GB9818730D0
(en)
*
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collections of compounds
|
GB9818731D0
(en)
*
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Compounds
|
GB9818732D0
(en)
*
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collection of compounds
|
PT1413582E
(pt)
|
1998-08-27 |
2006-07-31 |
Spirogen Ltd |
Pirrolobenzodiazepinas dimericas
|
GB0226593D0
(en)
*
|
2002-11-14 |
2002-12-24 |
Consultants Ltd |
Compounds
|
CA2520898C
(en)
*
|
2003-03-31 |
2009-10-20 |
Council Of Scientific And Industrial Research |
Non-cross-linking pyrrolo(2,1-c)(1,4)benzodiazepines as potential antitumour agents and process thereof
|
GB0321295D0
(en)
*
|
2003-09-11 |
2003-10-15 |
Spirogen Ltd |
Synthesis of protected pyrrolobenzodiazepines
|
GB0416511D0
(en)
*
|
2003-10-22 |
2004-08-25 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
WO2005040170A2
(en)
*
|
2003-10-22 |
2005-05-06 |
Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Pyrrolobenzodiazepine derivatives, compositions comprising the same and methods related thereto
|
JPWO2005040172A1
(ja)
*
|
2003-10-29 |
2007-03-08 |
協和醗酵工業株式会社 |
三環性プロリン誘導体
|
WO2005063759A1
(en)
*
|
2003-12-31 |
2005-07-14 |
Council Of Scientific And Industrial Research |
PROCESS FOR PREPARING PYRROLO[2, 1-c] [1, 4] BENZODIAZEPINE HYBRIDS
|
GB2424884B
(en)
*
|
2003-12-31 |
2008-06-11 |
Council Scient Ind Res |
C-8 linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids
|
GB0404574D0
(en)
*
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Amino acids
|
PT2270010E
(pt)
*
|
2004-03-01 |
2012-03-12 |
Spirogen Ltd |
Derivados de 11-hidroxi-5h-pirrolo[2,1-c][1,4]benzodiazepin- 5-ona como intermediários chave para a preparação de pirrolobenzodiazepinas substituídas em c2
|
GB0404577D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
GB0404578D0
(en)
*
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
EP1723152B1
(en)
*
|
2004-03-09 |
2015-02-11 |
Spirogen Sàrl |
Pyrrolobenzodiazepines
|
US6951853B1
(en)
|
2004-03-30 |
2005-10-04 |
Council Of Scientific And Industrial Research |
Process for preparing pyrrolo[2, 1-c] [1,4] benzodiazepine hybrids
|
US7056913B2
(en)
|
2004-03-30 |
2006-06-06 |
Council Of Scientific And Industrial Research |
C8—linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids
|
FR2869231B1
(fr)
*
|
2004-04-27 |
2008-03-14 |
Sod Conseils Rech Applic |
Composition therapeutique contenant au moins un derive de la pyrrolobenzodiazepine et la fludarabine
|
GB0410725D0
(en)
*
|
2004-05-13 |
2004-06-16 |
Spirogen Ltd |
Pyrrolobenzodiazepine therapeutic agents
|
GB0508084D0
(en)
*
|
2005-04-21 |
2005-06-01 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
WO2006111759A1
(en)
*
|
2005-04-21 |
2006-10-26 |
Spirogen Limited |
Pyrrolobenzodiazepines
|
ATE427949T1
(de)
*
|
2005-10-05 |
2009-04-15 |
Spirogen Ltd |
4-a4-(5-oxo-2,3,5,11a-tetrahydro-5h-pyrrolo a2, 1-cua1,4ubenzodiazepin-8-yloxy)-butyrylaminou-1 - pyrrol-2-carbonsaurealkylesterderivate und verwandte verbindung zur behandlung einer proliferativen erkrankung
|
PT1813614E
(pt)
|
2006-01-25 |
2012-01-09 |
Sanofi Sa |
Agentes citotóxicos compreendendo novos derivados de tomaimicina
|
DE102006013678A1
(de)
*
|
2006-03-24 |
2007-09-27 |
Bayerische Motoren Werke Ag |
Gleit- oder Schmiermittel und Verfahren zum Aufziehen eines Fahrzeugreifens auf eine Felge
|
ZA200900545B
(en)
|
2006-07-18 |
2010-03-31 |
Sanofi Aventis |
Antagonist antibody against EPHA2 for the treatment of cancer
|
GB0619325D0
(en)
|
2006-09-30 |
2006-11-08 |
Univ Strathclyde |
New compounds
|
EP1914242A1
(en)
|
2006-10-19 |
2008-04-23 |
Sanofi-Aventis |
Novel anti-CD38 antibodies for the treatment of cancer
|
PL2019104T3
(pl)
|
2007-07-19 |
2014-03-31 |
Sanofi Sa |
Środki cytotoksyczne obejmujące nowe pochodne tomaymycyny i ich zastosowanie terapeutyczne
|
AU2009243010B2
(en)
|
2008-04-30 |
2015-02-05 |
Immunogen, Inc. |
Cross-linkers and their uses
|
GB0813432D0
(en)
*
|
2008-07-22 |
2008-08-27 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
GB0819095D0
(en)
*
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
GB0819097D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
CA3014224C
(en)
*
|
2009-02-05 |
2022-05-24 |
Immunogen, Inc. |
Condensed benzodiazepine-indoline derivatives and processes to prepare said derivatives
|
AU2015224492B2
(en)
*
|
2009-02-05 |
2017-04-20 |
Immunogen, Inc. |
Novel benzodiazepine derivatives
|
HUE043645T2
(hu)
|
2009-06-03 |
2019-08-28 |
Immunogen Inc |
Konjugációs módszerek
|
FR2949469A1
(fr)
|
2009-08-25 |
2011-03-04 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application en therapeutique
|
AR078470A1
(es)
|
2009-10-02 |
2011-11-09 |
Sanofi Aventis |
Anticuerpos que se unen especificamente al receptor epha2
|
PE20130342A1
(es)
|
2010-04-15 |
2013-04-20 |
Spirogen Sarl |
Pirrolobenzodiacepinas y conjugados de las mismas
|
JP5875083B2
(ja)
*
|
2010-04-15 |
2016-03-02 |
メディミューン リミテッド |
増殖性疾患治療用ピロロベンゾジアゼピン
|
MX2012011900A
(es)
|
2010-04-15 |
2013-03-21 |
Seattle Genetics Inc |
Conjugados de pirrolobenzodiazepina diana.
|
GB201006340D0
(en)
|
2010-04-15 |
2010-06-02 |
Spirogen Ltd |
Synthesis method and intermediates
|
FR2963007B1
(fr)
|
2010-07-26 |
2013-04-05 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application therapeutique
|
KR20190089048A
(ko)
|
2011-02-15 |
2019-07-29 |
이뮤노젠 아이엔씨 |
컨쥬게이트의 제조방법
|
FR2972006B1
(fr)
|
2011-02-24 |
2016-03-25 |
Centre Nat Rech Scient |
Nouveaux fragments d'il-33 superactifs et leurs utilisations
|
US20130058947A1
(en)
|
2011-09-02 |
2013-03-07 |
Stem Centrx, Inc |
Novel Modulators and Methods of Use
|
MX341524B
(es)
|
2011-09-20 |
2016-08-24 |
Medimmune Ltd |
Pirrolobenzodiazepinas como compuestos pbd dimericos asimetricos para inclusion en conjugados dirigidos.
|
BR112014008888A2
(pt)
|
2011-10-14 |
2017-04-18 |
Seattle Genetics Inc |
pirrolobenzodiazepinas
|
ES2687246T3
(es)
|
2011-10-14 |
2018-10-24 |
Seattle Genetics, Inc. |
Pirrolobenzodiazepinas y conjugados dirigidos
|
CN104011018B
(zh)
|
2011-10-14 |
2016-12-14 |
麦迪穆有限责任公司 |
可用于制备吡咯并苯并二氮杂卓的合成方法和中间体
|
KR101877598B1
(ko)
|
2011-10-14 |
2018-07-11 |
메디뮨 리미티드 |
피롤로벤조디아제핀 및 그의 컨주게이트
|
EP3309162A1
(en)
|
2011-10-14 |
2018-04-18 |
Seattle Genetics, Inc. |
Targeted conjugates of pyrrolobenzodiazepines
|
BR112014008981A2
(pt)
|
2011-10-14 |
2017-05-02 |
Spirogen Sàrl |
pirrolobenzodiazepinas
|
ES2741936T3
(es)
|
2012-02-24 |
2020-02-12 |
Abbvie Stemcentrx Llc |
Anticuerpos anti-SEZ6 y procedimientos de uso
|
PL2817338T3
(pl)
|
2012-02-24 |
2017-12-29 |
Abbvie Stemcentrx Llc |
Modulatory DLL3 i sposoby zastosowania
|
AR090549A1
(es)
|
2012-03-30 |
2014-11-19 |
Genentech Inc |
Anticuerpos anti-lgr5 e inmunoconjugados
|
MX369715B
(es)
|
2012-04-30 |
2019-11-20 |
Ucl Business Plc |
Pirrolobenzodiacepinas.
|
AU2013255612B2
(en)
|
2012-04-30 |
2017-06-22 |
Medimmune Limited |
Pyrrolobenzodiazepines
|
EP2844300B1
(en)
|
2012-05-01 |
2018-10-17 |
Genentech, Inc. |
Anti-pmel17 antibodies and immunoconjugates
|
TW201406785A
(zh)
|
2012-07-09 |
2014-02-16 |
Genentech Inc |
抗cd22抗體及免疫結合物
|
KR20150030753A
(ko)
|
2012-07-09 |
2015-03-20 |
제넨테크, 인크. |
항-cd79b 항체를 포함하는 면역접합체
|
AR091961A1
(es)
|
2012-08-02 |
2015-03-11 |
Genentech Inc |
Inmunoconjugados y anticuerpos anti-etbr (receptor de endotelina b)
|
EP2887965A1
(en)
|
2012-08-22 |
2015-07-01 |
ImmunoGen, Inc. |
Cytotoxic benzodiazepine derivatives
|
WO2014057072A1
(en)
|
2012-10-12 |
2014-04-17 |
Spirogen Sàrl |
Synthesis and intermediates of pyrrolobenzodiazepine derivatives for conjugation
|
JP6392763B2
(ja)
|
2012-10-12 |
2018-09-19 |
エイディーシー・セラピューティクス・エス・アーAdc Therapeutics Sa |
ピロロベンゾジアゼピン−抗体結合体
|
ES2680153T3
(es)
|
2012-10-12 |
2018-09-04 |
Adc Therapeutics Sa |
Conjugados de anticuerpos anti-PSMA-pirrolobenzodiazepinas
|
EP2906297B1
(en)
|
2012-10-12 |
2017-12-06 |
ADC Therapeutics SA |
Pyrrolobenzodiazepine-antibody conjugates
|
US10751346B2
(en)
|
2012-10-12 |
2020-08-25 |
Medimmune Limited |
Pyrrolobenzodiazepine—anti-PSMA antibody conjugates
|
CA2941485C
(en)
|
2012-10-12 |
2018-06-12 |
Philip Wilson Howard |
Pyrrolobenzodiazepines and conjugates thereof
|
PT3470086T
(pt)
|
2012-10-12 |
2021-02-01 |
Medimmune Ltd |
Pirrolobenzodiazepinas e conjugados das mesmas
|
RS56520B1
(sr)
|
2012-10-12 |
2018-02-28 |
Adc Therapeutics Sa |
Pirolobenzodiazepin-anti-cd22 konjugati antitela
|
ES2670937T3
(es)
|
2012-10-12 |
2018-06-04 |
Medimmune Limited |
Conjugados de anticuerpo-pirrolobenzodiazepina
|
US10131682B2
(en)
|
2012-11-24 |
2018-11-20 |
Hangzhou Dac Biotech Co., Ltd. |
Hydrophilic linkers and their uses for conjugation of drugs to a cell binding molecules
|
EP2935268B2
(en)
|
2012-12-21 |
2021-02-17 |
MedImmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
AU2013366490B9
(en)
|
2012-12-21 |
2018-02-01 |
Medimmune Limited |
Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases
|
EP3556400A1
(en)
|
2013-02-22 |
2019-10-23 |
AbbVie Stemcentrx LLC |
Method of making antidll3-antibody pbd conjugates
|
BR112015023070B1
(pt)
|
2013-03-13 |
2022-06-07 |
Genentech, Inc. |
Conjugados e compostos de pirrolobenzodiazepinas, composição farmacêutica que compreende os mesmo, bem como seus usos para o tratamento de uma doença proliferativa
|
JP6340019B2
(ja)
|
2013-03-13 |
2018-06-06 |
メドイミューン・リミテッドMedImmune Limited |
ピロロベンゾジアゼピン及びそのコンジュゲート
|
BR112015023333A8
(pt)
|
2013-03-13 |
2018-04-17 |
Medimmune Ltd |
pirrolbenzodiazepinas e conjugados dos mesmos
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
KR20150127199A
(ko)
|
2013-03-14 |
2015-11-16 |
제넨테크, 인크. |
항-b7-h4 항체 및 면역접합체
|
WO2015023355A1
(en)
|
2013-08-12 |
2015-02-19 |
Genentech, Inc. |
1-(chloromethyl)-2,3-dihydro-1h-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment
|
CN105792836A
(zh)
|
2013-08-28 |
2016-07-20 |
施特姆森特克斯股份有限公司 |
新型sez6调节剂以及应用方法
|
EP3892294A1
(en)
|
2013-08-28 |
2021-10-13 |
AbbVie Stemcentrx LLC |
Site-specific antibody conjugation methods and compositions
|
SG11201601770YA
(en)
|
2013-09-12 |
2016-04-28 |
Halozyme Inc |
Modified anti-epidermal growth factor receptor antibodies and methods of use thereof
|
WO2015042108A1
(en)
|
2013-09-17 |
2015-03-26 |
Genentech, Inc. |
Methods of using anti-lgr5 antibodies
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
EP3054986B1
(en)
|
2013-10-11 |
2019-03-20 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
GB201317981D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
EP3054983B1
(en)
|
2013-10-11 |
2019-03-20 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
EP3054985B1
(en)
|
2013-10-11 |
2018-12-26 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
CN105813650A
(zh)
|
2013-11-06 |
2016-07-27 |
施特姆森特克斯股份有限公司 |
新型抗-密蛋白抗体和使用方法
|
CA2927806C
(en)
|
2013-11-27 |
2023-01-10 |
Redwood Bioscience, Inc. |
Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
|
WO2015089449A2
(en)
|
2013-12-12 |
2015-06-18 |
Stem Centrx, Inc. |
Novel anti-dpep3 antibodies and methods of use
|
AR098743A1
(es)
|
2013-12-13 |
2016-06-08 |
Genentech Inc |
Anticuerpos e inmunoconjugados anti-cd33
|
JP6980384B2
(ja)
|
2013-12-16 |
2021-12-15 |
ジェネンテック, インコーポレイテッド |
1−(クロロメチル)−2,3−ジヒドロ−1h−ベンゾ[e]インドール二量体抗体−薬物コンジュゲート化合物、並びに使用及び処置の方法
|
MX2016010677A
(es)
|
2014-02-21 |
2017-04-10 |
Abbvie Stemcentrx Llc |
Conjugados de anticuerpos anti-drosophila similar a delta 3 (anti-dll3) y medicamentos para usarse en el tratamiento contra melanoma.
|
CN106414465B
(zh)
|
2014-02-28 |
2021-11-16 |
杭州多禧生物科技有限公司 |
带电荷链接体及其在共轭反应上的应用
|
GB201407816D0
(en)
|
2014-05-02 |
2014-06-18 |
King S College London |
Pyrrolobenzodiazepine Compounds
|
CN106414499A
(zh)
|
2014-05-22 |
2017-02-15 |
基因泰克公司 |
抗gpc3抗体和免疫偶联物
|
MX2017002605A
(es)
|
2014-08-28 |
2017-05-19 |
Bioatla Llc |
Receptores de antigeno quimerico condicionalmente activos para celulas t modificadas.
|
EP3189057A1
(en)
|
2014-09-03 |
2017-07-12 |
ImmunoGen, Inc. |
Cytotoxic benzodiazepine derivatives
|
US9669102B2
(en)
|
2014-09-03 |
2017-06-06 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives
|
TW201617368A
(zh)
|
2014-09-05 |
2016-05-16 |
史坦森特瑞斯公司 |
新穎抗mfi2抗體及使用方法
|
US10188746B2
(en)
|
2014-09-10 |
2019-01-29 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
US9518118B2
(en)
|
2014-09-12 |
2016-12-13 |
Genentech, Inc. |
Anti-HER2 antibodies and immunoconjugates
|
RU2017107502A
(ru)
|
2014-09-12 |
2018-10-12 |
Дженентек, Инк. |
Антитела и конъюгаты, сконструированные введением цистеина
|
JP6943760B2
(ja)
|
2014-09-12 |
2021-10-06 |
ジェネンテック, インコーポレイテッド |
抗b7−h4抗体及び免疫複合体
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
WO2016040868A1
(en)
|
2014-09-12 |
2016-03-17 |
Genentech, Inc. |
Anti-cll-1 antibodies and immunoconjugates
|
CA2957148A1
(en)
|
2014-09-17 |
2016-03-24 |
Genentech, Inc. |
Immunoconjugates comprising anti-her2 antibodies and pyrrolobenzodiazepines
|
EP3223854A1
(en)
|
2014-11-25 |
2017-10-04 |
ADC Therapeutics SA |
Pyrrolobenzodiazepine-antibody conjugates
|
DK3229838T3
(da)
|
2014-12-11 |
2020-10-19 |
Pf Medicament |
Anti-C10orf54-antistoffer og anvendelser deraf
|
CA2973355A1
(en)
|
2015-01-14 |
2016-07-21 |
Bristol-Myers Squibb Company |
Heteroarylene-bridged benzodiazepine dimers, conjugates thereof, and methods of making and using
|
KR20170102980A
(ko)
|
2015-01-14 |
2017-09-12 |
브리스톨-마이어스 스큅 컴퍼니 |
벤조디아제핀 이량체, 그의 접합체, 및 제조 및 사용 방법
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
GB201510010D0
(en)
|
2015-06-09 |
2015-07-22 |
King S College London |
PDD and BPD compounds
|
JP2018518506A
(ja)
|
2015-06-23 |
2018-07-12 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
大環状ベンゾジアゼピン二量体、その結合体の製造および使用
|
CN113350518A
(zh)
|
2015-07-12 |
2021-09-07 |
杭州多禧生物科技有限公司 |
与细胞结合分子的共轭偶联的桥连接体
|
US9839687B2
(en)
|
2015-07-15 |
2017-12-12 |
Suzhou M-Conj Biotech Co., Ltd. |
Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
|
WO2017015495A1
(en)
|
2015-07-21 |
2017-01-26 |
Immunogen, Inc. |
Methods of preparing cytotoxic benzodiazepine derivatives
|
GB201514928D0
(en)
|
2015-08-21 |
2015-10-07 |
King S College London |
PDD compounds
|
US20180339985A1
(en)
|
2015-08-21 |
2018-11-29 |
Femtogenix Limited |
Pdd compounds
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
WO2017161206A1
(en)
|
2016-03-16 |
2017-09-21 |
Halozyme, Inc. |
Conjugates containing conditionally active antibodies or antigen-binding fragments thereof, and methods of use
|
KR102459684B1
(ko)
|
2016-04-15 |
2022-10-26 |
바이오아트라, 인코퍼레이티드 |
항 Axl항체 및 이의 면역접합체와 이것들의 용도
|
WO2017184942A1
(en)
|
2016-04-21 |
2017-10-26 |
Abbvie Stemcentrx Llc |
Novel anti-bmpr1b antibodies and methods of use
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
WO2017196847A1
(en)
|
2016-05-10 |
2017-11-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Variable new antigen receptor (vnar) antibodies and antibody conjugates targeting tumor and viral antigens
|
TW201808336A
(zh)
|
2016-05-11 |
2018-03-16 |
賽諾菲公司 |
用抗muc1類美登素免疫綴合物抗體治療腫瘤的治療方案
|
IL262404B2
(en)
|
2016-05-13 |
2024-04-01 |
Bioatla Llc |
Antibodies, Antibody Fragments and Their Immunomodules Against ROR2 and Their Uses
|
WO2017205741A1
(en)
|
2016-05-27 |
2017-11-30 |
Genentech, Inc. |
Bioanalytical method for the characterization of site-specific antibody-drug conjugates
|
WO2017214182A1
(en)
|
2016-06-07 |
2017-12-14 |
The United States Of America. As Represented By The Secretary, Department Of Health & Human Services |
Fully human antibody targeting pdi for cancer immunotherapy
|
WO2018026533A1
(en)
|
2016-08-02 |
2018-02-08 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monoclonal antibodies targeting glypican-2 (gpc2) and use thereof
|
WO2018027204A1
(en)
|
2016-08-05 |
2018-02-08 |
Genentech, Inc. |
Multivalent and multiepitopic anitibodies having agonistic activity and methods of use
|
EP3496763A1
(en)
|
2016-08-11 |
2019-06-19 |
Genentech, Inc. |
Pyrrolobenzodiazepine prodrugs and antibody conjugates thereof
|
EP3525829A1
(en)
|
2016-10-11 |
2019-08-21 |
Medimmune Limited |
Antibody-drug conjugates with immune-mediated therapy agents
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
NZ752394A
(en)
|
2016-11-14 |
2021-07-30 |
Hangzhou Dac Biotech Co Ltd |
Conjugation linkers, cell binding molecule-drug conjugates containing the likers, methods of making and uses such conjugates with the linkers
|
KR102532256B1
(ko)
|
2016-11-21 |
2023-05-12 |
쿠레아브 게엠베하 |
항-gp73 항체 및 면역접합체
|
FR3059550B1
(fr)
|
2016-12-01 |
2020-01-03 |
Universite De Rouen Normandie |
Traitement des troubles causes par l'alcoolisation foetale (tcaf)
|
WO2018119279A1
(en)
|
2016-12-21 |
2018-06-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies specific for flt3 and uses thereof
|
MX2019009428A
(es)
|
2017-02-08 |
2019-10-07 |
Adc Therapeutics Sa |
Conjugados de pirrolobenzodiazepinas y anticuerpos.
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
HUE059828T2
(hu)
|
2017-04-18 |
2023-01-28 |
Medimmune Ltd |
Pirrolobenzodiazepin konjugátumok
|
US20180346488A1
(en)
|
2017-04-20 |
2018-12-06 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives and conjugates thereof
|
JP7408396B2
(ja)
|
2017-04-20 |
2024-01-05 |
アーデーセー セラピューティクス ソシエテ アノニム |
併用療法
|
AU2018268970A1
(en)
|
2017-05-19 |
2019-10-24 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibody targeting tnfr2 for cancer immunotherapy
|
BR112019026564A2
(pt)
|
2017-06-14 |
2020-06-30 |
Adc Therapeutics Sa |
regimes de dosagem para a administração de um adc anti-cd19
|
WO2019005208A1
(en)
|
2017-06-30 |
2019-01-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
ANTIBODIES TO HUMAN MESOTHELIN AND USES IN ANTICANCER THERAPY
|
WO2019006280A1
(en)
|
2017-06-30 |
2019-01-03 |
Lentigen Technology, Inc. |
HUMAN MONOCLONAL ANTIBODIES SPECIFIC TO CD33 AND METHODS OF USE
|
LT3668874T
(lt)
|
2017-08-18 |
2022-03-25 |
Medimmune Limited |
Pirolobenzodiazepino konjugatai
|
CN111164208B
(zh)
|
2017-09-29 |
2023-08-04 |
第一三共株式会社 |
抗体-吡咯并苯并二氮杂卓衍生物偶联物
|
CN111417409B
(zh)
|
2017-11-14 |
2022-07-08 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂䓬缀合物
|
MA51184A
(fr)
|
2017-12-15 |
2020-10-21 |
Juno Therapeutics Inc |
Molécules de liaison à l'anti-cct5 et procédés d'utilisation associés
|
EP3732178A1
(en)
|
2017-12-28 |
2020-11-04 |
ImmunoGen, Inc. |
Benzodiazepine derivatives
|
GB201803342D0
(en)
*
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
WO2019224340A1
(en)
|
2018-05-25 |
2019-11-28 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
FR3081707A1
(fr)
|
2018-05-30 |
2019-12-06 |
Universite De Rouen Normandie |
Traitement des troubles neurologiques causes par l'alcoolisation foetale
|
EP3820903A1
(en)
|
2018-07-12 |
2021-05-19 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Affinity matured cd22-specific monoclonal antibody and uses thereof
|
EP3833684A1
(en)
|
2018-08-08 |
2021-06-16 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
High affinity monoclonal antibodies targeting glypican-2 and uses thereof
|
CN113286617A
(zh)
|
2018-10-19 |
2021-08-20 |
免疫医疗有限公司 |
吡咯并苯并二氮杂䓬缀合物
|
US20210316006A1
(en)
|
2018-10-19 |
2021-10-14 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
TW202039573A
(zh)
|
2018-12-21 |
2020-11-01 |
美商亞維代堤生物科學公司 |
抗轉鐵蛋白受體抗體及其用途
|
CN113490510A
(zh)
|
2019-01-08 |
2021-10-08 |
美国政府(由卫生和人类服务部的部长所代表) |
用于治疗实体瘤的靶向间皮素的跨物种单结构域抗体
|
EP3883971A1
(en)
|
2019-01-22 |
2021-09-29 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
High affinity monoclonal antibodies targeting glypican-1 and methods of use
|
AU2020214796A1
(en)
|
2019-01-30 |
2021-07-29 |
Truebinding, Inc. |
Anti-Gal3 antibodies and uses thereof
|
EP3938372B1
(en)
|
2019-03-15 |
2023-10-25 |
MedImmune Limited |
Azetidobenzodiazepine dimers and conjugates comprising them for use in the treatment of cancer
|
CN113661172A
(zh)
|
2019-03-29 |
2021-11-16 |
伊缪诺金公司 |
用于抑制异常细胞生长或治疗增生性疾病的细胞毒性双苯并二氮杂䓬衍生物及其与细胞结合剂的缀合物
|
US20220380471A1
(en)
|
2019-10-22 |
2022-12-01 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
High affinity nanobodies targeting b7-h3 (cd276) for treating multiple solid tumors
|
WO2021118968A1
(en)
|
2019-12-12 |
2021-06-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Antibody-drug conjugates specific for cd276 and uses thereof
|
EP4121063A1
(en)
|
2020-03-19 |
2023-01-25 |
Avidity Biosciences, Inc. |
Compositions and methods of treating facioscapulohumeral muscular dystrophy
|
IL296393A
(en)
|
2020-03-27 |
2022-11-01 |
Avidity Biosciences Inc |
Preparations and methods for the treatment of muscle atrophy
|
US20230391852A1
(en)
|
2020-10-26 |
2023-12-07 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Single domain antibodies targeting sars coronavirus spike protein and uses thereof
|
WO2022232612A1
(en)
|
2021-04-29 |
2022-11-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Lassa virus-specific nanobodies and methods of their use
|
AU2022291120A1
(en)
|
2021-06-09 |
2023-11-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Cross species single domain antibodies targeting pd-l1 for treating solid tumors
|
WO2023043953A1
(en)
|
2021-09-16 |
2023-03-23 |
Avidity Biosciences, Inc. |
Compositions and methods of treating facioscapulohumeral muscular dystrophy
|
WO2023215737A1
(en)
|
2022-05-03 |
2023-11-09 |
Genentech, Inc. |
Anti-ly6e antibodies, immunoconjugates, and uses thereof
|