AU2003300705A1 - C2-fluoro pyrrolo(2,1-c)(1,4)benzodiazepine dimers - Google Patents

C2-fluoro pyrrolo(2,1-c)(1,4)benzodiazepine dimers

Info

Publication number
AU2003300705A1
AU2003300705A1 AU2003300705A AU2003300705A AU2003300705A1 AU 2003300705 A1 AU2003300705 A1 AU 2003300705A1 AU 2003300705 A AU2003300705 A AU 2003300705A AU 2003300705 A AU2003300705 A AU 2003300705A AU 2003300705 A1 AU2003300705 A1 AU 2003300705A1
Authority
AU
Australia
Prior art keywords
benzodiazepine dimers
pyrrolo
fluoro
fluoro pyrrolo
benzodiazepine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003300705A
Inventor
Ahmed Kamal
Depatla Rajasekhar Reddy
Peram Surakattula Murali Mohan Reddy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Council of Scientific and Industrial Research CSIR
Original Assignee
Council of Scientific and Industrial Research CSIR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council of Scientific and Industrial Research CSIR filed Critical Council of Scientific and Industrial Research CSIR
Publication of AU2003300705A1 publication Critical patent/AU2003300705A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU2003300705A 2003-12-31 2003-12-31 C2-fluoro pyrrolo(2,1-c)(1,4)benzodiazepine dimers Abandoned AU2003300705A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2003/000448 WO2005063758A1 (en) 2003-12-31 2003-12-31 C2-FLUORO PYRROLO[2,1-c][1,4]BENZODIAZEPINE DIMERS

Publications (1)

Publication Number Publication Date
AU2003300705A1 true AU2003300705A1 (en) 2005-07-21

Family

ID=34717565

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003300705A Abandoned AU2003300705A1 (en) 2003-12-31 2003-12-31 C2-fluoro pyrrolo(2,1-c)(1,4)benzodiazepine dimers

Country Status (4)

Country Link
JP (1) JP4833663B2 (en)
AU (1) AU2003300705A1 (en)
GB (1) GB2425309B (en)
WO (1) WO2005063758A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007093873A1 (en) * 2006-02-13 2007-08-23 Council Of Scientific And Industrial Research Bis-pyrr0l0[2,l-c] [1, 4] benzodiazepine- anthraquinone conjugates as antitumour agents and a process for the preparation thereof
CA2645350C (en) * 2006-03-10 2014-09-09 Council Of Scientific And Industrial Research Novel bis-2-difluoro-pyrrolo[2,1-c][1,4]benzodiazepine dimmers
WO2009113084A1 (en) * 2008-03-11 2009-09-17 Council Of Scientific & Industrial Research C2-fluoro substituted piperazine linked pyrrolo[2,1-c][1,4] benzodiazepine dimers and a process for the preparation thereof
KR20180088445A (en) * 2015-12-04 2018-08-03 애브비 스템센트알엑스 엘엘씨 Novel anti-claudin antibodies and methods of use
CN117003875A (en) 2017-09-29 2023-11-07 第一三共株式会社 Antibody or functional fragment thereof, polynucleotide, expression vector, host cell, sugar chain reconstruction antibody, pharmaceutical composition and application

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9205051D0 (en) * 1992-03-09 1992-04-22 Cancer Res Campaign Tech Pyrrolobenzodiazepine derivatives,their preparation,and compositions containing them

Also Published As

Publication number Publication date
GB2425309B (en) 2008-07-09
JP2007518671A (en) 2007-07-12
GB0614749D0 (en) 2006-09-06
JP4833663B2 (en) 2011-12-07
GB2425309A (en) 2006-10-25
WO2005063758A1 (en) 2005-07-14

Similar Documents

Publication Publication Date Title
AP2002002695A0 (en) Pyrrolo Ä2,3-dÜpyrimidine compounds
AU2003248588A1 (en) Substituted pyrrolopyridines
AU2003283653A1 (en) Solution search
AU2003270792A1 (en) Desalinization still
AU2003242600A1 (en) Solid mycoctoxin carriers
AU2002308154A1 (en) Triazolopyrimidines
AU2003294726A1 (en) Window-winding arrangement
AU2003277022A1 (en) Artemisinin-derived trioxane dimers
AU2002950433A0 (en) Recreation range
AU2003229657A1 (en) Triazolopyrimidines
AU2003214931A1 (en) Rack
AU2003272666A1 (en) Single shelf router
AU2003300705A1 (en) C2-fluoro pyrrolo(2,1-c)(1,4)benzodiazepine dimers
AU2003300718A1 (en) Process for preparing pyrrolo(2, 1-c) (1, 4) benzodiazepine hybrids
AU2003244770A1 (en) Moulded components
AU2003244788A1 (en) Polymeric based complex
AU2003289315A1 (en) Aromatic compounds
AU2003300720A1 (en) C-8 linked pyrrolo(2,1-c)(1,4)benzodiazepine-acridone/acridine hybrids
AU2003285408A1 (en) Impression tray set
AU2003227258A1 (en) Benzodiazepine derivative
AU2003234859A1 (en) Description
AU2003243065A1 (en) Grin-lens arrangement
AU2003292595A1 (en) Benzodiazepine derivative
AU2003267599A1 (en) Multiple component container system
AU2003235537A1 (en) Amber-climatic complex

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase