DK0672162T3 - Forøget produktion af taxol og taxaner ved hjælp af cellekulturer af Taxus-arter - Google Patents

Forøget produktion af taxol og taxaner ved hjælp af cellekulturer af Taxus-arter

Info

Publication number
DK0672162T3
DK0672162T3 DK93906156T DK93906156T DK0672162T3 DK 0672162 T3 DK0672162 T3 DK 0672162T3 DK 93906156 T DK93906156 T DK 93906156T DK 93906156 T DK93906156 T DK 93906156T DK 0672162 T3 DK0672162 T3 DK 0672162T3
Authority
DK
Denmark
Prior art keywords
taxanes
taxol
taxus species
cell cultures
increased production
Prior art date
Application number
DK93906156T
Other languages
English (en)
Inventor
Venkataraman Bringi
Prakash G Kadkade
Original Assignee
Phyton Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27126086&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0672162(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Phyton Inc filed Critical Phyton Inc
Application granted granted Critical
Publication of DK0672162T3 publication Critical patent/DK0672162T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0025—Culture media for plant cell or plant tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04—Plant cells or tissues

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK93906156T 1992-02-20 1993-02-22 Forøget produktion af taxol og taxaner ved hjælp af cellekulturer af Taxus-arter DK0672162T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83914492A 1992-02-20 1992-02-20
US07/874,344 US5407816A (en) 1992-02-20 1992-04-24 Enhanced production of taxol and taxanes by cell cultures of taxus species
PCT/US1993/001576 WO1993017121A1 (en) 1992-02-20 1993-02-22 Enhanced production of taxol and taxanes by cell cultures of taxus species

Publications (1)

Publication Number Publication Date
DK0672162T3 true DK0672162T3 (da) 2000-12-18

Family

ID=27126086

Family Applications (2)

Application Number Title Priority Date Filing Date
DK99202507T DK0960944T3 (da) 1992-02-20 1993-02-22 Forbedret produktion af taxol og taxaner fra cellekulturer af taxus-arter
DK93906156T DK0672162T3 (da) 1992-02-20 1993-02-22 Forøget produktion af taxol og taxaner ved hjælp af cellekulturer af Taxus-arter

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK99202507T DK0960944T3 (da) 1992-02-20 1993-02-22 Forbedret produktion af taxol og taxaner fra cellekulturer af taxus-arter

Country Status (16)

Country Link
US (1) US5407816A (da)
EP (3) EP0960944B1 (da)
JP (5) JP3513151B2 (da)
KR (6) KR20090116792A (da)
AT (3) ATE256197T1 (da)
AU (1) AU672194B2 (da)
CA (1) CA2130745C (da)
DE (3) DE69334352D1 (da)
DK (2) DK0960944T3 (da)
ES (3) ES2361150T3 (da)
GR (1) GR3034722T3 (da)
HK (2) HK1003718A1 (da)
NZ (1) NZ249734A (da)
PT (2) PT960944E (da)
SG (1) SG46427A1 (da)
WO (1) WO1993017121A1 (da)

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US5850032A (en) * 1992-04-01 1998-12-15 Union Camp Corporation Method for production of plant biological products in precocious neomorphic embryoids
CA2434692A1 (en) * 1992-04-07 1993-10-08 Paul M. Cino Callus cell induction and the preparation of taxanes
CA2136213A1 (en) * 1992-05-21 1993-11-25 Richard N. Arteca Cultured taxu tissues as a source of taxol, related taxanes and other novel anti-tumor/anti-viral compounds
JP2967532B2 (ja) * 1992-06-11 1999-10-25 日石三菱株式会社 タキサン類化合物の製造方法
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
KR950005081B1 (ko) * 1993-07-06 1995-05-18 산림청임목육종연구소 주목 종자의 씨눈 유래의 체세포배 및 체세포배성세포 혹은 그 배양배지로부터 택솔(Taxol) 및 그 유도체를 생산하는 방법
WO1995014103A1 (fr) * 1993-11-15 1995-05-26 Mitsui Petrochemical Industries, Ltd. Procede de production de diterpene de taxane et procede de recolte de cellules de culture capables de produire du diterpene de taxane a haut rendement
IL113447A (en) * 1994-04-22 1999-01-26 Us Agriculture Attractant for controlling insects and apparatus containing the same
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JP2001521503A (ja) 1997-03-31 2001-11-06 ネオルックス コーポレイション 血管平滑筋細胞の治療的阻害物質
US5801193A (en) * 1997-04-15 1998-09-01 Immune Modulation, Inc. Compositions and methods for immunosuppressing
KR100287465B1 (ko) 1997-06-25 2001-05-02 나까니시 히로유끼 탁산형 디테르펜의 제조방법
KR100266448B1 (ko) * 1997-06-26 2000-09-15 박종헌 식물세포 배양 중의 온도변화에 의한 택솔의 대량생산 방법
EP1068192B1 (en) 1998-01-14 2002-06-12 Bristol-Myers Squibb Company Novel crystalline complexes of baccatin iii with imidazole, 2-methylimidazole or isopropanol
US6093422A (en) 1998-01-23 2000-07-25 Zodiac Pool Care, Inc. Biocidal compositions for treating water
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DE60131537T2 (de) 2000-06-22 2008-10-23 Nitromed, Inc., Lexington Nitrosierte und nitrosylierte taxane, zubereitungen und methoden der verwendung
WO2002040633A2 (en) * 2000-11-14 2002-05-23 Regents Of The University Of California Optimized antitrypsin expression in rice cell culture
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CN101421392A (zh) * 2004-02-13 2009-04-29 菲托生物技术公司 茚满酰酰胺在刺激紫杉属次生代谢中的应用
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KR101064518B1 (ko) * 2007-09-21 2011-09-19 주식회사 운화 저장근을 가지는 초본식물의 형성층 유래 식물줄기세포주 및 이의 분리방법
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WO2010137877A2 (ko) * 2009-05-26 2010-12-02 주식회사 운화 국화과의 형성층 유래 식물줄기세포 및 이의 분리배양방법
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CN101671319B (zh) * 2009-09-18 2012-02-29 应成杰 红豆杉无毒提取物的提取工艺
CN103237457A (zh) 2010-10-04 2013-08-07 戴安娜植物科学有限公司 从植物细胞培养物产生和提取原花青素
JP2012217441A (ja) * 2011-04-14 2012-11-12 Housetec Inc タキサン類の生産方法、およびカルス誘導方法
CN102715086B (zh) * 2012-06-19 2014-04-16 湖南农业大学 一种红豆杉试管苗诱导获得愈伤组织和悬浮细胞的方法
CN102715085B (zh) * 2012-06-19 2014-04-16 湖南农业大学 一种诱导红豆杉种子种胚获得愈伤组织和悬浮细胞的方法
CN103058961B (zh) * 2013-01-28 2015-04-29 普洱市红宝生物科技有限公司 从云南红豆杉中提取紫杉醇的方法
CN103570647A (zh) * 2013-11-06 2014-02-12 湖南农业大学 从红豆杉细胞培养液中制备高纯度紫杉醇的方法
KR101603539B1 (ko) * 2014-08-11 2016-03-15 영남대학교 산학협력단 택솔을 생산하는 콜레토트리쿰 데마티움 균주 및 그 용도
KR101786448B1 (ko) 2015-08-24 2017-10-18 영남대학교 산학협력단 택솔을 생산하는 트라이코더마 비리데슨스 tx1 균주 및 이의 용도
CN109022510A (zh) * 2018-08-23 2018-12-18 吉首大学 一种利用南方红豆杉菌根菌与活组织细胞共培养生产紫杉醇及10-dabⅲ的方法
CN110441439B (zh) * 2019-07-01 2022-03-01 杭州师范大学 区分密叶红豆杉和云南红豆杉的代谢标志物及其检测方法
WO2022162101A1 (en) * 2021-01-28 2022-08-04 Phyto-Technics Bv Production of taxol from taxus cuttings

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019504A (en) * 1989-03-23 1991-05-28 The United States Of America As Represented By The Secretary Of Agriculture Production of taxol or taxol-like compounds in cell culture
JPH03216123A (ja) * 1990-01-17 1991-09-24 Nitsusen Kagaku Kogyo Kk 培養植物体の増殖促進方法
JPH05507629A (ja) * 1991-02-12 1993-11-04 新日本製鐵株式会社 イチイの組織培養によるタキソールの生産方法
US5407816A (en) * 1992-02-20 1995-04-18 Phyton Catalytic, Inc. Enhanced production of taxol and taxanes by cell cultures of taxus species

Also Published As

Publication number Publication date
EP1378574B1 (en) 2011-04-06
KR100285788B1 (ko) 2001-05-02
SG46427A1 (en) 1998-02-20
HK1024936A1 (en) 2000-10-27
KR950700996A (ko) 1995-02-20
HK1003718A1 (en) 1998-11-06
KR100392036B1 (ko) 2003-07-16
WO1993017121A1 (en) 1993-09-02
ATE504659T1 (de) 2011-04-15
KR20040000390A (ko) 2004-01-03
PT960944E (pt) 2004-04-30
ES2361150T3 (es) 2011-06-14
EP0960944B1 (en) 2003-12-10
EP0672162A4 (en) 1995-11-29
DE69329154D1 (de) 2000-09-07
KR20070104684A (ko) 2007-10-26
DK0960944T3 (da) 2004-04-05
JP3513151B2 (ja) 2004-03-31
NZ249734A (en) 1996-08-27
JP2004000285A (ja) 2004-01-08
KR20090116792A (ko) 2009-11-11
GR3034722T3 (en) 2001-01-31
DE69333358T2 (de) 2004-08-19
CA2130745C (en) 2008-01-22
EP0960944A1 (en) 1999-12-01
AU672194B2 (en) 1996-09-26
CA2130745A1 (en) 1993-09-02
JP2008131955A (ja) 2008-06-12
KR20110079863A (ko) 2011-07-08
DE69329154T2 (de) 2001-06-07
EP0672162A1 (en) 1995-09-20
EP1378574A1 (en) 2004-01-07
ES2213328T3 (es) 2004-08-16
ATE256197T1 (de) 2003-12-15
AU3729193A (en) 1993-09-13
JP2009183305A (ja) 2009-08-20
EP0672162B1 (en) 2000-08-02
US5407816A (en) 1995-04-18
ES2150938T3 (es) 2000-12-16
PT672162E (pt) 2001-01-31
JPH07506721A (ja) 1995-07-27
JP2005348751A (ja) 2005-12-22
DE69333358D1 (de) 2004-01-22
ATE195146T1 (de) 2000-08-15
DE69334352D1 (de) 2011-05-19

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