RO121338B1 - Derivaţi de benzensulfonamidă, procedeu de preparare a acestora, compoziţie farmaceutică şi utilizarea ca inhibitori de cox-2 - Google Patents

Derivaţi de benzensulfonamidă, procedeu de preparare a acestora, compoziţie farmaceutică şi utilizarea ca inhibitori de cox-2 Download PDF

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Publication number
RO121338B1
RO121338B1 RO98-01469A RO9801469A RO121338B1 RO 121338 B1 RO121338 B1 RO 121338B1 RO 9801469 A RO9801469 A RO 9801469A RO 121338 B1 RO121338 B1 RO 121338B1
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RO
Romania
Prior art keywords
phenyl
sulfonyl
methyl
phenylisoxazol
acetamide
Prior art date
Application number
RO98-01469A
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English (en)
Romanian (ro)
Inventor
John J. Talley
James W. Malecha
Stephen Bertenshaw
Matthew J. Graneto
Jeffery S. Carter
Jinglin Li
Srinivasan Nagarajan
David L. Brown
Donald J. Rogier Jr.
Thomas D. Penning
Ish K. Khanna
Xiangdong Xu
Richard M. Weier
Original Assignee
G.D. Searle & Co.
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Publication date
Application filed by G.D. Searle & Co. filed Critical G.D. Searle & Co.
Publication of RO121338B1 publication Critical patent/RO121338B1/ro

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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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RO98-01469A 1996-04-12 1997-04-11 Derivaţi de benzensulfonamidă, procedeu de preparare a acestora, compoziţie farmaceutică şi utilizarea ca inhibitori de cox-2 RO121338B1 (ro)

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