DE69216003D1 - Verfahren zur herstellung von taxol mittels taxusspezies-zellkultur - Google Patents

Verfahren zur herstellung von taxol mittels taxusspezies-zellkultur

Info

Publication number
DE69216003D1
DE69216003D1 DE69216003T DE69216003T DE69216003D1 DE 69216003 D1 DE69216003 D1 DE 69216003D1 DE 69216003 T DE69216003 T DE 69216003T DE 69216003 T DE69216003 T DE 69216003T DE 69216003 D1 DE69216003 D1 DE 69216003D1
Authority
DE
Germany
Prior art keywords
taxol
callus
cell culture
cells containing
suspension culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69216003T
Other languages
English (en)
Inventor
Koji Saito
Hiroaki Ohashi
Masaaki Hibi
Makoto Tahara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Steel Corp
Original Assignee
Nippon Steel Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Steel Corp filed Critical Nippon Steel Corp
Application granted granted Critical
Publication of DE69216003D1 publication Critical patent/DE69216003D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04—Plant cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
DE69216003T 1991-02-12 1992-02-10 Verfahren zur herstellung von taxol mittels taxusspezies-zellkultur Expired - Lifetime DE69216003D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1901091 1991-02-12
PCT/JP1992/000132 WO1992013961A1 (en) 1991-02-12 1992-02-10 Process for producing taxol by cell culture of taxus species

Publications (1)

Publication Number Publication Date
DE69216003D1 true DE69216003D1 (de) 1997-01-30

Family

ID=11987535

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69216003T Expired - Lifetime DE69216003D1 (de) 1991-02-12 1992-02-10 Verfahren zur herstellung von taxol mittels taxusspezies-zellkultur

Country Status (6)

Country Link
EP (1) EP0529083B1 (de)
JP (1) JPH05507629A (de)
AT (1) ATE146527T1 (de)
CA (1) CA2080000A1 (de)
DE (1) DE69216003D1 (de)
WO (1) WO1992013961A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7264951B1 (en) 1992-02-20 2007-09-04 Phyton, Inc. Enhanced production of taxol and taxanes by cell cultures of Taxus species
US5407816A (en) * 1992-02-20 1995-04-18 Phyton Catalytic, Inc. Enhanced production of taxol and taxanes by cell cultures of taxus species
CA2434692A1 (en) * 1992-04-07 1993-10-08 Paul M. Cino Callus cell induction and the preparation of taxanes
EP0642586A4 (de) * 1992-05-21 1995-11-29 Penn State Res Found IN KULTUR GEHALTENES -i(TAXUS) GEWEBE ALS QUELLE VON TAXOL, VERWANDTEN TAXANEN UND ANDEREN NEUEN ANTI-TUMOR/ANTI-VIRALEN STOFFEN(20.01.94).
US5279949A (en) * 1992-12-07 1994-01-18 Board Of Trustees Operating Michigan State University Process for the isolation and purification of taxol and taxanes from Taxus spp
KR950005081B1 (ko) * 1993-07-06 1995-05-18 산림청임목육종연구소 주목 종자의 씨눈 유래의 체세포배 및 체세포배성세포 혹은 그 배양배지로부터 택솔(Taxol) 및 그 유도체를 생산하는 방법
US5547866A (en) * 1994-07-20 1996-08-20 The Regents Of The University Of California Taxane production in haploid-derived cell cultures
KR960037826A (ko) * 1995-04-27 1996-11-19 김경환 택서스속 식물세포의 반연속식 배양방법
DK0954596T3 (da) 1996-05-24 2006-05-15 Phyton Inc Foröget produktion af taxaner ved celledyrkning af Taxus-art
CN102687667B (zh) * 2012-06-19 2013-09-04 湖南农业大学 一种红豆杉成熟胚乳诱导单倍体胚乳愈伤组织的方法
CN108841778B (zh) * 2018-04-28 2022-05-17 大连普瑞康生物技术有限公司 一种红豆杉细胞组织培养物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019504A (en) * 1989-03-23 1991-05-28 The United States Of America As Represented By The Secretary Of Agriculture Production of taxol or taxol-like compounds in cell culture

Also Published As

Publication number Publication date
EP0529083A1 (de) 1993-03-03
ATE146527T1 (de) 1997-01-15
JPH05507629A (ja) 1993-11-04
EP0529083B1 (de) 1996-12-18
CA2080000A1 (en) 1992-08-13
WO1992013961A1 (en) 1992-08-20

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Legal Events

Date Code Title Description
8332 No legal effect for de