GB0614750D0 - Process for preparing pyrrolo[2, 1-c] [1,4] benzodiazepine hybrids - Google Patents
Process for preparing pyrrolo[2, 1-c] [1,4] benzodiazepine hybridsInfo
- Publication number
- GB0614750D0 GB0614750D0 GBGB0614750.8A GB0614750A GB0614750D0 GB 0614750 D0 GB0614750 D0 GB 0614750D0 GB 0614750 A GB0614750 A GB 0614750A GB 0614750 D0 GB0614750 D0 GB 0614750D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- benzodiazepine hybrids
- preparing pyrrolo
- pyrrolo
- preparing
- benzodiazepine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IN2003/000462 WO2005063759A1 (en) | 2003-12-31 | 2003-12-31 | PROCESS FOR PREPARING PYRROLO[2, 1-c] [1, 4] BENZODIAZEPINE HYBRIDS |
Publications (3)
Publication Number | Publication Date |
---|---|
GB0614750D0 true GB0614750D0 (en) | 2006-09-06 |
GB2424883A GB2424883A (en) | 2006-10-11 |
GB2424883B GB2424883B (en) | 2008-10-22 |
Family
ID=34717579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB0614750A Expired - Fee Related GB2424883B (en) | 2003-12-31 | 2003-12-31 | Process for preparing pyrrolo[2, 1-c] [1,4] benzodiazepine hybrids |
Country Status (4)
Country | Link |
---|---|
JP (1) | JP4520411B2 (en) |
AU (1) | AU2003300718A1 (en) |
GB (1) | GB2424883B (en) |
WO (1) | WO2005063759A1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007054954A1 (en) * | 2005-11-10 | 2007-05-18 | Council Of Scientific & Industrial Research | A novel pyrrolo[2,1-c][1,4]benzodiazepine hybrid and a process for the preparation thereof |
US8063204B2 (en) | 2007-02-13 | 2011-11-22 | Council Of Scientific & Industrial Research | Benzothiazole and benzoxazole linked pyrrolo[2,1-c] [1, 4] benzodiazepine hybrids as novel antitumour agents and process for the preparation thereof |
US8288387B2 (en) * | 2008-03-05 | 2012-10-16 | Council Of Scientific & Industrial Research | Napthalimide-benzimidazole hybrids as potential antitumor agents and process for the preparation thereof |
EP2257547B1 (en) | 2008-03-11 | 2015-08-05 | Council Of Scientific & Industrial Research | Novel benzimidazole linked pyrroloý2,1-qý1,4¨benzodiazepine hybrids as potential antitumour agents and process for the preparation thereof |
WO2009118748A1 (en) * | 2008-03-26 | 2009-10-01 | Council Of Scientific & Industrial Research | Isoxazoline linked pyrrolo[2,1-c[1,4]benzodiazepine hybrids as potential anticancer agents and the process for preparation thereof |
WO2010058414A1 (en) * | 2008-11-19 | 2010-05-27 | Council Of Scientific & Industrial Research | Novel pyrroiol2,l-cu1.41benzodiazepine derivatives with dithiocarbamate side chains and process for the preparation thereof |
US10081640B2 (en) | 2015-07-21 | 2018-09-25 | Immunogen, Inc. | Methods of preparing cytotoxic benzodiazepine derivatives |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1193270B1 (en) * | 1998-08-27 | 2003-05-14 | Spirogen Limited | Pyrrolobenzodiazepines |
-
2003
- 2003-12-31 AU AU2003300718A patent/AU2003300718A1/en not_active Abandoned
- 2003-12-31 WO PCT/IN2003/000462 patent/WO2005063759A1/en active Application Filing
- 2003-12-31 GB GB0614750A patent/GB2424883B/en not_active Expired - Fee Related
- 2003-12-31 JP JP2005512761A patent/JP4520411B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2005063759A1 (en) | 2005-07-14 |
AU2003300718A1 (en) | 2005-07-21 |
GB2424883A (en) | 2006-10-11 |
GB2424883B (en) | 2008-10-22 |
JP4520411B2 (en) | 2010-08-04 |
JP2007528343A (en) | 2007-10-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20171231 |