DK75289A - Fremgangsmaade til fremstilling af antihypercholesterolemiske tetrazolforbindelser og mellemprodukter derved - Google Patents

Fremgangsmaade til fremstilling af antihypercholesterolemiske tetrazolforbindelser og mellemprodukter derved

Info

Publication number
DK75289A
DK75289A DK075289A DK75289A DK75289A DK 75289 A DK75289 A DK 75289A DK 075289 A DK075289 A DK 075289A DK 75289 A DK75289 A DK 75289A DK 75289 A DK75289 A DK 75289A
Authority
DK
Denmark
Prior art keywords
tetrazolic
antihypercholesterolemic
intermediates
compounds
procedure
Prior art date
Application number
DK075289A
Other languages
English (en)
Other versions
DK75289D0 (da
Inventor
William Teh-Wei Han
John Jessen Wright
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DK75289D0 publication Critical patent/DK75289D0/da
Publication of DK75289A publication Critical patent/DK75289A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
DK075289A 1988-02-18 1989-02-17 Fremgangsmaade til fremstilling af antihypercholesterolemiske tetrazolforbindelser og mellemprodukter derved DK75289A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/156,865 US4824959A (en) 1988-02-18 1988-02-18 Intermediates for antihypercholesterolemic tetrazole compounds

Publications (2)

Publication Number Publication Date
DK75289D0 DK75289D0 (da) 1989-02-17
DK75289A true DK75289A (da) 1989-08-19

Family

ID=22561419

Family Applications (1)

Application Number Title Priority Date Filing Date
DK075289A DK75289A (da) 1988-02-18 1989-02-17 Fremgangsmaade til fremstilling af antihypercholesterolemiske tetrazolforbindelser og mellemprodukter derved

Country Status (32)

Country Link
US (1) US4824959A (da)
JP (2) JP2871707B2 (da)
KR (1) KR970002233B1 (da)
CN (1) CN1025619C (da)
AT (1) AT401057B (da)
AU (1) AU621586B2 (da)
BE (1) BE1002136A5 (da)
CA (1) CA1340430C (da)
CH (1) CH680792A5 (da)
CY (1) CY1874A (da)
DD (4) DD285600A5 (da)
DE (1) DE3904899A1 (da)
DK (1) DK75289A (da)
EG (1) EG19217A (da)
ES (1) ES2017810A6 (da)
FI (1) FI890725A (da)
FR (1) FR2630112B1 (da)
GB (1) GB2216121B (da)
GR (1) GR1000664B (da)
HK (3) HK129395A (da)
HU (2) HU209905B (da)
IE (1) IE65090B1 (da)
IT (1) IT1230750B (da)
LU (1) LU87456A1 (da)
MY (1) MY106279A (da)
NL (1) NL8900397A (da)
NO (1) NO172439C (da)
NZ (1) NZ227935A (da)
PT (1) PT89748B (da)
SE (2) SE503179C2 (da)
YU (1) YU34189A (da)
ZA (1) ZA891239B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3741509A1 (de) * 1987-12-08 1989-06-22 Hoechst Ag Verfahren zur herstellung optisch aktiver 3-desmethylmevalonsaeurederivate sowie zwischenprodukte
GB2244706B (en) * 1988-02-18 1992-07-15 Bristol Myers Co Preparation of antihypercholesterolemic tetrazole intermediates
US5010205A (en) * 1988-08-23 1991-04-23 Bristol-Myers Company Antihypercholesterolemic tetrazol-1-yl intermediates
US4870187A (en) * 1988-08-23 1989-09-26 Bristol-Myers Company Antihypercholesterolemic tetrazol-1-yl compounds
DE4128345C1 (en) * 1991-08-27 1993-06-09 Hoechst Ag, 6230 Frankfurt, De 3R,5S 3,5,6-tri:hydroxy-hexanoic acid isopropylidene ketal derivs. prepn. - from 7-benzyl:oxy 4,6-di:hydroxy:heptene by multistage process
US5278313A (en) * 1992-03-27 1994-01-11 E. R. Squibb & Sons, Inc. Process for the preparation of 1,3-dioxane derivatives useful in the preparation of HMG-COA reductase inhibitors
US5284957A (en) * 1992-09-03 1994-02-08 Eli Lilly And Company Excitatory amino acid receptor antagonists
CA2137049A1 (en) * 1993-12-15 1995-06-16 John K. Thottathil Amino acid salts of and methods for preparing antihypercholesterolemic tetrazole compounds
DE10147030A1 (de) * 2001-09-04 2003-03-27 Forschungszentrum Juelich Gmbh Verfahren zur Trennung diastereomerer 1,3-Diol-Acetale
EP1746988A1 (en) * 2004-05-11 2007-01-31 Darley Pharmaceuticals Ltd. Spiroderivatives for the treatment of hypertension
US20050272808A1 (en) * 2004-05-11 2005-12-08 Nadav Zamir Compositions and methods for the treatment of hypertension
CN104303915B (zh) * 2014-08-25 2016-05-25 李世峰 一种机插水稻水浮式育秧技术

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58225085A (ja) * 1982-06-24 1983-12-27 Nippon Kayaku Co Ltd アセタ−ルグリコ−ルジアクリレ−トおよびその製造法
US4808621A (en) * 1986-07-07 1989-02-28 Warner-Lambert Company Trans-6-[2-(N-heteroaryl-3,5-disubstituted)pyrazol-4-yl)-ethyl]- or ethenyl]tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis
US4837205A (en) * 1986-09-02 1989-06-06 Merck & Co., Inc. Prodrugs of antihypercholesterolemic compounds
US4897490A (en) * 1987-02-25 1990-01-30 Bristol-Meyers Company Antihypercholesterolemic tetrazole compounds
US4751229A (en) * 1987-07-09 1988-06-14 Warner-Lambert Company Treating fungal infections with substituted-(6-(tetrahydro-4-hydroxy-2-oxo-2H-pyran-2-yl)ethyl)- or ethenyl)pyrazoles
DE3807929A1 (de) * 1988-03-10 1989-09-28 Basf Ag Verfahren zur herstellung von reliefformen

Also Published As

Publication number Publication date
CN1025619C (zh) 1994-08-10
HK129295A (en) 1995-08-24
ATA36189A (de) 1995-10-15
JP2871707B2 (ja) 1999-03-17
GB8903604D0 (en) 1989-04-05
IT1230750B (it) 1991-10-29
SE8900565L (sv) 1989-08-19
DD285600A5 (de) 1990-12-19
HUT50809A (en) 1990-03-28
NO172439B (no) 1993-04-13
GR1000664B (el) 1992-09-25
FI890725A (fi) 1989-08-19
US4824959A (en) 1989-04-25
DE3904899A1 (de) 1989-08-31
HK129395A (en) 1995-08-24
HU209905B (en) 1994-11-28
CN1036013A (zh) 1989-10-04
FR2630112B1 (fr) 1994-07-29
JPH01249771A (ja) 1989-10-05
NO890661D0 (no) 1989-02-16
CY1874A (en) 1996-04-05
FR2630112A1 (fr) 1989-10-20
AT401057B (de) 1996-06-25
PT89748A (pt) 1989-10-04
CA1340430C (en) 1999-03-09
PT89748B (pt) 1994-05-31
JPH115791A (ja) 1999-01-12
NZ227935A (en) 1990-07-26
SE9300595D0 (sv) 1993-02-23
DD285602A5 (de) 1990-12-19
IE65090B1 (en) 1995-10-04
KR890012992A (ko) 1989-09-20
AU3007589A (en) 1989-08-24
BE1002136A5 (fr) 1990-07-24
DD283618A5 (de) 1990-10-17
NO890661L (no) 1989-08-21
LU87456A1 (fr) 1989-09-20
GB2216121B (en) 1992-07-15
ZA891239B (en) 1991-12-24
SE8900565D0 (sv) 1989-02-17
DK75289D0 (da) 1989-02-17
IE890523L (en) 1989-08-18
YU34189A (en) 1991-02-28
EG19217A (en) 1995-09-30
NO172439C (no) 1993-07-21
IT8919474A0 (it) 1989-02-17
KR970002233B1 (ko) 1997-02-26
HU204045B (en) 1991-11-28
HK47596A (en) 1996-03-29
DD285603A5 (de) 1990-12-19
ES2017810A6 (es) 1991-03-01
MY106279A (en) 1995-04-29
GB2216121A (en) 1989-10-04
JP2922887B2 (ja) 1999-07-26
CH680792A5 (da) 1992-11-13
AU621586B2 (en) 1992-03-19
SE503179C2 (sv) 1996-04-15
FI890725A0 (fi) 1989-02-15
NL8900397A (nl) 1989-09-18
SE9300595A0 (sv) 1993-02-23
HUT50167A (en) 1989-12-28

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