CA3022202A1 - Combinations of linagliptin and metformin - Google Patents
Combinations of linagliptin and metformin Download PDFInfo
- Publication number
- CA3022202A1 CA3022202A1 CA3022202A CA3022202A CA3022202A1 CA 3022202 A1 CA3022202 A1 CA 3022202A1 CA 3022202 A CA3022202 A CA 3022202A CA 3022202 A CA3022202 A CA 3022202A CA 3022202 A1 CA3022202 A1 CA 3022202A1
- Authority
- CA
- Canada
- Prior art keywords
- metformin
- patients
- stage
- linagliptin
- egfr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16174075 | 2016-06-10 | ||
| EP16174075.8 | 2016-06-10 | ||
| EP17154248 | 2017-02-01 | ||
| EP17154248.3 | 2017-02-01 | ||
| PCT/EP2017/064007 WO2017211979A1 (en) | 2016-06-10 | 2017-06-08 | Combinations of linagliptin and metformin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3022202A1 true CA3022202A1 (en) | 2017-12-14 |
Family
ID=59067646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3022202A Pending CA3022202A1 (en) | 2016-06-10 | 2017-06-08 | Combinations of linagliptin and metformin |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US10155000B2 (enExample) |
| EP (2) | EP3468562A1 (enExample) |
| JP (3) | JP2019517542A (enExample) |
| KR (1) | KR102391564B1 (enExample) |
| CN (1) | CN109310697A (enExample) |
| AU (2) | AU2017276758A1 (enExample) |
| BR (1) | BR112018072401A2 (enExample) |
| CA (1) | CA3022202A1 (enExample) |
| CL (1) | CL2018003361A1 (enExample) |
| MX (1) | MX390363B (enExample) |
| PH (1) | PH12018502593A1 (enExample) |
| WO (1) | WO2017211979A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
| EP1852108A1 (en) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | DPP IV inhibitor formulations |
| MX2008014024A (es) | 2006-05-04 | 2008-11-14 | Boehringer Ingelheim Int | Formas poliformas. |
| PE20110235A1 (es) | 2006-05-04 | 2011-04-14 | Boehringer Ingelheim Int | Combinaciones farmaceuticas que comprenden linagliptina y metmorfina |
| PE20140960A1 (es) | 2008-04-03 | 2014-08-15 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
| KR20200118243A (ko) * | 2008-08-06 | 2020-10-14 | 베링거 인겔하임 인터내셔날 게엠베하 | 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료 |
| US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
| AR083878A1 (es) | 2010-11-15 | 2013-03-27 | Boehringer Ingelheim Int | Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento |
| ES2929025T3 (es) | 2012-05-14 | 2022-11-24 | Boehringer Ingelheim Int | Linagliptina, un derivado de xantina como inhibidor de dpp-4, para su uso en el tratamiento del SRIS y/o de la septicemia |
| US20130303462A1 (en) | 2012-05-14 | 2013-11-14 | Boehringer Ingelheim International Gmbh | Use of a dpp-4 inhibitor in podocytes related disorders and/or nephrotic syndrome |
| BR112018072401A2 (pt) | 2016-06-10 | 2019-02-19 | Boehringer Ingelheim International Gmbh | combinações de linagliptina e metformina |
| EP3665705B1 (en) | 2017-08-08 | 2024-12-18 | Fresenius Medical Care Holdings, Inc. | Systems and methods for treating and estimating progression of chronic kidney disease |
| BR112020026164A2 (pt) * | 2018-07-17 | 2021-03-23 | Boehringer Ingelheim International Gmbh | terapia antidiabética cardioprotetora e nefroprotetora |
| CN115137785B (zh) * | 2022-07-21 | 2023-06-20 | 湖北省中医院 | 用于治疗特发性膜性肾病的膜肾方 |
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2017
- 2017-06-08 BR BR112018072401-7A patent/BR112018072401A2/pt not_active Application Discontinuation
- 2017-06-08 EP EP17730438.3A patent/EP3468562A1/en not_active Withdrawn
- 2017-06-08 JP JP2018563848A patent/JP2019517542A/ja active Pending
- 2017-06-08 MX MX2018015089A patent/MX390363B/es unknown
- 2017-06-08 KR KR1020197000835A patent/KR102391564B1/ko active Active
- 2017-06-08 US US15/616,974 patent/US10155000B2/en active Active
- 2017-06-08 WO PCT/EP2017/064007 patent/WO2017211979A1/en not_active Ceased
- 2017-06-08 CN CN201780035691.0A patent/CN109310697A/zh active Pending
- 2017-06-08 EP EP23174651.2A patent/EP4233840A3/en active Pending
- 2017-06-08 CA CA3022202A patent/CA3022202A1/en active Pending
- 2017-06-08 AU AU2017276758A patent/AU2017276758A1/en not_active Abandoned
-
2018
- 2018-10-25 US US16/170,134 patent/US20190060320A1/en not_active Abandoned
- 2018-11-26 CL CL2018003361A patent/CL2018003361A1/es unknown
- 2018-12-10 PH PH12018502593A patent/PH12018502593A1/en unknown
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2020
- 2020-02-12 US US16/788,608 patent/US20200171038A1/en not_active Abandoned
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2021
- 2021-03-23 US US17/209,365 patent/US20210205315A1/en not_active Abandoned
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2022
- 2022-04-08 JP JP2022064467A patent/JP2022093381A/ja active Pending
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2023
- 2023-03-27 AU AU2023201872A patent/AU2023201872B2/en active Active
- 2023-08-07 US US18/230,693 patent/US12364700B2/en active Active
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2024
- 2024-06-17 JP JP2024097197A patent/JP2024127897A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US10155000B2 (en) | 2018-12-18 |
| EP3468562A1 (en) | 2019-04-17 |
| MX2018015089A (es) | 2019-05-13 |
| KR102391564B1 (ko) | 2022-04-29 |
| EP4233840A2 (en) | 2023-08-30 |
| US20230381188A1 (en) | 2023-11-30 |
| AU2017276758A1 (en) | 2018-11-08 |
| AU2023201872A1 (en) | 2023-05-04 |
| US20170354660A1 (en) | 2017-12-14 |
| KR20190017936A (ko) | 2019-02-20 |
| CN109310697A (zh) | 2019-02-05 |
| JP2024127897A (ja) | 2024-09-20 |
| CL2018003361A1 (es) | 2019-03-22 |
| US20190060320A1 (en) | 2019-02-28 |
| EP4233840A3 (en) | 2023-10-18 |
| NZ747331A (en) | 2025-06-27 |
| PH12018502593A1 (en) | 2019-10-14 |
| US20210205315A1 (en) | 2021-07-08 |
| MX390363B (es) | 2025-03-20 |
| WO2017211979A1 (en) | 2017-12-14 |
| JP2019517542A (ja) | 2019-06-24 |
| JP2022093381A (ja) | 2022-06-23 |
| BR112018072401A2 (pt) | 2019-02-19 |
| US20200171038A1 (en) | 2020-06-04 |
| AU2023201872B2 (en) | 2025-03-06 |
| US12364700B2 (en) | 2025-07-22 |
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