ATE195146T1 - Erhöhte produktion von taxol und taxanen mittels -taxus-spezifische zellkulturen - Google Patents

Erhöhte produktion von taxol und taxanen mittels -taxus-spezifische zellkulturen

Info

Publication number
ATE195146T1
ATE195146T1 AT93906156T AT93906156T ATE195146T1 AT E195146 T1 ATE195146 T1 AT E195146T1 AT 93906156 T AT93906156 T AT 93906156T AT 93906156 T AT93906156 T AT 93906156T AT E195146 T1 ATE195146 T1 AT E195146T1
Authority
AT
Austria
Prior art keywords
taxus
taxans
taxols
cell cultures
specific cell
Prior art date
Application number
AT93906156T
Other languages
English (en)
Inventor
Venkataraman Bringi
Prakash G Kadkade
Original Assignee
Phyton Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27126086&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE195146(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Phyton Inc filed Critical Phyton Inc
Application granted granted Critical
Publication of ATE195146T1 publication Critical patent/ATE195146T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • C12N5/0025Culture media for plant cell or plant tissue culture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04Plant cells or tissues

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT93906156T 1992-02-20 1993-02-22 Erhöhte produktion von taxol und taxanen mittels -taxus-spezifische zellkulturen ATE195146T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83914492A 1992-02-20 1992-02-20
US07/874,344 US5407816A (en) 1992-02-20 1992-04-24 Enhanced production of taxol and taxanes by cell cultures of taxus species
PCT/US1993/001576 WO1993017121A1 (en) 1992-02-20 1993-02-22 Enhanced production of taxol and taxanes by cell cultures of taxus species

Publications (1)

Publication Number Publication Date
ATE195146T1 true ATE195146T1 (de) 2000-08-15

Family

ID=27126086

Family Applications (3)

Application Number Title Priority Date Filing Date
AT99202507T ATE256197T1 (de) 1992-02-20 1993-02-22 Erhöhte produktion von taxol und taxanen mittels taxus-spezies-zellkulturen
AT93906156T ATE195146T1 (de) 1992-02-20 1993-02-22 Erhöhte produktion von taxol und taxanen mittels -taxus-spezifische zellkulturen
AT03021426T ATE504659T1 (de) 1992-02-20 1993-02-22 Erhöhte produktion von taxol und taxanen mittels taxus-spezies-zellkulturen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT99202507T ATE256197T1 (de) 1992-02-20 1993-02-22 Erhöhte produktion von taxol und taxanen mittels taxus-spezies-zellkulturen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT03021426T ATE504659T1 (de) 1992-02-20 1993-02-22 Erhöhte produktion von taxol und taxanen mittels taxus-spezies-zellkulturen

Country Status (16)

Country Link
US (1) US5407816A (de)
EP (3) EP0960944B1 (de)
JP (5) JP3513151B2 (de)
KR (6) KR100285788B1 (de)
AT (3) ATE256197T1 (de)
AU (1) AU672194B2 (de)
CA (1) CA2130745C (de)
DE (3) DE69333358T2 (de)
DK (2) DK0960944T3 (de)
ES (3) ES2150938T3 (de)
GR (1) GR3034722T3 (de)
HK (2) HK1003718A1 (de)
NZ (1) NZ249734A (de)
PT (2) PT672162E (de)
SG (1) SG46427A1 (de)
WO (1) WO1993017121A1 (de)

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US5850032A (en) * 1992-04-01 1998-12-15 Union Camp Corporation Method for production of plant biological products in precocious neomorphic embryoids
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JP2967532B2 (ja) * 1992-06-11 1999-10-25 日石三菱株式会社 タキサン類化合物の製造方法
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
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EP1063300B1 (de) * 1993-11-15 2003-09-03 Mitsui Chemicals, Inc. Methode zur Herstellung von Taxan-Typ Diterpen und Methode zur Gewinnung von Kulturzellen die Taxan-Typ Diterpen in hohen Ausbeuten herstellen
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EP1512398A1 (de) 1997-03-31 2005-03-09 Boston Scientific Limited Intravaskulärer Stent mit cytoskelettinhibitoren zur Vorbeugung der Restenose
US5801193A (en) * 1997-04-15 1998-09-01 Immune Modulation, Inc. Compositions and methods for immunosuppressing
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KR100266448B1 (ko) * 1997-06-26 2000-09-15 박종헌 식물세포 배양 중의 온도변화에 의한 택솔의 대량생산 방법
ATE219070T1 (de) 1998-01-14 2002-06-15 Bristol Myers Squibb Co Neue kristallkomplexe von baccatin iii mit imidazol, 2-methylimidazol or isopropanol
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CN101297028B (zh) * 2005-10-31 2016-01-20 云火公司 通过同步化植物细胞培养的次级代谢产物批量生产的稳定化方法
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CN101319199B (zh) * 2007-06-08 2010-10-27 中国科学院大连化学物理研究所 一种利用中国红豆杉细胞诱导产生紫杉烷的方法
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CN101671319B (zh) * 2009-09-18 2012-02-29 应成杰 红豆杉无毒提取物的提取工艺
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CN102715086B (zh) * 2012-06-19 2014-04-16 湖南农业大学 一种红豆杉试管苗诱导获得愈伤组织和悬浮细胞的方法
CN102715085B (zh) * 2012-06-19 2014-04-16 湖南农业大学 一种诱导红豆杉种子种胚获得愈伤组织和悬浮细胞的方法
CN103058961B (zh) * 2013-01-28 2015-04-29 普洱市红宝生物科技有限公司 从云南红豆杉中提取紫杉醇的方法
CN103570647A (zh) * 2013-11-06 2014-02-12 湖南农业大学 从红豆杉细胞培养液中制备高纯度紫杉醇的方法
KR101603539B1 (ko) * 2014-08-11 2016-03-15 영남대학교 산학협력단 택솔을 생산하는 콜레토트리쿰 데마티움 균주 및 그 용도
KR101786448B1 (ko) 2015-08-24 2017-10-18 영남대학교 산학협력단 택솔을 생산하는 트라이코더마 비리데슨스 tx1 균주 및 이의 용도
CN109022510A (zh) * 2018-08-23 2018-12-18 吉首大学 一种利用南方红豆杉菌根菌与活组织细胞共培养生产紫杉醇及10-dabⅲ的方法
CN110441439B (zh) * 2019-07-01 2022-03-01 杭州师范大学 区分密叶红豆杉和云南红豆杉的代谢标志物及其检测方法
EP4284939A1 (de) * 2021-01-28 2023-12-06 Phyto-Technics BV Herstellung von taxol aus taxus schneiden

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019504A (en) * 1989-03-23 1991-05-28 The United States Of America As Represented By The Secretary Of Agriculture Production of taxol or taxol-like compounds in cell culture
JPH03216123A (ja) * 1990-01-17 1991-09-24 Nitsusen Kagaku Kogyo Kk 培養植物体の増殖促進方法
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US5407816A (en) * 1992-02-20 1995-04-18 Phyton Catalytic, Inc. Enhanced production of taxol and taxanes by cell cultures of taxus species

Also Published As

Publication number Publication date
DE69334352D1 (de) 2011-05-19
CA2130745C (en) 2008-01-22
JP2004000285A (ja) 2004-01-08
JP2009183305A (ja) 2009-08-20
ATE504659T1 (de) 2011-04-15
HK1003718A1 (en) 1998-11-06
KR100392036B1 (ko) 2003-07-16
EP1378574A1 (de) 2004-01-07
SG46427A1 (en) 1998-02-20
GR3034722T3 (en) 2001-01-31
DE69329154T2 (de) 2001-06-07
EP1378574B1 (de) 2011-04-06
KR20090116792A (ko) 2009-11-11
EP0672162A4 (de) 1995-11-29
DK0960944T3 (da) 2004-04-05
DE69329154D1 (de) 2000-09-07
KR20040000390A (ko) 2004-01-03
EP0960944A1 (de) 1999-12-01
ES2213328T3 (es) 2004-08-16
US5407816A (en) 1995-04-18
PT672162E (pt) 2001-01-31
JP2008131955A (ja) 2008-06-12
PT960944E (pt) 2004-04-30
AU3729193A (en) 1993-09-13
KR950700996A (ko) 1995-02-20
DE69333358T2 (de) 2004-08-19
JP2005348751A (ja) 2005-12-22
HK1024936A1 (en) 2000-10-27
DK0672162T3 (da) 2000-12-18
NZ249734A (en) 1996-08-27
EP0960944B1 (de) 2003-12-10
DE69333358D1 (de) 2004-01-22
ATE256197T1 (de) 2003-12-15
ES2150938T3 (es) 2000-12-16
AU672194B2 (en) 1996-09-26
WO1993017121A1 (en) 1993-09-02
JPH07506721A (ja) 1995-07-27
CA2130745A1 (en) 1993-09-02
KR20070104684A (ko) 2007-10-26
KR100285788B1 (ko) 2001-05-02
EP0672162A1 (de) 1995-09-20
EP0672162B1 (de) 2000-08-02
JP3513151B2 (ja) 2004-03-31
KR20110079863A (ko) 2011-07-08
ES2361150T3 (es) 2011-06-14

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