TR199802426T2 - Taksus t�r�n�n h�cre k�lt�rleriyle taksanlar�n artt�r�lm�� �retimi. - Google Patents
Taksus t�r�n�n h�cre k�lt�rleriyle taksanlar�n artt�r�lm�� �retimi.Info
- Publication number
- TR199802426T2 TR199802426T2 TR1998/02426T TR9802426T TR199802426T2 TR 199802426 T2 TR199802426 T2 TR 199802426T2 TR 1998/02426 T TR1998/02426 T TR 1998/02426T TR 9802426 T TR9802426 T TR 9802426T TR 199802426 T2 TR199802426 T2 TR 199802426T2
- Authority
- TR
- Turkey
- Prior art keywords
- taxus
- taxol
- efficiency
- species
- enhancing agents
- Prior art date
Links
- 241001116500 Taxus Species 0.000 abstract 3
- OVMSOCFBDVBLFW-VHLOTGQHSA-N 5beta,20-epoxy-1,7beta,13alpha-trihydroxy-9-oxotax-11-ene-2alpha,4alpha,10beta-triyl 4,10-diacetate 2-benzoate Chemical compound O([C@@H]1[C@@]2(C[C@H](O)C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)O)C(=O)C1=CC=CC=C1 OVMSOCFBDVBLFW-VHLOTGQHSA-N 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 230000002708 enhancing effect Effects 0.000 abstract 2
- ZNJFBWYDHIGLCU-HWKXXFMVSA-N jasmonic acid Chemical compound CC\C=C/C[C@@H]1[C@@H](CC(O)=O)CCC1=O ZNJFBWYDHIGLCU-HWKXXFMVSA-N 0.000 abstract 2
- GJAIAEVUUHUHTE-OWOJBTEDSA-N 6315-90-8 Chemical compound C1=C([N+]([O-])=O)C(/C=C/C(=O)O)=CC2=C1OCO2 GJAIAEVUUHUHTE-OWOJBTEDSA-N 0.000 abstract 1
- 229930192334 Auxin Natural products 0.000 abstract 1
- 229930012538 Paclitaxel Natural products 0.000 abstract 1
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 abstract 1
- 229940123237 Taxane Drugs 0.000 abstract 1
- 239000002363 auxin Substances 0.000 abstract 1
- 229930014667 baccatin III Natural products 0.000 abstract 1
- 238000004113 cell culture Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003630 growth substance Substances 0.000 abstract 1
- SEOVTRFCIGRIMH-UHFFFAOYSA-N indole-3-acetic acid Chemical compound C1=CC=C2C(CC(=O)O)=CNC2=C1 SEOVTRFCIGRIMH-UHFFFAOYSA-N 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- ZNJFBWYDHIGLCU-UHFFFAOYSA-N jasmonic acid Natural products CCC=CCC1C(CC(O)=O)CCC1=O ZNJFBWYDHIGLCU-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000004702 methyl esters Chemical class 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 229960001592 paclitaxel Drugs 0.000 abstract 1
- 229930015704 phenylpropanoid Natural products 0.000 abstract 1
- 150000002995 phenylpropanoid derivatives Chemical class 0.000 abstract 1
- MCJGNVYPOGVAJF-UHFFFAOYSA-N quinolin-8-ol Chemical compound C1=CN=C2C(O)=CC=CC2=C1 MCJGNVYPOGVAJF-UHFFFAOYSA-N 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0025—Culture media for plant cell or plant tissue culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/04—Plant cells or tissues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P15/00—Preparation of compounds containing at least three condensed carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65303696A | 1996-05-24 | 1996-05-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199802426T2 true TR199802426T2 (xx) | 2001-01-22 |
Family
ID=24619244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR1998/02426T TR199802426T2 (xx) | 1996-05-24 | 1997-05-27 | Taksus t�r�n�n h�cre k�lt�rleriyle taksanlar�n artt�r�lm�� �retimi. |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8338143B2 (enExample) |
| EP (3) | EP1398384A1 (enExample) |
| JP (5) | JP4047929B2 (enExample) |
| KR (7) | KR100897457B1 (enExample) |
| AT (1) | ATE315097T1 (enExample) |
| AU (1) | AU727425B2 (enExample) |
| BR (1) | BR9709361B1 (enExample) |
| CA (2) | CA2256357C (enExample) |
| DE (1) | DE69735059T2 (enExample) |
| DK (1) | DK0954596T3 (enExample) |
| ES (1) | ES2256887T3 (enExample) |
| HU (2) | HU223267B1 (enExample) |
| IL (1) | IL127062A (enExample) |
| PT (1) | PT954596E (enExample) |
| TR (1) | TR199802426T2 (enExample) |
| WO (1) | WO1997044476A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7264951B1 (en) | 1992-02-20 | 2007-09-04 | Phyton, Inc. | Enhanced production of taxol and taxanes by cell cultures of Taxus species |
| TR199802426T2 (xx) * | 1996-05-24 | 2001-01-22 | Phyton, Inc.. | Taksus t�r�n�n h�cre k�lt�rleriyle taksanlar�n artt�r�lm�� �retimi. |
| KR100287465B1 (ko) * | 1997-06-25 | 2001-05-02 | 나까니시 히로유끼 | 탁산형 디테르펜의 제조방법 |
| TW200304947A (en) * | 2002-02-08 | 2003-10-16 | Bristol Myers Squibb Co | Compositions and methods for latering biosynthesis of taxanes and taxane-related compounds |
| US8936940B2 (en) | 2005-06-03 | 2015-01-20 | Samyang Biopharmaceuticals Corporation | Mass production of secondary metabolite in plant cell culture by treatment of saccharide mixture in medium |
| US8053238B2 (en) | 2005-10-31 | 2011-11-08 | Unhwa Corporation | Isolated population of plant single cells and method of preparing the same |
| RU2398874C2 (ru) * | 2005-10-31 | 2010-09-10 | Юнхва | Клеточные клоны камбия, способ их выделения и консервации |
| KR101064518B1 (ko) | 2007-09-21 | 2011-09-19 | 주식회사 운화 | 저장근을 가지는 초본식물의 형성층 유래 식물줄기세포주 및 이의 분리방법 |
| KR101100867B1 (ko) * | 2008-05-14 | 2012-01-02 | 주식회사 운화 | 주목의 형성층 또는 전형성층 유래 식물줄기세포주를 유효성분으로 함유하는 항산화, 항염증 또는 항노화용 조성물 |
| CA2766050C (en) | 2009-06-18 | 2018-09-25 | Phyton Holdings, Llc | Production of alkaloids by liliaceae cell culture |
| FR2952072B1 (fr) * | 2009-11-05 | 2013-09-27 | Pf Medicament | Procede de production de triptolide |
| WO2013164834A1 (en) * | 2012-05-04 | 2013-11-07 | Phyto Biotech Pvt. Ltd. | Cost-effective process for commercial production of paclitaxel |
| CN103570647A (zh) * | 2013-11-06 | 2014-02-12 | 湖南农业大学 | 从红豆杉细胞培养液中制备高纯度紫杉醇的方法 |
| EP3077523B1 (en) | 2013-12-02 | 2020-05-06 | Phyton Holdings, LLC | Production of thapsigargins by thapsia cell suspension culture |
| US10058542B1 (en) | 2014-09-12 | 2018-08-28 | Thioredoxin Systems Ab | Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith |
| ES2770769T3 (es) | 2015-03-20 | 2020-07-03 | Phyton Holdings Llc | Producción de ingenol, ésteres de ingenol y/o derivados de tiglian-3-ona mediante cultivos en suspensión de células vegetales de Euphorbiaceae |
| CN105349592B (zh) * | 2015-12-09 | 2018-11-27 | 天津艾赛博生物技术有限公司 | 代谢互补的植物细胞系混种培养生产次级代谢产物的方法 |
| CN106636242A (zh) * | 2016-12-20 | 2017-05-10 | 天津艾赛博生物技术有限公司 | 一种红豆杉细胞长期培养生产紫杉烷的调控方法 |
| JP7359527B2 (ja) * | 2017-05-31 | 2023-10-11 | トヨタ自動車株式会社 | 電池搭載構造 |
| AU2021318553A1 (en) * | 2020-07-28 | 2023-03-23 | Impello Biosciences Inc. | Methods and compositions for altering secondary metabolites in plants |
| CN113416689B (zh) * | 2021-08-04 | 2023-01-10 | 海南鑫开源医药科技有限公司 | 一种利用植物细胞发酵技术生产高丽槐素的方法 |
| CN115948494B (zh) * | 2022-09-12 | 2024-07-16 | 昆明理工大学 | 一种利用三七细胞合成齐墩果烷型皂苷的方法 |
| WO2025058703A1 (en) * | 2023-09-13 | 2025-03-20 | Bedoukian Research, Inc | Method of controlling or reducing senescencein plants and seeds |
Family Cites Families (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3270112D1 (en) | 1981-08-11 | 1986-04-30 | Mitsui Petrochemical Ind | Method for producing secondary metabolites of plants |
| WO1986002463A1 (fr) | 1984-10-19 | 1986-04-24 | Alain Zarudiansky | Systeme de lunettes |
| JPH0833258B2 (ja) | 1987-10-09 | 1996-03-29 | 三洋電機株式会社 | 吸収冷凍装置 |
| DE3801023A1 (de) | 1988-01-13 | 1989-07-27 | Schering Ag | Verfahren zur steigerung von enzym-aktivitaeten und der syntheseleistung von organismen |
| EP0378921A3 (en) | 1988-12-21 | 1990-09-19 | Idaho Research Foundation, Inc. | Enhancement of plant metabolite production by timed elicitation |
| US5019504A (en) * | 1989-03-23 | 1991-05-28 | The United States Of America As Represented By The Secretary Of Agriculture | Production of taxol or taxol-like compounds in cell culture |
| US5334529A (en) | 1989-06-27 | 1994-08-02 | Escagenetics Corporation | Stably transformed coffee plant cells and plantlets |
| US5015744A (en) | 1989-11-14 | 1991-05-14 | Florida State University | Method for preparation of taxol using an oxazinone |
| EP0532650B1 (en) | 1990-05-25 | 1996-09-11 | Washington State University Research Foundation, Inc. | Method of inducing plant defense mechanisms |
| DE69216003D1 (de) | 1991-02-12 | 1997-01-30 | Nippon Steel Corp | Verfahren zur herstellung von taxol mittels taxusspezies-zellkultur |
| US5244775A (en) * | 1991-03-20 | 1993-09-14 | Hitachi, Ltd. | Method of manufacturing an optical disc |
| AU1888792A (en) | 1991-04-19 | 1992-11-17 | University Of Mississippi, The | Methods and compositions for isolating taxanes |
| US5248625A (en) | 1991-06-06 | 1993-09-28 | Lsi Logic Corporation | Techniques for forming isolation structures |
| EP0555485A4 (en) | 1991-07-17 | 1993-11-03 | Nippon Steel Corporation | Antitumor compound nsc-lsc1 and production thereof |
| US5344775A (en) | 1991-11-15 | 1994-09-06 | Escagenetics Corporation | Synthesis of taxanes in culture using pseudocalluscells |
| US5407816A (en) | 1992-02-20 | 1995-04-18 | Phyton Catalytic, Inc. | Enhanced production of taxol and taxanes by cell cultures of taxus species |
| US5445809A (en) | 1992-03-03 | 1995-08-29 | Research And Development Institute At Montana State University | Production of taxol from the yew tree |
| US5451392A (en) | 1992-03-03 | 1995-09-19 | The Research And Development Institute At Montana State University | Production of taxol |
| JPH05244971A (ja) | 1992-03-06 | 1993-09-24 | Nippon Oil Co Ltd | タキサン類化合物の製造方法 |
| JPH07508163A (ja) | 1992-04-01 | 1995-09-14 | ユニオン・キャンプ・コーポレーション | イチイ属の体細胞胚形成の誘導及びそれからのタキサン環含有アルカロイドの生産 |
| US5850032A (en) | 1992-04-01 | 1998-12-15 | Union Camp Corporation | Method for production of plant biological products in precocious neomorphic embryoids |
| CA2092849C (en) | 1992-04-07 | 2003-11-18 | Paul M. Cino | Callus cell induction and the preparation of taxanes |
| US5322779A (en) | 1992-04-16 | 1994-06-21 | The Research And Development Institute, Inc. At Montana State University | Taxol production by taxomyces andreanae |
| EP0642586A4 (en) | 1992-05-21 | 1995-11-29 | Penn State Res Found | CULTURAL -i (TAXUS) FABRIC AS A SOURCE OF TAXOL, RELATED TAXANS AND OTHER NEW ANTI-TUMOR / ANTI-VIRAL SUBSTANCES (01/20/94). |
| JP2967532B2 (ja) | 1992-06-11 | 1999-10-25 | 日石三菱株式会社 | タキサン類化合物の製造方法 |
| US5279953A (en) | 1992-06-24 | 1994-01-18 | Esca Genetics Corporation | In vivo production of taxanes |
| JP3162217B2 (ja) | 1992-12-24 | 2001-04-25 | 三井化学株式会社 | タキサン型ジテルペンの製造方法 |
| JP3144947B2 (ja) | 1993-04-08 | 2001-03-12 | 三井化学株式会社 | タキサン型ジテルペンの製造方法 |
| JPH06296493A (ja) | 1993-04-14 | 1994-10-25 | Nippon Steel Corp | タキソールの生産方法 |
| KR950005081B1 (ko) | 1993-07-06 | 1995-05-18 | 산림청임목육종연구소 | 주목 종자의 씨눈 유래의 체세포배 및 체세포배성세포 혹은 그 배양배지로부터 택솔(Taxol) 및 그 유도체를 생산하는 방법 |
| JP3434892B2 (ja) | 1994-06-28 | 2003-08-11 | 三井化学株式会社 | タキサン型ジテルペンの製造方法 |
| JPH0856680A (ja) * | 1994-08-25 | 1996-03-05 | Mitsui Petrochem Ind Ltd | タキサン型ジテルペンの製造方法 |
| JPH07308197A (ja) | 1994-05-18 | 1995-11-28 | Mitsui Petrochem Ind Ltd | タキサン型ジテルペンの製造方法 |
| JPH07308196A (ja) | 1994-05-18 | 1995-11-28 | Mitsui Petrochem Ind Ltd | タキサン型ジテルペンの製造方法 |
| KR0172606B1 (ko) | 1993-11-15 | 1999-02-01 | 고다 시게노리 | 탁산형 디테르펜의 제조방법 |
| JP3488492B2 (ja) | 1993-11-15 | 2004-01-19 | 三井化学株式会社 | タキサン型ジテルペン高産生培養細胞の取得方法 |
| JPH08116981A (ja) | 1994-10-18 | 1996-05-14 | Mitsui Petrochem Ind Ltd | タキサン型ジテルペンの製造方法 |
| JPH0856681A (ja) | 1994-08-25 | 1996-03-05 | Mitsui Petrochem Ind Ltd | タキサン型ジテルペンの製造方法 |
| JP2967034B2 (ja) | 1994-03-07 | 1999-10-25 | 三井化学株式会社 | タキサン型ジテルペンの製造方法 |
| JPH07255495A (ja) | 1994-03-28 | 1995-10-09 | Ishikawajima Harima Heavy Ind Co Ltd | タキソールの製造方法 |
| US5547866A (en) | 1994-07-20 | 1996-08-20 | The Regents Of The University Of California | Taxane production in haploid-derived cell cultures |
| JPH0870880A (ja) | 1994-09-05 | 1996-03-19 | Osaka Organic Chem Ind Ltd | タキソールの培養生産法 |
| JPH08163991A (ja) | 1994-12-15 | 1996-06-25 | Mitsui Petrochem Ind Ltd | タキサン型ジテルペンの製造方法 |
| CA2163614C (en) | 1994-11-25 | 2002-12-31 | Yukihito Yukimune | Method of producing a taxane-type diterpene |
| JP3549594B2 (ja) | 1994-11-25 | 2004-08-04 | 三井化学株式会社 | タキサン型ジテルペンの製造方法 |
| JPH08149984A (ja) | 1994-11-30 | 1996-06-11 | Mitsui Petrochem Ind Ltd | タキサン型ジテルペンの製造方法 |
| JP3746550B2 (ja) | 1994-12-05 | 2006-02-15 | 三井化学株式会社 | タキサン型ジテルペンの製造方法 |
| JPH08154693A (ja) | 1994-12-05 | 1996-06-18 | Mitsui Petrochem Ind Ltd | タキサン型ジテルペンの製造方法 |
| JPH08205881A (ja) * | 1994-12-05 | 1996-08-13 | Mitsui Petrochem Ind Ltd | タキサン型ジテルペンの製造方法 |
| JP3019736B2 (ja) | 1994-12-07 | 2000-03-13 | 三井化学株式会社 | タキサン型ジテルペンの製造方法 |
| JPH08198863A (ja) * | 1995-01-25 | 1996-08-06 | Mitsui Petrochem Ind Ltd | タキサン型ジテルペンの製造方法 |
| US5620875A (en) | 1995-02-17 | 1997-04-15 | University Of Portland | Transfer of taxol from yew tree cuttings into a culture medium over time |
| US6248572B1 (en) | 1995-04-27 | 2001-06-19 | Samyang, Genex, Corporation | Production of taxol from taxus plant cell culture adding silver nitrate |
| KR960037826A (ko) | 1995-04-27 | 1996-11-19 | 김경환 | 택서스속 식물세포의 반연속식 배양방법 |
| EP0774010B1 (en) | 1995-04-29 | 2001-09-26 | Samyang Genex Co., Ltd. | A method for mass production of taxol from taxus genus plant |
| JPH08298993A (ja) | 1995-05-02 | 1996-11-19 | Nippon Steel Corp | イチイの組織培養によるタキサン化合物の製造法 |
| US5965438A (en) | 1995-06-07 | 1999-10-12 | Phyton, Inc. | Cryopreservation of plant cells |
| JPH0928392A (ja) | 1995-07-17 | 1997-02-04 | Mitsui Petrochem Ind Ltd | タキサン型ジテルペンの製造方法 |
| JPH0956387A (ja) | 1995-08-22 | 1997-03-04 | Mitsui Petrochem Ind Ltd | タキサン型ジテルペンの製造方法 |
| US5670663A (en) | 1996-02-14 | 1997-09-23 | Regents Of The University Of California | Recovery of taxanes from conifers |
| TR199802426T2 (xx) * | 1996-05-24 | 2001-01-22 | Phyton, Inc.. | Taksus t�r�n�n h�cre k�lt�rleriyle taksanlar�n artt�r�lm�� �retimi. |
| JPH1042888A (ja) | 1996-07-30 | 1998-02-17 | Jumoku Seiri Kinousei Butsushitsu Gijutsu Kenkyu Kumiai | タキソールの培養生産方法 |
| JPH1052295A (ja) | 1996-08-09 | 1998-02-24 | Nippon Oil Co Ltd | タキサン類化合物の製造方法（ｉｉ） |
| JPH1052294A (ja) | 1996-08-09 | 1998-02-24 | Nippon Oil Co Ltd | タキサン類化合物の製造方法（ｉ） |
| JPH1052296A (ja) | 1996-08-09 | 1998-02-24 | Nippon Oil Co Ltd | タキサン類化合物の製造方法（ｉｉｉ） |
| AU727388B2 (en) | 1997-02-19 | 2000-12-14 | Phytobiotech Inc. | Method for increasing the growth of plant cell cultures |
| KR100287465B1 (ko) | 1997-06-25 | 2001-05-02 | 나까니시 히로유끼 | 탁산형 디테르펜의 제조방법 |
| JPH1146782A (ja) | 1997-08-05 | 1999-02-23 | Mitsui Chem Inc | ラジカル発生剤処理による植物二次代謝産物の生産促進方法 |
| US6030818A (en) | 1997-12-22 | 2000-02-29 | Bcm Developpement, Inc. | Bacterial mass production of taxanes and paclitaxel |
| JP3897267B2 (ja) | 1998-03-26 | 2007-03-22 | 三井化学株式会社 | タキサン型ジテルペンの製造方法 |
| JP2000106893A (ja) | 1998-10-06 | 2000-04-18 | Kobe Tennenbutsu Kagaku Kk | タキサン型ジテルペン類の製造方法 |
| JP3815919B2 (ja) | 1999-05-26 | 2006-08-30 | 三井化学株式会社 | タキサン型ジテルペンの製造方法 |
| US6365407B1 (en) | 2001-03-05 | 2002-04-02 | Council Of Scientific & Industrial Research | Culture medium composition useful for induction and proliferation of Taxus calli |
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1997
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- 1997-05-27 KR KR1020107012491A patent/KR20100070389A/ko not_active Ceased
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2008
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