SE503179C2 - Framställning av antihyperkolesterolemiska tetrazol- föreningar och mellanprodukter härför - Google Patents
Framställning av antihyperkolesterolemiska tetrazol- föreningar och mellanprodukter härförInfo
- Publication number
- SE503179C2 SE503179C2 SE8900565A SE8900565A SE503179C2 SE 503179 C2 SE503179 C2 SE 503179C2 SE 8900565 A SE8900565 A SE 8900565A SE 8900565 A SE8900565 A SE 8900565A SE 503179 C2 SE503179 C2 SE 503179C2
- Authority
- SE
- Sweden
- Prior art keywords
- alkyl
- formula
- hydrogen
- cyclohexyl
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Liquid Crystal Substances (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/156,865 US4824959A (en) | 1988-02-18 | 1988-02-18 | Intermediates for antihypercholesterolemic tetrazole compounds |
Publications (3)
Publication Number | Publication Date |
---|---|
SE8900565D0 SE8900565D0 (sv) | 1989-02-17 |
SE8900565L SE8900565L (sv) | 1989-08-19 |
SE503179C2 true SE503179C2 (sv) | 1996-04-15 |
Family
ID=22561419
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8900565A SE503179C2 (sv) | 1988-02-18 | 1989-02-17 | Framställning av antihyperkolesterolemiska tetrazol- föreningar och mellanprodukter härför |
SE9300595A SE9300595D0 (sv) | 1988-02-18 | 1993-02-23 | Mellanprodukter foer framstaellning av antihyperkolesterolemiska medel |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9300595A SE9300595D0 (sv) | 1988-02-18 | 1993-02-23 | Mellanprodukter foer framstaellning av antihyperkolesterolemiska medel |
Country Status (32)
Country | Link |
---|---|
US (1) | US4824959A (ja) |
JP (2) | JP2871707B2 (ja) |
KR (1) | KR970002233B1 (ja) |
CN (1) | CN1025619C (ja) |
AT (1) | AT401057B (ja) |
AU (1) | AU621586B2 (ja) |
BE (1) | BE1002136A5 (ja) |
CA (1) | CA1340430C (ja) |
CH (1) | CH680792A5 (ja) |
CY (1) | CY1874A (ja) |
DD (4) | DD285603A5 (ja) |
DE (1) | DE3904899A1 (ja) |
DK (1) | DK75289A (ja) |
EG (1) | EG19217A (ja) |
ES (1) | ES2017810A6 (ja) |
FI (1) | FI890725A (ja) |
FR (1) | FR2630112B1 (ja) |
GB (1) | GB2216121B (ja) |
GR (1) | GR1000664B (ja) |
HK (3) | HK129295A (ja) |
HU (2) | HU204045B (ja) |
IE (1) | IE65090B1 (ja) |
IT (1) | IT1230750B (ja) |
LU (1) | LU87456A1 (ja) |
MY (1) | MY106279A (ja) |
NL (1) | NL8900397A (ja) |
NO (1) | NO172439C (ja) |
NZ (1) | NZ227935A (ja) |
PT (1) | PT89748B (ja) |
SE (2) | SE503179C2 (ja) |
YU (1) | YU34189A (ja) |
ZA (1) | ZA891239B (ja) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3741509A1 (de) * | 1987-12-08 | 1989-06-22 | Hoechst Ag | Verfahren zur herstellung optisch aktiver 3-desmethylmevalonsaeurederivate sowie zwischenprodukte |
GB2244706B (en) * | 1988-02-18 | 1992-07-15 | Bristol Myers Co | Preparation of antihypercholesterolemic tetrazole intermediates |
US5010205A (en) * | 1988-08-23 | 1991-04-23 | Bristol-Myers Company | Antihypercholesterolemic tetrazol-1-yl intermediates |
US4870187A (en) * | 1988-08-23 | 1989-09-26 | Bristol-Myers Company | Antihypercholesterolemic tetrazol-1-yl compounds |
DE4128345C1 (en) * | 1991-08-27 | 1993-06-09 | Hoechst Ag, 6230 Frankfurt, De | 3R,5S 3,5,6-tri:hydroxy-hexanoic acid isopropylidene ketal derivs. prepn. - from 7-benzyl:oxy 4,6-di:hydroxy:heptene by multistage process |
US5278313A (en) * | 1992-03-27 | 1994-01-11 | E. R. Squibb & Sons, Inc. | Process for the preparation of 1,3-dioxane derivatives useful in the preparation of HMG-COA reductase inhibitors |
US5284957A (en) * | 1992-09-03 | 1994-02-08 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
CA2137049A1 (en) * | 1993-12-15 | 1995-06-16 | John K. Thottathil | Amino acid salts of and methods for preparing antihypercholesterolemic tetrazole compounds |
DE10147030A1 (de) * | 2001-09-04 | 2003-03-27 | Forschungszentrum Juelich Gmbh | Verfahren zur Trennung diastereomerer 1,3-Diol-Acetale |
US20050272808A1 (en) * | 2004-05-11 | 2005-12-08 | Nadav Zamir | Compositions and methods for the treatment of hypertension |
WO2005107739A1 (en) * | 2004-05-11 | 2005-11-17 | Darley Pharmaceuticals Ltd. | Spiroderivatives for the treatment of hypertension |
CN104303915B (zh) * | 2014-08-25 | 2016-05-25 | 李世峰 | 一种机插水稻水浮式育秧技术 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58225085A (ja) * | 1982-06-24 | 1983-12-27 | Nippon Kayaku Co Ltd | アセタ−ルグリコ−ルジアクリレ−トおよびその製造法 |
US4808621A (en) * | 1986-07-07 | 1989-02-28 | Warner-Lambert Company | Trans-6-[2-(N-heteroaryl-3,5-disubstituted)pyrazol-4-yl)-ethyl]- or ethenyl]tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
US4837205A (en) * | 1986-09-02 | 1989-06-06 | Merck & Co., Inc. | Prodrugs of antihypercholesterolemic compounds |
US4897490A (en) * | 1987-02-25 | 1990-01-30 | Bristol-Meyers Company | Antihypercholesterolemic tetrazole compounds |
US4751229A (en) * | 1987-07-09 | 1988-06-14 | Warner-Lambert Company | Treating fungal infections with substituted-(6-(tetrahydro-4-hydroxy-2-oxo-2H-pyran-2-yl)ethyl)- or ethenyl)pyrazoles |
DE3807929A1 (de) * | 1988-03-10 | 1989-09-28 | Basf Ag | Verfahren zur herstellung von reliefformen |
-
1988
- 1988-02-18 US US07/156,865 patent/US4824959A/en not_active Expired - Lifetime
-
1989
- 1989-01-24 FR FR898900786A patent/FR2630112B1/fr not_active Expired - Lifetime
- 1989-02-10 NZ NZ227935A patent/NZ227935A/xx unknown
- 1989-02-15 EG EG7689A patent/EG19217A/xx active
- 1989-02-15 YU YU00341/89A patent/YU34189A/xx unknown
- 1989-02-15 ES ES8900538A patent/ES2017810A6/es not_active Expired - Fee Related
- 1989-02-15 FI FI890725A patent/FI890725A/fi not_active Application Discontinuation
- 1989-02-16 MY MYPI89000188A patent/MY106279A/en unknown
- 1989-02-16 GB GB8903604A patent/GB2216121B/en not_active Expired - Lifetime
- 1989-02-16 HU HU895307A patent/HU204045B/hu not_active IP Right Cessation
- 1989-02-16 NO NO890661A patent/NO172439C/no not_active IP Right Cessation
- 1989-02-16 CA CA000591211A patent/CA1340430C/en not_active Expired - Fee Related
- 1989-02-16 HU HU89781A patent/HU209905B/hu unknown
- 1989-02-17 AU AU30075/89A patent/AU621586B2/en not_active Expired
- 1989-02-17 SE SE8900565A patent/SE503179C2/sv not_active IP Right Cessation
- 1989-02-17 DK DK075289A patent/DK75289A/da not_active Application Discontinuation
- 1989-02-17 PT PT89748A patent/PT89748B/pt not_active IP Right Cessation
- 1989-02-17 DD DD89334043A patent/DD285603A5/de unknown
- 1989-02-17 CN CN89100852A patent/CN1025619C/zh not_active Expired - Lifetime
- 1989-02-17 DD DD89334039A patent/DD285600A5/de unknown
- 1989-02-17 AT AT0036189A patent/AT401057B/de not_active IP Right Cessation
- 1989-02-17 DD DD89325844A patent/DD283618A5/de unknown
- 1989-02-17 GR GR890100095A patent/GR1000664B/el not_active IP Right Cessation
- 1989-02-17 IT IT8919474A patent/IT1230750B/it active
- 1989-02-17 BE BE8900162A patent/BE1002136A5/fr active
- 1989-02-17 ZA ZA891239A patent/ZA891239B/xx unknown
- 1989-02-17 DE DE3904899A patent/DE3904899A1/de not_active Ceased
- 1989-02-17 DD DD89334042A patent/DD285602A5/de unknown
- 1989-02-17 IE IE52389A patent/IE65090B1/en not_active IP Right Cessation
- 1989-02-17 JP JP1038142A patent/JP2871707B2/ja not_active Expired - Fee Related
- 1989-02-17 NL NL8900397A patent/NL8900397A/nl active Search and Examination
- 1989-02-17 KR KR1019890001890A patent/KR970002233B1/ko not_active IP Right Cessation
- 1989-02-17 CH CH572/89A patent/CH680792A5/de not_active IP Right Cessation
- 1989-02-17 LU LU87456A patent/LU87456A1/fr unknown
-
1993
- 1993-02-23 SE SE9300595A patent/SE9300595D0/xx not_active Application Discontinuation
-
1995
- 1995-08-17 HK HK129295A patent/HK129295A/xx not_active IP Right Cessation
- 1995-08-17 HK HK129395A patent/HK129395A/xx not_active IP Right Cessation
-
1996
- 1996-03-21 HK HK47596A patent/HK47596A/xx not_active IP Right Cessation
- 1996-04-05 CY CY187496A patent/CY1874A/xx unknown
-
1998
- 1998-04-28 JP JP10118511A patent/JP2922887B2/ja not_active Expired - Lifetime
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NUG | Patent has lapsed |