ATE203910T1 - Präparat mit verzörgerter wirkstoffabgabe - Google Patents

Präparat mit verzörgerter wirkstoffabgabe

Info

Publication number
ATE203910T1
ATE203910T1 AT93309681T AT93309681T ATE203910T1 AT E203910 T1 ATE203910 T1 AT E203910T1 AT 93309681 T AT93309681 T AT 93309681T AT 93309681 T AT93309681 T AT 93309681T AT E203910 T1 ATE203910 T1 AT E203910T1
Authority
AT
Austria
Prior art keywords
group
formula
amino
sustained
chem
Prior art date
Application number
AT93309681T
Other languages
English (en)
Inventor
Shigeru Kamei
Yasutaka Igari
Yasuaki Ogawa
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE203910T1 publication Critical patent/ATE203910T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AT93309681T 1992-12-07 1993-12-03 Präparat mit verzörgerter wirkstoffabgabe ATE203910T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP32707092 1992-12-07
JP1897893 1993-02-05
JP14513493 1993-06-16

Publications (1)

Publication Number Publication Date
ATE203910T1 true ATE203910T1 (de) 2001-08-15

Family

ID=27282444

Family Applications (2)

Application Number Title Priority Date Filing Date
AT93309681T ATE203910T1 (de) 1992-12-07 1993-12-03 Präparat mit verzörgerter wirkstoffabgabe
AT00203850T ATE295733T1 (de) 1992-12-07 1993-12-03 Leuprorelinpräparat mit verzögerter wirkstoffabgabe

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT00203850T ATE295733T1 (de) 1992-12-07 1993-12-03 Leuprorelinpräparat mit verzögerter wirkstoffabgabe

Country Status (24)

Country Link
US (7) US5480868A (de)
EP (2) EP0601799B1 (de)
JP (1) JP3725906B2 (de)
KR (2) KR100305951B1 (de)
CN (2) CN1099893C (de)
AT (2) ATE203910T1 (de)
AU (1) AU669939B2 (de)
CA (1) CA2110730C (de)
DE (2) DE69333817T2 (de)
DK (2) DK0601799T3 (de)
EE (1) EE03117B1 (de)
ES (2) ES2158856T3 (de)
FI (2) FI935471A (de)
GE (1) GEP19991600B (de)
GR (1) GR3037085T3 (de)
HK (1) HK1037519A1 (de)
LV (1) LV10927B (de)
MX (1) MX9307686A (de)
NO (1) NO310704B1 (de)
NZ (1) NZ250349A (de)
PT (2) PT1088555E (de)
SG (1) SG46283A1 (de)
TW (1) TW333456B (de)
WO (1) WO1994013317A1 (de)

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DE69330547D1 (de) 2001-09-13
EP0601799A1 (de) 1994-06-15
US5480868A (en) 1996-01-02
DK0601799T3 (da) 2001-10-01
US20030039698A1 (en) 2003-02-27
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