TW200522976A
(en)
*
|
2003-09-19 |
2005-07-16 |
Novo Nordisk As |
Novel plasma protein affinity tags
|
US7279457B2
(en)
*
|
2004-03-12 |
2007-10-09 |
Biodel, Inc. |
Rapid acting drug delivery compositions
|
US7878978B2
(en)
|
2004-03-18 |
2011-02-01 |
University Of Pittsburgh- Of The Commonwealth System Of Higher Education |
Use of relaxin to increase arterial compliance
|
EP1750756A2
(en)
|
2004-05-10 |
2007-02-14 |
Nastech Pharmaceutical Company Inc. |
Compositions and methods for enhanced mucosal delivery of parathyroid hormone
|
CA2569240A1
(en)
|
2004-06-01 |
2005-12-15 |
Domantis Limited |
Drug fusion comprising a polypeptide drug and an immunoglobulin heavy chain variable domain specific for serum albumin
|
WO2006005667A2
(en)
*
|
2004-07-08 |
2006-01-19 |
Novo Nordisk A/S |
Polypeptide protracting tags comprising a tetrazole moiety
|
EP1799710A2
(en)
|
2004-10-07 |
2007-06-27 |
Novo Nordisk A/S |
Protracted glp-1 compounds
|
US8030273B2
(en)
|
2004-10-07 |
2011-10-04 |
Novo Nordisk A/S |
Protracted exendin-4 compounds
|
US8394765B2
(en)
|
2004-11-01 |
2013-03-12 |
Amylin Pharmaceuticals Llc |
Methods of treating obesity with two different anti-obesity agents
|
CN101128487B
(zh)
|
2004-12-02 |
2012-10-10 |
杜门蒂斯有限公司 |
靶向血清白蛋白和glp-1或pyy的双特异性结构域抗体
|
TWI362392B
(en)
*
|
2005-03-18 |
2012-04-21 |
Novo Nordisk As |
Acylated glp-1 compounds
|
JP5755398B2
(ja)
|
2005-03-18 |
2015-07-29 |
ノヴォ ノルディスク アー/エス |
伸長されたglp−1化合物
|
EP2295452A1
(en)
|
2005-05-04 |
2011-03-16 |
Zealand Pharma A/S |
Glucagon-like-peptide-2 (GLP-2) analogues
|
CN101217940B
(zh)
*
|
2005-06-06 |
2013-03-27 |
卡穆鲁斯公司 |
Glp-1类似物制剂
|
CN100429227C
(zh)
*
|
2005-06-29 |
2008-10-29 |
常州制药厂有限公司 |
Exendin4多肽片段
|
US7846445B2
(en)
*
|
2005-09-27 |
2010-12-07 |
Amunix Operating, Inc. |
Methods for production of unstructured recombinant polymers and uses thereof
|
US7855279B2
(en)
*
|
2005-09-27 |
2010-12-21 |
Amunix Operating, Inc. |
Unstructured recombinant polymers and uses thereof
|
AU2006312307A1
(en)
*
|
2005-11-01 |
2007-05-18 |
Amylin Pharmaceuticals, Inc. |
Treatment of obesity and related disorders
|
WO2007056362A2
(en)
|
2005-11-07 |
2007-05-18 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting physiological solubility and stability
|
WO2007068718A1
(en)
|
2005-12-14 |
2007-06-21 |
Novo Nordisk A/S |
Polypeptide protracting tags
|
US8293869B2
(en)
|
2005-12-16 |
2012-10-23 |
Nektar Therapeutics |
Polymer conjugates of GLP-1
|
DK1987052T3
(da)
|
2006-02-08 |
2011-08-15 |
Lonza Ag |
Syntese af glucagonlignende peptider
|
JP5252435B2
(ja)
*
|
2006-03-15 |
2013-07-31 |
ノボ・ノルデイスク・エー/エス |
アミリン誘導体
|
EP2573111A1
(en)
*
|
2006-04-20 |
2013-03-27 |
Amgen Inc. |
GLP-1 compounds
|
RU2009108280A
(ru)
|
2006-08-08 |
2010-09-20 |
Санофи-Авентис (Fr) |
Ариламиноарилалкилзамещенные имидазолидин-2,4-дионы, способы их получения, содержащие эти соединения лекарственные средства и их применение
|
US20090318353A1
(en)
*
|
2006-08-25 |
2009-12-24 |
Novo Nordisk A/S |
Acylated Exendin-4 Compounds
|
EA023886B1
(ru)
|
2006-11-08 |
2016-07-29 |
Зеаланд Фарма А/С |
Селективные аналоги глюкагонподобного пептида-2 (glp-2)
|
JP2010043001A
(ja)
*
|
2006-11-09 |
2010-02-25 |
Sanwa Kagaku Kenkyusho Co Ltd |
Glp−1誘導体とその用途
|
MX2009006564A
(es)
*
|
2007-01-05 |
2009-06-26 |
Univ Indiana Res & Tech Corp |
Analogos de glucagon que muestran solubilidad potenciada en amortiguadores a ph fisiologico.
|
DE102007005045B4
(de)
|
2007-01-26 |
2008-12-18 |
Sanofi-Aventis |
Phenothiazin Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
KR20090119876A
(ko)
|
2007-02-15 |
2009-11-20 |
인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 |
글루카곤/glp-1 수용체 공동-항진물질
|
AU2008275911A1
(en)
*
|
2007-07-19 |
2009-01-22 |
Arizona Board of Regents, a body corporate acting for and on behalf of Arizona State University |
Self- anchoring MEMS intrafascicular neural electrode
|
KR20100058541A
(ko)
*
|
2007-08-15 |
2010-06-03 |
아뮤닉스 인코포레이티드 |
생물학적 활성 폴리펩티드의 특성을 변경하기 위한 조성물 및 방법
|
EP2025674A1
(de)
|
2007-08-15 |
2009-02-18 |
sanofi-aventis |
Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
EP2190873B1
(en)
|
2007-09-05 |
2015-07-22 |
Novo Nordisk A/S |
Truncated glp-1 derivatives and their therapeutical use
|
EP2190460B1
(en)
*
|
2007-09-05 |
2014-12-17 |
Novo Nordisk A/S |
Peptides derivatized with a-b-c-d- and their therapeutical use
|
EP2679597A1
(en)
|
2007-09-05 |
2014-01-01 |
Novo Nordisk A/S |
Glucagon-like peptide-1 derivatives and their pharmaceutical use
|
EP2036923A1
(en)
*
|
2007-09-11 |
2009-03-18 |
Novo Nordisk A/S |
Improved derivates of amylin
|
ES2558155T3
(es)
*
|
2007-10-30 |
2016-02-02 |
Indiana University Research And Technology Corporation |
Compuestos que muestran actividad antagonista de glucacón y agonista de GLP-1
|
US8981047B2
(en)
|
2007-10-30 |
2015-03-17 |
Indiana University Research And Technology Corporation |
Glucagon antagonists
|
DE102007054497B3
(de)
|
2007-11-13 |
2009-07-23 |
Sanofi-Aventis Deutschland Gmbh |
Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung
|
KR101616995B1
(ko)
*
|
2007-12-03 |
2016-06-07 |
(주)아모레퍼시픽 |
슬리밍용 조성물
|
US20100317057A1
(en)
|
2007-12-28 |
2010-12-16 |
Novo Nordisk A/S |
Semi-recombinant preparation of glp-1 analogues
|
AU2009204309B2
(en)
*
|
2008-01-04 |
2012-11-22 |
Biodel, Inc. |
Insulin formulations for insulin release as a function of tissue glucose levels
|
CN101983066B
(zh)
*
|
2008-01-30 |
2016-06-29 |
印第安那大学科技研究公司 |
基于酯的胰岛素前药
|
EP2910571B1
(en)
|
2008-03-18 |
2016-10-05 |
Novo Nordisk A/S |
Protease stabilized, acylated insulin analogues
|
CN101977624A
(zh)
*
|
2008-03-20 |
2011-02-16 |
欧加农股份有限公司 |
用于增加骨矿物质密度的药物组合物的制备
|
AU2009231439A1
(en)
|
2008-03-31 |
2009-10-08 |
Glaxo Group Limited |
Drug fusions and conjugates
|
KR20110017874A
(ko)
*
|
2008-05-16 |
2011-02-22 |
노보 노르디스크 에이/에스 |
오래 작용하는 y2 및/또는 y4 수용체 작용제
|
PA8830501A1
(es)
|
2008-06-17 |
2010-07-27 |
Univ Indiana Res & Tech Corp |
Co-agonistas del receptor de glucagon/glp-1
|
SG192405A1
(en)
*
|
2008-06-17 |
2013-08-30 |
Univ Indiana Res & Tech Corp |
Gip-based mixed agonists for treatment of metabolic disorders and obesity
|
WO2009155257A1
(en)
*
|
2008-06-17 |
2009-12-23 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting enhanced solubility and stability physiological ph buffers
|
WO2010003624A2
(en)
|
2008-07-09 |
2010-01-14 |
Sanofi-Aventis |
Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
|
CN102112157B
(zh)
*
|
2008-08-06 |
2013-05-29 |
诺沃-诺迪斯克保健股份有限公司 |
具有延长的体内效能的缀合蛋白
|
EP2340261B1
(en)
|
2008-10-21 |
2017-12-20 |
Novo Nordisk A/S |
Amylin derivatives
|
AU2009324037B2
(en)
|
2008-12-05 |
2015-07-30 |
Glaxo Group Limited |
Methods for selecting protease resistant polypeptides
|
WO2010068601A1
(en)
|
2008-12-08 |
2010-06-17 |
Sanofi-Aventis |
A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
|
CN102300580A
(zh)
*
|
2008-12-19 |
2011-12-28 |
印第安纳大学研究及科技有限公司 |
二肽连接的药剂
|
AU2009335715B2
(en)
|
2008-12-19 |
2016-09-15 |
Indiana University Research And Technology Corporation |
Amide-based insulin prodrugs
|
JP2012512903A
(ja)
|
2008-12-19 |
2012-06-07 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーション |
アミド系グルカゴンスーパーファミリーペプチドプロドラッグ
|
TWI504405B
(zh)
|
2009-01-22 |
2015-10-21 |
Novo Nordisk Healthcare Ag |
穩定的生長激素化合物
|
ES2692495T3
(es)
*
|
2009-01-23 |
2018-12-03 |
Novo Nordisk A/S |
Derivados del FGF21 con aglutinante de albúmina A-B-C-D-E- y sus usos
|
US8680050B2
(en)
*
|
2009-02-03 |
2014-03-25 |
Amunix Operating Inc. |
Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same
|
CN116925238A
(zh)
|
2009-02-03 |
2023-10-24 |
阿穆尼克斯制药公司 |
延伸重组多肽和包含该延伸重组多肽的组合物
|
US8703717B2
(en)
*
|
2009-02-03 |
2014-04-22 |
Amunix Operating Inc. |
Growth hormone polypeptides and methods of making and using same
|
US9060927B2
(en)
*
|
2009-03-03 |
2015-06-23 |
Biodel Inc. |
Insulin formulations for rapid uptake
|
MX2011010151A
(es)
|
2009-03-27 |
2011-12-14 |
Glaxo Group Ltd |
Fusiones y conjugados de farmaco.
|
CA2764108A1
(en)
|
2009-06-08 |
2010-12-16 |
Amunix Operating Inc. |
Glucose-regulating polypeptides and methods of making and using same
|
US9849188B2
(en)
|
2009-06-08 |
2017-12-26 |
Amunix Operating Inc. |
Growth hormone polypeptides and methods of making and using same
|
SG176858A1
(en)
|
2009-06-16 |
2012-02-28 |
Univ Indiana Res & Tech Corp |
Gip receptor-active glucagon compounds
|
WO2011015649A1
(en)
|
2009-08-06 |
2011-02-10 |
Novo Nordisk Health Care Ag |
Growth hormones with prolonged in-vivo efficacy
|
CN102741422B
(zh)
*
|
2009-08-24 |
2016-06-08 |
阿穆尼克斯运营公司 |
凝血因子ⅶ组合物及其制备和使用方法
|
WO2011023754A1
(en)
|
2009-08-26 |
2011-03-03 |
Sanofi-Aventis |
Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use
|
CN102573888A
(zh)
*
|
2009-09-18 |
2012-07-11 |
诺和诺德公司 |
长效y2 受体激动剂
|
CN104147611A
(zh)
|
2009-09-30 |
2014-11-19 |
葛兰素集团有限公司 |
具有延长的半衰期的药物融合体和缀合物
|
WO2011051312A1
(en)
|
2009-10-30 |
2011-05-05 |
Novo Nordisk A/S |
Derivatives of cgrp
|
WO2011058165A1
(en)
*
|
2009-11-13 |
2011-05-19 |
Novo Nordisk A/S |
Long-acting y2 receptor agonists
|
CA2784757A1
(en)
|
2009-12-16 |
2011-07-07 |
Novo Nordisk A/S |
Double-acylated glp-1 derivatives
|
US8703701B2
(en)
|
2009-12-18 |
2014-04-22 |
Indiana University Research And Technology Corporation |
Glucagon/GLP-1 receptor co-agonists
|
AU2011208620B2
(en)
|
2010-01-22 |
2015-04-16 |
Novo Nordisk Health Care Ag |
Stable growth hormone compounds
|
BR112012018116B1
(pt)
*
|
2010-01-22 |
2022-06-21 |
Novo Nordisk Health Care Ag |
Conjugados de hormônio do crescimento com eficácia in vivo prolongada
|
EP2528618A4
(en)
|
2010-01-27 |
2015-05-27 |
Univ Indiana Res & Tech Corp |
GLUCAGON ANTAGONISTE AND GIP AGONISTS CONJUGATES AND COMPOSITIONS FOR THE TREATMENT OF METABOLISM DISEASES AND ADIPOSITAS
|
WO2011101261A2
(en)
*
|
2010-02-16 |
2011-08-25 |
Novo Nordisk A/S |
Purification method
|
WO2011107494A1
(de)
|
2010-03-03 |
2011-09-09 |
Sanofi |
Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
WO2011109787A1
(en)
*
|
2010-03-05 |
2011-09-09 |
Conjuchem, Llc |
Methods of administering insulinotropic peptides
|
RU2559320C2
(ru)
*
|
2010-03-26 |
2015-08-10 |
Ново Нордиск А/С |
Новые аналоги глюкагона
|
US8557961B2
(en)
|
2010-04-02 |
2013-10-15 |
Amunix Operating Inc. |
Alpha 1-antitrypsin compositions and methods of making and using same
|
DE102010015123A1
(de)
|
2010-04-16 |
2011-10-20 |
Sanofi-Aventis Deutschland Gmbh |
Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
|
US9040660B2
(en)
|
2010-04-20 |
2015-05-26 |
Novo Nordisk A/S |
Long-acting gastrin derivatives
|
WO2011134284A1
(zh)
*
|
2010-04-27 |
2011-11-03 |
浙江贝达药业有限公司 |
胰高血糖素样肽-1类似物及其应用
|
US20130123460A1
(en)
|
2010-04-30 |
2013-05-16 |
Sanwa Kagaku Kenkyusho Co., Ltd. |
Peptide for improving biostability of bioactive substance, and bioactive substance having improved biostability
|
EP2569000B1
(en)
|
2010-05-13 |
2017-09-27 |
Indiana University Research and Technology Corporation |
Glucagon superfamily peptides exhibiting nuclear hormone receptor activity
|
CA2797089A1
(en)
|
2010-05-13 |
2011-11-17 |
Indiana University Research And Technology Corporation |
Glucagon superfamily peptides exhibiting g protein-coupled receptor activity
|
CN103068842B
(zh)
|
2010-06-16 |
2016-10-19 |
印第安纳大学研究及科技有限公司 |
对胰岛素受体具有高活性的单链胰岛素激动剂
|
EP2582709B1
(de)
|
2010-06-18 |
2018-01-24 |
Sanofi |
Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
|
US8530413B2
(en)
|
2010-06-21 |
2013-09-10 |
Sanofi |
Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
|
EP2585102B1
(en)
|
2010-06-24 |
2015-05-06 |
Indiana University Research and Technology Corporation |
Amide-based insulin prodrugs
|
MX2012014576A
(es)
|
2010-06-24 |
2013-02-21 |
Univ Indiana Res & Tech Corp |
Profarmacos de peptido de la superfamilia de glucagon basado en amida.
|
TW201215388A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Sa |
(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
|
TW201215387A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Aventis |
Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
CN103415300B
(zh)
*
|
2010-07-20 |
2018-02-23 |
诺沃—诺迪斯克有限公司 |
N‑末端修饰的fgf21化合物
|
ES2641869T3
(es)
|
2010-09-28 |
2017-11-14 |
Aegerion Pharmaceuticals, Inc. |
Polipéptidos de fusión de leptina-ABD con duración de acción aumentada
|
WO2012062803A1
(en)
|
2010-11-09 |
2012-05-18 |
Novo Nordisk A/S |
Double-acylated glp-1 derivatives
|
BR112013014942B1
(pt)
|
2010-12-16 |
2020-01-28 |
Novo Nordisk As |
composições sólidas para administração, e seus usos
|
MA34885B1
(fr)
|
2010-12-22 |
2014-02-01 |
Indiana Unversity Res And Technology Corp |
Analogues du glucagon presentant una ctivite de recepteur de gip
|
BR112013018628A2
(pt)
*
|
2011-01-26 |
2017-07-18 |
Novo Nordisk As |
derivados da leptina
|
US8871758B2
(en)
|
2011-03-08 |
2014-10-28 |
Sanofi |
Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
|
EP2683704B1
(de)
|
2011-03-08 |
2014-12-17 |
Sanofi |
Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
EP2683699B1
(de)
|
2011-03-08 |
2015-06-24 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
WO2012120054A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
WO2012120051A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
US8901114B2
(en)
|
2011-03-08 |
2014-12-02 |
Sanofi |
Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
|
US8895547B2
(en)
|
2011-03-08 |
2014-11-25 |
Sanofi |
Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
|
EP2683702B1
(de)
|
2011-03-08 |
2014-12-24 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
EP2683701B1
(de)
|
2011-03-08 |
2014-12-24 |
Sanofi |
Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
JP5871905B2
(ja)
|
2011-03-30 |
2016-03-01 |
ベータ ファーマシューティカルズ カンパニー リミテッド |
グルカゴン様ペプチド−1類似体およびその使用
|
WO2012136792A2
(en)
|
2011-04-07 |
2012-10-11 |
Glaxo Group Limited |
Cck compositions
|
WO2012136790A1
(en)
|
2011-04-07 |
2012-10-11 |
Glaxo Group Limited |
Compositions comprising fusion proteins or conjugates with an improved half -life
|
WO2012140647A2
(en)
|
2011-04-11 |
2012-10-18 |
Yeda Research And Development Co. Ltd |
Albumin binding probes and drug conjugates thereof
|
ES2612278T3
(es)
|
2011-04-12 |
2017-05-16 |
Novo Nordisk A/S |
Derivados de GLP-1 doble-acilados
|
US9320777B2
(en)
|
2011-05-13 |
2016-04-26 |
Bolder Biotechnology, Inc. |
Methods and use of growth hormone supergene family protein analogs for treatment of radiation exposure
|
US9156902B2
(en)
|
2011-06-22 |
2015-10-13 |
Indiana University Research And Technology Corporation |
Glucagon/GLP-1 receptor co-agonists
|
BR112013032717A2
(pt)
|
2011-06-22 |
2017-01-24 |
Univ Indiana Res & Tech Corp |
coagonistas do receptor de glucagon/glp-1
|
EP2729481B1
(en)
*
|
2011-07-08 |
2018-10-17 |
Amylin Pharmaceuticals, LLC |
Engineered polypeptides having enhanced duration of action with reduced immunogenicity
|
CN103957926B
(zh)
|
2011-07-08 |
2018-07-03 |
安米林药品有限责任公司 |
具有增强的作用持续时间和降低的免疫原性的工程改造的多肽
|
WO2013037390A1
(en)
|
2011-09-12 |
2013-03-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
EP2567959B1
(en)
|
2011-09-12 |
2014-04-16 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
KR20140070612A
(ko)
|
2011-09-23 |
2014-06-10 |
노보 노르디스크 에이/에스 |
신규 글루카곤 유사체
|
WO2013045413A1
(en)
|
2011-09-27 |
2013-04-04 |
Sanofi |
6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
CA2847246A1
(en)
|
2011-11-17 |
2013-05-23 |
Indiana University Research And Technology Corporation |
Glucagon superfamily peptides exhibiting glucocorticoid receptor activity
|
JP2015500823A
(ja)
|
2011-12-09 |
2015-01-08 |
ノヴォ ノルディスク アー/エス |
Glp−1アゴニスト
|
CN104114183A
(zh)
|
2011-12-20 |
2014-10-22 |
印第安纳大学研究及科技有限公司 |
用于治疗糖尿病的基于ctp的胰岛素类似物
|
WO2013096939A1
(en)
*
|
2011-12-23 |
2013-06-27 |
Sri International |
Selective binding compounds
|
CA2861000A1
(en)
|
2011-12-29 |
2013-07-04 |
Novo Nordisk A/S |
Dipeptide comprising a non-proteogenic amino acid
|
JP6383666B2
(ja)
|
2012-02-15 |
2018-08-29 |
バイオベラティブ セラピューティクス インコーポレイテッド |
組換え第viii因子タンパク質
|
JP6256882B2
(ja)
|
2012-02-15 |
2018-01-10 |
アムニクス オペレーティング インコーポレイテッド |
第viii因子組成物、ならびに組成物の作製方法および用途
|
WO2013130684A1
(en)
|
2012-02-27 |
2013-09-06 |
Amunix Operating Inc. |
Xten-folate conjugate compositions and methods of making same
|
KR102072202B1
(ko)
|
2012-03-22 |
2020-01-31 |
노보 노르디스크 에이/에스 |
Glp-1 펩티드의 조성물 및 그것의 제조
|
WO2013139695A1
(en)
|
2012-03-22 |
2013-09-26 |
Novo Nordisk A/S |
Compositions comprising a delivery agent and preparation thereof
|
HUE042757T2
(hu)
|
2012-03-22 |
2019-07-29 |
Novo Nordisk As |
Szállító szert tartalmazó készítmények és elõállításuk
|
TR201802689T4
(tr)
|
2012-05-03 |
2018-03-21 |
Zealand Pharma As |
Glukagon benzeri peptit-2 (glp-2) analogları.
|
US10000542B2
(en)
|
2012-05-08 |
2018-06-19 |
Novo Nordisk A/S |
Double-acylated GLP-1 derivatives
|
US11274135B2
(en)
|
2012-05-08 |
2022-03-15 |
Novo Nordisk A/S |
Double-acylated GLP-1 derivatives
|
EP2849775A1
(en)
|
2012-05-16 |
2015-03-25 |
Glaxo Group Limited |
Polypeptide loaded poca nanoparticles for oral administration
|
ES2871328T3
(es)
|
2012-06-20 |
2021-10-28 |
Novo Nordisk As |
Formulación de comprimido que comprende un péptido y un agente de suministro
|
CA2877358A1
(en)
|
2012-06-21 |
2013-12-27 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting gip receptor activity
|
AU2013286177B2
(en)
|
2012-07-01 |
2018-04-26 |
Novo Nordisk A/S |
Use of long-acting GLP-1 peptides
|
JP6387008B2
(ja)
|
2012-09-26 |
2018-09-05 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
インスリンアナローグダイマー
|
CN104717972A
(zh)
|
2012-10-17 |
2015-06-17 |
诺和诺德A/S(股份有限公司) |
用于口服肽递送的脂肪酸酰化氨基酸
|
EP2911655A1
(en)
|
2012-10-24 |
2015-09-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Tpl2 kinase inhibitors for preventing or treating diabetes and for promoting -cell survival
|
WO2014158900A1
(en)
|
2013-03-14 |
2014-10-02 |
Indiana University Research And Technology Corporation |
Insulin-incretin conjugates
|
CN103217522A
(zh)
*
|
2013-03-18 |
2013-07-24 |
中国人民解放军第四军医大学 |
一种采用消化法消化提取细胞流式检测组织内细胞凋亡率的方法
|
WO2014166836A1
(en)
|
2013-04-05 |
2014-10-16 |
Novo Nordisk A/S |
Growth hormone compound formulation
|
WO2014170496A1
(en)
|
2013-04-18 |
2014-10-23 |
Novo Nordisk A/S |
Stable, protracted glp-1/glucagon receptor co-agonists for medical use
|
JP6475233B2
(ja)
*
|
2013-06-20 |
2019-02-27 |
ノヴォ ノルディスク アー/エス |
Glp−1誘導体及びその使用
|
EP3013370A1
(en)
*
|
2013-06-24 |
2016-05-04 |
Riogin Corporation |
Double binding constructs
|
US10548953B2
(en)
|
2013-08-14 |
2020-02-04 |
Bioverativ Therapeutics Inc. |
Factor VIII-XTEN fusions and uses thereof
|
JP6599863B2
(ja)
|
2013-08-15 |
2019-10-30 |
ノヴォ ノルディスク アー/エス |
Glp−1誘導体及びその使用
|
WO2015038938A1
(en)
|
2013-09-13 |
2015-03-19 |
The California Institute For Biomedical Research |
Modified therapeutic agents and compositions thereof
|
JP6499184B2
(ja)
|
2013-10-07 |
2019-04-10 |
ノヴォ ノルディスク アー/エス |
インスリン類似体の新規な誘導体
|
EP3068438A1
(en)
*
|
2013-11-11 |
2016-09-21 |
Ascendis Pharma Relaxin Division A/S |
Relaxin prodrugs
|
WO2015071356A1
(en)
|
2013-11-15 |
2015-05-21 |
Novo Nordisk A/S |
Hpyy(1 -36) having a beta-homoarginine substitution at position 35
|
MX369818B
(es)
|
2013-11-15 |
2019-11-22 |
Novo Nordisk As |
Compuestos selectivos de peptido yy (pyy) y usos de los mismos.
|
EP4212180A1
(en)
|
2013-12-18 |
2023-07-19 |
The Scripps Research Institute |
Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof
|
CN103985909B
(zh)
*
|
2014-05-14 |
2016-08-24 |
山东爱通工业机器人科技有限公司 |
一种锂电池电池片组左右两侧面贴胶装置
|
US10570184B2
(en)
|
2014-06-04 |
2020-02-25 |
Novo Nordisk A/S |
GLP-1/glucagon receptor co-agonists for medical use
|
US10588980B2
(en)
|
2014-06-23 |
2020-03-17 |
Novartis Ag |
Fatty acids and their use in conjugation to biomolecules
|
JP6701208B2
(ja)
|
2014-09-24 |
2020-05-27 |
インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション |
脂質化アミド系インスリンプロドラッグ
|
CN108271356A
(zh)
|
2014-09-24 |
2018-07-10 |
印第安纳大学研究及科技有限公司 |
肠降血糖素-胰岛素缀合物
|
ES2630106T3
(es)
|
2014-10-07 |
2017-08-18 |
Cyprumed Gmbh |
Formulaciones farmacéuticas para la administración oral de fármacos peptídicos o proteicos
|
WO2016065042A1
(en)
|
2014-10-22 |
2016-04-28 |
Extend Biosciences, Inc. |
Therapeutic vitamin d conjugates
|
SI3220892T1
(sl)
|
2014-11-21 |
2022-01-31 |
Ascendis Pharma Endocrinology Division A/S |
Oblike odmerjanja dolgotrajno delujočega rastnega hormona
|
JP6730278B2
(ja)
*
|
2014-11-27 |
2020-07-29 |
ノヴォ ノルディスク アー/エス |
Glp−1誘導体及びその使用
|
CN107108714B
(zh)
|
2014-12-17 |
2022-02-08 |
诺和诺德股份有限公司 |
Glp-1衍生物及其用途
|
RS59154B1
(sr)
|
2014-12-23 |
2019-10-31 |
Novo Nordisk As |
Fgf21 derivati i njihova upotreba
|
US9750785B2
(en)
|
2015-01-30 |
2017-09-05 |
Par Pharmaceutical, Inc. |
Vasopressin formulations for use in treatment of hypotension
|
US9375478B1
(en)
|
2015-01-30 |
2016-06-28 |
Par Pharmaceutical, Inc. |
Vasopressin formulations for use in treatment of hypotension
|
US9925233B2
(en)
|
2015-01-30 |
2018-03-27 |
Par Pharmaceutical, Inc. |
Vasopressin formulations for use in treatment of hypotension
|
US9744209B2
(en)
|
2015-01-30 |
2017-08-29 |
Par Pharmaceutical, Inc. |
Vasopressin formulations for use in treatment of hypotension
|
US9937223B2
(en)
|
2015-01-30 |
2018-04-10 |
Par Pharmaceutical, Inc. |
Vasopressin formulations for use in treatment of hypotension
|
US9687526B2
(en)
|
2015-01-30 |
2017-06-27 |
Par Pharmaceutical, Inc. |
Vasopressin formulations for use in treatment of hypotension
|
ES2805743T3
(es)
|
2015-03-24 |
2021-02-15 |
Inst Nat Sante Rech Med |
Método y composición farmacéutica para uso en el tratamiento de la diabetes
|
AU2016275735B2
(en)
|
2015-06-12 |
2020-02-06 |
Novo Nordisk A/S |
Selective PYY compounds and uses thereof
|
BR112018002150A2
(pt)
|
2015-08-03 |
2018-09-18 |
Bioverativ Therapeutics Inc |
proteínas de fusão do fator ix e métodos de fabricação e uso das mesmas
|
MX2018002226A
(es)
|
2015-08-28 |
2018-03-23 |
Amunix Operating Inc |
Ensamble de polipeptido quimerico y metodos para hacer y usar el mismo.
|
US11229683B2
(en)
|
2015-09-18 |
2022-01-25 |
Bolder Biotechnology, Inc. |
Hematopoietic growth factor proteins and analogs thereof and angiotensin converting enzyme inhibitors for treatment of radiation exposure
|
EP3353159A4
(en)
|
2015-09-22 |
2019-03-27 |
The Regents of The University of California |
Modified cytotoxins and their therapeutic use
|
US10286079B2
(en)
|
2015-09-22 |
2019-05-14 |
The Regents Of The University Of California |
Modified cytotoxins and their therapeutic use
|
CN108135962A
(zh)
|
2015-10-07 |
2018-06-08 |
塞浦路迈德有限责任公司 |
用于口服递送肽类药物的药物制剂
|
WO2017083604A1
(en)
*
|
2015-11-12 |
2017-05-18 |
Amgen Inc. |
Triazine mediated pharmacokinetic enhancement of therapeutics
|
US20190000923A1
(en)
|
2015-12-22 |
2019-01-03 |
Novartis Ag |
Methods of treating or ameliorating metabolic disorders using growth differentiation factor 15 (gdf-15)
|
SG11201806092TA
(en)
|
2016-03-01 |
2018-08-30 |
Ascendis Pharma Bone Diseases As |
Pth prodrugs
|
EP3484523A1
(en)
|
2016-07-13 |
2019-05-22 |
Ascendis Pharma A/S |
Conjugation method for carrier-linked prodrugs
|
SG10202111952PA
(en)
|
2016-09-29 |
2021-12-30 |
Ascendis Pharma Growth Disorders As |
Combination therapy with controlled-release cnp agonists
|
KR102611820B1
(ko)
|
2016-09-29 |
2023-12-07 |
아센디스 파마 본 디지즈 에이/에스 |
낮은 피크 대 트로프 비를 가진 pth 화합물
|
MA46428A
(fr)
|
2016-09-29 |
2019-08-07 |
Ascendis Pharma Bone Diseases As |
Schéma posologique incrémentiel dans des composés de pth à libération contrôlée
|
US11590207B2
(en)
|
2016-09-29 |
2023-02-28 |
Ascendis Pharma Bone Diseases A/S |
Dosage regimen for a controlled-release PTH compound
|
WO2018065634A1
(en)
|
2016-10-07 |
2018-04-12 |
Cyprumed Gmbh |
Pharmaceutical compositions for the nasal delivery of peptide or protein drugs
|
US10913952B2
(en)
*
|
2016-10-26 |
2021-02-09 |
Salk Institute For Biological Studies |
Environmental stress response transcriptional regulatory network
|
BR112019010624A2
(pt)
|
2016-12-09 |
2019-10-22 |
Zealand Pharma As |
agonistas duplos de glp-1/glp-2 acilados e composição
|
TWI700092B
(zh)
|
2016-12-16 |
2020-08-01 |
丹麥商諾佛.儂迪克股份有限公司 |
含胰島素醫藥組成物
|
PE20211202A1
(es)
|
2017-08-24 |
2021-07-05 |
Novo Nordisk As |
Composiciones de glp-1 y sus usos
|
PL3746111T3
(pl)
|
2018-02-02 |
2024-01-15 |
Novo Nordisk A/S |
Stałe kompozycje zawierające agonistę glp-1 i sól kwasu n-(8-(2- hydroksybenzoilo)amino kaprylowego i substancję poślizgową
|
US20200405820A1
(en)
*
|
2018-03-16 |
2020-12-31 |
The General Hospital Corporation |
Parathyroid hormone polypeptide conjugates and methods of their use
|
MX2020009950A
(es)
*
|
2018-03-23 |
2021-04-28 |
Carmot Therapeutics Inc |
Moduladores de receptores acoplados a proteina g.
|
AU2019246390A1
(en)
|
2018-03-28 |
2020-08-06 |
Ascendis Pharma A/S |
Conjugates
|
JP2021519336A
(ja)
|
2018-03-28 |
2021-08-10 |
アセンディス ファーマ オンコロジー ディヴィジョン エー/エス |
Il−2コンジュゲート
|
PL3774862T3
(pl)
|
2018-04-05 |
2022-10-03 |
Sun Pharmaceutical Industries Limited |
Nowe analogi glp-1
|
JP7442823B2
(ja)
|
2018-04-06 |
2024-03-05 |
シプルメット・ゲーエムベーハー |
治療用ペプチド及び治療用タンパク質の経粘膜送達のための薬学的組成物
|
TWI829687B
(zh)
|
2018-05-07 |
2024-01-21 |
丹麥商諾佛 儂迪克股份有限公司 |
包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物
|
MX2020012179A
(es)
|
2018-05-18 |
2021-01-29 |
Ascendis Pharma Bone Diseases As |
Dosis inicial de conjugados de hormona paratiroidea (pth).
|
CN116920081A
(zh)
*
|
2018-05-31 |
2023-10-24 |
香港理工大学 |
用于癌症、肥胖症、代谢紊乱和相关并发症及合并症的精氨酸耗竭剂的组合物和应用
|
AU2019277029C1
(en)
|
2018-06-01 |
2024-01-04 |
Novartis Ag |
Binding molecules against BCMA and uses thereof
|
JP2022513626A
(ja)
|
2018-11-26 |
2022-02-09 |
ノバルティス アーゲー |
Lpl-gpihbp1融合ポリペプチド
|
EP3914282A1
(en)
|
2019-01-25 |
2021-12-01 |
Ospedale San Raffaele S.r.l. |
Inhibitor of dux4 and uses thereof
|
WO2020165087A1
(en)
|
2019-02-11 |
2020-08-20 |
Ascendis Pharma Bone Diseases A/S |
Liquid pharmaceutical formulations of pth conjugates
|
WO2020178273A1
(en)
|
2019-03-04 |
2020-09-10 |
Ascendis Pharma Endocrinology Division A/S |
Long-acting growth hormone dosage forms with superior efficacy to daily somatropin
|
TW202100559A
(zh)
|
2019-05-21 |
2021-01-01 |
瑞士商諾華公司 |
Cd19 結合分子及其用途
|
US20230071196A1
(en)
|
2019-05-21 |
2023-03-09 |
Novartis Ag |
Variant cd58 domains and uses thereof
|
CN116925237A
(zh)
|
2019-12-31 |
2023-10-24 |
北京质肽生物医药科技有限公司 |
Glp-1和gdf15的融合蛋白以及其缀合物
|
JP2023510790A
(ja)
|
2020-01-13 |
2023-03-15 |
アセンディス ファーマ ボーン ディジージズ エー/エス |
副甲状腺機能低下症の治療
|
PE20221575A1
(es)
|
2020-02-18 |
2022-10-06 |
Novo Nordisk As |
Formulaciones farmaceuticas
|
US20230165939A1
(en)
|
2020-04-29 |
2023-06-01 |
Novo Nordisk A/S |
Solid compositions comprising a glp-1 agonist and histidine
|
JP2023527919A
(ja)
|
2020-06-03 |
2023-06-30 |
アセンディス ファーマ オンコロジー ディヴィジョン エー/エス |
Il-2配列及びその使用
|
BR112023003476A2
(pt)
|
2020-08-28 |
2023-04-11 |
Ascendis Pharma Oncology Div A/S |
Proteínas il-2 glicosiladas e usos das mesmas
|
EP4210680A1
(en)
|
2020-09-07 |
2023-07-19 |
Cyprumed GmbH |
Improved pharmaceutical formulations of glp-1 receptor agonists
|
EP4217004A1
(en)
|
2020-09-28 |
2023-08-02 |
Ascendis Pharma Bone Diseases A/S |
Improvement of physical and mental well-being of patients with hypoparathyroidism
|
CN115925994B
(zh)
*
|
2020-09-30 |
2023-09-22 |
北京质肽生物医药科技有限公司 |
多肽缀合物和使用方法
|
WO2022097060A1
(en)
|
2020-11-06 |
2022-05-12 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
CN116710462A
(zh)
|
2021-01-20 |
2023-09-05 |
维京治疗公司 |
用于治疗代谢病症和肝病的组合物和方法
|
AU2022246997A1
(en)
|
2021-04-01 |
2023-09-28 |
Ascendis Pharma A/S |
Use of long-acting growth hormone for treating inflammation-induced diseases
|
EP4360645A1
(en)
*
|
2021-06-25 |
2024-05-01 |
Gan & Lee Pharmaceuticals Co., Ltd. |
Pharmaceutical composition containing glp-1 compound
|
WO2023012263A1
(en)
|
2021-08-04 |
2023-02-09 |
Novo Nordisk A/S |
Solid oral peptide formulations
|
CA3230895A1
(en)
|
2021-09-22 |
2023-03-30 |
Kennett Sprogoe |
Long-acting pth compound treatments
|