid vaporizing device
US6640050B2 (en) 2001-09-21 2003-10-28 Chrysalis Technologies Incorporated Fluid vaporizing device having controlled temperature profile heater/capillary tube
US7931022B2 (en) * 2001-10-19 2011-04-26 Respirks, Inc. Method and apparatus for dispensing inhalator medicament
WO2003041777A1 (en) * 2001-11-14 2003-05-22 Nektar Therapeutics Aerosolization device with improved endpiece connection
GB0128148D0 (en) 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
US6804458B2 (en) 2001-12-06 2004-10-12 Chrysalis Technologies Incorporated Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate
US6681769B2 (en) 2001-12-06 2004-01-27 Crysalis Technologies Incorporated Aerosol generator having a multiple path heater arrangement and method of use thereof
US20030168057A1 (en) * 2001-12-14 2003-09-11 Inhale Therapeutic Systems, Inc. Electronically controllable aerosol delivery
US6701922B2 (en) 2001-12-20 2004-03-09 Chrysalis Technologies Incorporated Mouthpiece entrainment airflow control for aerosol generators
US7458373B2 (en) 2002-01-15 2008-12-02 Philip Morris Usa Inc. Aerosol generator for drug formulation
JP2005527260A (ja) * 2002-01-25 2005-09-15 グラクソ グループ リミテッド 薬剤ディスペンサ
GB0201677D0 (en) * 2002-01-25 2002-03-13 Glaxo Group Ltd Medicament dispenser
GB0217199D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicament dispenser
AU2003216401A1 (en) * 2002-03-01 2003-09-16 Glaxo Group Limited Rotary blending apparatus and system
US7794965B2 (en) 2002-03-13 2010-09-14 Signum Biosciences, Inc. Method of identifying modulators of PP2A methylase
EP1494732B1 (en) 2002-03-20 2008-01-30 MannKind Corporation Inhalation apparatus
DE10212264A1 (de) 2002-03-20 2003-10-02 Boehringer Ingelheim Pharma Kristallines Mikronisat, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels
US7448184B2 (en) * 2002-03-26 2008-11-11 Glaxo Group Limited Method for forming a laminate assembly with an ultrasonic welder
GR1004350B (el) * 2002-03-29 2003-09-26 Συσκευη εισπνοων ξηρης σκονης
US20030235538A1 (en) 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
DE10216429A1 (de) 2002-04-12 2003-10-23 Boehringer Ingelheim Pharma Arzneimittel enthaltend Steroide und ein neues Anticholinergikum
GB0208609D0 (en) * 2002-04-13 2002-05-22 Glaxo Group Ltd Compositions
GB0208608D0 (en) * 2002-04-13 2002-05-22 Glaxo Group Ltd Composition
AU2003222841A1 (en) * 2002-04-25 2003-11-10 Glaxo Group Limited Phenethanolamine derivatives
GB0216562D0 (en) * 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
AU2003228683A1 (en) * 2002-04-25 2003-11-10 Glaxo Group Limited Magnetoacoustic sensor system and associated method for sensing environmental conditions
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
WO2003095005A1 (en) * 2002-05-10 2003-11-20 Chrysalis Technologies Incorporated Aerosol generator for drug formulation and methods of generating aerosol
US7089786B2 (en) * 2002-05-15 2006-08-15 Glaxo Group Limited Microelectromechanical system and method for determining temperature and moisture profiles within pharmaceutical packaging
US7185651B2 (en) * 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
EP1707205A2 (en) 2002-07-09 2006-10-04 Boehringer Ingelheim Pharma GmbH & Co. KG Pharmaceutical compositions of anticholinergics and p38 kinase inhibitors in the treatment of respiratory diseases
DE10230751A1 (de) 2002-07-09 2004-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkompositionen auf der Basis neuer Anticholinergika und EGFR-Kinase-Hemmern
GB0217196D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicament dispenser
US20050251289A1 (en) * 2002-07-25 2005-11-10 Bonney Stanley G Medicament dispenser
GB0217198D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicament dispenser
US20050268908A1 (en) * 2002-07-25 2005-12-08 Bonney Stanley G Medicament dispenser
GB0217225D0 (en) 2002-07-25 2002-09-04 Glaxo Group Ltd Medicinal compounds
US6923179B2 (en) * 2002-09-06 2005-08-02 Philip Morris Usa Inc. Aerosol generating devices and methods for generating aerosols having controlled particle sizes
EP1565256A4 (en) * 2002-09-13 2008-05-07 Glaxo Group Ltd COATED MIXING DEVICE
US6962266B2 (en) * 2002-10-04 2005-11-08 Ecolab Inc. Method and apparatus for using a unit dose dispenser
US20060205790A1 (en) * 2002-10-22 2006-09-14 Coe Diane M Medicinal arylethanolamine compounds
US6772757B2 (en) 2002-10-25 2004-08-10 Chrysalis Technologies Incorporated Concentric controlled temperature profile fluid vaporizing device
US7442839B2 (en) 2002-10-28 2008-10-28 Glaxo Group Limited Phenethanolamine derivative for the treatment of respiratory diseases
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
US6941947B2 (en) * 2002-12-18 2005-09-13 Quadrant Technologies Limited Unit dose dry powder inhaler
WO2004060260A2 (en) * 2002-12-18 2004-07-22 Glaxo Group Limited Drug delivery system with vented mouthpiece
WO2004066912A2 (en) * 2003-01-31 2004-08-12 Technion Research & Development Foundation Ltd. Anti-inflammatory compositions and uses thereof
EP1594528A1 (en) * 2003-02-11 2005-11-16 Boehringer Ingelheim International GmbH New pharmaceutical compositions based on anticholinergics and soluble tnf receptor fusion proteins
EP1594540A1 (en) * 2003-02-11 2005-11-16 Boehringer Ingelheim International GmbH New pharmaceutical compositions based on anticholinergics and anti-tnf antibodies
GB0303396D0 (en) 2003-02-14 2003-03-19 Glaxo Group Ltd Medicinal compounds
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
DE10317461A1 (de) 2003-04-16 2004-10-28 Boehringer Ingelheim Pharma Gmbh & Co. Kg Radioaktiv markierte Mikropartikel, Verfahren zu deren Herstellung und deren Verwendung
US20040245279A1 (en) * 2003-05-05 2004-12-09 Bradley Tareasa L. System for dispensing an active ingredient using a dispensable tablet, dispensable tablet and container for holding such dispensable tablets
TW200510298A (en) 2003-06-13 2005-03-16 Theravance Inc Substituted pyrrolidine and related compounds
EP1488819A1 (en) * 2003-06-16 2004-12-22 Rijksuniversiteit te Groningen Dry powder inhaler and method for pulmonary inhalation of dry powder
GB0315509D0 (en) * 2003-07-02 2003-08-06 Meridica Ltd Dispensing device
GB0316335D0 (en) * 2003-07-11 2003-08-13 Glaxo Group Ltd Pharmaceutical formulations
TW200519108A (en) 2003-07-17 2005-06-16 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
GB0317374D0 (en) 2003-07-24 2003-08-27 Glaxo Group Ltd Medicament dispenser
CA2534132C (en) 2003-07-29 2013-11-26 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising betamimetics and an anticholinergic
US7367334B2 (en) 2003-08-27 2008-05-06 Philip Morris Usa Inc. Fluid vaporizing device having controlled temperature profile heater/capillary tube
US6991131B2 (en) * 2003-09-02 2006-01-31 Ecolab, Inc. Distributable container and system and method using distributable container
NZ546730A (en) 2003-09-24 2008-04-30 Medi Stream Pty Ltd Medication holder
AU2004273547B2 (en) * 2003-09-24 2006-07-06 Tianda Pharmaceuticals (Australia) Pty Ltd Medication holder
TW200811171A (en) 2003-10-14 2008-03-01 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
AR046114A1 (es) 2003-10-17 2005-11-23 Glaxo Group Ltd Compuesto de 8- azoniabiciclo (3.2.1) octano, composicion farmaceutica para el tratamiento de enfermedades mediadas por receptores de acetilcolina muscarinicos y uso del compuesto para preparar dicha composicion
GB2407042B (en) * 2003-10-17 2007-10-24 Vectura Ltd Inhaler
GB0324654D0 (en) * 2003-10-22 2003-11-26 Glaxo Group Ltd Medicinal compounds
GB0324897D0 (en) * 2003-10-24 2003-11-26 Glaxo Group Ltd Composition
GB0324886D0 (en) * 2003-10-24 2003-11-26 Glaxo Group Ltd Medicinal compounds
WO2005044173A1 (en) * 2003-10-27 2005-05-19 Oriel Therapeutics, Inc. Blister packages and associated methods of fabricating dry powder drug containment systems
JP2007509941A (ja) * 2003-10-28 2007-04-19 グラクソ グループ リミテッド ラクトース無水物を用いる吸入医薬製剤およびその投与方法
GB0325627D0 (en) * 2003-11-03 2003-12-10 Glaxo Group Ltd A hand-held capsule device
ATE478071T1 (de) 2003-11-03 2010-09-15 Boehringer Ingelheim Int Verfahren zur herstellung neuer tiotropiumsalze
DK1682541T3 (da) 2003-11-03 2010-06-28 Boehringer Ingelheim Int Fremgangsmåde til fremstilling af tiotropiumsalte
PE20050489A1 (es) 2003-11-04 2005-09-02 Glaxo Group Ltd Antagonistas de receptores de acetilcolina muscarinicos
GB0329182D0 (en) 2003-12-17 2004-01-21 Glaxo Group Ltd Chemical compounds
US8147426B2 (en) * 2003-12-31 2012-04-03 Nipro Diagnostics, Inc. Integrated diagnostic test system
GB2410947B (en) * 2004-02-11 2008-09-17 Cambridge Lab Ltd Pharmaceutical compounds
TWI341836B (en) 2004-03-11 2011-05-11 Theravance Inc Biphenyl compounds useful as muscarinic receptor antagonists
JP2007529513A (ja) 2004-03-17 2007-10-25 グラクソ グループ リミテッド M3ムスカリン性アセチルコリン受容体アンタゴニスト
BRPI0509382A (pt) 2004-04-02 2007-09-18 Glaxo Group Ltd processo para a preparação de um sal monocloridrato de composto, monocloridrato cristalino, processo para obter monocloridrato cristalino, método para a profilaxia ou o tratamento de uma condição clìnica em um mamìfero, uso de monocloridrato cristalino, formulação farmacêutica, e, combinação
CA2562386C (en) 2004-04-21 2014-11-18 Innovata Biomed Limited Inhaler
DK2422786T3 (da) 2004-04-22 2014-11-17 Boehringer Ingelheim Int Nye lægemiddelkombinationer til behandling af luftvejssygdomme
US20050272726A1 (en) * 2004-04-22 2005-12-08 Boehringer Ingelheim International Gmbh Novel medicaments for the treatment of respiratory diseases
US7861712B2 (en) * 2004-04-23 2011-01-04 Manta Product Development Sealed capsule including an integrated puncturing mechanism
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
MY144753A (en) 2004-04-27 2011-10-31 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
US7611709B2 (en) * 2004-05-10 2009-11-03 Boehringer Ingelheim Pharma Gmbh And Co. Kg 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives
US7727962B2 (en) * 2004-05-10 2010-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder comprising new compositions of oligosaccharides and methods for their preparation
US7723306B2 (en) * 2004-05-10 2010-05-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation
US7598267B2 (en) 2004-05-13 2009-10-06 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
US20050256115A1 (en) * 2004-05-14 2005-11-17 Boehringer Ingelheim International Gmbh Aerosol formulation for the inhalation of beta-agonists
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
WO2005110519A1 (en) * 2004-05-17 2005-11-24 Sun Pharmaceutical Industries Limited Dry powder inhaler
SE530006C2 (sv) * 2004-06-18 2008-02-05 Mederio Ag Inhalator som använder balja
US7896195B2 (en) * 2004-06-08 2011-03-01 Ecolab Inc. Tablet dispenser with isolated product hopper
WO2006009776A2 (en) * 2004-06-17 2006-01-26 Signal Investment & Management Co. Reusable support device with therapeutic inserts
US20060035893A1 (en) 2004-08-07 2006-02-16 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
US20060079544A1 (en) * 2004-08-13 2006-04-13 Boehringer Ingelheim International Gmbh Medicaments for the prevention or treatment of alveolar pneumonia comprising an anticholinergic
GB0418278D0 (en) 2004-08-16 2004-09-15 Glaxo Group Ltd Medicament dispenser
DK1786784T3 (da) 2004-08-20 2011-02-14 Mannkind Corp Katalyse af diketopiperazinsyntese
EP2314298B1 (en) 2004-08-23 2015-05-27 MannKind Corporation Microparticles comprising diketopiperazine salts for drug delivery
GB0418738D0 (en) * 2004-08-23 2004-09-22 3M Innovative Properties Co Medicinal aerosol formulation receptacle and production thereof
WO2006047663A2 (en) * 2004-10-26 2006-05-04 The University Of North Carolina At Chapel Hill Aerosol generation of therapeutic agents
JP2006130143A (ja) * 2004-11-08 2006-05-25 Hitachi Ltd 吸入式投薬器及び薬剤カートリッジ
US20060120972A1 (en) * 2004-11-09 2006-06-08 Peter Engels 9-(N-methyl-piperidyliden-4)-thioxanthene for treatment of pulmonary hypertension
US20080042823A1 (en) * 2004-11-12 2008-02-21 Heasley Matthew G Sensor System with Acoustic Transducer
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
PL2486942T3 (pl) 2004-11-24 2019-05-31 Meda Pharmaceuticals Inc Kompozycje zawierające azelastynę oraz sposoby ich stosowania
GB0427853D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
GB0427856D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Maniflod for use in medicament dispenser
GB0427858D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
MX2007008459A (es) * 2005-01-11 2007-07-25 Glaxo Group Ltd Sales de cinamato de un agonista beta-2 adrenergico.
WO2006084033A1 (en) * 2005-02-03 2006-08-10 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
US7923041B2 (en) 2005-02-03 2011-04-12 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
WO2006086130A2 (en) * 2005-02-10 2006-08-17 Glaxo Group Limited Process for crystallizing lactose particles for use in pharmaceutical formulations
MX2007009656A (es) 2005-02-10 2007-11-07 Glaxo Group Ltd Proceso para elaborar lactosa utilizando tecnicas de clasificacion previa y formulaciones farmaceuticas formadas de la misma.
PE20100737A1 (es) 2005-03-25 2010-11-27 Glaxo Group Ltd Nuevos compuestos
AR053450A1 (es) 2005-03-25 2007-05-09 Glaxo Group Ltd Derivados de 3,4-dihidro-pirimido(4,5-d)pirimidin-2-(1h)-ona 1,5,7 trisustituidos como inhibidores de la quinasa p38
GB0507711D0 (en) 2005-04-15 2005-05-25 Vectura Group Plc Improved blister piercing
US9345745B2 (en) * 2005-04-29 2016-05-24 Bo Wang Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO short peptides
US9585932B2 (en) 2005-04-29 2017-03-07 Peter C. Dowling Use of EPO-derived peptide fragments for the treatment of neurodegenerative disorders
WO2007052154A2 (en) 2005-04-29 2007-05-10 University Of Medicine And Dentistry Of New Jersey Erythropoietin-derived short peptide and its mimics as immuno/inflammatory modulators
EP1881980B1 (en) 2005-05-02 2012-08-22 Boehringer Ingelheim International GmbH Novel crystalline forms of tiotropium bromide
CA2608273C (en) 2005-05-18 2015-10-20 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
US8524734B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
CA2611907A1 (en) * 2005-06-17 2006-12-21 Boehringer Ingelheim International Gmbh Mrp iv inhibitors for the treatment of respiratory diseases
DE102005030733A1 (de) 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
GB0514501D0 (en) * 2005-07-14 2005-08-24 Cambridge Lab Ireland Ltd Pharmaceutical compounds
US20070012316A1 (en) * 2005-07-14 2007-01-18 Joann Truza Disposable compact rescue inhaler
US8763605B2 (en) 2005-07-20 2014-07-01 Manta Devices, Llc Inhalation device
GB0515584D0 (en) * 2005-07-28 2005-09-07 Glaxo Group Ltd Medicament dispenser
GB0516168D0 (en) * 2005-08-05 2005-09-14 Cambridge Lab Ireland Ltd Pharmaceutical compounds
ES2530991T3 (es) * 2005-08-15 2015-03-09 Boehringer Ingelheim Int Procedimiento para la obtención de betamiméticos
JP2009504768A (ja) 2005-08-18 2009-02-05 グラクソ グループ リミテッド ムスカリン性アセチルコリン受容体アンタゴニスト
CA2620123C (en) * 2005-08-24 2011-11-22 The Board Of Trustees Of The Leland Stanford Junior University Methods for treating and monitoring inflammation and redox imbalance in cystic fibrosis
US20090192227A1 (en) * 2005-08-24 2009-07-30 Rabindra Tirouvanziam N-Acetylcysteine Compositions and Methods for Treating Acute Exacerbations of Inflammatory Lung Disease
US20070178141A1 (en) * 2005-09-07 2007-08-02 Bebaas, Inc. Vitamin B12 compositions
US20130131007A1 (en) 2005-09-07 2013-05-23 Bebaas, Inc. Vitamin b12 compositions
US8227408B2 (en) * 2005-09-07 2012-07-24 Neurotez, Inc. Leptin as an anti-amyloidogenic biologic and methods for delaying the onset and reducing Alzheimer's disease-like pathology
US7481331B2 (en) * 2005-09-09 2009-01-27 Manrex Limited Dispensing container for a blister pack of medications
EP1928423B1 (en) 2005-09-14 2015-12-09 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
US20070086957A1 (en) 2005-10-10 2007-04-19 Thierry Bouyssou Combination of medicaments for the treatment of respiratory diseases
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
DE102005057685A1 (de) * 2005-12-01 2007-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator und Speicher für eine trockene Arzneimittelformulierung sowie diesbezügliche Verfahren und Verwendung
AR058289A1 (es) * 2005-12-12 2008-01-30 Glaxo Group Ltd Colector para ser usado en dispensador de medicamento
AR058290A1 (es) * 2005-12-12 2008-01-30 Glaxo Group Ltd Dispensador de medicamento
DE102005059602A1 (de) 2005-12-14 2007-06-21 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Mikronisierung
DK1986679T3 (da) 2006-02-22 2017-11-20 Mannkind Corp Fremgangsmåde til forbedring af mikropartiklers farmaceutiske egenskaber omfattende diketopiperazin og et aktivt indholdsstof
CA2644679C (en) * 2006-03-03 2013-12-03 Stc.Unm Dry powder inhaler with aeroelastic dispersion mechanism
US8127763B2 (en) * 2006-03-03 2012-03-06 Stc.Unm Dry powder inhaler with aeroelastic dispersion mechanism
DE102006016904A1 (de) * 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
EP1844805A1 (de) * 2006-04-13 2007-10-17 Boehringer Ingelheim Pharma GmbH & Co.KG Inhalator
EP1844808A1 (de) * 2006-04-13 2007-10-17 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG Medikamenten-Ausgabevorrichtung
PT103481B (pt) 2006-05-16 2008-08-01 Hovione Farmaciencia S A Inalador de uso simples e método de inalação
CA2653048C (en) 2006-05-19 2014-12-09 Valspar Sourcing, Inc. Coating system for cement composite articles
CN101489613A (zh) * 2006-07-14 2009-07-22 阿斯利康(瑞典)有限公司 用于对干粉状药物进行给药的吸入系统和递送装置
US20090324510A1 (en) 2006-08-07 2009-12-31 Boehringer Ingelheim International Gmbh Drug combinations for the treatment of respiratory tract diseases
UY30552A1 (es) * 2006-08-22 2008-03-31 Boehringer Ingelheim Int Combinaciones farmacologiicas en base a derivados sustituidos de la n-(5-{2-[1,1-dimetil-propilamino]-1-hidroxi-metil}-2-hidroxi-fenil)-metansulfonamida y aplicaciones
DE102006045788A1 (de) 2006-09-26 2008-03-27 Alfred Von Schuckmann Spender für pulverförmige Massen
AU2007309412B2 (en) 2006-10-25 2011-10-20 Novartis Ag Powder dispersion apparatus, method of making and using the apparatus, and components that can be used on the apparatus and other devices
GB0622827D0 (en) * 2006-11-15 2006-12-27 Glaxo Group Ltd Sheet driver for use in a drug dispenser
EP1925295A1 (de) 2006-11-22 2008-05-28 Boehringer Ingelheim Pharma GmbH & Co. KG Stabile Pulverformulierung enthaltend ein Anticholinergikum
US9034815B2 (en) * 2007-01-10 2015-05-19 Moerae Matrix, Inc Polypeptide for treating or preventing adhesions
DK2617431T3 (en) 2007-01-10 2017-07-10 Purdue Research Foundation Polypeptide inhibitors of HSP27 kinase and applications therefor
AR065804A1 (es) 2007-03-23 2009-07-01 Smithkline Beecham Corp Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento
US20080237082A1 (en) * 2007-03-29 2008-10-02 R. P. Scherer Technologies, Inc. Child resistant device for housing blister packs
AT505246B8 (de) * 2007-06-01 2009-06-15 Croma Pharma Gmbh Container für eine mehrzahl von einzeldosen sowie applikator für derartige container
US11224704B2 (en) 2007-07-06 2022-01-18 Manta Devices, Llc Dose delivery device for inhalation
CN101795723B (zh) 2007-07-06 2013-06-19 蒙塔设备有限公司 用于存储和输送药物的吸入装置
WO2009021137A2 (en) 2007-08-07 2009-02-12 Purdue Research Foundation Kinase inhibitors and uses thereof
EP2093219A1 (de) 2008-02-22 2009-08-26 Boehringer Ingelheim International Gmbh Kristalline, enantiomerenreine Salzform eines Betamimetikums und dessen Verwendung als Arzneimittel
AU2009226019C1 (en) 2008-03-20 2014-02-20 Virun, Inc. Emulsions including a PEG-derivative of tocopherol
MX2010010214A (es) * 2008-03-20 2010-12-21 Virun Inc Derivados de vitamina e y sus usos.
AU2009248914A1 (en) * 2008-05-21 2009-11-26 Neurotez, Inc. Methods for Treating Neurodegenerative Disorders Related to Neurofibrillary Tangles
CA3153292A1 (en) 2008-06-13 2009-12-17 Mannkind Corporation A dry powder inhaler and system for drug delivery
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
GB0810857D0 (en) * 2008-06-13 2008-07-23 Cambridge Lab Ireland Ltd Pharmaceutical compounds
US9358352B2 (en) 2008-06-13 2016-06-07 Mannkind Corporation Dry powder drug delivery system and methods
CN103751892B (zh) 2008-06-20 2017-03-01 曼金德公司 用于对吸入工作进行实时描绘的交互式设备和方法
US8337931B2 (en) * 2008-06-23 2012-12-25 Virun, Inc. Compositions containing non-polar compounds
JP5339794B2 (ja) * 2008-07-04 2013-11-13 キヤノン株式会社 吸入装置
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
GB2462611A (en) * 2008-08-12 2010-02-17 Cambridge Lab Pharmaceutical composition comprising tetrabenazine
US20110053866A1 (en) * 2008-08-12 2011-03-03 Biovail Laboratories International (Barbados) S.R.L. Pharmaceutical compositions
GB2463451A (en) 2008-09-08 2010-03-17 Cambridge Lab 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia
GB2463452A (en) * 2008-09-08 2010-03-17 Cambridge Lab Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof
GB2463283A (en) * 2008-09-08 2010-03-10 Cambridge Lab 3,11b-cis-dihydrotetrabenazine for use in treating asthma
WO2010036836A1 (en) 2008-09-26 2010-04-01 Oriel Therapeutics, Inc. Dry powder inhalers with dual piercing members and related devices and methods
US8550071B2 (en) 2008-09-26 2013-10-08 Oriel Therapeutics, Inc. Inhalers with airway disks having discrete airway channels and related disks and methods
ES2550309T3 (es) * 2008-09-26 2015-11-06 Oriel Therapeutics, Inc. Mecanismos inhaladores con perforadores predispuestos radialmente y métodos relacionados
US9050427B2 (en) * 2008-09-30 2015-06-09 Oriel Therapeutics, Inc. Dry powder inhalers with multi-facet surface deagglomeration chambers and related devices and methods
EP2328645B1 (en) * 2008-10-01 2015-11-11 Oriel Therapeutics, Inc. Dry powder inhalers with rotating piercing mechanisms and related devices and methods
HRP20201150T8 (hr) * 2008-10-07 2021-06-25 Horizon Orphan Llc Inhalacija levofloksacina za smanjenje upale pluća
LT2344129T (lt) * 2008-10-07 2018-05-10 Horizon Orphan Llc Aerozolinės fluorchinolono kompozicijos, skirtos farmakokinetikų pagerinimui
WO2010054017A1 (en) * 2008-11-04 2010-05-14 Nikolaos Tezapsidis Leptin compositions and methods for treating progressive cognitive function disorders resulting from accumulation of neurofibrillary tangles and amlyoid beta
AU2009324661A1 (en) * 2008-12-10 2011-07-07 Purdue Research Foundation Cell-permeant peptide-based inhibitor of kinases
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US8550074B2 (en) 2009-01-15 2013-10-08 Manta Devices, Llc Delivery device and related methods
GB0901520D0 (en) 2009-01-30 2009-03-11 Vectura Delivery Devices Ltd Inhaler
CN104523661A (zh) * 2009-02-06 2015-04-22 南加利福尼亚大学 含有单萜的治疗组合物
US20120129820A1 (en) 2009-02-09 2012-05-24 Boehringer Ingelheim International Gmbh New pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
PL3578169T3 (pl) 2009-02-26 2024-09-02 Glaxo Group Limited Preparaty farmaceutyczne zawierające 4-{(1r)-2-[(6-{2-[(2,6-dichlorobenzylo)oksy]etoksy}heksylo)amino]-1-hydroksyetylo}-2-(hydroksymetylo)fenol
MX2011009512A (es) 2009-03-11 2011-11-29 Mannkind Corp Aparato, sistema y metodo para medir la resistencia de un inhalador.
EP2405747A4 (en) * 2009-03-13 2013-01-16 Nucitec Sa De Cv COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF CARDIOVASCULAR DISEASES
US8508732B2 (en) 2009-03-18 2013-08-13 Mannkind Corporation Inhaler adaptor for a laser diffraction apparatus and method for measuring particle size distribution
CN102647979B (zh) 2009-06-12 2015-03-04 曼金德公司 具有确定比表面积的二酮哌嗪颗粒
EP2443134A2 (en) 2009-06-16 2012-04-25 Schering Corporation NOVEL [3,2-c]HETEROARYL STEROIDS AS GLUCOCORTICOID RECEPTOR AGONISTS, COMPOSITIONS AND USES THEREOF
WO2011005645A1 (en) 2009-07-06 2011-01-13 Boehringer Ingelheim International Gmbh Polymorph of [4,6-bis(dimethylamino)-2-(4-{[4-(trifluoromethyl)benzoyl]amino}benzyl)pyrimidin-5-yl]
EP2453894B1 (en) 2009-07-15 2015-11-04 Theravance Biopharma R&D IP, LLC Crystalline freebase form of a biphenyl compound
RU2576032C2 (ru) 2009-07-24 2016-02-27 Амазентис Са Соединения, композиции и способы защиты здоровья головного мозга при нейродегенеративных расстройствах
US9890195B2 (en) * 2009-07-27 2018-02-13 Purdue Research Foundation MK2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration
CA2938650C (en) 2009-09-04 2018-01-09 Raptor Pharmaceuticals Inc. Use of aerosolized levofloxacin for treating cystic fibrosis
WO2011035128A1 (en) * 2009-09-17 2011-03-24 Mutual Pharmaceutical Company, Inc. Method of treating asthma with antiviral agents
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
US9492625B2 (en) 2009-11-12 2016-11-15 Stc.Unm Dry powder inhaler with flutter dispersion member
CN102666499A (zh) 2009-11-24 2012-09-12 贝林格尔.英格海姆国际有限公司 制备嘧啶-5-基乙酸衍生物胆碱盐的多晶型的方法
US20120302584A1 (en) 2009-11-24 2012-11-29 Boehringer Ingelheim International Gmbh Novel salts forms of pyrimidin-5-yl acetic acid derivative
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
US10210216B2 (en) * 2009-12-18 2019-02-19 Sybase, Inc. Dynamic attributes for mobile business objects
CA2828833C (en) 2010-03-03 2020-11-03 Neonc Technologies Inc. Pharmaceutical compositions comprising monoterpenes
WO2011116293A2 (en) 2010-03-19 2011-09-22 Manta Devices, Llc Delivery device and related methods
WO2011119228A1 (en) 2010-03-23 2011-09-29 Virun, Inc. Nanoemulsion including sucrose fatty acid ester
USD641076S1 (en) 2010-03-26 2011-07-05 Oriel Therapeutics, Inc. Dry powder inhaler
USD635246S1 (en) 2010-03-26 2011-03-29 Oriel Therapeutics, Inc. Dose disk for dry powder inhalers
US8741373B2 (en) 2010-06-21 2014-06-03 Virun, Inc. Compositions containing non-polar compounds
ES2600928T3 (es) 2010-08-27 2017-02-13 Neonc Technologies Inc. Composiciones farmacéuticas que comprenden derivados de alcohol perilílico
US20160038600A1 (en) 2012-08-03 2016-02-11 Neonc Technologies Inc. Pharmaceutical compositions comprising poh derivatives
JP5792308B2 (ja) 2010-08-31 2015-10-07 グラクソ グループ リミテッドGlaxo Group Limited 水分制御特性を示す乾燥粉末吸入薬物製品及びその投与方法
JP5792307B2 (ja) 2010-08-31 2015-10-07 グラクソ グループ リミテッドGlaxo Group Limited 水分制御特性を示す乾燥粉末吸入薬物製品及びその投与方法
SG190793A1 (en) 2010-11-11 2013-07-31 Agency Science Tech & Res Targeting metabolic enzymes in human cancer
JP6050758B2 (ja) 2010-12-07 2016-12-21 レスピラ セラピューティクス インコーポレイテッドRespira Therapeutics,Inc. 乾燥粉末吸入器及びその作動方法
CN103517892B (zh) 2010-12-17 2016-01-27 尼昂克技术公司 使用异紫苏醇的方法和装置
JP6021117B2 (ja) 2011-01-31 2016-11-02 ジェノア ファーマシューティカルズ,インク. エアロゾルのピルフェニドンおよびピリドンアナログの化合物、および、その使用
SG194034A1 (en) 2011-04-01 2013-11-29 Mannkind Corp Blister package for pharmaceutical cartridges
US9890200B2 (en) 2011-04-12 2018-02-13 Moerae Matrix, Inc. Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition
EP2696888B1 (en) 2011-04-12 2018-12-05 Moerae Matrix, Inc., Compositions and methods for preventing or treating pulmonary fibrosis
CA2836643C (en) 2011-05-19 2017-11-14 Savara, Inc. Dry powder vancomycin compositions and associated methods
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
US8528569B1 (en) 2011-06-28 2013-09-10 Kyle D. Newton Electronic cigarette with liquid reservoir
US11103659B2 (en) 2011-07-06 2021-08-31 Manta Devices, Llc Delivery device and related methods
GB201116641D0 (en) 2011-09-27 2011-11-09 Glaxo Group Ltd Novel compounds
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
EP2589381B1 (en) 2011-11-04 2016-08-31 Rabindra Tirouvanziam Compositions for improving or preserving lung function in a patient with a pulmonary disorder
EP2809780B1 (en) 2012-02-01 2018-05-02 Protalix Ltd. Dnase i polypeptides, polynucleotides encoding same, methods of producing dnase i and uses thereof in therapy
US10874122B2 (en) 2012-02-10 2020-12-29 Virun, Inc. Beverage compositions containing non-polar compounds
US10463815B2 (en) 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
US10525216B2 (en) 2012-02-21 2020-01-07 Respira Therapeutics, Inc. Powder dispersion methods and devices
US20150044305A1 (en) 2012-03-07 2015-02-12 Advanced Inhalation Therapies (Ait) Ltd. Inhalation of nitric oxide for treating respiratory diseases
WO2013134636A1 (en) 2012-03-09 2013-09-12 Purdue Research Foundation Compositions and methods for delivery of kinase inhibiting peptides
EP2841416A1 (en) 2012-04-27 2015-03-04 Glaxo Group Limited Novel compounds
GB201207406D0 (en) 2012-04-27 2012-06-13 Glaxo Group Ltd Novel compounds
US9649454B2 (en) 2012-05-03 2017-05-16 Manta Devices, Llc Delivery device and related methods
WO2013176638A1 (en) 2012-05-25 2013-11-28 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi An inhaler comprising a mouthpiece having an improved air channel
CN104619369B (zh) 2012-07-12 2018-01-30 曼金德公司 干粉药物输送系统和方法
DK2892524T3 (da) 2012-09-04 2021-01-25 Eleison Pharmaceuticals LLC Forebyggelse af pulmonalt kræfttilbagefald med lipid-komplekseret cisplatin
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
WO2014085474A1 (en) 2012-11-28 2014-06-05 Intercept Pharmaceuticals, Inc. Treatment of pulmonary disease
GB201301192D0 (en) 2013-01-23 2013-03-06 Vectura Delivery Devices Ltd A blister piercing element for a dry powder inhaler
JP6523247B2 (ja) 2013-03-15 2019-05-29 マンカインド コーポレイション 微結晶性ジケトピペラジン粒子の製造方法および乾燥粉末組成物の製造方法
US9351517B2 (en) 2013-03-15 2016-05-31 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and compositions containing same
DK177788B1 (en) 2013-07-12 2014-07-07 Liita Holdings Ltd Inhaler
KR102321339B1 (ko) 2013-07-18 2021-11-02 맨카인드 코포레이션 열-안정성 건조 분말 약제학적 조성물 및 방법
US20150044288A1 (en) 2013-07-31 2015-02-12 Windward Pharma, Inc. Aerosol tyrosine kinase inhibitor compounds and uses thereof
WO2015021064A1 (en) 2013-08-05 2015-02-12 Mannkind Corporation Insufflation apparatus and methods
US9693574B2 (en) 2013-08-08 2017-07-04 Virun, Inc. Compositions containing water-soluble derivatives of vitamin E mixtures and modified food starch
JP6506291B2 (ja) 2013-09-10 2019-04-24 ボード オブ リージェンツ オブ ザ ユニヴァーシティ オブ テキサス システム 短縮型大腸腺腫性ポリポーシス(apc)タンパク質を標的にする治療剤
US10039321B2 (en) 2013-11-12 2018-08-07 Vmr Products Llc Vaporizer
US10058129B2 (en) 2013-12-23 2018-08-28 Juul Labs, Inc. Vaporization device systems and methods
US10076139B2 (en) 2013-12-23 2018-09-18 Juul Labs, Inc. Vaporizer apparatus
KR102256888B1 (ko) 2013-12-23 2021-05-31 쥴 랩스, 인크. 기화 디바이스 시스템 및 방법
USD769438S1 (en) * 2014-01-08 2016-10-18 Glaxo Group Limited Inhaler device
JP7066321B2 (ja) 2014-01-10 2022-05-13 アヴァリン ファーマ インク. エアロゾルのピルフェニドン及びピリドンのアナログの化合物、及び、その使用
US10709173B2 (en) 2014-02-06 2020-07-14 Juul Labs, Inc. Vaporizer apparatus
TW202535264A (zh) 2014-02-06 2025-09-16 美商尤爾實驗室有限公司 用於產生可吸入氣膠之汽化裝置
US12279646B2 (en) 2014-02-06 2025-04-22 Juul Labs, Inc. Cartridge of vaporization device systems having unequal transverse cartridge dimensions
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10336788B2 (en) 2014-04-17 2019-07-02 Moerae Matrix, Inc. Inhibition of cardiac fibrosis in myocardial infarction
WO2015164142A1 (en) * 2014-04-24 2015-10-29 Questa Corporation Multi-size pill splitter and methods
EP3137140B1 (en) * 2014-05-02 2019-07-10 Manta Devices, LLC Delivery device
EP3142694A2 (en) 2014-05-12 2017-03-22 Glaxosmithkline Intellectual Property (No. 2) Limited Pharmaceutical compositions comprising danirixin for treating infectious diseases
US10940279B2 (en) * 2014-07-01 2021-03-09 Jennifer K. Keener Aromatherapy device
US10082496B2 (en) 2014-09-10 2018-09-25 Board Of Regents Of The University Of Texas System Targeting emopamil binding protein (EBP) with small molecules that induce an abnormal feedback response by lowering endogenous cholesterol biosynthesis
US10016363B2 (en) 2014-09-18 2018-07-10 Virun, Inc. Pre-spray emulsions and powders containing non-polar compounds
US9861611B2 (en) 2014-09-18 2018-01-09 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and soft gel compositions, concentrates and powders containing same
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
WO2016057693A1 (en) 2014-10-10 2016-04-14 Alnylam Pharmaceuticals, Inc. Methods and compositions for inhalation delivery of conjugated oligonucleotide
DK3212212T3 (da) 2014-10-31 2020-12-21 Univ Monash Pulverformulering
AU2015350151A1 (en) 2014-11-17 2017-06-01 Moerae Matrix, Inc. Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition
CA2970140A1 (en) 2014-12-10 2016-06-16 Hyperstem, SA Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brain tumors
BR112017014737A2 (pt) 2015-01-08 2018-01-16 Moerae Matrix Inc formulação de peptídeos inibidores de mk2
EP3261441B1 (en) 2015-02-12 2020-09-09 Neonc Technologies Inc. Pharmaceutical compositions comprising perillyl alcohol derivatives
EP3061501A1 (en) 2015-02-27 2016-08-31 Rottapharm Ltd. Composition for the treatment of acne
AU2016231122A1 (en) 2015-03-11 2017-09-07 Glaxosmithkline Intellectual Property Development Limited TSLP binding proteins
HK1249433A1 (zh) 2015-03-12 2018-11-02 Moerae Matrix, Inc. 含有mk2抑制剂肽的组合物用於治疗非小细胞肺癌的用途
US10179215B2 (en) 2015-03-19 2019-01-15 Altria Client Services Llc Vaporizer for vaporizing a constituent of a plant material
AU2016201131B2 (en) * 2015-03-30 2020-04-02 Manrex Limited Dispensing container for blister pack of medication
US9937154B2 (en) 2015-06-10 2018-04-10 Hackensak University Medical Center Use of telmisartan to prevent and treat graft versus host disease and other alloimmune and autoimmune diseases
JP2018517732A (ja) 2015-06-15 2018-07-05 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited Nrf2レギュレーター
ES2834490T3 (es) 2015-06-15 2021-06-17 Glaxosmithkline Ip Dev Ltd Reguladores de NRF2
HRP20202036T1 (hr) 2015-06-15 2021-02-19 Glaxosmithkline Intellectual Property Development Limited Regulatori nrf2
CN107949279A (zh) 2015-07-06 2018-04-20 得克萨斯系统大学评议会 可用作用于治疗人类癌症的抗癌剂的苯甲酰胺或苯扎明化合物
EP3322417B1 (en) 2015-07-15 2023-08-23 The Board of Regents of The University of Texas System Targeting emopamil binding protein (ebp) with small molecules that induce an abnormal feedback response by lowering endogenous cholesterol biosynthesis
EP3117825A1 (en) 2015-07-16 2017-01-18 Rottapharm S.p.A. Oral formulation comprising berberine and morus alba extract
CN105013054B (zh) * 2015-07-30 2018-11-09 中山市美捷时包装制品有限公司 一种多胶囊型干粉吸入装置
CN104984448B (zh) * 2015-07-30 2018-05-01 中山市美捷时包装制品有限公司 一种干粉吸入器
UY36851A (es) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas
US10351530B2 (en) 2015-10-06 2019-07-16 Glaxosmithkline Intellectual Property Development Limited Arylcyclohexyl pyrazoles as NRF2 regulators
JP2018529745A (ja) 2015-10-06 2018-10-11 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited Nrf2レギュレーターとしてのビアリールピラゾール
EP3377045A1 (en) 2015-11-18 2018-09-26 Glaxosmithkline Intellectual Property (No. 2) Limited Pharmaceutical compositions of ribavirin
US11833118B2 (en) 2016-01-20 2023-12-05 Flurry Powders, Llc Encapsulation of lipophilic ingredients in dispersible spray dried powders suitable for inhalation
US10328216B2 (en) 2016-01-20 2019-06-25 Flurry Powders, Llc Encapsulation of lipophilic ingredients in dispensible spray dried powders suitable for inhalation
USD861975S1 (en) 2016-02-08 2019-10-01 Juul Labs, Inc. Vaporizer device with cartridges
DE202017007467U1 (de) 2016-02-11 2021-12-08 Juul Labs, Inc. Befüllbare Verdampferkartusche
WO2017139675A1 (en) 2016-02-11 2017-08-17 Pax Labs, Inc. Securely attaching cartridges for vaporizer devices
JP7185529B2 (ja) * 2016-02-24 2022-12-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 吸入器
UA126061C2 (uk) 2016-02-25 2022-08-10 Джуул Лебз, Інк. Системи та способи керування випарним пристроєм
ES2877763T3 (es) 2016-09-20 2021-11-17 Glaxosmithkline Ip No 2 Ltd Antagonistas del trpv4
TW201825458A (zh) 2016-09-20 2018-07-16 英商葛蘭素史克智慧財產(第二)有限公司 Trpv4拮抗劑
WO2018055527A1 (en) 2016-09-20 2018-03-29 Glaxosmithkline Intellectual Property (No.2) Limited Trpv4 antagonists
ES2992873T3 (en) 2016-11-30 2024-12-19 Univ Southern California A perillyl alcohol-3 bromopyruvate conjugate and methods of treating cancer
KR20190088404A (ko) 2016-12-06 2019-07-26 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 3-(2,3-디히드로-1h-인덴-5-일)프로판산 유도체 및 nrf2 조절제로서의 그의 용도
US10426698B2 (en) * 2016-12-08 2019-10-01 Breeden Brothers, LLC Pill container with cap
WO2018109642A1 (en) 2016-12-12 2018-06-21 Glaxosmithkline Intellectual Property Development Limited N-aryl pyrazoles as nrf2 regulators
EP3551620A1 (en) 2016-12-12 2019-10-16 GlaxoSmithKline Intellectual Property Development Limited 3-carboxylic acid pyrroles as nrf2 regulators
JP2020502129A (ja) 2016-12-14 2020-01-23 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited Nrf2アクチベーターとしての3−オキソ−1,4−ジアゼピニル化合物
US11117905B2 (en) 2016-12-14 2021-09-14 Glaxosmithkline Intellectual Property Development Limited Bisaryl heterocycles as NRF2 activators
ES2901617T3 (es) 2016-12-14 2022-03-23 Glaxosmithkline Ip Dev Ltd Bisarilamidas como reguladores de NRF2
JP7110197B2 (ja) 2016-12-15 2022-08-01 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド Nrf2アクチベーター
US11059816B2 (en) 2016-12-15 2021-07-13 Glaxosmithkline Intellectual Property Development Limited Ether linked triazoles as NRF2 activators
WO2018174938A1 (en) 2017-03-23 2018-09-27 Virun, Inc. Stable dry powders and emulsions containing probiotics and mucoadhesive protein
US11014941B2 (en) 2017-04-24 2021-05-25 Cocrystal Pharma, Inc. Pyrrolopyrimidine derivatives useful as inhibitors of influenza virus replication
US20210177861A1 (en) 2017-12-11 2021-06-17 Glaxosmithkline Intellectual Property Development Limited Nrf2 activator for the treatment of acute lung injury, acute respiratory distress syndrome and multiple organ dysfunction syndrome
WO2019116231A1 (en) 2017-12-11 2019-06-20 Glaxosmithkline Intellectual Property Development Limited Nrf2 activator for the treatment of acute lung injury, acute respiratory distress syndrome and multiple organ dysfunction syndrome
GB201720989D0 (en) 2017-12-15 2018-01-31 Glaxosmithkline Ip Dev Ltd Chemical compounds
MA51611A (fr) 2018-01-17 2021-04-21 Glaxosmithkline Ip Dev Ltd Inhibiteurs de pi4kiiibêta
CN119868317A (zh) 2018-02-08 2025-04-25 南加州大学 穿透血脑屏障的方法
US11643407B2 (en) 2018-05-23 2023-05-09 Glaxosmithkline Intellectual Property Development Limited Indanes as NRF2 activators
WO2020023813A1 (en) 2018-07-27 2020-01-30 Cocrystal Pharma, Inc. Pyrrolo[2,3-b]pyridin derivatives as inhibitors of influenza virus replication
ES2937837T3 (es) 2018-09-10 2023-03-31 Cocrystal Pharma Inc Inhibidores de piridopirazina y piridotriazina de la replicación del virus de la gripe
WO2020081751A1 (en) 2018-10-17 2020-04-23 Cocrystal Pharma, Inc. Combinations of inhibitors of influenza virus replication
CN120078782A (zh) 2018-11-13 2025-06-03 共晶制药公司 流感治疗剂的配制物
US20220048897A1 (en) 2018-11-26 2022-02-17 Cocrystal Pharma, Inc. Inhibitors of influenza virus replication
WO2020135920A1 (en) * 2018-12-28 2020-07-02 Université Libre de Bruxelles Kit for inhaled chemotherapy, and treatment of lung cancer with said kit
DE102020100550A1 (de) * 2019-01-14 2020-07-16 Alfred Von Schuckmann Vorrichtung zum Inhalieren pulverförmiger Substanzen, Substanzbehälter für eine solche Vorrichtung sowie Verfahren zum Befüllen einer derartigen Vorrichtung
DE102020100551A1 (de) 2019-01-14 2020-07-16 Alfred Von Schuckmann Vorrichtung zum Inhalieren pulverförmiger Substanzen
DE102019134285A1 (de) 2019-01-15 2020-07-16 Nuuvera Deutschland GmbH Vorrichtung und Verfahren zum Extrahieren und Aspirieren von Wirkstoffen, insbesondere aus der Cannabispflanze
PE20212261A1 (es) 2019-03-14 2021-11-29 Om Pharma Sa Extractos bacterianos estables como farmacos
BR112021018086A2 (pt) 2019-03-14 2021-11-23 Univ Arizona Método de tratamento e/ou prevenção de asma, exacerbações de asma, asma alérgica e/ou condições associadas com microbiota relacionadas a distúrbios respiratórios
GB201908536D0 (en) 2019-06-13 2019-07-31 Glaxosmithkline Ip Dev Ltd Compounds
DE202019104547U1 (de) * 2019-08-19 2020-11-26 Rpc Formatec Gmbh Spender
USD943158S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Vaporizer cartridge
USD943160S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Vaporizer device
USD943161S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Vaporizer device
USD943159S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Component for a vaporizer cartridge
US20230151034A1 (en) 2020-03-17 2023-05-18 Cocrystal Pharma, Inc. Peptidomimetic n5-methyl-n2-(nonanoyl-l-leucyl)-l-glutaminate derivatives, triazaspiro[4.14]nonadecane derivatives and similar compounds as inhibitors of norovirus and coronavirus replication
JP7721561B2 (ja) 2020-04-10 2025-08-12 コクリスタル ファーマ,インコーポレイテッド ノロウイルス及びコロナウイルス複製の阻害剤
EP4138884A1 (en) 2020-04-20 2023-03-01 Sorrento Therapeutics, Inc. Pulmonary administration of ace2 polypeptides
WO2022175425A1 (en) 2021-02-22 2022-08-25 Glaxosmithkline Intellectual Property Development Limited Inhaled mtor kinase inhibitors for use in the treatment or the prevention of a respiratory rna virus infection
WO2022179967A1 (en) 2021-02-23 2022-09-01 Glaxosmithkline Intellectual Property (No.2) Limited Vadadustat for treating covid-19 in a hospitalized subject
US20240189523A1 (en) 2021-04-14 2024-06-13 The University Of North Carolina At Chapel Hill Hot porous-solid metering systems and methods for generation of therapeutic aerosols by evaporation/condensation
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
MX2024001540A (es) 2021-08-03 2024-06-12 Cocrystal Pharma Inc Inhibidores para coronavirus.
WO2023028364A1 (en) 2021-08-27 2023-03-02 Sepelo Therapeutics, Llc Targeted compositions and uses therof
WO2023205389A1 (en) 2022-04-22 2023-10-26 Quench Medical Inc. Dry powder inhalation delivery of pharmaceuticals
WO2023232976A1 (en) 2022-06-03 2023-12-07 Ags Therapeutics Sas Extracellular vesicles from genetically-modified microalgae containing endogenously-loaded cargo, their preparation, and uses
WO2024095105A1 (de) * 2022-11-04 2024-05-10 Skietta Ag Vaporizer zur verdampfung eines inhalationsmediums

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB190707525A (en) * 1906-04-07 1907-11-28 Eugene Joseph Decoll Impovements relating to Appliances for Administering Anestetics
GB190706553A (en) * 1907-03-19 1907-11-28 Hume Purdie Surgical Apparatus for the Administration of Anaesthetics
US1383270A (en) * 1918-10-02 1921-06-28 Henning Albert Means for cooling internal-combustion engines and other machinery
US2386877A (en) * 1943-07-27 1945-10-16 Jr William E Neilson Box opener and dispenser
US3949751A (en) * 1970-03-03 1976-04-13 Fisons Limited Method and device for dispensing medicament to the body
US3888253A (en) * 1972-08-04 1975-06-10 Beecham Group Ltd Device for administration of medicines
GB1392945A (en) * 1972-08-23 1975-05-07 Fisons Ltd Inhalation device
GB1387954A (en) * 1973-05-08 1975-03-19 Miles Lab Insufflator
US4014336A (en) * 1975-01-13 1977-03-29 Syntex Puerto Rico, Inc. Inhalation device
GB1562732A (en) * 1976-02-10 1980-03-12 Allen & Hanburys Ltd Device for dispensing medicaments
DE2834135C3 (de) * 1978-08-03 1981-11-26 SIEMENS AG AAAAA, 1000 Berlin und 8000 München Verfahren zum Herstellen einer Wanderfeldröhre
DE2835135C3 (de) * 1978-08-10 1982-03-04 Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart Wirkstoff-Speicher für ein Inhalationsgerät
IT1116047B (it) * 1979-04-27 1986-02-10 Sigma Tau Ind Farmaceuti Dispositivo per la rapida inalazione di farmaci in polvere da parte di persone sofferenti di asma
NL8020393A (OSRAM) * 1979-10-30 1981-09-01 Riker Laboratories, Inc. Te Loughborough, Groot-Brittannie.
GB2061735B (en) * 1979-10-30 1983-11-30 Riker Laboratories Inc Breath actuated device for administration of powdered medicaments by inhalation
EP0041783B1 (en) * 1980-06-06 1984-12-05 FISONS plc Inhalation device for powdered medicaments
ES506585A0 (es) * 1980-10-30 1982-09-01 Riker Laboratories Inc Un dispositivo para facilitar la inhalacion oral de medica- mentos en forma de polvo
US4384649A (en) * 1980-12-11 1983-05-24 E. R. Squibb & Sons, Inc. Dispensing package
EP0062571B1 (fr) * 1981-03-27 1985-09-25 Erca Holding, S.A.R.L. Procédé et dispositif de perçage d'un couvercle de récipient, et installation de fabrication du dispositif
NO160330C (no) * 1982-10-08 1989-04-12 Glaxo Group Ltd Anordning for aa administrere medikamenter til pasienter og medikamentpakning for anordningen.
ZA837318B (en) * 1982-10-08 1985-06-26 Glaxo Group Ltd Device for administering medicaments to patients
GB8314308D0 (en) * 1983-05-24 1983-06-29 Matburn Holdings Ltd Medical administration devices
DE3345722A1 (de) * 1983-12-17 1985-06-27 Boehringer Ingelheim KG, 6507 Ingelheim Inhalator
CH672600A5 (OSRAM) * 1985-07-30 1989-12-15 Glaxo Group Ltd
US4690279A (en) * 1986-03-13 1987-09-01 Charles Hochberg Birth control pill dispenser in the form of a hair brush

Also Published As

Publication number Publication date
AU6065586A (en) 1987-02-12
SE8603252D0 (sv) 1986-07-29
FI88112C (fi) 1993-04-13
GB2178965B (en) 1988-08-03
IL79550A0 (en) 1986-10-31
IE59026B1 (en) 1993-12-15
PT83094A (pt) 1987-01-26
BR8603576A (pt) 1987-03-04
PT83094B (pt) 1993-07-30
US5035237A (en) 1991-07-30
EP0211595A2 (en) 1987-02-25
HK67589A (en) 1989-09-01
GB8618466D0 (en) 1986-09-03
BE905189A (fr) 1987-01-29
DK163640C (da) 1992-08-17
ATA204086A (de) 1993-05-15
FR2585563A1 (fr) 1987-02-06
JPH0577433B2 (OSRAM) 1993-10-26
NO863062D0 (no) 1986-07-29
NL8601949A (nl) 1987-02-16
CY1481A (en) 1989-12-08
PL260858A1 (en) 1987-04-21
DE3625685A1 (de) 1987-03-12
FI863094A0 (fi) 1986-07-29
KR870000937A (ko) 1987-03-10
FR2585563B1 (fr) 1993-11-12
IT8648322A0 (it) 1986-07-29
MX171389B (es) 1993-10-22
FI88112B (fi) 1992-12-31
CA1272917A (en) 1990-08-21
NO166268C (no) 1991-07-03
DOP1989004707A (es) 1997-10-17
DK360986A (da) 1987-01-31
KE3865A (en) 1989-05-19
SE8603252L (sv) 1987-01-31
SG8789G (en) 1989-07-07
US4811731A (en) 1989-03-14
GB2178965A (en) 1987-02-25
EP0211595B1 (en) 1991-11-13
IL79550A (en) 1991-06-10
FI863094L (fi) 1987-01-31
NZ217006A (en) 1989-04-26
LU86534A1 (fr) 1987-09-03
DK163640B (da) 1992-03-23
HUT44182A (en) 1988-02-29
KR940002247B1 (ko) 1994-03-19
PL149733B1 (en) 1990-03-31
HU199306B (en) 1990-02-28
IT1195984B (it) 1988-11-03
AU591152B2 (en) 1989-11-30
JPS6241668A (ja) 1987-02-23
PH26882A (en) 1992-11-16
DE3625685C2 (OSRAM) 1990-05-03
ES2000781A6 (es) 1988-03-16
EP0211595A3 (en) 1988-10-05
NO863062L (no) 1987-02-02
GR861995B (en) 1986-11-04
AT396872B (de) 1993-12-27
DE3682457D1 (de) 1991-12-19
NO166268B (no) 1991-03-18
IE862022L (en) 1987-01-30
DK360986D0 (da) 1986-07-29

Similar Documents

Publication Publication Date Title
DE3625685C2 (OSRAM)
AT396333B (de) Vorrichtung zur verabreichung von medikamenten an patienten, einrichtung mit mehreren solchen vorrichtungen und traeger mit medikamentbehaeltern hiefuer
DE69004749T2 (de) Einrichtung zur Inhalation eines Medikaments.
DE69530079T2 (de) Vorrichtung zur verabreichung von einzelnen gaben eines medikaments
DE69101600T2 (de) Inhalationsvorrichtung zur mehrfachen Ausgabe von Einzeldosen pulverförmiger Arzneimittel.
EP3099359B1 (de) Pulverinhalator und pulverinhalationsset
EP0147755B1 (de) Inhalator
DE4106379C2 (de) Inhalationsgerät und Medikamentenpackung hierfür
DE69617431T2 (de) Arzneipulverkartusche mit integrierter dosiereinrichtung, sowie pulverinhalator
DE102014005647B4 (de) Pulverinhalator und Pulverinhalatorset
DE69521472T2 (de) Inhaliervorrichtung für pulverförmige Substanzen
DE69424310T2 (de) Pulverinhalator
DE3046108C2 (OSRAM)
DE60115480T2 (de) Inhalationsgerät
DE4436051C2 (de) Vorrichtung zum Betätigen von Aerosolabgabegeräten
DE2625925A1 (de) Inhaliervorrichtung
CH656311A5 (de) Durch atemluft betaetigte vorrichtung zum oralen inhalieren eines medikamentes in pulverform.
DE7924612U1 (de) Inhalationsvorrichtung zur abgabe eines pulverfoermigen medikaments
DE19500764C2 (de) Vorrichtung zum Verabreichen von Medikamenten in fester, in einem Luftstrom fein verteilter Form
DE4118674A1 (de) Medikamentenaufnahmebehaelter und ausgabevorrichtung
AT389665B (de) Instrument zum herauspressen eines objektes aus einer in einem traeger definierten aufnahme
EP4076605B1 (de) Inhalator
DE1566604C3 (de) Vorrichtung zum oralen Inhalieren von Medikamenten in fein verteilter Form
DE10218997B4 (de) Vorrichtung zur Einzelentnahme von Medikamenten aus einer Blisterverpackung
DE19750872A1 (de) Vorrichtung zum Inhalieren pulverförmiger Substanzen

Legal Events

Date Code Title Description
PL Patent ceased