ZA905742B - (r-(r*r*))1-2-(4-fluorophenyl)beta-dihydroxy-5-(1-methyle-thyl-3-phenyl-4-((phenylamino)carbonyl)-1h-pyrrole-1-heptanoic acid,its lactone form and salts thereof - Google Patents

(r-(r*r*))1-2-(4-fluorophenyl)beta-dihydroxy-5-(1-methyle-thyl-3-phenyl-4-((phenylamino)carbonyl)-1h-pyrrole-1-heptanoic acid,its lactone form and salts thereof

Info

Publication number
ZA905742B
ZA905742B ZA905742A ZA905742A ZA905742B ZA 905742 B ZA905742 B ZA 905742B ZA 905742 A ZA905742 A ZA 905742A ZA 905742 A ZA905742 A ZA 905742A ZA 905742 B ZA905742 B ZA 905742B
Authority
ZA
South Africa
Prior art keywords
fluorophenyl
pyrrole
phenylamino
dihydroxy
carbonyl
Prior art date
Application number
ZA905742A
Other languages
English (en)
Inventor
Bruce David Roth
David Roth Bruce
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23516372&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA905742(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ZA905742B publication Critical patent/ZA905742B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA905742A 1989-07-21 1990-07-20 (r-(r*r*))1-2-(4-fluorophenyl)beta-dihydroxy-5-(1-methyle-thyl-3-phenyl-4-((phenylamino)carbonyl)-1h-pyrrole-1-heptanoic acid,its lactone form and salts thereof ZA905742B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38418789A 1989-07-21 1989-07-21

Publications (1)

Publication Number Publication Date
ZA905742B true ZA905742B (en) 1992-03-25

Family

ID=23516372

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA905742A ZA905742B (en) 1989-07-21 1990-07-20 (r-(r*r*))1-2-(4-fluorophenyl)beta-dihydroxy-5-(1-methyle-thyl-3-phenyl-4-((phenylamino)carbonyl)-1h-pyrrole-1-heptanoic acid,its lactone form and salts thereof

Country Status (20)

Country Link
US (2) US5273995A (de)
EP (2) EP1061073B1 (de)
JP (6) JP3506336B2 (de)
KR (1) KR0167101B1 (de)
AT (2) ATE207896T1 (de)
AU (1) AU628198B2 (de)
CA (1) CA2021546C (de)
CY (1) CY2357B1 (de)
DE (3) DE1061073T1 (de)
DK (2) DK1061073T3 (de)
ES (2) ES2167306T3 (de)
FI (1) FI94339C (de)
GE (1) GEP20043167B (de)
GR (1) GR20010300002T1 (de)
IE (1) IE902659A1 (de)
NO (1) NO174709C (de)
NZ (1) NZ234576A (de)
PT (1) PT94778B (de)
SG (1) SG46495A1 (de)
ZA (1) ZA905742B (de)

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