DE69229267T2 - Verfahren und zubereitungen zur isolierung von taxanen - Google Patents

Verfahren und zubereitungen zur isolierung von taxanen

Info

Publication number
DE69229267T2
DE69229267T2 DE69229267T DE69229267T DE69229267T2 DE 69229267 T2 DE69229267 T2 DE 69229267T2 DE 69229267 T DE69229267 T DE 69229267T DE 69229267 T DE69229267 T DE 69229267T DE 69229267 T2 DE69229267 T2 DE 69229267T2
Authority
DE
Germany
Prior art keywords
taxanes
disclosed
methods
preparations
insulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69229267T
Other languages
English (en)
Other versions
DE69229267D1 (de
Inventor
Hala Elsohly
Edward Croom
Mahmoud Elsohly
James Mcchesney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Mississippi
Original Assignee
University of Mississippi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Mississippi filed Critical University of Mississippi
Publication of DE69229267D1 publication Critical patent/DE69229267D1/de
Application granted granted Critical
Publication of DE69229267T2 publication Critical patent/DE69229267T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
DE69229267T 1991-04-19 1992-04-14 Verfahren und zubereitungen zur isolierung von taxanen Expired - Fee Related DE69229267T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69080591A 1991-04-19 1991-04-19
PCT/US1992/003088 WO1992018492A1 (en) 1991-04-19 1992-04-14 Methods and compositions for isolating taxanes

Publications (2)

Publication Number Publication Date
DE69229267D1 DE69229267D1 (de) 1999-07-01
DE69229267T2 true DE69229267T2 (de) 1999-12-16

Family

ID=24774037

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69229267T Expired - Fee Related DE69229267T2 (de) 1991-04-19 1992-04-14 Verfahren und zubereitungen zur isolierung von taxanen

Country Status (15)

Country Link
US (2) US5480639A (de)
EP (1) EP0580759B1 (de)
JP (1) JP3222466B2 (de)
CN (1) CN1069965A (de)
AT (1) ATE180477T1 (de)
AU (1) AU1888792A (de)
DE (1) DE69229267T2 (de)
IE (1) IE921251A1 (de)
IL (1) IL101594A0 (de)
MX (1) MX9201775A (de)
PT (1) PT100401A (de)
SI (1) SI9200054B (de)
WO (1) WO1992018492A1 (de)
YU (1) YU40892A (de)
ZA (1) ZA922769B (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7264951B1 (en) 1992-02-20 2007-09-04 Phyton, Inc. Enhanced production of taxol and taxanes by cell cultures of Taxus species
FR2696463B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé d'obtention de la désacétyl-10 baccatine III.
KR100371062B1 (ko) * 1992-11-27 2003-04-21 에프.에이치.포울딩 앤드 컴퍼니 리미티드 안정성이향상된주사가능한택솔조성물및이를제형화하는방법
WO1994013827A1 (en) * 1992-12-07 1994-06-23 Michigan State University PROCESS FOR THE ISOLATION AND PURIFICATION OF TAXOL AND TAXANES FROM TAXUS spp
FR2714053B1 (fr) * 1993-12-22 1996-03-08 Pf Medicament Procédé d'extraction et d'isolement de la 10-désacétylbaccatine III.
CN1112433A (zh) * 1994-05-24 1995-11-29 郭明 红豆杉属植物提取物及其应用
US5900367A (en) * 1995-04-29 1999-05-04 Samyang Genex Co., Ltd. Method for purifying taxol from taxus biomass
US5654448A (en) * 1995-10-02 1997-08-05 Xechem International, Inc. Isolation and purification of paclitaxel from organic matter containing paclitaxel, cephalomannine and other related taxanes
CN1054382C (zh) * 1996-03-05 2000-07-12 核工业北京化工冶金研究院 用反相制备液相色谱法分离纯化紫杉醇的方法
EP1538214A1 (de) 1996-05-24 2005-06-08 Phyton, Inc. Erhöhte Produktion von Taxanen durch Zellkulturen von Taxus-Arten
US5965752A (en) * 1996-08-23 1999-10-12 Institut National De La Recherche Scientifique Preparative scale isolation and purification of taxanes
WO1999036413A1 (en) * 1998-01-14 1999-07-22 Bristol-Myers Squibb Company Novel crystalline complexes of baccatin iii with imidazole, 2-methylimidazole or isopropanol
DE19822881B4 (de) * 1998-05-22 2004-03-11 Institut für Bioanalytik Umwelt-Toxikologie & Biotechnologie Halle GmbH Verfahren zur Herstellung von Baccatin-III durch enzymatische Synthese
US6136989A (en) * 1998-12-30 2000-10-24 Phytogen Life Sciences, Incorporated Method for high yield and large scale extraction of paclitaxel from paclitaxel-containing material
US5969165A (en) * 1999-01-07 1999-10-19 508037 (Nb) Inc. Isolation and purification of paclitaxel and other related taxanes by industrial preparative low pressure chromatography on a polymeric resin column
EP2289549A3 (de) 1999-10-01 2011-06-15 Immunogen, Inc. Immunokonjugate für Krebsbehandlung
EP1254128A2 (de) 2000-01-13 2002-11-06 Purdue Research Foundation Herstellung von taxol und taxanen
US6452024B1 (en) 2000-02-22 2002-09-17 Chaichem Pharmaceuticals International Process for extraction and purification of paclitaxel from natural sources
KR100666652B1 (ko) * 2000-02-25 2007-01-09 한화석유화학 주식회사 식물 원료로부터 초임계 유체를 이용하여 탁솔을 제조하는방법
KR100833805B1 (ko) * 2000-04-19 2008-05-30 니치유 가부시키가이샤 화장품 조성물
US20020155177A1 (en) * 2000-09-29 2002-10-24 Krasutsky Pavel A. Process for extracting compounds from plants
WO2002026343A2 (en) * 2000-09-29 2002-04-04 Regents Of The University Of Minnesota Process for extracting compounds from plants
WO2002038556A2 (en) 2000-11-08 2002-05-16 Actipharm, Inc. Process for mass production of gmp paclitaxel and related taxanes
US6333419B1 (en) 2000-11-28 2001-12-25 Indena Spa Chromatographic separation method of paclitaxel and cephalomannin
WO2004054959A1 (en) * 2002-12-16 2004-07-01 Council Of Scientific And Industrial Research Process for isolating brevifoliol
US7579491B2 (en) 2002-12-30 2009-08-25 Council Of Scientific And Industrial Research Process for preparing brevifoliol
US6759539B1 (en) 2003-02-27 2004-07-06 Chaichem Pharmaceuticals International Process for isolation and purification of paclitaxel from natural sources
US20070129171A1 (en) * 2005-10-12 2007-06-07 Simonds Vincent J Method for Manufacturing a Golf Product
JP4651717B2 (ja) * 2006-03-24 2011-03-16 ポステック ファウンデーション ククルビツリルを結合されたシリカゲルを用いた静止相およびカラム、そして該カラムを用いたタキソールの分離方法
US9127208B2 (en) 2006-04-03 2015-09-08 Pharmatherm Chemicals, Inc. Thermal extraction method and product
US7905990B2 (en) 2007-11-20 2011-03-15 Ensyn Renewables, Inc. Rapid thermal conversion of biomass
US20110284359A1 (en) 2010-05-20 2011-11-24 Uop Llc Processes for controlling afterburn in a reheater and for controlling loss of entrained solid particles in combustion product flue gas
US8499702B2 (en) 2010-07-15 2013-08-06 Ensyn Renewables, Inc. Char-handling processes in a pyrolysis system
US9441887B2 (en) 2011-02-22 2016-09-13 Ensyn Renewables, Inc. Heat removal and recovery in biomass pyrolysis
CN102219764B (zh) * 2011-05-12 2013-06-26 河南省科学院化学研究所有限公司 一种工业化分离纯化紫杉醇的方法
US9347005B2 (en) 2011-09-13 2016-05-24 Ensyn Renewables, Inc. Methods and apparatuses for rapid thermal processing of carbonaceous material
US10400175B2 (en) 2011-09-22 2019-09-03 Ensyn Renewables, Inc. Apparatuses and methods for controlling heat for rapid thermal processing of carbonaceous material
US9044727B2 (en) 2011-09-22 2015-06-02 Ensyn Renewables, Inc. Apparatuses and methods for controlling heat for rapid thermal processing of carbonaceous material
US10041667B2 (en) 2011-09-22 2018-08-07 Ensyn Renewables, Inc. Apparatuses for controlling heat for rapid thermal processing of carbonaceous material and methods for the same
US9109177B2 (en) 2011-12-12 2015-08-18 Ensyn Renewables, Inc. Systems and methods for renewable fuel
US9670413B2 (en) 2012-06-28 2017-06-06 Ensyn Renewables, Inc. Methods and apparatuses for thermally converting biomass
TWI645026B (zh) 2013-06-26 2018-12-21 安信再生公司 可再生燃料之系統及方法
CA2995845A1 (en) 2015-08-21 2017-03-02 Ensyn Renewables, Inc. Liquid biomass heating system
CA3048681A1 (en) 2016-12-29 2018-07-05 Ensyn Renewables, Inc. Demetallization of liquid biomass

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4206221A (en) * 1979-01-03 1980-06-03 The United States Of America As Represented By The Secretary Of Agriculture Cephalomannine and its use in treating leukemic tumors
FR2601676B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Procede de preparation du taxol et du desacetyl-10 taxol
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
US5019504A (en) * 1989-03-23 1991-05-28 The United States Of America As Represented By The Secretary Of Agriculture Production of taxol or taxol-like compounds in cell culture

Also Published As

Publication number Publication date
JP3222466B2 (ja) 2001-10-29
ATE180477T1 (de) 1999-06-15
ZA922769B (en) 1992-12-30
YU40892A (sh) 1994-06-24
PT100401A (pt) 1993-08-31
WO1992018492A1 (en) 1992-10-29
US5618538A (en) 1997-04-08
SI9200054B (en) 2001-12-31
EP0580759B1 (de) 1999-05-26
AU1888792A (en) 1992-11-17
DE69229267D1 (de) 1999-07-01
US5480639A (en) 1996-01-02
SI9200054A (en) 1992-11-27
MX9201775A (es) 1992-10-01
IE921251A1 (en) 1992-10-21
JPH06509560A (ja) 1994-10-27
IL101594A0 (en) 1992-12-30
EP0580759A1 (de) 1994-02-02
CN1069965A (zh) 1993-03-17

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee