RU2020103379A - Новые молекулы нуклеиновых кислот - Google Patents
Новые молекулы нуклеиновых кислот Download PDFInfo
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| SMT202200355T1 (it) * | 2011-12-16 | 2022-11-18 | Modernatx Inc | Composizioni di mrna modificato |
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| DE202016009003U1 (de) | 2015-05-29 | 2021-05-28 | Curevac Real Estate Gmbh | Zusammensetzung umfassend in vitro transkribierte RNA erhältlich durch ein Verfahren zur Herstellung und Reinigung von RNA mit mindestens einem Schritt mit einer tangentialen Flussfiltration |
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| JP2020513824A (ja) | 2017-03-24 | 2020-05-21 | キュアバック アーゲー | Ｃｒｉｓｐｒ関連タンパク質をコードする核酸、及びその使用 |
| US11357856B2 (en) | 2017-04-13 | 2022-06-14 | Acuitas Therapeutics, Inc. | Lipids for delivery of active agents |
| CN108728477B (zh) * | 2017-04-24 | 2022-02-22 | 华东理工大学 | 一种高效的转座突变系统及构建方法 |
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| WO2019005822A1 (en) | 2017-06-28 | 2019-01-03 | The Cleveland Clinic Foundation | TREATMENT OF AN INJURY OF THE NERVOUS SYSTEM AND NEURODEGENERATIVE DISORDERS AND ASSOCIATED DISORDERS |
| JP2020530759A (ja) | 2017-07-07 | 2020-10-29 | イマティクス バイオテクノロジーズ ゲーエムベーハー | Ｎｓｃｌｃ、ｓｃｌｃ、およびその他のがんをはじめとする肺がんに対する免疫療法で使用するための新規ペプチドおよびペプチド併用 |
| EP3673069A1 (en) | 2017-08-22 | 2020-07-01 | CureVac AG | Bunyavirales vaccine |
| JP2021502079A (ja) | 2017-11-08 | 2021-01-28 | キュアバック アーゲー | ＲＮＡ配列の適合（Ａｄａｐｔａｔｉｏｎ） |
| EP3723796A1 (en) | 2017-12-13 | 2020-10-21 | CureVac AG | Flavivirus vaccine |
| CN111511928A (zh) | 2017-12-21 | 2020-08-07 | 库瑞瓦格股份公司 | 偶联到单一支持物或标签的线性双链dna和用于制备所述线性双链dna的方法 |
| DE202019006108U1 (de) | 2018-04-17 | 2024-12-16 | CureVac SE | Neue RSV-RNA-Moleküle und Zusammensetzungen für die Impfung |
| EP3814495B1 (en) | 2018-06-28 | 2023-06-07 | CureVac RNA Printer GmbH | Bioreactor for rna in vitro transcription |
| US10925947B2 (en) | 2018-06-29 | 2021-02-23 | Immatics Biotechnologies Gmbh | A*03 restricted peptides for use in immunotherapy against cancers and related methods |
| TW202024121A (zh) | 2018-09-18 | 2020-07-01 | 德商英麥提克生物技術股份有限公司 | A*01 限制肽和肽組合物在抗癌免疫治療中的用途和相關方法 |
| TW202039534A (zh) * | 2018-12-14 | 2020-11-01 | 美商美國禮來大藥廠 | KRAS變體mRNA分子 |
| WO2020127959A1 (en) | 2018-12-21 | 2020-06-25 | Curevac Ag | Methods for rna analysis |
| EP3683229A1 (en) * | 2019-01-21 | 2020-07-22 | Charité - Universitätsmedizin Berlin | Specific t cell receptors against epitopes of mutant myd88l265p protein for adoptive t cell therapy |
| CN111466338B (zh) * | 2019-01-23 | 2022-03-22 | 中国科学院广州生物医药与健康研究院 | Ddx5基因缺失的生精障碍小鼠模型及其构建方法 |
| US20220177891A1 (en) * | 2019-02-19 | 2022-06-09 | Board Of Regents, The University Of Texas System | Hipk inhibitors and methods of use thereof |
| CN109777783B (zh) * | 2019-02-20 | 2023-07-04 | 上海尚泰生物技术有限公司 | 表达cxcr2的car-nk92细胞、制备方法及其应用 |
| CN111620934B (zh) * | 2019-02-26 | 2022-03-08 | 中国科学院遗传与发育生物学研究所 | 蛋白GmHSFB2b在调控植物黄酮类化合物积累中应用 |
| CN110093419B (zh) * | 2019-04-26 | 2023-10-27 | 北京大学深圳医院 | 环状rna的应用、试剂盒和药物组合物及其应用 |
| CN114072175A (zh) * | 2019-07-04 | 2022-02-18 | 江苏康宁杰瑞生物制药有限公司 | 治疗肿瘤的物质和方法 |
| CN112175062B (zh) * | 2019-07-05 | 2022-07-15 | 中国医学科学院基础医学研究所 | Sft2b蛋白线性抗原表位以及其在精神分裂症诊断中的用途 |
| WO2021041541A1 (en) * | 2019-08-28 | 2021-03-04 | The Board Of Trustees Of The Leland Stanford Junior University | Modified circular rnas and methods of use thereof |
| WO2021081058A1 (en) * | 2019-10-21 | 2021-04-29 | Translate Bio, Inc. | Compositions, methods and uses of messenger rna |
| KR20220113485A (ko) * | 2019-12-11 | 2022-08-12 | 아벨리노 랩 유에스에이, 인크. | 짧은 간섭 rna를 사용한 r124h 돌연변이에 의한 형질전환 성장 인자 베타 유도된 유전자의 대립유전자-특이적 사일런싱 |
| CN111057690A (zh) * | 2019-12-23 | 2020-04-24 | 维塔恩(广州)医药有限公司 | 肿瘤相关基因braf突变相关抗原短肽及其应用 |
| US12194089B2 (en) | 2020-02-04 | 2025-01-14 | CureVac SE | Coronavirus vaccine |
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| CN111647598B (zh) * | 2020-02-11 | 2022-09-06 | 昆明医科大学 | 一种抑制hsa_circ_0027477表达的siRNA及其应用 |
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| CN111337678B (zh) * | 2020-02-21 | 2023-06-06 | 杭州凯保罗生物科技有限公司 | 与肿瘤免疫治疗效果相关的生物标志物及其应用 |
| CN113874507A (zh) | 2020-04-09 | 2021-12-31 | 苏州艾博生物科技有限公司 | 冠状病毒的核酸疫苗 |
| EP4175967A2 (en) | 2020-07-02 | 2023-05-10 | Life Technologies Corporation | Trinucleotide cap analogs, preparation and uses thereof |
| CN111840303A (zh) * | 2020-07-15 | 2020-10-30 | 天津大学 | 胞质羧肽酶抑制剂及其应用 |
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2023
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| KR102761594B1 (ko) | 2025-02-03 |
| ES3013993T3 (en) | 2025-04-16 |
| EP3424524A2 (en) | 2019-01-09 |
| JP2023123739A (ja) | 2023-09-05 |
| US20190040378A1 (en) | 2019-02-07 |
| JP2020530980A (ja) | 2020-11-05 |
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| CN111328287A (zh) | 2020-06-23 |
| JP7722629B2 (ja) | 2025-08-13 |
| WO2019008001A1 (en) | 2019-01-10 |
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| US10988754B2 (en) | 2021-04-27 |
| AU2018298422A1 (en) | 2019-12-19 |
| BR112019028280A2 (pt) | 2020-07-14 |
| EP3424524A3 (en) | 2019-02-27 |
| AU2018298422B2 (en) | 2023-04-06 |
| EP4494652A3 (en) | 2025-05-14 |
| EP3648791A1 (en) | 2020-05-13 |
| SG11201911430PA (en) | 2020-01-30 |
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