EP1141379A1 - Screening für inhibitoren von terpenoiden-biosynthese - Google Patents

Screening für inhibitoren von terpenoiden-biosynthese

Info

Publication number
EP1141379A1
EP1141379A1 EP99963515A EP99963515A EP1141379A1 EP 1141379 A1 EP1141379 A1 EP 1141379A1 EP 99963515 A EP99963515 A EP 99963515A EP 99963515 A EP99963515 A EP 99963515A EP 1141379 A1 EP1141379 A1 EP 1141379A1
Authority
EP
European Patent Office
Prior art keywords
phosphate
deoxy
xylulose
methyl
labelled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99963515A
Other languages
English (en)
French (fr)
Inventor
Adelbert Bacher
Meinhart H. Zenk
Klaus Kis
Monika Fellermeier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1998157619 external-priority patent/DE19857619A1/de
Priority claimed from DE1999148615 external-priority patent/DE19948615A1/de
Priority claimed from DE1999148616 external-priority patent/DE19948616A1/de
Application filed by Individual filed Critical Individual
Publication of EP1141379A1 publication Critical patent/EP1141379A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5097—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving plant cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
EP99963515A 1998-12-14 1999-12-13 Screening für inhibitoren von terpenoiden-biosynthese Withdrawn EP1141379A1 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
DE1998157619 DE19857619A1 (de) 1998-12-14 1998-12-14 Verfahren zur Ermittlung von Inhibitoren der Terpenoid-Biosynthese
DE19857619 1998-12-14
DE19948616 1999-10-08
DE1999148615 DE19948615A1 (de) 1999-10-08 1999-10-08 Hochempfindliches Testverfahren auf Inhibitoren der Terpenbiosynthese
DE19948615 1999-10-08
DE1999148616 DE19948616A1 (de) 1999-10-08 1999-10-08 Ein schnelles Testverfahren auf Inhibitoren der Terpenoid-Biosynthese
PCT/EP1999/009870 WO2000036138A1 (en) 1998-12-14 1999-12-13 Screening for inhibitors of terpenoids biosynthesis

Publications (1)

Publication Number Publication Date
EP1141379A1 true EP1141379A1 (de) 2001-10-10

Family

ID=27218866

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99963515A Withdrawn EP1141379A1 (de) 1998-12-14 1999-12-13 Screening für inhibitoren von terpenoiden-biosynthese

Country Status (4)

Country Link
EP (1) EP1141379A1 (de)
JP (1) JP2002532101A (de)
AU (1) AU1978200A (de)
WO (1) WO2000036138A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60036477T2 (de) 1999-08-04 2008-06-12 Bacher, Adelbert, Prof. Dr.med. Dr.rer.nat. Isoprenoid biosynthese
DE10027821A1 (de) * 2000-06-05 2001-12-06 Adelbert Bacher Der Mevalonat-unabhängige Isoprenoidbiosyntheseweg
DE10201458A1 (de) 2001-04-11 2002-10-17 Adelbert Bacher Intermediate und Enzyme des Mevalonat-unabhängigen Isoprenoidbiosyntheseweg

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4846872A (en) * 1986-08-11 1989-07-11 Fujisawa Pharmaceutical Co., Ltd. Herbicide
DE19752700A1 (de) * 1997-11-28 1999-06-02 Hoechst Schering Agrevo Gmbh 1-Desoxy-D-xylulose-5-phosphat Synthase, Verfahren zur Identifizierung von Effektoren der 1-Desoxy-D-xylulose-5-phosphat Synthase und Effektoren der 1-Desoxy-D-xylulose-5-phosphat Synthase
CA2328157A1 (en) * 1998-04-14 1999-10-21 Jomaa Hassan Method for identifying chemical active agents and active agents for inhibiting the 1-desoxy-d-xylulose-5-phosphate biosynthetic pathway

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO0036138A1 *

Also Published As

Publication number Publication date
WO2000036138A1 (en) 2000-06-22
AU1978200A (en) 2000-07-03
JP2002532101A (ja) 2002-10-02

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