ATE373715T1 - Isoprenoid biosynthese - Google Patents

Isoprenoid biosynthese

Info

Publication number
ATE373715T1
ATE373715T1 AT00949452T AT00949452T ATE373715T1 AT E373715 T1 ATE373715 T1 AT E373715T1 AT 00949452 T AT00949452 T AT 00949452T AT 00949452 T AT00949452 T AT 00949452T AT E373715 T1 ATE373715 T1 AT E373715T1
Authority
AT
Austria
Prior art keywords
inhibitors
relates
well
present
plant
Prior art date
Application number
AT00949452T
Other languages
English (en)
Inventor
Adelbert Bacher
Meinhart H Zenk
Wolfgang Eisenreich
Monika Fellermeier
Markus Fischer
Stefan Hecht
Stefan Herz
Klaus Kis
Holger Luettgen
Felix Rohdich
Silvia Sagner
Christoph Schuhr
Juraithip Wungsintaweekul
Original Assignee
Adelbert Bacher
Meinhart H Zenk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10020996A external-priority patent/DE10020996A1/de
Application filed by Adelbert Bacher, Meinhart H Zenk filed Critical Adelbert Bacher
Application granted granted Critical
Publication of ATE373715T1 publication Critical patent/ATE373715T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1229Phosphotransferases with a phosphate group as acceptor (2.7.4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
AT00949452T 1999-08-04 2000-08-03 Isoprenoid biosynthese ATE373715T1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE19936663 1999-08-04
DE19945174 1999-09-21
DE19945175 1999-09-21
DE19948887 1999-10-11
DE19953309 1999-11-05
DE10020996A DE10020996A1 (de) 1999-08-04 2000-04-28 Isoprenoidbiosynthese

Publications (1)

Publication Number Publication Date
ATE373715T1 true ATE373715T1 (de) 2007-10-15

Family

ID=27544993

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00949452T ATE373715T1 (de) 1999-08-04 2000-08-03 Isoprenoid biosynthese

Country Status (6)

Country Link
US (2) US7122331B1 (de)
EP (1) EP1198575B1 (de)
AT (1) ATE373715T1 (de)
AU (1) AU6280300A (de)
DE (1) DE60036477T2 (de)
WO (1) WO2001011055A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10027821A1 (de) 2000-06-05 2001-12-06 Adelbert Bacher Der Mevalonat-unabhängige Isoprenoidbiosyntheseweg
US6660507B2 (en) 2000-09-01 2003-12-09 E. I. Du Pont De Nemours And Company Genes involved in isoprenoid compound production
US7736881B2 (en) 2000-10-13 2010-06-15 University Of Utah Research Foundation Antibacterial and herbicidal compounds and system for screening the same
DE10201458A1 (de) * 2001-04-11 2002-10-17 Adelbert Bacher Intermediate und Enzyme des Mevalonat-unabhängigen Isoprenoidbiosyntheseweg
AU2008290060B2 (en) * 2007-08-20 2014-04-24 Oncotherapy Science, Inc. CDH3 peptide and medicinal agent comprising the same
CA2728285A1 (en) 2008-03-03 2009-09-11 Joule Unlimited, Inc. Engineered co2 fixing microorganisms producing carbon-based products of interest
US8048654B2 (en) * 2010-06-09 2011-11-01 Joule Unlimited Technologies, Inc. Methods and compositions for the recombinant biosynthesis of fatty acids and esters
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
BRPI0914440A8 (pt) 2008-10-17 2016-01-19 Joule Unlimited Inc Método para produção biogênica de etanol e cianobactéria geneticamente modificada
US20110020867A1 (en) * 2009-07-20 2011-01-27 Joule Unlimited, Inc. Constructs And Methods For Efficient Transformation Of Micro-Organisms For Production Of Carbon-Based Products Of Interest
NZ708078A (en) 2010-06-02 2017-01-27 Evolva Nutrition Inc Recombinant production of steviol glycosides
ES2372942B1 (es) * 2010-07-14 2012-12-04 Universidad De Cantabria Nueva enzima para la biosíntesis de isoprenoides.
CA3128532A1 (en) 2011-08-08 2013-02-14 Evolva Sa Recombinant production of steviol glycosides
US9557334B2 (en) 2012-10-25 2017-01-31 Run Them Sweet Llc Formulations and methods to provide nutrition to human and other patients
CA3171770A1 (en) 2013-02-06 2014-08-14 Evolva Sa Methods for improved production of rebaudioside d and rebaudioside m
US10017804B2 (en) 2013-02-11 2018-07-10 Evolva Sa Efficient production of steviol glycosides in recombinant hosts
BR112017002783A2 (pt) 2014-08-11 2017-12-19 Evolva Sa produção de glicosídeos de esteviol em hospedeiros recombinantes
MY191735A (en) 2014-09-09 2022-07-13 Evolva Sa Production of steviol glycosides in recombinant hosts
EP4148137A1 (de) 2015-01-30 2023-03-15 Evolva SA Herstellung von steviolglycosiden in rekombinanten wirten
CA2979931A1 (en) 2015-03-16 2016-09-22 Dsm Ip Assets B.V. Udp-glycosyltransferases
WO2017025362A1 (en) 2015-08-07 2017-02-16 Evolva Sa Production of steviol glycosides in recombinant hosts
US10982249B2 (en) 2016-04-13 2021-04-20 Evolva Sa Production of steviol glycosides in recombinant hosts
CN109312378A (zh) 2016-05-16 2019-02-05 埃沃尔瓦公司 在重组宿主中产生甜菊醇糖苷
CN110100006A (zh) 2016-11-07 2019-08-06 埃沃尔瓦公司 重组宿主中甜菊糖苷的生产
CN113337546B (zh) * 2021-06-04 2023-09-12 上海启讯医药科技有限公司 一种(s)-1,2,4-丁三醇的制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0154204B1 (de) 1984-03-06 1994-01-12 Mgi Pharma, Inc. Herbizide Resistenz in Pflanzen
GB9315751D0 (en) 1993-07-30 1993-09-15 Zeneca Ltd Dna,dna constructs,cells and plants derived therefrom
US5885782A (en) * 1994-09-13 1999-03-23 Nce Pharmaceuticals, Inc. Synthetic antibiotics
US6107071A (en) * 1996-09-24 2000-08-22 Smithkline Beecham Corporation Histidinol dehydrogenase
US5858367A (en) 1997-03-27 1999-01-12 Case Western Reserve University Methods for screening for antimicrobials utilizing AarC and compositions thereof
WO1999011757A1 (en) 1997-09-02 1999-03-11 Washington State University Research Foundation NUCLEIC AND AMINO ACID SEQUENCES FOR A NOVEL TRANSKETOLASE FROM $i (MENTHA PIPERITA)
DE19752700A1 (de) 1997-11-28 1999-06-02 Hoechst Schering Agrevo Gmbh 1-Desoxy-D-xylulose-5-phosphat Synthase, Verfahren zur Identifizierung von Effektoren der 1-Desoxy-D-xylulose-5-phosphat Synthase und Effektoren der 1-Desoxy-D-xylulose-5-phosphat Synthase
JP2002511486A (ja) 1998-04-14 2002-04-16 ヨマー、ハッサン 化学活性成分の同定法および1−デソキシ−d−キシルロース−5−リン酸の生合成経路を阻害する活性成分
EP1078045A1 (de) 1998-05-13 2001-02-28 University Of Maryland College Park Methoden zur modifikation der herstellung von isopenyl-pyrophosphat, dimethylallyl-pyrophosphat und/oder isoprenoide
OA11656A (en) 1998-09-22 2004-12-08 Jomaa Pharmaka Gmbh Genes of the 1-deoxy-D-xylulose biosynthetic pathway.
EP1141379A1 (de) 1998-12-14 2001-10-10 Adelbert Bacher Screening für inhibitoren von terpenoiden-biosynthese
TR200103326T2 (tr) 1999-05-21 2002-04-22 Jomaa Pharmaka Gmbh İsoprenoidin konsantrasyonunu değiştirmek için deoksi-D-ksiluloz fosfat biyosentetik yoluna ait genlerin kullanımı
DE10021688A1 (de) 2000-05-05 2001-11-15 Hassan Jomaa Gene des 1-Desoxy-D-xylulose-Biosynthesewegs
DE10027821A1 (de) 2000-06-05 2001-12-06 Adelbert Bacher Der Mevalonat-unabhängige Isoprenoidbiosyntheseweg
AU2001290522B2 (en) 2000-08-07 2006-11-30 Monsanto Technology Llc Methyl-D-erythritol phosphate pathway genes
DE10201458A1 (de) 2001-04-11 2002-10-17 Adelbert Bacher Intermediate und Enzyme des Mevalonat-unabhängigen Isoprenoidbiosyntheseweg
AU2002319171A1 (en) 2001-05-15 2002-11-25 Adelbert Bacher Crystal structure of 2c-methyl-d-erythritol 2,4-cyclodiphosphate synthase
AU2002322265A1 (en) 2001-06-18 2003-01-02 Structural Genomix Crystals and structure of 2c-methyl-d-erythritol 2,4-cyclodiphosphate synthase mecps

Also Published As

Publication number Publication date
EP1198575A1 (de) 2002-04-24
US7122331B1 (en) 2006-10-17
AU6280300A (en) 2001-03-05
EP1198575B1 (de) 2007-09-19
WO2001011055A1 (en) 2001-02-15
US7534742B2 (en) 2009-05-19
DE60036477D1 (en) 2007-10-31
US20070015216A1 (en) 2007-01-18
DE60036477T2 (de) 2008-06-12

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