ATE146527T1 - Verfahren zur herstellung von taxol mittels taxusspezies-zellkultur - Google Patents

Verfahren zur herstellung von taxol mittels taxusspezies-zellkultur

Info

Publication number
ATE146527T1
ATE146527T1 AT92904407T AT92904407T ATE146527T1 AT E146527 T1 ATE146527 T1 AT E146527T1 AT 92904407 T AT92904407 T AT 92904407T AT 92904407 T AT92904407 T AT 92904407T AT E146527 T1 ATE146527 T1 AT E146527T1
Authority
AT
Austria
Prior art keywords
taxol
callus
cell culture
cells containing
suspension culture
Prior art date
Application number
AT92904407T
Other languages
English (en)
Inventor
Koji Saito
Hiroaki Ohashi
Masaaki Hibi
Makoto Tahara
Original Assignee
Nippon Steel Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Steel Corp filed Critical Nippon Steel Corp
Application granted granted Critical
Publication of ATE146527T1 publication Critical patent/ATE146527T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04Plant cells or tissues
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT92904407T 1991-02-12 1992-02-10 Verfahren zur herstellung von taxol mittels taxusspezies-zellkultur ATE146527T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1901091 1991-02-12

Publications (1)

Publication Number Publication Date
ATE146527T1 true ATE146527T1 (de) 1997-01-15

Family

ID=11987535

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92904407T ATE146527T1 (de) 1991-02-12 1992-02-10 Verfahren zur herstellung von taxol mittels taxusspezies-zellkultur

Country Status (6)

Country Link
EP (1) EP0529083B1 (de)
JP (1) JPH05507629A (de)
AT (1) ATE146527T1 (de)
CA (1) CA2080000A1 (de)
DE (1) DE69216003D1 (de)
WO (1) WO1992013961A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7264951B1 (en) 1992-02-20 2007-09-04 Phyton, Inc. Enhanced production of taxol and taxanes by cell cultures of Taxus species
US5407816A (en) * 1992-02-20 1995-04-18 Phyton Catalytic, Inc. Enhanced production of taxol and taxanes by cell cultures of taxus species
CA2092849C (en) * 1992-04-07 2003-11-18 Paul M. Cino Callus cell induction and the preparation of taxanes
CA2136213A1 (en) * 1992-05-21 1993-11-25 Richard N. Arteca Cultured taxu tissues as a source of taxol, related taxanes and other novel anti-tumor/anti-viral compounds
US5279949A (en) * 1992-12-07 1994-01-18 Board Of Trustees Operating Michigan State University Process for the isolation and purification of taxol and taxanes from Taxus spp
KR950005081B1 (ko) * 1993-07-06 1995-05-18 산림청임목육종연구소 주목 종자의 씨눈 유래의 체세포배 및 체세포배성세포 혹은 그 배양배지로부터 택솔(Taxol) 및 그 유도체를 생산하는 방법
US5547866A (en) * 1994-07-20 1996-08-20 The Regents Of The University Of California Taxane production in haploid-derived cell cultures
KR960037826A (ko) * 1995-04-27 1996-11-19 김경환 택서스속 식물세포의 반연속식 배양방법
JP4047929B2 (ja) 1996-05-24 2008-02-13 ファイトン・インコーポレーテッド タキサス種の細胞培養によるタキサンの増強生産
CN102687667B (zh) * 2012-06-19 2013-09-04 湖南农业大学 一种红豆杉成熟胚乳诱导单倍体胚乳愈伤组织的方法
CN108841778B (zh) * 2018-04-28 2022-05-17 大连普瑞康生物技术有限公司 一种红豆杉细胞组织培养物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019504A (en) * 1989-03-23 1991-05-28 The United States Of America As Represented By The Secretary Of Agriculture Production of taxol or taxol-like compounds in cell culture

Also Published As

Publication number Publication date
DE69216003D1 (de) 1997-01-30
CA2080000A1 (en) 1992-08-13
WO1992013961A1 (en) 1992-08-20
EP0529083B1 (de) 1996-12-18
JPH05507629A (ja) 1993-11-04
EP0529083A1 (de) 1993-03-03

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