BR9709361B1 - produção aumentada de taxanos por culturas de células de espécie taxus. - Google Patents
produção aumentada de taxanos por culturas de células de espécie taxus.Info
- Publication number
- BR9709361B1 BR9709361B1 BRPI9709361-0A BR9709361A BR9709361B1 BR 9709361 B1 BR9709361 B1 BR 9709361B1 BR 9709361 A BR9709361 A BR 9709361A BR 9709361 B1 BR9709361 B1 BR 9709361B1
- Authority
- BR
- Brazil
- Prior art keywords
- cell cultures
- taxus species
- species cell
- taxane production
- taxus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0025—Culture media for plant cell or plant tissue culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/04—Plant cells or tissues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P15/00—Preparation of compounds containing at least three condensed carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65303696A | 1996-05-24 | 1996-05-24 | |
PCT/US1997/008907 WO1997044476A1 (en) | 1996-05-24 | 1997-05-27 | Enhanced production of taxanes by cell cultures of taxus species |
Publications (2)
Publication Number | Publication Date |
---|---|
BR9709361A BR9709361A (pt) | 1999-08-10 |
BR9709361B1 true BR9709361B1 (pt) | 2009-05-05 |
Family
ID=24619244
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI9709361-0A BR9709361B1 (pt) | 1996-05-24 | 1997-05-27 | produção aumentada de taxanos por culturas de células de espécie taxus. |
Country Status (16)
Country | Link |
---|---|
US (2) | US8338143B2 (pt) |
EP (3) | EP0954596B1 (pt) |
JP (5) | JP4047929B2 (pt) |
KR (7) | KR20100070388A (pt) |
AT (1) | ATE315097T1 (pt) |
AU (1) | AU727425B2 (pt) |
BR (1) | BR9709361B1 (pt) |
CA (2) | CA2638292A1 (pt) |
DE (1) | DE69735059T2 (pt) |
DK (1) | DK0954596T3 (pt) |
ES (1) | ES2256887T3 (pt) |
HU (2) | HUP9901788A3 (pt) |
IL (1) | IL127062A (pt) |
PT (1) | PT954596E (pt) |
TR (1) | TR199802426T2 (pt) |
WO (1) | WO1997044476A1 (pt) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20100070388A (ko) * | 1996-05-24 | 2010-06-25 | 디에프비 바이오테크 인코포레이티드 | 탁수스종의 세포 배양에 의한 탁산의 생산 증진 방법 |
KR100287465B1 (ko) * | 1997-06-25 | 2001-05-02 | 나까니시 히로유끼 | 탁산형 디테르펜의 제조방법 |
TW200304947A (en) * | 2002-02-08 | 2003-10-16 | Bristol Myers Squibb Co | Compositions and methods for latering biosynthesis of taxanes and taxane-related compounds |
WO2006129988A1 (en) * | 2005-06-03 | 2006-12-07 | Samyang Genex Corporation | Mass production of secondary metabolite in plant cell culture by treatment of saccharide mixture in medicum |
US8053238B2 (en) | 2005-10-31 | 2011-11-08 | Unhwa Corporation | Isolated population of plant single cells and method of preparing the same |
US8017397B2 (en) * | 2005-10-31 | 2011-09-13 | Unhwa Corporation | Isolated population of plant single cells and method of preparing same |
KR101064518B1 (ko) | 2007-09-21 | 2011-09-19 | 주식회사 운화 | 저장근을 가지는 초본식물의 형성층 유래 식물줄기세포주 및 이의 분리방법 |
KR101100867B1 (ko) * | 2008-05-14 | 2012-01-02 | 주식회사 운화 | 주목의 형성층 또는 전형성층 유래 식물줄기세포주를 유효성분으로 함유하는 항산화, 항염증 또는 항노화용 조성물 |
WO2010148338A1 (en) | 2009-06-18 | 2010-12-23 | Phyton Holdings, Llc | Production of alkaloids by liliaceae cell culture |
FR2952072B1 (fr) | 2009-11-05 | 2013-09-27 | Pf Medicament | Procede de production de triptolide |
WO2013164834A1 (en) * | 2012-05-04 | 2013-11-07 | Phyto Biotech Pvt. Ltd. | Cost-effective process for commercial production of paclitaxel |
CN103570647A (zh) * | 2013-11-06 | 2014-02-12 | 湖南农业大学 | 从红豆杉细胞培养液中制备高纯度紫杉醇的方法 |
DK3077523T3 (da) | 2013-12-02 | 2020-07-20 | Phyton Holdings Llc | Produktion af thapsigarginer ved hjælp af Thapsia cellesuspensionskultur |
US10058542B1 (en) | 2014-09-12 | 2018-08-28 | Thioredoxin Systems Ab | Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith |
WO2016150860A1 (en) | 2015-03-20 | 2016-09-29 | Phyton Biotech Gmbh | Production of ingenol, ingenol esters and/or tiglian-3-one derivatives by euphorbiaceae plant cell suspension cultures |
CN105349592B (zh) * | 2015-12-09 | 2018-11-27 | 天津艾赛博生物技术有限公司 | 代谢互补的植物细胞系混种培养生产次级代谢产物的方法 |
CN106636242A (zh) * | 2016-12-20 | 2017-05-10 | 天津艾赛博生物技术有限公司 | 一种红豆杉细胞长期培养生产紫杉烷的调控方法 |
JP7359527B2 (ja) * | 2017-05-31 | 2023-10-11 | トヨタ自動車株式会社 | 電池搭載構造 |
WO2022026613A2 (en) * | 2020-07-28 | 2022-02-03 | Impello Biosciences, Inc. | Methods and compositions for altering secondary metabolites in plants |
CN113416689B (zh) * | 2021-08-04 | 2023-01-10 | 海南鑫开源医药科技有限公司 | 一种利用植物细胞发酵技术生产高丽槐素的方法 |
CN115948494B (zh) * | 2022-09-12 | 2024-07-16 | 昆明理工大学 | 一种利用三七细胞合成齐墩果烷型皂苷的方法 |
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DE3270112D1 (en) | 1981-08-11 | 1986-04-30 | Mitsui Petrochemical Ind | Method for producing secondary metabolites of plants |
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EP0378921A3 (en) | 1988-12-21 | 1990-09-19 | Idaho Research Foundation, Inc. | Enhancement of plant metabolite production by timed elicitation |
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US5334529A (en) | 1989-06-27 | 1994-08-02 | Escagenetics Corporation | Stably transformed coffee plant cells and plantlets |
US5015744A (en) | 1989-11-14 | 1991-05-14 | Florida State University | Method for preparation of taxol using an oxazinone |
CA2083595C (en) | 1990-05-25 | 2003-03-25 | Clarence A. Ryan, Jr. | Method of inducing plant defense mechanisms |
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JPH05244971A (ja) | 1992-03-06 | 1993-09-24 | Nippon Oil Co Ltd | タキサン類化合物の製造方法 |
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CA2434692A1 (en) | 1992-04-07 | 1993-10-08 | Paul M. Cino | Callus cell induction and the preparation of taxanes |
US5322779A (en) | 1992-04-16 | 1994-06-21 | The Research And Development Institute, Inc. At Montana State University | Taxol production by taxomyces andreanae |
CA2136213A1 (en) | 1992-05-21 | 1993-11-25 | Richard N. Arteca | Cultured taxu tissues as a source of taxol, related taxanes and other novel anti-tumor/anti-viral compounds |
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JPH0870880A (ja) | 1994-09-05 | 1996-03-19 | Osaka Organic Chem Ind Ltd | タキソールの培養生産法 |
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JP3746550B2 (ja) | 1994-12-05 | 2006-02-15 | 三井化学株式会社 | タキサン型ジテルペンの製造方法 |
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JPH1052295A (ja) | 1996-08-09 | 1998-02-24 | Nippon Oil Co Ltd | タキサン類化合物の製造方法(ii) |
JPH1052296A (ja) | 1996-08-09 | 1998-02-24 | Nippon Oil Co Ltd | タキサン類化合物の製造方法(iii) |
ATE258594T1 (de) | 1997-02-19 | 2004-02-15 | Phytobiotech Inc | Verfahren zur steigerung des wachstums von pflanzenzellkulturen |
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-
1997
- 1997-05-27 KR KR1020107012489A patent/KR20100070388A/ko not_active Application Discontinuation
- 1997-05-27 HU HU9901788A patent/HUP9901788A3/hu unknown
- 1997-05-27 BR BRPI9709361-0A patent/BR9709361B1/pt not_active IP Right Cessation
- 1997-05-27 DE DE69735059T patent/DE69735059T2/de not_active Expired - Lifetime
- 1997-05-27 WO PCT/US1997/008907 patent/WO1997044476A1/en active IP Right Grant
- 1997-05-27 HU HU0302357A patent/HU223267B1/hu not_active IP Right Cessation
- 1997-05-27 IL IL12706297A patent/IL127062A/xx not_active IP Right Cessation
- 1997-05-27 JP JP54282497A patent/JP4047929B2/ja not_active Expired - Fee Related
- 1997-05-27 ES ES97926731T patent/ES2256887T3/es not_active Expired - Lifetime
- 1997-05-27 EP EP97926731A patent/EP0954596B1/en not_active Expired - Lifetime
- 1997-05-27 CA CA002638292A patent/CA2638292A1/en not_active Abandoned
- 1997-05-27 AT AT97926731T patent/ATE315097T1/de not_active IP Right Cessation
- 1997-05-27 AU AU31430/97A patent/AU727425B2/en not_active Ceased
- 1997-05-27 KR KR1020107012491A patent/KR20100070389A/ko not_active Application Discontinuation
- 1997-05-27 EP EP20030026211 patent/EP1398384A1/en not_active Ceased
- 1997-05-27 KR KR10-1998-0709509A patent/KR100897457B1/ko not_active IP Right Cessation
- 1997-05-27 KR KR1020127032650A patent/KR20120138251A/ko not_active Application Discontinuation
- 1997-05-27 PT PT97926731T patent/PT954596E/pt unknown
- 1997-05-27 KR KR1020147011093A patent/KR20140062179A/ko not_active Application Discontinuation
- 1997-05-27 KR KR1020077020228A patent/KR20070094867A/ko not_active Application Discontinuation
- 1997-05-27 TR TR1998/02426T patent/TR199802426T2/xx unknown
- 1997-05-27 EP EP05002665A patent/EP1538214A1/en not_active Ceased
- 1997-05-27 DK DK97926731T patent/DK0954596T3/da active
- 1997-05-27 CA CA002256357A patent/CA2256357C/en not_active Expired - Lifetime
- 1997-05-27 KR KR1020087030132A patent/KR20090005241A/ko not_active Application Discontinuation
-
2007
- 2007-02-07 JP JP2007028425A patent/JP2007143557A/ja not_active Withdrawn
-
2008
- 2008-02-25 JP JP2008043232A patent/JP2008167764A/ja not_active Withdrawn
-
2010
- 2010-12-17 US US12/972,064 patent/US8338143B2/en not_active Expired - Fee Related
-
2011
- 2011-08-03 JP JP2011170533A patent/JP2011212029A/ja active Pending
-
2012
- 2012-09-14 US US13/618,284 patent/US20130017582A1/en not_active Abandoned
- 2012-12-06 JP JP2012267338A patent/JP2013046643A/ja active Pending
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