AU2003300718A1 - Process for preparing pyrrolo(2, 1-c) (1, 4) benzodiazepine hybrids - Google Patents

Process for preparing pyrrolo(2, 1-c) (1, 4) benzodiazepine hybrids

Info

Publication number
AU2003300718A1
AU2003300718A1 AU2003300718A AU2003300718A AU2003300718A1 AU 2003300718 A1 AU2003300718 A1 AU 2003300718A1 AU 2003300718 A AU2003300718 A AU 2003300718A AU 2003300718 A AU2003300718 A AU 2003300718A AU 2003300718 A1 AU2003300718 A1 AU 2003300718A1
Authority
AU
Australia
Prior art keywords
benzodiazepine hybrids
preparing pyrrolo
pyrrolo
preparing
benzodiazepine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003300718A
Inventor
Ahmed Kamal
Poddutoori Ramulu
Olepu Srinivas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Council of Scientific and Industrial Research CSIR
Original Assignee
Council of Scientific and Industrial Research CSIR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council of Scientific and Industrial Research CSIR filed Critical Council of Scientific and Industrial Research CSIR
Publication of AU2003300718A1 publication Critical patent/AU2003300718A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003300718A 2003-12-31 2003-12-31 Process for preparing pyrrolo(2, 1-c) (1, 4) benzodiazepine hybrids Abandoned AU2003300718A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2003/000462 WO2005063759A1 (en) 2003-12-31 2003-12-31 PROCESS FOR PREPARING PYRROLO[2, 1-c] [1, 4] BENZODIAZEPINE HYBRIDS

Publications (1)

Publication Number Publication Date
AU2003300718A1 true AU2003300718A1 (en) 2005-07-21

Family

ID=34717579

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003300718A Abandoned AU2003300718A1 (en) 2003-12-31 2003-12-31 Process for preparing pyrrolo(2, 1-c) (1, 4) benzodiazepine hybrids

Country Status (4)

Country Link
JP (1) JP4520411B2 (en)
AU (1) AU2003300718A1 (en)
GB (1) GB2424883B (en)
WO (1) WO2005063759A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5149193B2 (en) * 2005-11-10 2013-02-20 カウンスィル オブ サイエンティフィック アンド インダストリアル リサーチ Novel pyrrolo [2,1-c] [1,4] benzodiazepine hybrids and methods for their preparation
GB2459808B (en) * 2007-02-13 2011-09-14 Council Scient Ind Res Benzothiazole and benzoxazole linked pyrrolo [2,1-C] [1,4] benzodiazepine hybrids as novel antitumour agents and process for the preparation thereof
GB2469980B (en) * 2008-03-05 2012-02-22 Council Scient Ind Res Naphthalimide-benzimidazole hybrids as potential antitumour agents and process for the preparation thereof
WO2009113085A1 (en) * 2008-03-11 2009-09-17 Council Of Scientific & Industrial Research Novel benzimidazole linked pyrrolo[2,1-q[1,4] benzodiazepine hybrids as potential antitumour agents and process for the preparation thereof
US8372831B2 (en) 2008-03-26 2013-02-12 Council Of Scientific & Industrial Research Isoxazoline linked pyrrolo[2,1-c][1,4]benzodiazepine hybrids as potential anticancer agents and the process for preparation thereof
WO2010058414A1 (en) * 2008-11-19 2010-05-27 Council Of Scientific & Industrial Research Novel pyrroiol2,l-cu1.41benzodiazepine derivatives with dithiocarbamate side chains and process for the preparation thereof
CN113087763A (en) 2015-07-21 2021-07-09 伊缪诺金公司 Method for preparing cytotoxic benzodiazepine derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1193270E (en) * 1998-08-27 2003-10-31 Spirogen Ltd PYRROLOBENZODIAZEPINAS

Also Published As

Publication number Publication date
WO2005063759A1 (en) 2005-07-14
GB2424883B (en) 2008-10-22
JP2007528343A (en) 2007-10-11
GB2424883A (en) 2006-10-11
GB0614750D0 (en) 2006-09-06
JP4520411B2 (en) 2010-08-04

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase