DE69930328D1 - Dimere Pyrrolobenzodiazepine - Google Patents

Dimere Pyrrolobenzodiazepine

Info

Publication number
DE69930328D1
DE69930328D1 DE69930328T DE69930328T DE69930328D1 DE 69930328 D1 DE69930328 D1 DE 69930328D1 DE 69930328 T DE69930328 T DE 69930328T DE 69930328 T DE69930328 T DE 69930328T DE 69930328 D1 DE69930328 D1 DE 69930328D1
Authority
DE
Germany
Prior art keywords
pyrrolobenzodiazepines
dimer
dimer pyrrolobenzodiazepines
pharmaceutical
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69930328T
Other languages
English (en)
Other versions
DE69930328T2 (de
Inventor
Edwin Thurston
Wilson Howard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADC Products UK Ltd
Original Assignee
ADC Products UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9818733.9A external-priority patent/GB9818733D0/en
Priority claimed from GBGB9901929.1A external-priority patent/GB9901929D0/en
Application filed by ADC Products UK Ltd filed Critical ADC Products UK Ltd
Publication of DE69930328D1 publication Critical patent/DE69930328D1/de
Application granted granted Critical
Publication of DE69930328T2 publication Critical patent/DE69930328T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrrole Compounds (AREA)
DE69930328T 1998-08-27 1999-08-27 Dimere Pyrrolobenzodiazepine Expired - Lifetime DE69930328T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
HN9818733 1998-08-27
GBGB9818733.9A GB9818733D0 (en) 1998-08-27 1998-08-27 Compounds
GB9901929 1999-01-28
GBGB9901929.1A GB9901929D0 (en) 1999-01-28 1999-01-28 Compounds

Publications (2)

Publication Number Publication Date
DE69930328D1 true DE69930328D1 (de) 2006-05-11
DE69930328T2 DE69930328T2 (de) 2006-12-14

Family

ID=26314276

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69925133T Expired - Lifetime DE69925133T2 (de) 1998-08-27 1999-08-27 Pyrrolobenzodiazepine
DE69930328T Expired - Lifetime DE69930328T2 (de) 1998-08-27 1999-08-27 Dimere Pyrrolobenzodiazepine
DE69907977T Expired - Lifetime DE69907977T2 (de) 1998-08-27 1999-08-27 Pyrrolobenzodiazepine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69925133T Expired - Lifetime DE69925133T2 (de) 1998-08-27 1999-08-27 Pyrrolobenzodiazepine

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69907977T Expired - Lifetime DE69907977T2 (de) 1998-08-27 1999-08-27 Pyrrolobenzodiazepine

Country Status (12)

Country Link
US (3) US7049311B1 (de)
EP (3) EP1413582B1 (de)
JP (1) JP4824165B2 (de)
AT (3) ATE294803T1 (de)
AU (1) AU757510C (de)
CA (1) CA2341471C (de)
DE (3) DE69925133T2 (de)
DK (3) DK1413582T3 (de)
ES (3) ES2260570T3 (de)
NZ (1) NZ510493A (de)
PT (3) PT1109812E (de)
WO (1) WO2000012508A2 (de)

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* Cited by examiner, † Cited by third party
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