GB1429184A
(en)
|
1972-04-20 |
1976-03-24 |
Allen & Hanburys Ltd |
Physically anti-inflammatory steroids for use in aerosols
|
US4044126A
(en)
|
1972-04-20 |
1977-08-23 |
Allen & Hanburys Limited |
Steroidal aerosol compositions and process for the preparation thereof
|
US4444887A
(en)
|
1979-12-10 |
1984-04-24 |
Sloan-Kettering Institute |
Process for making human antibody producing B-lymphocytes
|
US4716111A
(en)
|
1982-08-11 |
1987-12-29 |
Trustees Of Boston University |
Process for producing human antibodies
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
US5807715A
(en)
|
1984-08-27 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
|
JP2532858B2
(ja)
|
1985-04-01 |
1996-09-11 |
セルテツク リミテツド |
形質転換したミエロ―マ細胞系
|
GB8601597D0
(en)
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
US5869620A
(en)
|
1986-09-02 |
1999-02-09 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
EP0307434B2
(en)
|
1987-03-18 |
1998-07-29 |
Scotgen Biopharmaceuticals, Inc. |
Altered antibodies
|
GB8717430D0
(en)
|
1987-07-23 |
1987-08-26 |
Celltech Ltd |
Recombinant dna product
|
US5677425A
(en)
|
1987-09-04 |
1997-10-14 |
Celltech Therapeutics Limited |
Recombinant antibody
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
ATE151110T1
(de)
|
1988-09-02 |
1997-04-15 |
Protein Eng Corp |
Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen
|
US5750373A
(en)
|
1990-12-03 |
1998-05-12 |
Genentech, Inc. |
Enrichment method for variant proteins having altered binding properties, M13 phagemids, and growth hormone variants
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
US5413923A
(en)
|
1989-07-25 |
1995-05-09 |
Cell Genesys, Inc. |
Homologous recombination for universal donor cells and chimeric mammalian hosts
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
US5585112A
(en)
|
1989-12-22 |
1996-12-17 |
Imarx Pharmaceutical Corp. |
Method of preparing gas and gaseous precursor-filled microspheres
|
WO1991010737A1
(en)
|
1990-01-11 |
1991-07-25 |
Molecular Affinities Corporation |
Production of antibodies using gene libraries
|
US5780225A
(en)
|
1990-01-12 |
1998-07-14 |
Stratagene |
Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
|
AU633698B2
(en)
|
1990-01-12 |
1993-02-04 |
Amgen Fremont Inc. |
Generation of xenogeneic antibodies
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
IT1246382B
(it)
|
1990-04-17 |
1994-11-18 |
Eurand Int |
Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
WO1992003918A1
(en)
|
1990-08-29 |
1992-03-19 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
US5698426A
(en)
|
1990-09-28 |
1997-12-16 |
Ixsys, Incorporated |
Surface expression libraries of heteromeric receptors
|
US5543390A
(en)
|
1990-11-01 |
1996-08-06 |
State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University |
Covalent microparticle-drug conjugates for biological targeting
|
JP3672306B2
(ja)
|
1991-04-10 |
2005-07-20 |
ザ スクリップス リサーチ インスティテュート |
ファージミドを使用するヘテロ二量体受容体ライブラリー
|
EP0519596B1
(en)
|
1991-05-17 |
2005-02-23 |
Merck & Co. Inc. |
A method for reducing the immunogenicity of antibody variable domains
|
EP0590067A1
(en)
|
1991-06-14 |
1994-04-06 |
Xoma Corporation |
Microbially-produced antibody fragments and their conjugates
|
EP1400536A1
(en)
|
1991-06-14 |
2004-03-24 |
Genentech Inc. |
Method for making humanized antibodies
|
US5637481A
(en)
|
1993-02-01 |
1997-06-10 |
Bristol-Myers Squibb Company |
Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell
|
US5565332A
(en)
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
ATE275198T1
(de)
|
1991-12-02 |
2004-09-15 |
Medical Res Council |
Herstellung von antikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken.
|
US5766886A
(en)
|
1991-12-13 |
1998-06-16 |
Xoma Corporation |
Modified antibody variable domains
|
GB9203459D0
(en)
|
1992-02-19 |
1992-04-08 |
Scotgen Ltd |
Antibodies with germ-line variable regions
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
GB9206422D0
(en)
|
1992-03-24 |
1992-05-06 |
Bolt Sarah L |
Antibody preparation
|
US6174666B1
(en)
|
1992-03-27 |
2001-01-16 |
The United States Of America As Represented By The Department Of Health And Human Services |
Method of eliminating inhibitory/instability regions from mRNA
|
US6010715A
(en)
|
1992-04-01 |
2000-01-04 |
Bertek, Inc. |
Transdermal patch incorporating a polymer film incorporated with an active agent
|
US6024975A
(en)
|
1992-04-08 |
2000-02-15 |
Americare International Diagnostics, Inc. |
Method of transdermally administering high molecular weight drugs with a polymer skin enhancer
|
AU4116793A
(en)
|
1992-04-24 |
1993-11-29 |
Board Of Regents, The University Of Texas System |
Recombinant production of immunoglobulin-like domains in prokaryotic cells
|
DK0656946T4
(da)
|
1992-08-21 |
2010-07-26 |
Univ Bruxelles |
Immunoglobuliner uden lette kæder
|
US6005079A
(en)
|
1992-08-21 |
1999-12-21 |
Vrije Universiteit Brussels |
Immunoglobulins devoid of light chains
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
US5837242A
(en)
|
1992-12-04 |
1998-11-17 |
Medical Research Council |
Multivalent and multispecific binding proteins, their manufacture and use
|
US6274552B1
(en)
|
1993-03-18 |
2001-08-14 |
Cytimmune Sciences, Inc. |
Composition and method for delivery of biologically-active factors
|
US5985307A
(en)
|
1993-04-14 |
1999-11-16 |
Emory University |
Device and method for non-occlusive localized drug delivery
|
US5523092A
(en)
|
1993-04-14 |
1996-06-04 |
Emory University |
Device for local drug delivery and methods for using the same
|
AU6796094A
(en)
|
1993-04-29 |
1994-11-21 |
Raymond Hamers |
Production of antibodies or (functionalized) fragments thereof derived from heavy chain immunoglobulins of (camelidae)
|
JPH08511420A
(ja)
|
1993-06-16 |
1996-12-03 |
セルテック・セラピューテイクス・リミテッド |
抗 体
|
US6004534A
(en)
|
1993-07-23 |
1999-12-21 |
Massachusetts Institute Of Technology |
Targeted polymerized liposomes for improved drug delivery
|
WO1995015982A2
(en)
|
1993-12-08 |
1995-06-15 |
Genzyme Corporation |
Process for generating specific antibodies
|
GB9326253D0
(en)
|
1993-12-23 |
1994-02-23 |
Smithkline Beecham Biolog |
Vaccines
|
US5997873A
(en)
|
1994-01-13 |
1999-12-07 |
Mount Sinai School Of Medicine Of The City University Of New York |
Method of preparation of heat shock protein 70-peptide complexes
|
WO1995020401A1
(en)
|
1994-01-31 |
1995-08-03 |
Trustees Of Boston University |
Polyclonal antibody libraries
|
DK0758383T3
(da)
|
1994-05-06 |
2007-05-29 |
Roussy Inst Gustave |
Oplöselige polypeptidfraktioner af LAG-3-proteinet; fremgangsmåde til fremstilling; terapeutisk sammensætning; antiidiotypisk antistof
|
US5516637A
(en)
|
1994-06-10 |
1996-05-14 |
Dade International Inc. |
Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
|
US5759542A
(en)
|
1994-08-05 |
1998-06-02 |
New England Deaconess Hospital Corporation |
Compositions and methods for the delivery of drugs by platelets for the treatment of cardiovascular and other diseases
|
US5660854A
(en)
|
1994-11-28 |
1997-08-26 |
Haynes; Duncan H |
Drug releasing surgical implant or dressing material
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
US6121022A
(en)
|
1995-04-14 |
2000-09-19 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
US5983134A
(en)
|
1995-04-23 |
1999-11-09 |
Electromagnetic Bracing Systems Inc. |
Electrophoretic cuff apparatus drug delivery system
|
EP1978033A3
(en)
|
1995-04-27 |
2008-12-24 |
Amgen Fremont Inc. |
Human antibodies derived from immunized xenomice
|
CA2219486A1
(en)
|
1995-04-28 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US6316652B1
(en)
|
1995-06-06 |
2001-11-13 |
Kosta Steliou |
Drug mitochondrial targeting agents
|
ATE227586T1
(de)
|
1995-07-21 |
2002-11-15 |
Applied Research Systems |
Verfahren zur erkennung, identifizierung, isolierung, selektiver markierung und zielgerichteter erkennung von th1 lymphozyten mit hilfe von lag-3 protein
|
US6167301A
(en)
|
1995-08-29 |
2000-12-26 |
Flower; Ronald J. |
Iontophoretic drug delivery device having high-efficiency DC-to-DC energy conversion circuit
|
US5935576A
(en)
|
1995-09-13 |
1999-08-10 |
Fordham University |
Compositions and methods for the treatment and prevention of neoplastic diseases using heat shock proteins complexed with exogenous antigens
|
GB9601081D0
(en)
|
1995-10-06 |
1996-03-20 |
Cambridge Antibody Tech |
Specific binding members for human transforming growth factor beta;materials and methods
|
US5989830A
(en)
|
1995-10-16 |
1999-11-23 |
Unilever Patent Holdings Bv |
Bifunctional or bivalent antibody fragment analogue
|
US6039975A
(en)
|
1995-10-17 |
2000-03-21 |
Hoffman-La Roche Inc. |
Colon targeted delivery system
|
JP2978435B2
(ja)
|
1996-01-24 |
1999-11-15 |
チッソ株式会社 |
アクリロキシプロピルシランの製造方法
|
WO1997034631A1
(en)
|
1996-03-18 |
1997-09-25 |
Board Of Regents, The University Of Texas System |
Immunoglobin-like domains with increased half lives
|
TW345603B
(en)
|
1996-05-29 |
1998-11-21 |
Gmundner Fertigteile Gmbh |
A noise control device for tracks
|
US6027947A
(en)
|
1996-08-20 |
2000-02-22 |
Ramtron International Corporation |
Partially or completely encapsulated top electrode of a ferroelectric capacitor
|
US5985317A
(en)
|
1996-09-06 |
1999-11-16 |
Theratech, Inc. |
Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
|
AU722289B2
(en)
|
1996-10-01 |
2000-07-27 |
Aptalis Pharmatech, Inc. |
Taste-masked microcapsule compositions and methods of manufacture
|
US5916771A
(en)
|
1996-10-11 |
1999-06-29 |
Abgenix, Inc. |
Production of a multimeric protein by cell fusion method
|
US6131570A
(en)
|
1998-06-30 |
2000-10-17 |
Aradigm Corporation |
Temperature controlling device for aerosol drug delivery
|
WO1998023289A1
(en)
|
1996-11-27 |
1998-06-04 |
The General Hospital Corporation |
MODULATION OF IgG BINDING TO FcRn
|
CA2616914C
(en)
|
1996-12-03 |
2012-05-29 |
Abgenix, Inc. |
Egfr-binding antibody
|
US6017540A
(en)
|
1997-02-07 |
2000-01-25 |
Fordham University |
Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes
|
US5860957A
(en)
|
1997-02-07 |
1999-01-19 |
Sarcos, Inc. |
Multipathway electronically-controlled drug delivery system
|
US6277375B1
(en)
|
1997-03-03 |
2001-08-21 |
Board Of Regents, The University Of Texas System |
Immunoglobulin-like domains with increased half-lives
|
US6120751A
(en)
|
1997-03-21 |
2000-09-19 |
Imarx Pharmaceutical Corp. |
Charged lipids and uses for the same
|
CZ294425B6
(cs)
|
1997-04-14 |
2005-01-12 |
Micromet Ag |
Způsob výroby anti-humánního antigenového receptoru, anti-humánní antigenový receptor, řetězec VH a VL, souprava pro selekci anti-humánních antigenových receptorů a farmaceutická kompozice, obsahující uvedený receptor
|
US6060082A
(en)
|
1997-04-18 |
2000-05-09 |
Massachusetts Institute Of Technology |
Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
|
US20020062010A1
(en)
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
US7951917B1
(en)
|
1997-05-02 |
2011-05-31 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
US5948433A
(en)
|
1997-08-21 |
1999-09-07 |
Bertek, Inc. |
Transdermal patch
|
US6645495B1
(en)
|
1997-08-29 |
2003-11-11 |
Antigenics, Inc. |
Compositions of saponin adjuvants and excipients
|
DE69839179T2
(de)
|
1997-10-28 |
2009-02-19 |
Bando Chemical Industries, Ltd., Kobe |
Dermatologisches pflaster und verfahren zur herstellung seiner basisschicht
|
US5948646A
(en)
|
1997-12-11 |
1999-09-07 |
Fordham University |
Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
US6048736A
(en)
|
1998-04-29 |
2000-04-11 |
Kosak; Kenneth M. |
Cyclodextrin polymers for carrying and releasing drugs
|
DE69929444T2
(de)
|
1998-08-10 |
2006-09-28 |
Antigenics Inc., Woburn |
Cpg-zusammensetzungen, saponin-adjuvantien und verfahren zu deren verwendung
|
US7109003B2
(en)
|
1998-12-23 |
2006-09-19 |
Abgenix, Inc. |
Methods for expressing and recovering human monoclonal antibodies to CTLA-4
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
KR100940380B1
(ko)
|
1999-01-15 |
2010-02-02 |
제넨테크, 인크. |
효과기 기능이 변화된 폴리펩티드 변이체
|
US6271359B1
(en)
|
1999-04-14 |
2001-08-07 |
Musc Foundation For Research Development |
Tissue-specific and pathogen-specific toxic agents and ribozymes
|
US6256533B1
(en)
|
1999-06-09 |
2001-07-03 |
The Procter & Gamble Company |
Apparatus and method for using an intracutaneous microneedle array
|
MXPA02001877A
(es)
|
1999-08-23 |
2002-08-20 |
Dana Farber Cancer Inst Inc |
Pd-1, un receptor para b7-4, y usos del mismo.
|
MXPA02001911A
(es)
|
1999-08-24 |
2003-07-21 |
Medarex Inc |
Anticuerpos ctla-4 humanos y sus usos.
|
ATE440111T1
(de)
|
1999-11-29 |
2009-09-15 |
Bac Ip B V |
Immobilisierte antigenbindende moleküle aus einer domäne
|
WO2001039722A2
(en)
|
1999-11-30 |
2001-06-07 |
Mayo Foundation For Medical Education And Research |
B7-h1, a novel immunoregulatory molecule
|
JP2003520828A
(ja)
|
2000-01-27 |
2003-07-08 |
ジェネティクス インスティテュート,エルエルシー |
Ctla4(cd152)に対する抗体、これを含む結合体、およびその使用
|
EP1125905A1
(en)
|
2000-02-16 |
2001-08-22 |
Pepscan Systems B.V. |
Segment synthesis
|
US6261595B1
(en)
|
2000-02-29 |
2001-07-17 |
Zars, Inc. |
Transdermal drug patch with attached pocket for controlled heating device
|
EP1197755A1
(en)
|
2000-10-11 |
2002-04-17 |
Pepscan Systems B.V. |
Identification of protein binding sites
|
US7658921B2
(en)
|
2000-12-12 |
2010-02-09 |
Medimmune, Llc |
Molecules with extended half-lives, compositions and uses thereof
|
ES2649037T3
(es)
|
2000-12-12 |
2018-01-09 |
Medimmune, Llc |
Moléculas con semividas prolongadas, composiciones y usos de las mismas
|
WO2002066984A2
(en)
|
2001-02-16 |
2002-08-29 |
Pepscan Systems B.V. |
Arrays for determining binding of biomolecules
|
EP1539233B1
(en)
|
2001-07-12 |
2011-04-27 |
FOOTE, Jefferson |
Super humanized antibodies
|
WO2003042402A2
(en)
|
2001-11-13 |
2003-05-22 |
Dana-Farber Cancer Institute, Inc. |
Agents that modulate immune cell activation and methods of use thereof
|
US20040014194A1
(en)
|
2002-03-27 |
2004-01-22 |
Schering Corporation |
Beta-secretase crystals and methods for preparing and using the same
|
IL149820A0
(en)
|
2002-05-23 |
2002-11-10 |
Curetech Ltd |
Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency
|
FI2206517T3
(fi)
|
2002-07-03 |
2023-10-19 |
Ono Pharmaceutical Co |
Immuunopotentioivia koostumuksia käsittäen anti-PD-L1 -vasta-aineita
|
WO2004056875A1
(en)
|
2002-12-23 |
2004-07-08 |
Wyeth |
Antibodies against pd-1 and uses therefor
|
US9068234B2
(en)
|
2003-01-21 |
2015-06-30 |
Ptc Therapeutics, Inc. |
Methods and agents for screening for compounds capable of modulating gene expression
|
AU2004217526B2
(en)
|
2003-02-28 |
2010-02-04 |
St. Jude Children's Research Hospital Inc. |
T cell regulation
|
EP1660534A2
(en)
|
2003-08-22 |
2006-05-31 |
MedImmune, Inc. |
Humanization of antibodies
|
US20090304679A1
(en)
|
2004-05-27 |
2009-12-10 |
Weidanz Jon A |
Antibodies as T cell receptor mimics, methods of production and uses thereof
|
DE102004063494A1
(de)
|
2004-12-23 |
2006-07-13 |
Tegenero Ag |
Antikörper
|
ATE551398T1
(de)
|
2005-02-16 |
2012-04-15 |
Dow Corning |
Verstärkte silikonharzfolie und herstellungsverfahren dafür
|
US20060240006A1
(en)
|
2005-04-20 |
2006-10-26 |
Chishih Chu |
Novel antibody structures derived from human germline sequences
|
EP3530736A3
(en)
|
2005-05-09 |
2019-11-06 |
ONO Pharmaceutical Co., Ltd. |
Human monoclonal antibodies to programmed death 1 (pd-1) and methods for treating cancer using anti-pd-1 antibodies alone or in combination with other immunotherapeutics
|
SI1907424T1
(sl)
|
2005-07-01 |
2015-12-31 |
E. R. Squibb & Sons, L.L.C. |
Humana monoklonska protitelesa proti programiranem smrtnem ligandu 1 (PD-L1)
|
EP1987839A1
(en)
|
2007-04-30 |
2008-11-05 |
I.N.S.E.R.M. Institut National de la Sante et de la Recherche Medicale |
Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
|
US9244059B2
(en)
|
2007-04-30 |
2016-01-26 |
Immutep Parc Club Orsay |
Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
|
AU2008266951B2
(en)
|
2007-06-18 |
2013-12-12 |
Merck Sharp & Dohme B.V. |
Antibodies to human programmed death receptor PD-1
|
EP2175884B8
(en)
|
2007-07-12 |
2017-02-22 |
GITR, Inc. |
Combination therapies employing gitr binding molecules
|
US8354847B2
(en)
|
2007-08-15 |
2013-01-15 |
Electrostatic Answers Llc |
Electrometer with in-measurement range adjustment and methods thereof for measuring electrostatic charge
|
US8227577B2
(en)
|
2007-12-21 |
2012-07-24 |
Hoffman-La Roche Inc. |
Bivalent, bispecific antibodies
|
PT2242773T
(pt)
|
2008-02-11 |
2017-09-15 |
Cure Tech Ltd |
Anticorpos monoclonais para o tratamento de tumores
|
US8168757B2
(en)
|
2008-03-12 |
2012-05-01 |
Merck Sharp & Dohme Corp. |
PD-1 binding proteins
|
BRPI0915692B8
(pt)
|
2008-07-08 |
2021-05-25 |
Incyte Corp |
compostos derivados de 1,2,5-oxadiazóis, sua forma sólida, sua composição, bem como seus usos
|
CH699192A1
(de)
|
2008-07-18 |
2010-01-29 |
Mentus Holding Ag |
Verfahren und Vorrichtung für die Aufbereitung der einem Raum zuzuführenden Luft auf eine gewünschte Temperatur und eine gewünschte Feuchtigkeit.
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
RS54233B1
(en)
|
2008-08-25 |
2015-12-31 |
Amplimmune Inc. |
PD-1 ANTAGONIST COMPOSITIONS AND PROCEDURES FOR THEIR APPLICATION
|
US8927697B2
(en)
|
2008-09-12 |
2015-01-06 |
Isis Innovation Limited |
PD-1 specific antibodies and uses thereof
|
DK2342226T3
(en)
|
2008-09-26 |
2016-09-26 |
Dana Farber Cancer Inst Inc |
HUMAN ANTI-PD-1, PD-L1 AND PD-L2 ANTIBODIES AND APPLICATIONS THEREOF
|
PA8849001A1
(es)
*
|
2008-11-21 |
2010-06-28 |
Lilly Co Eli |
Anticuerpos de c-met
|
CN108997498A
(zh)
|
2008-12-09 |
2018-12-14 |
霍夫曼-拉罗奇有限公司 |
抗-pd-l1抗体及它们用于增强t细胞功能的用途
|
GB0903325D0
(en)
|
2009-02-26 |
2009-04-08 |
Univ Aberdeen |
Antibody molecules
|
CN102471378B
(zh)
|
2009-06-26 |
2014-04-02 |
瑞泽恩制药公司 |
容易地分离的具有天然免疫球蛋白形式的双特异性抗体
|
EP3279215B1
(en)
|
2009-11-24 |
2020-02-12 |
MedImmune Limited |
Targeted binding agents against b7-h1
|
EP2512600A2
(en)
*
|
2009-12-18 |
2012-10-24 |
Amgen Inc. |
Wise binding agents and epitopes
|
US20130202623A1
(en)
|
2010-02-16 |
2013-08-08 |
Nicolas Chomont |
Pd-1 modulation and uses thereof for modulating hiv replication
|
DK2542590T4
(da)
|
2010-03-05 |
2020-07-13 |
Univ Johns Hopkins |
Sammensætninger og fremgangsmåde til målrettede immunomodulatoriske antistof-fer og fusionproteiner
|
CN102892786B
(zh)
|
2010-03-11 |
2016-03-16 |
Ucb医药有限公司 |
Pd-1抗体
|
TWI653333B
(zh)
*
|
2010-04-01 |
2019-03-11 |
安進研究(慕尼黑)有限責任公司 |
跨物種專一性之PSMAxCD3雙專一性單鏈抗體
|
GB201103955D0
(en)
|
2011-03-09 |
2011-04-20 |
Antitope Ltd |
Antibodies
|
WO2012129520A1
(en)
|
2011-03-24 |
2012-09-27 |
Texas Tech University System |
Tcr mimic antibodies as vascular targeting tools
|
US9074000B2
(en)
|
2011-04-01 |
2015-07-07 |
Memorial Sloan Kettering Cancer Center |
T cell receptor-like antibodies specific for a WT1 peptide presented by HLA-A2
|
LT2699264T
(lt)
|
2011-04-20 |
2018-07-10 |
Medimmune, Llc |
Antikūnai ir kitos molekulės, kurios jungiasi prie b7-h1 ir pd-1
|
CN103796680A
(zh)
|
2011-06-21 |
2014-05-14 |
约翰霍普金斯大学 |
用于增强针对赘生物的基于免疫的治疗的聚焦放射
|
WO2013014668A1
(en)
|
2011-07-24 |
2013-01-31 |
Curetech Ltd. |
Variants of humanized immunomodulatory monoclonal antibodies
|
US8920075B2
(en)
|
2011-09-01 |
2014-12-30 |
Halo Maritime Defense Systems, Inc. |
Marine barrier and gate
|
KR101981873B1
(ko)
|
2011-11-28 |
2019-05-23 |
메르크 파텐트 게엠베하 |
항-pd-l1 항체 및 그의 용도
|
AR090263A1
(es)
|
2012-03-08 |
2014-10-29 |
Hoffmann La Roche |
Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
|
KR20220084444A
(ko)
|
2012-05-31 |
2022-06-21 |
소렌토 쎄라퓨틱스, 인코포레이티드 |
Pd-l1에 결합하는 항원 결합 단백질
|
UY34887A
(es)
|
2012-07-02 |
2013-12-31 |
Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware |
Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos
|
CN104736174B
(zh)
|
2012-07-06 |
2019-06-14 |
根马布私人有限公司 |
具有三重突变的二聚体蛋白质
|
CN112587671A
(zh)
|
2012-07-18 |
2021-04-02 |
博笛生物科技有限公司 |
癌症的靶向免疫治疗
|
CN111499755A
(zh)
|
2012-08-03 |
2020-08-07 |
丹娜法伯癌症研究院 |
抗-pd-l1和pd-l2双结合抗体单一试剂及其使用方法
|
BR112015007672A2
(pt)
|
2012-10-04 |
2017-08-08 |
Dana Farber Cancer Inst Inc |
anticorpos anti-pd-l1 monoclonais humanos e métodos de uso
|
RS58528B1
(sr)
|
2012-12-03 |
2019-04-30 |
Bristol Myers Squibb Co |
Poboljšanje anti-kancerske aktivnosti imunomodulatornih fc fuzionih proteina
|
AR093984A1
(es)
|
2012-12-21 |
2015-07-01 |
Merck Sharp & Dohme |
Anticuerpos que se unen a ligando 1 de muerte programada (pd-l1) humano
|
US10280221B2
(en)
|
2013-03-15 |
2019-05-07 |
Glaxosmithkline Intellectual Property Development Limited |
Anti-LAG-3 binding proteins
|
AU2014259719B2
(en)
|
2013-05-02 |
2019-10-03 |
Anaptysbio, Inc. |
Antibodies directed against programmed death-1 (PD-1)
|
CA2913977C
(en)
|
2013-05-31 |
2022-11-29 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind pd-1
|
US9515982B2
(en)
|
2013-06-10 |
2016-12-06 |
Broadcom Corporation |
Method and apparatus for voice over LTE and data handling in a roaming environment
|
US9616129B2
(en)
|
2013-06-22 |
2017-04-11 |
Nitor Therapeutics |
Compositions and methods for potentiating immune response, enhancing immunotherapy, and increasing vaccine potency
|
WO2014209804A1
(en)
|
2013-06-24 |
2014-12-31 |
Biomed Valley Discoveries, Inc. |
Bispecific antibodies
|
CN104250302B
(zh)
|
2013-06-26 |
2017-11-14 |
上海君实生物医药科技股份有限公司 |
抗pd‑1抗体及其应用
|
GB201311487D0
(en)
|
2013-06-27 |
2013-08-14 |
Alligator Bioscience Ab |
Bispecific molecules
|
JP2016531907A
(ja)
|
2013-08-02 |
2016-10-13 |
アデュロ・バイオテック・ホールディングス・ヨーロッパ・ベスローテン・フエンノートシャップAduro Biotech Holdings, Europe B.V. |
免疫刺激のためのcd27アゴニストと免疫チェックポイント阻害との組み合わせ
|
EP3030322A2
(en)
|
2013-08-05 |
2016-06-15 |
Cambridge Enterprise Limited |
Inhibition of cxcr4 signaling in cancer immunotherapy
|
US10966998B2
(en)
|
2013-09-05 |
2021-04-06 |
The Johns Hopkins University |
Cancer therapy via a combination of epigenetic modulation and immune modulation
|
WO2015036394A1
(en)
|
2013-09-10 |
2015-03-19 |
Medimmune Limited |
Antibodies against pd-1 and uses thereof
|
SG11201601844TA
(en)
|
2013-09-13 |
2016-04-28 |
Beigene Ltd |
Anti-pd1 antibodies and their use as therapeutics and diagnostics
|
EP3508502B1
(en)
|
2013-09-20 |
2023-04-26 |
Bristol-Myers Squibb Company |
Combination of anti-lag-3 antibodies and anti-pd-1 antibodies to treat tumors
|
US10570204B2
(en)
|
2013-09-26 |
2020-02-25 |
The Medical College Of Wisconsin, Inc. |
Methods for treating hematologic cancers
|
AU2014339900B2
(en)
|
2013-10-25 |
2019-10-24 |
Dana-Farber Cancer Institute, Inc. |
Anti-PD-L1 monoclonal antibodies and fragments thereof
|
EA201690746A1
(ru)
|
2013-10-25 |
2016-12-30 |
Фармасайкликс Элэлси |
Лечение с применением ингибиторов тирозинкиназы брутона и иммунотерапии
|
CN104558177B
(zh)
|
2013-10-25 |
2020-02-18 |
苏州思坦维生物技术股份有限公司 |
拮抗抑制程序性死亡受体pd-1与其配体结合的单克隆抗体及其编码序列与用途
|
US9425591B2
(en)
|
2013-10-31 |
2016-08-23 |
Schneider Electric Industries Sas |
ARC deflecting and ventilation assembly for electrical enclosures and systems for ARC deflecting and ventilation
|
EP3065772A4
(en)
|
2013-11-05 |
2017-09-13 |
Cognate Bioservices, Inc. |
Combinations of checkpoint inhibitors and therapeutics to treat cancer
|
PL3081576T3
(pl)
|
2013-12-12 |
2020-03-31 |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
Przeciwciało anty pd-1, jego fragment wiążący antygen i ich zastosowanie medyczne
|
US11014987B2
(en)
|
2013-12-24 |
2021-05-25 |
Janssen Pharmaceutics Nv |
Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
|
US10407502B2
(en)
|
2014-01-15 |
2019-09-10 |
Kadmon Corporation, Llc |
Immunomodulatory agents
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗pd-l1之人類抗體
|
HRP20212033T1
(hr)
|
2014-01-28 |
2022-04-01 |
Bristol-Myers Squibb Company |
Anti-lag-3 antitijela za liječenje hematoloških maligniteta
|
CN105979961B
(zh)
|
2014-02-05 |
2020-12-18 |
西达-赛奈医疗中心 |
用于治疗癌症和感染性疾病的方法和组合物
|
PE20210168A1
(es)
|
2014-02-10 |
2021-01-28 |
Merck Patent Gmbh |
INHIBICION DIRIGIDA DEL FACTOR DE CRECIMIENTO TRANSFORMADOR ß (TGFß)
|
EP3338800A1
(en)
|
2014-02-21 |
2018-06-27 |
IDAC Theranostics, Inc. |
Therapeutic agent for solid cancer
|
WO2015131176A1
(en)
|
2014-02-28 |
2015-09-03 |
Podack Eckhard R |
Compositions, methods, and kits for treatment of cancer
|
NZ747418A
(en)
|
2014-03-12 |
2023-05-26 |
Yeda Res & Dev |
Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns
|
EP3116909B1
(en)
|
2014-03-14 |
2019-11-13 |
Novartis Ag |
Antibody molecules to lag-3 and uses thereof
|
EP3593812A3
(en)
|
2014-03-15 |
2020-05-27 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor
|
WO2015155738A2
(en)
|
2014-04-09 |
2015-10-15 |
Christopher Rudd |
Use of gsk-3 inhibitors or activators which modulate pd-1 or t-bet expression to modulate t cell immunity
|
BR112016026299A2
(pt)
|
2014-05-13 |
2018-02-20 |
Chugai Seiyaku Kabushiki Kaisha |
molécula de ligação ao antígeno redirecionado à célula t para células tendo função de imunossupressão
|
WO2015179799A1
(en)
|
2014-05-22 |
2015-11-26 |
The General Hospital Corporation |
DD1alpha RECEPTOR AND USES THEREOF IN IMMUNE DISORDERS
|
CA2947932C
(en)
|
2014-05-29 |
2021-03-30 |
Spring Bioscience Corporation |
Pd-l1 antibodies and uses thereof
|
WO2015190538A1
(ja)
|
2014-06-11 |
2015-12-17 |
Idacセラノスティクス株式会社 |
免疫チェックポイント制御剤の副作用低減方法
|
WO2015195163A1
(en)
|
2014-06-20 |
2015-12-23 |
R-Pharm Overseas, Inc. |
Pd-l1 antagonist fully human antibody
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
WO2015197874A2
(en)
|
2014-06-27 |
2015-12-30 |
Apogenix Gmbh |
Combination of cd95/cd95l inhibition and cancer immunotherapy
|
JP6526189B2
(ja)
|
2014-07-03 |
2019-06-05 |
ベイジーン リミテッド |
抗pd−l1抗体並びにその治療及び診断のための使用
|
CN112546231A
(zh)
|
2014-07-09 |
2021-03-26 |
博笛生物科技有限公司 |
用于治疗癌症的联合治疗组合物和联合治疗方法
|
CN106999577B
(zh)
|
2014-07-16 |
2021-12-21 |
特兰斯吉恩股份有限公司 |
溶瘤病毒和免疫检查点调节因子组合
|
CN105330740B
(zh)
|
2014-07-30 |
2018-08-17 |
珠海市丽珠单抗生物技术有限公司 |
抗pd-1抗体及其应用
|
CN105296433B
(zh)
|
2014-08-01 |
2018-02-09 |
中山康方生物医药有限公司 |
一种ctla4抗体、其药物组合物及其用途
|
JP6629321B2
(ja)
|
2014-08-05 |
2020-01-15 |
マブクエスト エスエーMabQuest SA |
免疫学的試薬
|
WO2016020538A1
(en)
|
2014-08-08 |
2016-02-11 |
Transgene Sa |
Hbv vaccine and antibody combination therapy to treat hbv infections
|
WO2016025645A1
(en)
|
2014-08-12 |
2016-02-18 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with il-2, a therapeutic antibody, and an immune checkpoint blocker
|
UA122395C2
(uk)
|
2014-08-19 |
2020-11-10 |
Мерк Шарп Енд Доум Корп. |
Антитіло проти tigit
|
ES2915849T3
(es)
|
2014-08-19 |
2022-06-27 |
Nat Univ Corporation Okayama Univ |
Combinación de agente bloqueante de factor inmunosupresor y fármaco antidiabético de biguanida para su uso en un método de prevención de la progresión, del tratamiento y/o de la prevención del cáncer
|
JO3663B1
(ar)
|
2014-08-19 |
2020-08-27 |
Merck Sharp & Dohme |
الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
|
SI3186283T1
(sl)
|
2014-08-29 |
2020-04-30 |
F. Hoffmann-La Roche Ag |
Kombinirana terapija z imunocitokini različice IL-2, usmerjenimi proti tumorju in protitelesi proti humanemu PD-L1
|
EP3925622A1
(en)
|
2014-09-13 |
2021-12-22 |
Novartis AG |
Combination therapies
|
CA2963281A1
(en)
|
2014-10-03 |
2016-04-07 |
Novartis Ag |
Combination therapies
|
CA2964155A1
(en)
|
2014-10-10 |
2016-04-14 |
Idera Pharmaceuticals, Inc. |
Treatment of cancer using tlr9 agonist with checkpoint inhibitors
|
EP3209382B1
(en)
|
2014-10-24 |
2020-11-25 |
Calidi Biotherapeutics, Inc. |
Combination immunotherapy approach for treatment of cancer
|
UY36390A
(es)
|
2014-11-05 |
2016-06-01 |
Flexus Biosciences Inc |
Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen
|
CN105585631B
(zh)
*
|
2014-11-12 |
2020-08-18 |
北京康乐卫士生物技术股份有限公司 |
人乳头瘤病毒16型单克隆抗体及其应用
|
WO2016077553A1
(en)
|
2014-11-13 |
2016-05-19 |
The Johns Hopkins University |
Checkpoint blockade and microsatellite instability
|
PL3221346T3
(pl)
|
2014-11-21 |
2021-03-08 |
Bristol-Myers Squibb Company |
Przeciwciała ze zmodyfikowanym regionem stałym łańcucha ciężkiego
|
WO2016090347A1
(en)
|
2014-12-05 |
2016-06-09 |
Immunext, Inc. |
Identification of vsig8 as the putative vista receptor and its use thereof to produce vista/vsig8 modulators
|
TWI595006B
(zh)
|
2014-12-09 |
2017-08-11 |
禮納特神經系統科學公司 |
抗pd-1抗體類和使用彼等之方法
|
EP3233918A1
(en)
|
2014-12-19 |
2017-10-25 |
Novartis AG |
Combination therapies
|
SG10202006538TA
(en)
|
2014-12-23 |
2020-08-28 |
Bristol Myers Squibb Co |
Antibodies to tigit
|
CA2972806A1
(en)
|
2014-12-31 |
2016-07-07 |
Anthrogenesis Corporation |
Methods of treating hematological disorders, solid tumors, or infectious diseases using natural killer cells
|
US11116838B2
(en)
|
2015-01-29 |
2021-09-14 |
The Trustees Of The University Of Pennsylvania |
Checkpoint inhibitor and vaccine combinations and use of same for immunotherapy
|
MA41460A
(fr)
|
2015-02-03 |
2017-12-12 |
Oncomed Pharm Inc |
Agents de liaison à la tnfrsf et leurs utilisations
|
MA41463A
(fr)
|
2015-02-03 |
2017-12-12 |
Anaptysbio Inc |
Anticorps dirigés contre le gène d'activation 3 des lymphocytes (lag-3)
|
CA2975432A1
(en)
|
2015-02-13 |
2016-08-18 |
Transgene Sa |
Immunotherapeutic vaccine and antibody combination therapy
|
WO2016168361A1
(en)
|
2015-04-14 |
2016-10-20 |
Polynoma, Llc |
Polyvalent vaccines and combination therapy for the treatment of melanoma
|
WO2016180781A1
(en)
|
2015-05-08 |
2016-11-17 |
Michele Maio |
Combination therapy of mesothelioma
|
TWI715587B
(zh)
|
2015-05-28 |
2021-01-11 |
美商安可美德藥物股份有限公司 |
Tigit結合劑和彼之用途
|
GB201509338D0
(en)
|
2015-05-29 |
2015-07-15 |
Bergenbio As |
Combination therapy
|
TWI773646B
(zh)
|
2015-06-08 |
2022-08-11 |
美商宏觀基因股份有限公司 |
結合lag-3的分子和其使用方法
|
CN107921018A
(zh)
|
2015-06-11 |
2018-04-17 |
生态有限公司 |
药物组合及其应用
|
WO2017013421A1
(en)
|
2015-07-20 |
2017-01-26 |
Virttu Biologics Limited |
Treatment of cancer by infusion of oncolytic herpes simplex virus to the blood
|
CN114853891A
(zh)
|
2015-07-22 |
2022-08-05 |
索伦托药业有限公司 |
与lag3结合的抗体治疗剂
|
LT3317301T
(lt)
|
2015-07-29 |
2021-07-26 |
Novartis Ag |
Kombinuotos terapijos, apimančios antikūno molekules prieš lag-3
|
AU2016303485A1
(en)
|
2015-07-31 |
2018-03-01 |
Tarveda Therapeutics, Inc. |
Compositions and methods for immunomodulation
|
US20180230431A1
(en)
|
2015-08-07 |
2018-08-16 |
Glaxosmithkline Intellectual Property Development Limited |
Combination Therapy
|
BR112018000366A2
(pt)
|
2015-08-07 |
2018-09-11 |
Pieris Pharmaceuticals Gmbh |
polipeptídeo de fusão, muteína de lipocalina, molécula de ácido nucleico, célula hospedeira, métodos de produção de um polipeptídeo de fusão, para inibir simultaneamente os pontos de controle imunes, para aumentar a atividade celular de linfócitos antitumorais e para interferir com a ligação do lag-3 humano e uso do polipeptídeo de fusão
|
EP3334465A1
(en)
|
2015-08-12 |
2018-06-20 |
Bayer Pharma Aktiengesellschaft |
Pharmaceutical combination for the treatment of cancer
|
JP6976241B2
(ja)
|
2015-08-14 |
2021-12-08 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
抗tigit抗体
|
EP3798234A1
(en)
|
2015-09-02 |
2021-03-31 |
Immutep S.A.S. |
Anti-lag-3 agonistic antibodies
|
WO2017049143A1
(en)
|
2015-09-18 |
2017-03-23 |
Dana-Farber Cancer Institute, Inc. |
Methods of reducing liver pd-1-expressing cd8+t cells using pd-1 fc fusion proteins that bind fc receptors
|
JP6764474B2
(ja)
|
2015-09-25 |
2020-09-30 |
ジェネンテック, インコーポレイテッド |
抗tigit抗体及び使用方法
|
RU2729379C1
(ru)
|
2015-10-01 |
2020-08-06 |
Потенза Терапевтикс, Инк. |
Анти-tigit антигенсвязывающие белки и способы их применения
|
TWI756187B
(zh)
|
2015-10-09 |
2022-03-01 |
美商再生元醫藥公司 |
抗lag3抗體及其用途
|
WO2017070110A1
(en)
|
2015-10-19 |
2017-04-27 |
Cold Genesys, Inc. |
Methods of treating solid or lymphatic tumors by combination therapy
|
US11059899B1
(en)
|
2015-10-22 |
2021-07-13 |
Ablynx N.V. |
Polypeptides that bind glucocorticoid-induced TNFR family-related receptor (GITR)
|
WO2017087547A1
(en)
|
2015-11-17 |
2017-05-26 |
Oncomed Pharmaceuticals, Inc. |
Pd-l1-binding agents and uses thereof
|
WO2017086367A1
(ja)
|
2015-11-18 |
2017-05-26 |
中外製薬株式会社 |
免疫抑制機能を有する細胞に対するt細胞リダイレクト抗原結合分子を用いた併用療法
|
MY189018A
(en)
|
2015-11-18 |
2022-01-19 |
Merck Sharp & Dohme |
Pd1 and/or lag3 binders
|
WO2017087901A2
(en)
|
2015-11-19 |
2017-05-26 |
Sutro Biopharma, Inc. |
Anti-lag3 antibodies, compositions comprising anti-lag3 antibodies and methods of making and using anti-lag3 antibodies
|
WO2017091611A1
(en)
|
2015-11-23 |
2017-06-01 |
Immungene, Inc |
Enhanced cancer immunotherapy using antibody-interferon fusion molecules
|
KR20180086233A
(ko)
|
2015-12-04 |
2018-07-30 |
시애틀 지네틱스, 인크. |
체크포인트 저해제와 병용되는 2-데옥시-2-플루오로-l-푸코스를 사용하는 암 치료
|
RU2018123481A
(ru)
|
2015-12-16 |
2020-01-20 |
Мерк Шарп И Доум Корп. |
Анти-lag3 антитела и антигенсвязывающие фрагменты
|
CA3006767C
(en)
|
2015-12-18 |
2024-02-06 |
University Of Pittsburgh - Of The Commonwealth System Of Higher Education |
Cancer prevention and therapy by inhibiting soluble tumor necrosis factor
|
CN106955354B
(zh)
|
2016-01-11 |
2020-06-19 |
中国科学院分子细胞科学卓越创新中心 |
用于肿瘤免疫治疗的联合用药物组合
|
EP3192805A1
(en)
|
2016-01-15 |
2017-07-19 |
Humanitas Mirasole S.p.A. |
Inhibitors of t cell activation or stimulation and uses thereof
|
US11612426B2
(en)
|
2016-01-15 |
2023-03-28 |
Immunsys, Inc. |
Immunologic treatment of cancer
|
US10918737B2
(en)
|
2016-01-28 |
2021-02-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of cancer
|
JP6902040B2
(ja)
|
2016-01-28 |
2021-07-14 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
免疫チェックポイント阻害剤の効力を増強する方法
|
WO2017133175A1
(en)
|
2016-02-04 |
2017-08-10 |
Nanjing Legend Biotech Co., Ltd. |
Engineered mammalian cells for cancer therapy
|
UA125898C2
(uk)
|
2016-03-04 |
2022-07-06 |
Джн Байосайєнсіз, Ллк |
Антитіла до tigit
|
EA201891983A8
(ru)
|
2016-03-04 |
2020-05-28 |
Бристол-Майерс Сквибб Компани |
Комбинированная терапия антителами к cd73
|
HRP20240052T1
(hr)
|
2016-03-04 |
2024-03-29 |
Io Biotech Aps |
Kombinirana terapija protiv raka
|
SG10201601719RA
(en)
|
2016-03-04 |
2017-10-30 |
Agency Science Tech & Res |
Anti-LAG-3 Antibodies
|
US11497781B2
(en)
|
2016-03-10 |
2022-11-15 |
Cg Oncology, Inc. |
Methods of treating bladder cancer by combination therapy comprising the oncolytic adenovirus CG0070 and an immune checkpoint inhibitor
|
WO2017160717A2
(en)
|
2016-03-15 |
2017-09-21 |
Memorial Sloan Kettering Cancer Center |
Method of treating diseases using kinase modulators
|
US20190175748A1
(en)
|
2016-03-16 |
2019-06-13 |
Amal Therapeutics Sa |
Combination of an immune checkpoint modulator and a complex comprising a cell penetrating peptide, a cargo and a tlr peptide agonist for use in medicine
|
US10894823B2
(en)
|
2016-03-24 |
2021-01-19 |
Gensun Biopharma Inc. |
Trispecific inhibitors for cancer treatment
|
SG11201808306PA
(en)
|
2016-03-24 |
2018-10-30 |
Tragara Pharmaceuticals Inc |
Treatment of cancer with tg02
|
CN109476739A
(zh)
|
2016-04-07 |
2019-03-15 |
癌症研究技术有限公司 |
用于肿瘤特异性细胞消减的抗CD25 FCγ受体双特异性抗体
|
MX2018012469A
(es)
|
2016-04-15 |
2019-07-04 |
Immunext Inc |
Anticuerpos vista antihumanos y uso de los mismos.
|
EA201892362A1
(ru)
|
2016-04-18 |
2019-04-30 |
Селлдекс Терапьютикс, Инк. |
Агонистические антитела, которые связываются с cd40 человека, и варианты их применения
|
US10875919B2
(en)
|
2016-04-26 |
2020-12-29 |
Alector Llc |
Chimeric receptors and methods of use thereof
|
CA3023118A1
(en)
|
2016-05-05 |
2017-11-09 |
David Weiner |
Dna monoclonal antibodies targeting checkpoint molecules
|
SI3452053T1
(sl)
|
2016-05-06 |
2023-03-31 |
Taris Biomedical Llc |
Postopek za zdravljenje urotelijskega raka v spodnjem traktu
|
LT3458478T
(lt)
|
2016-05-18 |
2021-02-10 |
Boehringer Ingelheim International Gmbh |
Antikūnai prieš pd-1 ir lag-3, skirti vėžio gydymui
|
JP7169195B2
(ja)
|
2016-05-20 |
2022-11-10 |
バイオヘイブン・ファーマシューティカル・ホールディング・カンパニー・リミテッド |
癌を処置するためのリルゾール、リルゾールプロドラッグまたはリルゾール類似体と免疫療法との併用
|
CN109475627B
(zh)
|
2016-05-26 |
2023-01-06 |
齐鲁普吉湾生物治疗公司 |
抗体混合物
|
FR3051794A1
(fr)
|
2016-05-31 |
2017-12-01 |
Lab Francais Du Fractionnement |
Anticorps pour le traitement de cancers
|
MA45233A
(fr)
|
2016-06-10 |
2019-04-17 |
Regeneron Pharma |
Anticorps anti-gitr et leurs utilisations
|
US20170360932A1
(en)
|
2016-06-17 |
2017-12-21 |
Varian Medical Systems, Inc. |
Immune modulators in combination with radiation treatment
|
US11214618B2
(en)
|
2016-06-20 |
2022-01-04 |
F-Star Therapeutics Limited |
LAG-3 binding members
|
ES2915410T3
(es)
|
2016-06-23 |
2022-06-22 |
Jiangsu Hengrui Medicine Co |
Anticuerpo contra LAG-3, fragmento de unión a antígeno del mismo y aplicación farmacéutica del mismo
|
SG11201811237WA
(en)
|
2016-06-24 |
2019-01-30 |
Infinity Pharmaceuticals Inc |
Combination therapies
|
WO2018013534A1
(en)
|
2016-07-11 |
2018-01-18 |
Dana-Farber Cancer Institute, Inc. |
Methods for treating pten deficient epithelial cancers using a combination of anti-pi3kbeta and anti-immune checkpoint agents
|
WO2018045110A1
(en)
|
2016-08-30 |
2018-03-08 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
MX2019002925A
(es)
|
2016-09-15 |
2019-09-05 |
Idera Pharmaceuticals Inc |
Modulacion inmune con agonistas de tlr9 para el tratamiento del cancer.
|
EP3515494A4
(en)
|
2016-09-26 |
2020-10-07 |
The Brigham and Women's Hospital, Inc. |
REGULATORS OF B-LYMPHOCYTES MEDIA IMMUNOSUPPRESSION
|
KR20230133934A
(ko)
|
2016-10-11 |
2023-09-19 |
아게누스 인코포레이티드 |
항-lag-3 항체 및 이의 사용 방법
|
MX2019004241A
(es)
|
2016-10-13 |
2019-08-05 |
Symphogen As |
Composiciones y anticuerpos anti-gen 3 de activacion de linfocitos (lag-3).
|
PT3565844T
(pt)
|
2017-01-09 |
2023-05-02 |
Tesaro Inc |
Métodos de tratamento de cancro com anticorpos anti-pd-1
|
WO2018129553A1
(en)
|
2017-01-09 |
2018-07-12 |
Tesaro, Inc. |
Methods of treating cancer with anti-tim-3 antibodies
|
US11566077B2
(en)
|
2017-01-17 |
2023-01-31 |
The University Of Chicago |
Dysfunctional antigen-specific CD8+ T cells in the tumor microenvironment
|
UA126571C2
(uk)
|
2017-01-24 |
2022-11-02 |
Ай-Маб Байофарма Юес Лімітед |
Антитіло до cd73 та його застосування
|
WO2018148378A1
(en)
|
2017-02-08 |
2018-08-16 |
Dana-Farber Cancer Institute, Inc. |
Modulating biomarkers to increase tumor immunity and improve the efficiacy of cancer immunotherapy
|
KR20240011262A
(ko)
|
2017-02-21 |
2024-01-25 |
리제너론 파아마슈티컬스, 인크. |
폐암의 치료를 위한 항-pd-1 항체
|
WO2018152687A1
(en)
|
2017-02-22 |
2018-08-30 |
I-Mab |
Anti-lymphocyte activation gene-3 (lag-3) antibodies and uses thereof
|
WO2018160671A1
(en)
|
2017-02-28 |
2018-09-07 |
Harpoon Therapeutics, Inc. |
Targeted checkpoint inhibitors and methods of use
|
WO2018160754A2
(en)
|
2017-02-28 |
2018-09-07 |
Harpoon Therapeutics, Inc. |
Inducible monovalent antigen binding protein
|
US20200085944A1
(en)
|
2017-03-17 |
2020-03-19 |
Curevac Ag |
Rna vaccine and immune checkpoint inhibitors for combined anticancer therapy
|
EP3606954B1
(en)
|
2017-04-05 |
2022-07-20 |
F. Hoffmann-La Roche AG |
Anti-lag3 antibodies
|
PE20191741A1
(es)
|
2017-04-05 |
2019-12-12 |
Symphogen As |
Terapias combinadas dirigidas a pd-1, tim-3, y lag-3
|
WO2018185135A1
(en)
|
2017-04-05 |
2018-10-11 |
Boehringer Ingelheim International Gmbh |
Anticancer combination therapy
|
KR20190137911A
(ko)
|
2017-04-21 |
2019-12-11 |
신라젠(주) |
항암 백시니아 바이러스와 관문 저해제 병용 요법
|
US11845798B2
(en)
|
2017-05-02 |
2023-12-19 |
Merck Sharp & Dohme Llc |
Formulations of anti-LAG3 antibodies and co-formulations of anti-LAG3 antibodies and anti-PD-1 antibodies
|
WO2018204760A1
(en)
|
2017-05-05 |
2018-11-08 |
David Weiner |
Ctla4 antibodies and vaccine combinations and use of same for immunotherapy
|
CN110621337B
(zh)
|
2017-05-10 |
2021-11-09 |
浙江时迈药业有限公司 |
抗lag3人单克隆抗体及其用途
|
KR20200013241A
(ko)
|
2017-05-25 |
2020-02-06 |
브리스톨-마이어스 스큅 컴퍼니 |
변형된 중쇄 불변 영역을 포함하는 항체
|
WO2018219956A1
(en)
|
2017-05-29 |
2018-12-06 |
Gamamabs Pharma |
Cancer-associated immunosuppression inhibitor
|
AU2018277824A1
(en)
|
2017-05-30 |
2019-10-17 |
Bristol-Myers Squibb Company |
Treatment of LAG-3 positive tumors
|
MX2019012076A
(es)
|
2017-05-30 |
2019-12-09 |
Bristol Myers Squibb Co |
Composiciones que comprenden un anticuerpo anti gen-3 de activacion del linfocito (lag-3) o un anticuerpo anti-lag-3 y un anticuerpo anti muerte celular programada 1 (pd-1) o anti ligando 1 de muerte celular programada (pd-l1).
|
MX2019012038A
(es)
|
2017-05-30 |
2019-11-18 |
Bristol Myers Squibb Co |
Composiciones que comprenden una combinacion de un anticuerpo anti gen 3 de activacion del linfocito (lag-3), un inhibidor de la trayectoria del receptor de muerte programada 1 (pd-1), y un agente inmunoterapeutico.
|
WO2018223004A1
(en)
|
2017-06-01 |
2018-12-06 |
Xencor, Inc. |
Bispecific antibodies that bind cd20 and cd3
|
CN111344303A
(zh)
|
2017-06-01 |
2020-06-26 |
Xencor股份有限公司 |
结合cd123和cd3的双特异性抗体
|
JP6720923B2
(ja)
|
2017-06-02 |
2020-07-08 |
株式会社デンソー |
送風装置
|
CA3065836A1
(en)
|
2017-06-05 |
2018-12-13 |
The Council Of The Queensland Institute Of Medical Research |
Agents for cancer therapy or prophylaxis and uses therefor
|
CN111448323B
(zh)
|
2017-06-07 |
2023-12-01 |
长源赋能(上海)生命科技有限公司 |
精确制导的多功能治疗抗体
|
JP2020523018A
(ja)
|
2017-06-09 |
2020-08-06 |
プロビデンス ヘルス アンド サービシーズ−オレゴン |
がんの処置のための腫瘍反応性ヒトt細胞の同定のためのcd39およびcd103の使用
|
US11897953B2
(en)
|
2017-06-14 |
2024-02-13 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
JP2020524157A
(ja)
|
2017-06-20 |
2020-08-13 |
アンスティテュート キュリー |
がん併用療法における使用のためのsuv39h1ヒストンメチルトランスフェラーゼの阻害剤
|
EP3641752A4
(en)
|
2017-06-22 |
2021-03-17 |
Moonshot Pharma LLC |
CANCER TREATMENT METHODS USING COMPOSITIONS INCLUDING AMLEXANOX AND IMMUNOMODULATORS
|
EP3642240A1
(en)
|
2017-06-22 |
2020-04-29 |
Novartis AG |
Antibody molecules to cd73 and uses thereof
|
KR20220031738A
(ko)
|
2017-06-27 |
2022-03-11 |
주식회사 뉴라클사이언스 |
암 치료를 위한 항-fam19a5 항체의 용도
|
WO2019008386A1
(en)
|
2017-07-06 |
2019-01-10 |
Tusk Therapeutics Ltd |
COMPOUNDS AND METHODS FOR DEPLOYING SPECIFIC CELLS FROM A TUMOR
|
KR20200037250A
(ko)
|
2017-07-06 |
2020-04-08 |
메뤼스 엔.페. |
세포에 의해 발현되는 생물학적 활성을 조절하는 항체
|
EP3652212A4
(en)
|
2017-07-13 |
2021-04-14 |
Nanjing Leads Biolabs Co., Ltd. |
LAG-3 BINDING ANTIBODIES AND USES THEREOF
|
WO2019014665A1
(en)
|
2017-07-14 |
2019-01-17 |
Dana-Farber Cancer Institute, Inc. |
MODULATION OF BIOMARKERS TO INCREASE ANTITUMOR IMMUNITY AND IMPROVE THE EFFECTIVENESS OF ANTICANCER IMMUNOTHERAPY
|
US20200172617A1
(en)
|
2017-07-20 |
2020-06-04 |
Novartis Ag |
Dosage regimens of anti-lag-3 antibodies and uses thereof
|
WO2019020593A1
(en)
|
2017-07-25 |
2019-01-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
METHODS AND PHARMACEUTICAL COMPOSITIONS FOR MODULATION OF MONOCYTOPOISIS
|
WO2019023525A1
(en)
|
2017-07-28 |
2019-01-31 |
Dana-Farber Cancer Institute, Inc. |
ENHANCED IMMUNOTHERAPY OF CANCER USING TARGETED TRANSCRIPTION MODULATORS
|