|
GB9818730D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collections of compounds
|
|
GB9818732D0
(en)
*
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collection of compounds
|
|
GB9818731D0
(en)
*
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Compounds
|
|
ATE240334T1
(de)
|
1998-08-27 |
2003-05-15 |
Spirogen Ltd |
Pyrrolobenzodiazepine
|
|
GB0226593D0
(en)
|
2002-11-14 |
2002-12-24 |
Consultants Ltd |
Compounds
|
|
DE60326060D1
(de)
*
|
2003-03-31 |
2009-03-19 |
Council Scient Ind Res |
Nichtvernetzende pyrroloä2,1-cüä1,4übenzodiazepine als potentielle antitumor-agentien und ihre herstellung
|
|
GB0321295D0
(en)
|
2003-09-11 |
2003-10-15 |
Spirogen Ltd |
Synthesis of protected pyrrolobenzodiazepines
|
|
EP1675857B1
(de)
|
2003-10-22 |
2011-07-13 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
Pyrrolobenzodiazepinderivate, zusammensetzungen, die diese enthalten, und damit in zusammenhang stehende verfahren
|
|
GB0416511D0
(en)
*
|
2003-10-22 |
2004-08-25 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
WO2005040172A1
(ja)
*
|
2003-10-29 |
2005-05-06 |
Kyowa Hakko Kogyo Co., Ltd. |
三環性プロリン誘導体
|
|
JP4520411B2
(ja)
*
|
2003-12-31 |
2010-08-04 |
カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ |
ピロロ［２，１−ｃ］［１，４］ベンゾジアゼピン・ハイブリッドの調製方法
|
|
JP4718328B2
(ja)
*
|
2003-12-31 |
2011-07-06 |
カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ |
Ｃ８連結したピロロ［２，１−ｃ］［１，４］ベンゾジアゼピン−アクリドン／アクリジン・ハイブリッド
|
|
GB0404574D0
(en)
*
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Amino acids
|
|
GB0404577D0
(en)
*
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
PL1720881T3
(pl)
*
|
2004-03-01 |
2013-05-31 |
Medimmune Ltd |
Pochodne 11-hydroksy-5h-pirolo[2,1-c][1,4]benzodiazepin-5-onu jako kluczowe związki pośrednie do otrzymywania C2 podstawionych pirolobenzodiazepin
|
|
GB0404578D0
(en)
*
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
US7528126B2
(en)
|
2004-03-09 |
2009-05-05 |
Spirogen Limited |
Pyrrolobenzodiazepines
|
|
US6951853B1
(en)
|
2004-03-30 |
2005-10-04 |
Council Of Scientific And Industrial Research |
Process for preparing pyrrolo[2, 1-c] [1,4] benzodiazepine hybrids
|
|
US7056913B2
(en)
|
2004-03-30 |
2006-06-06 |
Council Of Scientific And Industrial Research |
C8—linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids
|
|
FR2869231B1
(fr)
*
|
2004-04-27 |
2008-03-14 |
Sod Conseils Rech Applic |
Composition therapeutique contenant au moins un derive de la pyrrolobenzodiazepine et la fludarabine
|
|
GB0410725D0
(en)
*
|
2004-05-13 |
2004-06-16 |
Spirogen Ltd |
Pyrrolobenzodiazepine therapeutic agents
|
|
GB2439881C
(en)
|
2005-04-21 |
2011-08-10 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0508084D0
(en)
*
|
2005-04-21 |
2005-06-01 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
WO2007039752A1
(en)
*
|
2005-10-05 |
2007-04-12 |
Spirogen Limited |
Alkyl 4- [4- (5-oxo-2, 3, 5, 11a-tetrahyd0-5h-pyrr0l0 [2, 1-c] [1, 4] benzodiazepine-8-yloxy) -butyrylamino]-1h-pyrrole-2-carboxylate derivatives and related compounds for the treatment of a proliferative disease
|
|
SI1813614T1
(sl)
|
2006-01-25 |
2012-01-31 |
Sanofi 174 |
Citotoksična sredstva, ki obsegajo nove tomajmicinske derivate
|
|
DE102006013678A1
(de)
*
|
2006-03-24 |
2007-09-27 |
Bayerische Motoren Werke Ag |
Gleit- oder Schmiermittel und Verfahren zum Aufziehen eines Fahrzeugreifens auf eine Felge
|
|
USRE47123E1
(en)
|
2006-07-18 |
2018-11-13 |
Sanofi |
EPHA2 receptor antagonist antibodies
|
|
GB0619325D0
(en)
|
2006-09-30 |
2006-11-08 |
Univ Strathclyde |
New compounds
|
|
EP1914242A1
(de)
|
2006-10-19 |
2008-04-23 |
Sanofi-Aventis |
Neue Antikörper gegen CD38 zur Behandlung von Krebs
|
|
ES2435779T3
(es)
|
2007-07-19 |
2013-12-23 |
Sanofi |
Agentes citotóxicos que comprenden nuevos derivados de tomaimicina y su uso terapéutico
|
|
DK2281006T3
(da)
|
2008-04-30 |
2017-11-06 |
Immunogen Inc |
Tværbindingsmidler og anvendelser deraf
|
|
GB0813432D0
(en)
|
2008-07-22 |
2008-08-27 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0819095D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0819097D0
(en)
*
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
BRPI1008749B8
(pt)
*
|
2009-02-05 |
2021-05-25 |
Immunogen Inc |
compostos derivados de benzodiazepina, seus conjugados, composição farmacêutica, seu uso e seus processos de preparação
|
|
AU2015224492B2
(en)
*
|
2009-02-05 |
2017-04-20 |
Immunogen, Inc. |
Novel benzodiazepine derivatives
|
|
HUE043645T2
(hu)
|
2009-06-03 |
2019-08-28 |
Immunogen Inc |
Konjugációs módszerek
|
|
FR2949469A1
(fr)
|
2009-08-25 |
2011-03-04 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application en therapeutique
|
|
TW201116297A
(en)
|
2009-10-02 |
2011-05-16 |
Sanofi Aventis |
Antibodies that specifically bind to the EphA2 receptor
|
|
GB201006340D0
(en)
*
|
2010-04-15 |
2010-06-02 |
Spirogen Ltd |
Synthesis method and intermediates
|
|
KR101687054B1
(ko)
|
2010-04-15 |
2016-12-15 |
메디뮨 리미티드 |
증식성 질환 치료용 피롤로벤조디아제핀
|
|
PH12012501836A1
(en)
|
2010-04-15 |
2013-02-04 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
WO2011130613A1
(en)
|
2010-04-15 |
2011-10-20 |
Seattle Genetics, Inc. |
Targeted pyrrolobenzodiazapine conjugates
|
|
FR2963007B1
(fr)
|
2010-07-26 |
2013-04-05 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application therapeutique
|
|
UA120696C2
(uk)
|
2011-02-15 |
2020-01-27 |
Імуноген, Інк. |
Спосіб одержання кон'югатів
|
|
FR2972006B1
(fr)
|
2011-02-24 |
2016-03-25 |
Centre Nat Rech Scient |
Nouveaux fragments d'il-33 superactifs et leurs utilisations
|
|
US20130058947A1
(en)
|
2011-09-02 |
2013-03-07 |
Stem Centrx, Inc |
Novel Modulators and Methods of Use
|
|
BR112014006703A8
(pt)
|
2011-09-20 |
2018-01-09 |
Spirogen Sarl |
"pirrolobenzodiazepinas
|
|
CN103998449A
(zh)
|
2011-10-14 |
2014-08-20 |
斯皮罗根有限公司 |
吡咯并苯并二氮杂卓
|
|
BR112014008888A2
(pt)
|
2011-10-14 |
2017-04-18 |
Seattle Genetics Inc |
pirrolobenzodiazepinas
|
|
BR122021017842B1
(pt)
|
2011-10-14 |
2021-12-14 |
Medimmune Limited |
Compostos pirrolobenzodiazepinas e conjugados alvos
|
|
CN108164551A
(zh)
|
2011-10-14 |
2018-06-15 |
西雅图基因公司 |
吡咯并苯并二氮杂卓和靶向结合物
|
|
EA026827B1
(ru)
|
2011-10-14 |
2017-05-31 |
Медимьюн Лимитед |
Пирролбензодиазепины и их конъюгаты
|
|
WO2013053872A1
(en)
|
2011-10-14 |
2013-04-18 |
Spirogen Sàrl |
Synthesis method and intermediates useful in the preparation of pyrrolobenzodiazepines
|
|
CA2865404C
(en)
|
2012-02-24 |
2019-08-27 |
Stem Centrx, Inc. |
Dll3-binding antibodies and drug conjugates thereof to treat cancer
|
|
US9676850B2
(en)
|
2012-02-24 |
2017-06-13 |
Abbvie Stemcentrx Llc |
Anti SEZ6 antibodies and methods of use
|
|
AR090549A1
(es)
|
2012-03-30 |
2014-11-19 |
Genentech Inc |
Anticuerpos anti-lgr5 e inmunoconjugados
|
|
WO2013164592A1
(en)
|
2012-04-30 |
2013-11-07 |
Ucl Business Plc |
Pyrrolobenzodiazepines
|
|
ES2623042T3
(es)
|
2012-04-30 |
2017-07-10 |
Medimmune Limited |
Pirrolobenzodiacepinas
|
|
AR090903A1
(es)
|
2012-05-01 |
2014-12-17 |
Genentech Inc |
Anticuerpos e inmunoconjugados anti-pmel17
|
|
MX2015000357A
(es)
|
2012-07-09 |
2015-05-12 |
Genentech Inc |
Anticuerpos e inmunoconjugados anti-cd22.
|
|
BR112015000437A2
(pt)
|
2012-07-09 |
2017-06-27 |
Genentech Inc |
imunoconjugados, formulação farmacêutica, métodos de tratamento e de inbir a proliferação de uma célula
|
|
KR20150039818A
(ko)
|
2012-08-02 |
2015-04-13 |
제넨테크, 인크. |
항-etbr 항체 및 면역접합체
|
|
HK1211208A1
(zh)
|
2012-08-22 |
2016-05-20 |
Immunogen, Inc. |
細胞毒性苯並二氮呯衍生物
|
|
ES2660029T3
(es)
|
2012-10-12 |
2018-03-20 |
Medimmune Limited |
Conjugados de anticuerpo-pirrolobenzodiazepinas
|
|
RS56520B1
(sr)
|
2012-10-12 |
2018-02-28 |
Adc Therapeutics Sa |
Pirolobenzodiazepin-anti-cd22 konjugati antitela
|
|
HUE042731T2
(hu)
|
2012-10-12 |
2019-07-29 |
Adc Therapeutics Sa |
Pirrolobenzodiazepin-antitest konjugátumok
|
|
LT2906296T
(lt)
|
2012-10-12 |
2018-06-11 |
Adc Therapeutics Sa |
Pirolobenzodiazepino-antikūno konjugatai
|
|
JP6367204B2
(ja)
|
2012-10-12 |
2018-08-01 |
メドイミューン・リミテッドＭｅｄＩｍｍｕｎｅ Ｌｉｍｉｔｅｄ |
結合用のピロロベンゾジアゼピン誘導体の合成および中間体
|
|
WO2014057114A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-anti-psma antibody conjugates
|
|
US10751346B2
(en)
|
2012-10-12 |
2020-08-25 |
Medimmune Limited |
Pyrrolobenzodiazepine—anti-PSMA antibody conjugates
|
|
CA2885340C
(en)
|
2012-10-12 |
2016-11-08 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
TR201902494T4
(tr)
|
2012-10-12 |
2019-03-21 |
Medimmune Ltd |
Pirrolobenzodiazepinler ve onların konjugatları.
|
|
CN105849086B
(zh)
|
2012-11-24 |
2018-07-31 |
杭州多禧生物科技有限公司 |
亲水性链接体及其在药物分子和细胞结合分子共轭反应上的应用
|
|
EP2935273A1
(de)
|
2012-12-21 |
2015-10-28 |
MedImmune Limited |
Asymmetrische pyrrolobenzodiazepin-dimere zur verwendung bei der behandlung von proliferativen und autoimmunerkrankungen
|
|
US9562049B2
(en)
|
2012-12-21 |
2017-02-07 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
MX2015010682A
(es)
|
2013-02-22 |
2016-05-31 |
Stemcentrx Inc |
Nuevos conjugados de anticuerpos y usos de los mismos.
|
|
KR102066318B1
(ko)
|
2013-03-13 |
2020-01-14 |
메디뮨 리미티드 |
피롤로벤조디아제핀 및 그의 컨쥬게이트
|
|
TWI680766B
(zh)
|
2013-03-13 |
2020-01-01 |
英商梅迪繆思有限公司 |
吡咯并苯并二氮呯及其共軛物
|
|
KR102066319B1
(ko)
|
2013-03-13 |
2020-01-14 |
메디뮨 리미티드 |
피롤로벤조디아제핀 및 그의 컨쥬게이트
|
|
EA201591750A1
(ru)
|
2013-03-14 |
2016-05-31 |
Дженентек, Инк. |
Антитела против b7-h4 и иммуноконъюгаты
|
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
|
EP3033111B1
(de)
|
2013-08-12 |
2019-03-13 |
Genentech, Inc. |
1-(chlormethyl) 2,3-dihydro-1h-benzo[e]indoldimer-antikörper-wirkstoff-konjugatverbindungen und verfahren zur verwendung und behandlung
|
|
JP2016531915A
(ja)
|
2013-08-28 |
2016-10-13 |
ステムセントリックス， インコーポレイテッド |
部位特異的抗体コンジュゲーション方法および組成物
|
|
EP3038634A4
(de)
|
2013-08-28 |
2017-10-11 |
AbbVie Stemcentrx LLC |
Neuartige sez6-modulatoren und verfahren zur verwendung
|
|
US20150071923A1
(en)
|
2013-09-12 |
2015-03-12 |
Ge Wei |
Modified anti-epidermal growth factor receptor antibodies and methods of use thereof
|
|
RU2016109247A
(ru)
|
2013-09-17 |
2017-10-19 |
Дженентек, Инк. |
Способы применения антител к lgr5
|
|
GB201317981D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
US10010624B2
(en)
|
2013-10-11 |
2018-07-03 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
WO2015052534A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
EP3054986B1
(de)
|
2013-10-11 |
2019-03-20 |
Medimmune Limited |
Pyrrolobenzodiazepin-antikörper-konjugate
|
|
BR112016010169A2
(pt)
|
2013-11-06 |
2017-12-05 |
Stemcentrx Inc |
anticorpos anticlaudina e métodos de uso
|
|
WO2015081282A1
(en)
|
2013-11-27 |
2015-06-04 |
Redwood Bioscience, Inc. |
Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
|
|
JP2017500028A
(ja)
|
2013-12-12 |
2017-01-05 |
アッヴィ・ステムセントルクス・エル・エル・シー |
新規の抗ｄｐｅｐ３抗体および使用方法
|
|
AR098743A1
(es)
|
2013-12-13 |
2016-06-08 |
Genentech Inc |
Anticuerpos e inmunoconjugados anti-cd33
|
|
CN105828840B
(zh)
|
2013-12-16 |
2020-08-04 |
基因泰克公司 |
1-(氯甲基)-2,3-二氢-1H-苯并[e]吲哚二聚体抗体-药物缀合物化合物及使用和治疗方法
|
|
WO2015127407A1
(en)
|
2014-02-21 |
2015-08-27 |
Stemcentrx, Inc. |
Anti-dll3 antibodies and drug conjugates for use in melanoma
|
|
DK3122757T3
(da)
|
2014-02-28 |
2023-10-09 |
Hangzhou Dac Biotech Co Ltd |
Ladede linkere og anvendelse deraf til konjugering
|
|
GB201407816D0
(en)
|
2014-05-02 |
2014-06-18 |
King S College London |
Pyrrolobenzodiazepine Compounds
|
|
RU2016150370A
(ru)
|
2014-05-22 |
2018-06-26 |
Дженентек, Инк. |
Антитела и иммуноконъюгаты против GPC3
|
|
ES3034398T3
(en)
|
2014-08-28 |
2025-08-18 |
Bioatla Inc |
Conditionally active chimeric antigen receptors for modified t-cells
|
|
SG11201701455SA
(en)
|
2014-09-03 |
2017-03-30 |
Immunogen Inc |
Cytotoxic benzodiazepine derivatives
|
|
TW201613930A
(en)
|
2014-09-03 |
2016-04-16 |
Immunogen Inc |
Cytotoxic benzodiazepine derivatives
|
|
TW201617368A
(zh)
|
2014-09-05 |
2016-05-16 |
史坦森特瑞斯公司 |
新穎抗ｍｆｉ２抗體及使用方法
|
|
CN106687141A
(zh)
|
2014-09-10 |
2017-05-17 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂卓及其缀合物
|
|
TWI758784B
(zh)
|
2014-09-12 |
2022-03-21 |
美商建南德克公司 |
抗her2抗體及免疫結合物
|
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
CA2957354A1
(en)
|
2014-09-12 |
2016-03-17 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
|
EP3191518B1
(de)
|
2014-09-12 |
2020-01-15 |
Genentech, Inc. |
Anti-b7-h4-antikörper und immunkonjugate
|
|
SG11201701627PA
(en)
|
2014-09-12 |
2017-03-30 |
Genentech Inc |
Anti-cll-1 antibodies and immunoconjugates
|
|
HK1243629A1
(zh)
|
2014-09-17 |
2018-07-20 |
基因泰克公司 |
包含抗her2抗体和吡咯并苯并二氮杂䓬的免疫缀合物
|
|
US10780096B2
(en)
|
2014-11-25 |
2020-09-22 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates
|
|
DK3229838T3
(da)
|
2014-12-11 |
2020-10-19 |
Pf Medicament |
Anti-C10orf54-antistoffer og anvendelser deraf
|
|
EA201791550A1
(ru)
|
2015-01-14 |
2017-11-30 |
Бристол-Маерс Сквибб Компани |
Димеры бензодиазепинов, их конъюгаты и способы их получения и применения
|
|
PE20171185A1
(es)
|
2015-01-14 |
2017-08-22 |
Bristol Myers Squibb Co |
Dimeros de benzodiazepina unidos con puentes de heteroarileno, conjugados de estos, y sus metodos de preparacion y uso
|
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
|
GB201510010D0
(en)
|
2015-06-09 |
2015-07-22 |
King S College London |
PDD and BPD compounds
|
|
CN108026123B
(zh)
|
2015-06-15 |
2021-02-05 |
杭州多禧生物科技有限公司 |
用于偶联的亲水链接体
|
|
EA201792516A1
(ru)
|
2015-06-23 |
2018-05-31 |
Бристол-Маерс Сквибб Компани |
Макроциклические димеры бензодиазепина, их конъюгаты, получение и применение
|
|
FI3319936T3
(fi)
|
2015-07-12 |
2026-03-12 |
Hangzhou Dac Biotech Co Ltd |
Silloituslinkkereitä soluun sitoutuvien molekyylien konjugoimiseksi
|
|
US9839687B2
(en)
|
2015-07-15 |
2017-12-12 |
Suzhou M-Conj Biotech Co., Ltd. |
Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
|
|
JP2018522018A
(ja)
|
2015-07-21 |
2018-08-09 |
イミュノジェン・インコーポレーテッド |
細胞毒性ベンゾジアゼピン誘導体の調製方法
|
|
GB201514928D0
(en)
|
2015-08-21 |
2015-10-07 |
King S College London |
PDD compounds
|
|
US20180339985A1
(en)
|
2015-08-21 |
2018-11-29 |
Femtogenix Limited |
Pdd compounds
|
|
EP3350224B1
(de)
|
2015-09-20 |
2024-06-19 |
The United States of America, as Represented By the Secretary, Department of Health and Human Services |
Für fibroblastenwachstumsfaktor-rezeptor 4 (fgfr4) spezifische monoklonale antikörper und verfahren zu deren verwendung
|
|
AU2016331931C1
(en)
|
2015-10-02 |
2020-01-16 |
Genentech, Inc. |
Pyrrolobenzodiazepine antibody drug conjugates and methods of use
|
|
JP6621919B2
(ja)
|
2015-10-16 |
2019-12-18 |
ジェネンテック， インコーポレイテッド |
束縛ジスルフィド薬物コンジュゲート
|
|
IL259186B2
(en)
|
2015-11-09 |
2023-03-01 |
Scherer Technologies Llc R P |
Anti-cd22-maytensin antibody conjugates and methods of using them
|
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
WO2017161206A1
(en)
|
2016-03-16 |
2017-09-21 |
Halozyme, Inc. |
Conjugates containing conditionally active antibodies or antigen-binding fragments thereof, and methods of use
|
|
JP2019513371A
(ja)
|
2016-04-01 |
2019-05-30 |
アビディティー バイオサイエンシーズ エルエルシー |
核酸ポリペプチド組成物とその使用
|
|
AU2017248644B2
(en)
|
2016-04-15 |
2019-10-31 |
Bioatla, Llc |
Anti-Axl antibodies, antibody fragments and their immunoconjugates and uses thereof
|
|
EP3454864A4
(de)
|
2016-04-21 |
2021-01-13 |
Abbvie Stemcentrx LLC |
Neuartige anti-bmpr1b-antikörper und verfahren zur verwendung
|
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
WO2017196847A1
(en)
|
2016-05-10 |
2017-11-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Variable new antigen receptor (vnar) antibodies and antibody conjugates targeting tumor and viral antigens
|
|
WO2017194568A1
(en)
|
2016-05-11 |
2017-11-16 |
Sanofi |
Treatment regimen using anti-muc1 maytansinoid immunoconjugate antibody for the treatment of tumors
|
|
LT3455261T
(lt)
|
2016-05-13 |
2022-11-10 |
Bioatla, Inc. |
Antikūnai prieš ror2, antikūnų fragmentai, jų imunokonjugatai ir panaudojimas
|
|
CN109313200B
(zh)
|
2016-05-27 |
2022-10-04 |
豪夫迈·罗氏有限公司 |
用于表征位点特异性抗体-药物缀合物的生物分析性方法
|
|
WO2017214182A1
(en)
|
2016-06-07 |
2017-12-14 |
The United States Of America. As Represented By The Secretary, Department Of Health & Human Services |
Fully human antibody targeting pdi for cancer immunotherapy
|
|
CA3031559A1
(en)
|
2016-08-02 |
2018-02-08 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monoclonal antibodies targeting glypican-2 (gpc2) and use thereof
|
|
WO2018027204A1
(en)
|
2016-08-05 |
2018-02-08 |
Genentech, Inc. |
Multivalent and multiepitopic anitibodies having agonistic activity and methods of use
|
|
WO2018031662A1
(en)
|
2016-08-11 |
2018-02-15 |
Genentech, Inc. |
Pyrrolobenzodiazepine prodrugs and antibody conjugates thereof
|
|
JP2019534882A
(ja)
|
2016-10-11 |
2019-12-05 |
メドイミューン・リミテッドＭｅｄＩｍｍｕｎｅ Ｌｉｍｉｔｅｄ |
免疫介在性療法薬を有する抗体−薬物コンジュゲート
|
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
|
KR20220147721A
(ko)
|
2016-11-14 |
2022-11-03 |
항저우 디에이씨 바이오테크 씨오, 엘티디 |
결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
|
|
CA3036983A1
(en)
|
2016-11-21 |
2018-05-24 |
Cureab Gmbh |
Anti-gp73 antibodies and immunoconjugates
|
|
FR3059550B1
(fr)
|
2016-12-01 |
2020-01-03 |
Universite De Rouen Normandie |
Traitement des troubles causes par l'alcoolisation foetale (tcaf)
|
|
US11236171B2
(en)
|
2016-12-21 |
2022-02-01 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies specific for FLT3 and uses thereof
|
|
HRP20210979T1
(hr)
|
2017-02-08 |
2021-09-17 |
Adc Therapeutics Sa |
Konjugati pirolobenzodiazepin-protutijelo
|
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
|
PT3612537T
(pt)
*
|
2017-04-18 |
2022-08-29 |
Medimmune Ltd |
Conjugados de pirrolobenzodiazepina
|
|
WO2018195243A1
(en)
|
2017-04-20 |
2018-10-25 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives and conjugates thereof
|
|
MX2019012464A
(es)
|
2017-04-20 |
2019-12-11 |
Adc Therapeutics Sa |
Terapia combinada con un conjugado de anticuerpo y farmaco anti-axl.
|
|
EP3625256A1
(de)
|
2017-05-19 |
2020-03-25 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Humaner monoklonaler antikörper gegen tnfr2 zur krebsimmuntherapie
|
|
BR112019026564A2
(pt)
|
2017-06-14 |
2020-06-30 |
Adc Therapeutics Sa |
regimes de dosagem para a administração de um adc anti-cd19
|
|
CA3066953A1
(en)
|
2017-06-30 |
2019-01-03 |
Lentigen Technology, Inc. |
Human monoclonal antibodies specific for cd33 and methods of their use
|
|
WO2019005208A1
(en)
|
2017-06-30 |
2019-01-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
ANTIBODIES TO HUMAN MESOTHELIN AND USES IN ANTICANCER THERAPY
|
|
JP7368856B2
(ja)
|
2017-07-25 |
2023-10-25 |
トゥルーバインディング，インコーポレイテッド |
Ｔｉｍ－３とそのリガンドとの相互作用の遮断によるがん治療
|
|
SMT202200225T1
(it)
|
2017-08-18 |
2022-07-21 |
Medimmune Ltd |
Coniugati di pirrolobenzodiazepina
|
|
IL301636B2
(en)
|
2017-09-29 |
2025-02-01 |
Daiichi Sankyo Co Ltd |
Conjugation of an antibody with a pyrrolobenzodiazepine derivative
|
|
US20200289660A1
(en)
|
2017-11-14 |
2020-09-17 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
|
KR20200110745A
(ko)
|
2017-12-15 |
2020-09-25 |
주노 쎄러퓨티크스 인코퍼레이티드 |
항 - ｃｃｔ5 결합 분자 및 이의 사용 방법
|
|
WO2019133652A1
(en)
|
2017-12-28 |
2019-07-04 |
Immunogen, Inc. |
Benzodiazepine derivatives
|
|
GB201803342D0
(en)
*
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
EP3801630A1
(de)
|
2018-05-25 |
2021-04-14 |
Medimmune Limited |
Pyrrolobenzodiazepinkonjugate
|
|
FR3081707A1
(fr)
|
2018-05-30 |
2019-12-06 |
Universite De Rouen Normandie |
Traitement des troubles neurologiques causes par l'alcoolisation foetale
|
|
WO2020014482A1
(en)
|
2018-07-12 |
2020-01-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Affinity matured cd22-specific monoclonal antibody and uses thereof
|
|
US12012463B2
(en)
|
2018-08-08 |
2024-06-18 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
High affinity monoclonal antibodies targeting glypican-2 and uses thereof
|
|
AU2019363153A1
(en)
|
2018-10-19 |
2021-05-06 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
|
WO2020079239A1
(en)
|
2018-10-19 |
2020-04-23 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
|
EP3883967A4
(de)
|
2018-11-16 |
2023-04-19 |
Virtuoso Binco, Inc. |
Cd38- und icam1-antikörper und verwendungen davon
|
|
IL319265A
(en)
|
2018-12-21 |
2025-04-01 |
Avidity Biosciences Inc |
Anti-transferrin receptor antibodies and their uses
|
|
EP3883608A1
(de)
|
2019-01-08 |
2021-09-29 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Speziesübergreifende einzeldomänenantikörper gegen mesothelin zur behandlung von soliden tumoren
|
|
US12122843B2
(en)
|
2019-01-22 |
2024-10-22 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
High affinity monoclonal antibodies targeting glypican-1 and methods of use
|
|
CN120058944A
(zh)
|
2019-01-30 |
2025-05-30 |
真和制药有限公司 |
抗gal3抗体及其用途
|
|
EP3938372B1
(de)
|
2019-03-15 |
2023-10-25 |
MedImmune Limited |
Azetidobenzodiazepindimere und konjugate damit zur verwendung in der behandlung von krebs
|
|
KR20220010481A
(ko)
|
2019-03-29 |
2022-01-25 |
이뮤노젠 아이엔씨 |
비정상 세포 성장의 억제 또는 증식성 질환의 치료를 위한 세포독성 비스-벤조디아제핀 유도체 및 세포결합제와 이의 접합체
|
|
EP4031250A1
(de)
|
2019-10-22 |
2022-07-27 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Gegen b7h3 (cd276) gerichtete hochaffine nanokörper zur behandlung von multiplen soliden tumoren
|
|
EP4069749A4
(de)
|
2019-12-06 |
2023-12-20 |
TrueBinding, Inc. |
Antikörper, die die wechselwirkung von gal3 und insulinrezeptor oder integrinen unterbrechen, und verfahren zur verwendung davon
|
|
AU2020402752A1
(en)
|
2019-12-12 |
2022-06-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Antibody-drug conjugates specific for CD276 and uses thereof
|
|
EP4121063A4
(de)
|
2020-03-19 |
2024-07-03 |
Avidity Biosciences, Inc. |
Zusammensetzungen und verfahren zur behandlung von fazioskapulohumeraler muskeldystrophie
|
|
CN115697418B
(zh)
|
2020-03-27 |
2025-12-30 |
艾维迪提生物科学公司 |
治疗肌营养不良的组合物和方法
|
|
CA3185040A1
(en)
|
2020-05-26 |
2021-12-02 |
Truebinding, Inc. |
Methods of treating inflammatory diseases by blocking galectin-3
|
|
US20230391852A1
(en)
|
2020-10-26 |
2023-12-07 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Single domain antibodies targeting sars coronavirus spike protein and uses thereof
|
|
WO2022232612A1
(en)
|
2021-04-29 |
2022-11-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Lassa virus-specific nanobodies and methods of their use
|
|
US20240270851A1
(en)
|
2021-06-09 |
2024-08-15 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Cross species single domain antibodies targeting pd-l1 for treating solid tumors
|
|
WO2023288252A1
(en)
|
2021-07-13 |
2023-01-19 |
Truebinding, Inc. |
Methods of preventing protein aggregation
|
|
JP7742485B2
(ja)
|
2021-09-16 |
2025-09-19 |
アビディティー バイオサイエンシーズ，インク． |
顔面肩甲上腕型筋ジストロフィーを処置する組成物および方法
|
|
JP2024541058A
(ja)
|
2021-11-03 |
2024-11-06 |
ハンジョウ ディーエーシー バイオテック シーオー．，エルティディ． |
抗体の特異的共役
|
|
WO2023086768A1
(en)
|
2021-11-09 |
2023-05-19 |
Truebinding, Inc. |
Methods of treating or inhibiting cardiovascular diseases
|
|
TW202406934A
(zh)
|
2022-05-03 |
2024-02-16 |
美商建南德克公司 |
抗Ｌｙ６Ｅ抗體、免疫結合物及其用途
|
|
AU2024295016A1
(en)
|
2023-07-20 |
2026-02-05 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Fully human monoclonal antibodies and chimeric antigen receptors against cd276 for the treatment of solid tumors
|
|
WO2025171238A1
(en)
|
2024-02-07 |
2025-08-14 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monoclonal antibodies that bind the juxta-membrane region of mesothelin and uses thereof
|